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Found 216 Enz. Inhib. hit(s) with Target = 'Retinoid isomerohydrolase'
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580509(CHEMBL5083918)
Affinity DataIC50:  50nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323439(3-(3-(2-Ethylbutoxy)Phenyl)Propan-I-Amine | US1018...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323440(3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-1-On...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323441(1-Amino-3-(3-(Cyclohexylmethoxy)Phenyl)Propan-2-Ol...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323442(2-(3-(Cyclohexylmethoxy)Phenoxy)Ethanamine | US101...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323444(2-(3-(Cycloheptylmethoxy)Phenoxy)Ethanamine | US10...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323445(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol |...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323446(1-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Cycl...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323447(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323448(4-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Hept...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323449(2-(3-(2-Propylpentyloxy)Phenoxy)Ethanamine | US101...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323450((S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323451(3-((3-(3-Aminopropyl)Phenoxy)Methyl)Pentan-3-Ol | ...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323452(2-(3-(2-Ethylbutoxy)Phenoxy)Ethanamine | US1018861...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323453(3-Amino-1-(3-(Benzyloxy)Phenyl)Propan-1-Ol | US101...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323454(2-(3-(Isopentyloxy)Phenoxy)Ethanamine | US10188615...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323455(2-(3-Phenethoxyphenoxy)Ethanamine | US10188615, Ex...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323456((1R,2R)-2-(Aminomethyl)-1-(3-(Cyclohexylmethoxy)Ph...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323457(3-Amino-1-(3-Phenethoxyphenyl)Propan-1-Ol | US1018...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323458((S)-1-Amino-3-(3-(2-Ethylbutoxy)Phenyl)Propan-2-Ol...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323459((S)-1-Amino-3-(3-(2-Propylpentyloxy)Phenyl)Propan-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323460((R)-1-Amino-3-(3-(2-Propylpentyloxy)Phenyl)Propan-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323461((R)-1-Amino-3-(3-(2-Ethylbutoxy)Phenyl)Propan-2-Ol...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323462(3-Amino-1-(3-(Cyclopropylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323463((1S,2S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)-2-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323464((1R,2S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)-2-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323465(3-(3-(Cyclohexylmethoxy)Phenyl)Butan-1-Amine | US1...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323466(3-Amino-1-(3-((Tetrahydro-2H-Pyran-2-Yl)Methoxy)Ph...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323467(2-(3-(Pentyloxy)Phenoxy)Ethanamine | US10188615, E...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323468(3-Amino-1-(3-(2-Methoxybenzyloxy)Phenyl)Propan-1-O...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323469(2-(3-(Cyclooctylmethoxy)Phenoxy)Ethanamine | US101...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323470(3-(3-(Cyclopentylmethoxy)Phenyl)Propan-1-Amine | U...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323471(2-(3-(Cyclopentylmethoxy)Phenoxy)Ethanamine | US10...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323472(3-Amino-1-(3-(2,6-Dichlorobenzyloxy)Phenyl)Propan-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323474(3-Amino-1-(3-(Cyclooctylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323475(3-Amino-1-(3-(Isopentyloxy)Phenyl)Propan-1-Ol | US...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323476(3-Amino-1-(3-(3-Methoxypropoxy)Phenyl)Propan-1-Ol ...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323477(3-Amino-1-(3-(4-(Benzyloxy)Butoxy)Phenyl)Propan-1-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323478(3-Amino-1-(3-(5-(Benzyloxy)Pentyloxy)Phenyl)Propan...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323479(2-(3-(Cyclohexylmethoxy)Phenylthio)Ethanamine | US...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323480(3-(3-(Cyclohexylmethoxy)Phenyl)-3-Hydroxypropanimi...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323481(3-Amino-1-(3-(3-(Benzyloxy)Propoxy)Phenyl)Propan-1...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323482((1,2-Cis)-2-((3-(3-Aminopropyl)Phenoxy)Methyl)Cycl...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323483((1,2-Trans)-2-((3-(3-Aminopropyl)Phenoxy)Methyl)Cy...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323484(2-(3-(Cyclohexylmethoxy)-5-Methylphenoxy)Ethanamin...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323485(1-(3-(3-Amino-1-Hydroxypropyl)Phenoxy)-3-Methylbut...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323486(3-Amino-1-(3-(2-Hydroxy-2-Phenylethoxy)Phenyl)Prop...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323487(1-(3-(3-Amino-1-Hydroxypropyl)Phenoxy)Pentan-2-Ol ...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323488(5-(3-(3-Amino-1-Hydroxypropyl)Phenoxy)Pentan-1-Ol ...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323490((1,2-Trans)-2-((3-((R)-3-Amino-1-Hydroxypropyl)Phe...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
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