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Found 676 Enz. Inhib. hit(s) with Target = 'N-lysine methyltransferase SMYD2'
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)
Affinity DataKi:  8nMAssay Description:Competitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using varying levels of Btn-Ahx-GSRAHSSHLKSKK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180955(CHEMBL3818617)
Affinity DataKi:  28nMAssay Description:Uncompetitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using fixed levels of Btn-Ahx-GSRAHSSHLKSKK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50396022(CHEMBL2169920)
Affinity DataKi:  300nMAssay Description:Competitive binding affinity to full length human SMYD2 amino acid 1 to 433 expressed in Escherichia coli BL21 (DE3) after 90 mins by radioactive fil...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378746(N-(1-((1-(4-chlorobenzyl)-1H-pyrazol-4-yl)methyl)a...)
Affinity DataIC50:  1.20nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283143((2R)—N-[1-{N′-cyano-N-[3-(difluorometho...)
Affinity DataIC50:  2.64nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50095537(CHEMBL3590526 | US9598381, 1a (S enantiomer))
Affinity DataIC50:  2.80nMAssay Description:Inhibition of SMYD2 (unknown origin) using biotinylated GSRAHSSHLKSKKGQSTSRH as substrate assessed as incorporation of tritium labeled methyl group f...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378802(N-(1-((1-(4-chlorobenzyl)-1H-pyrazol-4-yl)methyl)a...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human SMYD2 overexpressing human KYSE-150 cells assessed as SMYD2 assessed as reduction in BTF3 monomethylation by Western blot analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50599376(CHEMBL3819011)
Affinity DataIC50:  3nMAssay Description:Inhibition of SMYD2 (unknown origin) using 3H-SAM as substrate incubated for 1 hr by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378747(N-(1-((1-(4-chlorobenzyl)-1H-pyrazol-4-yl)methyl)a...)
Affinity DataIC50:  3.30nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378802(N-(1-((1-(4-chlorobenzyl)-1H-pyrazol-4-yl)methyl)a...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of FLAG and C-terminally Avi-tagged full length SMYD2 (unknown origin) expressed in Sf9 cells using SAM and histone H3 (1 to 29 residues) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378802(N-(1-((1-(4-chlorobenzyl)-1H-pyrazol-4-yl)methyl)a...)
Affinity DataIC50:  3.90nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283194(Rac-N-[1-(N′-cyano-N-{5-(difluoromethoxy)-2-...)
Affinity DataIC50:  5.55nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50095536(CHEMBL3590527 | US9598381, 1 (racemate))
Affinity DataIC50:  5.60nMAssay Description:Inhibition of SMYD2 (unknown origin) using biotinylated GSRAHSSHLKSKKGQSTSRH as substrate assessed as incorporation of tritium labeled methyl group f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50519299(CHEMBL4536230)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283173(N-[1-{N′-cyano-N-[2-methoxy-5-(trifluorometh...)
Affinity DataIC50:  6.65nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378750(N-(1-((1-benzyl-1H-pyrazol-4-yl)methyl)azetidin-3-...)
Affinity DataIC50:  7.80nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283196(Rac-N-[1-(N′-cyano-N-{2-[(1-methylpiperidin-...)
Affinity DataIC50:  9.09nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283172(Rac-N-[1-{N′-cyano-N-[2-methoxy-5-(trifluoro...)
Affinity DataIC50:  9.98nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378744(N-(1-((1-(4-chlorobenzyl)-1H-pyrazol-4-yl)methyl)a...)
Affinity DataIC50:  11nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50550528(CHEMBL4756148)
Affinity DataIC50:  12nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283169(Rac-N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-...)
Affinity DataIC50:  12.5nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378783(N-(1-((1-benzyl-1H-pyrazol-4-yl)methyl)azetidin-3-...)
Affinity DataIC50:  13nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283143((2R)—N-[1-{N′-cyano-N-[3-(difluorometho...)
Affinity DataIC50:  13nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283139(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)
Affinity DataIC50:  13.2nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283139(N-[1-{N′-cyano-N-[3-(difluoromethoxy)phenyl]...)
Affinity DataIC50:  13.5nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378760(1-cyclopropyl-N-(1-((1-(4-(trifluoromethyl)benzyl)...)
Affinity DataIC50:  14nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl-GSRAHSSHLKSKKGQSTSRH as substrate after 75 mi...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin) using [H3]-SAM and p53 (361 to 380 residues) as peptide substrate incubated for 1 hr by scintillation proximity ...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283132(Rac-N-[1-{N′-cyano-N-[3-(difluoromethoxy)phe...)
Affinity DataIC50:  15nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin) using [3H]-p53 (361 to 380 residues) as substrate after 1 hr in presence of [3H]-SAM by scintillation proximity ...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50075102(CHEMBL3414623)
Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin) using p53 (361 to 380) as substrate assessed as incorporation of tritium labeled methyl group from [3H]-SAM to p...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283195(Rac-N-[r-(N′-cyano-N-[2-[2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  15.8nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378810(1-cyclopropyl-N-(1-((1-(4-methylbenzyl)-1H-pyrazol...)
Affinity DataIC50:  16nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50519300(CHEMBL4520134)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378654(N-{1-[(1-benzyl-1H-pyrazol-4-yl)methyl]azetidin-3-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of FLAG and C-terminally Avi-tagged full length SMYD2 (unknown origin) expressed in Sf9 cells using SAM and histone H3 (1 to 29 residues) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378654(N-{1-[(1-benzyl-1H-pyrazol-4-yl)methyl]azetidin-3-...)
Affinity DataIC50:  16.4nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50550527(CHEMBL4754902)
Affinity DataIC50:  17nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50554178(CHEMBL4798655)
Affinity DataIC50:  17nMAssay Description:Inhibition of SMYD2 (unknown origin) transfected in human U2OS cells assessed as inhibition of methylation of monomethyl p53 peptide incubated for 24...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50550527(CHEMBL4754902)
Affinity DataIC50:  17nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50180967(CHEMBL3818487)
Affinity DataIC50:  19nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283184(N-[1-{N′-cyano-N-[3-(difluoromethoxy)-5-fluo...)
Affinity DataIC50:  19.2nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283172(Rac-N-[1-{N′-cyano-N-[2-methoxy-5-(trifluoro...)
Affinity DataIC50:  21.3nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM378768(1-cyclopropyl-N-(1-((1-(4-fluorobenzyl)-1H-pyrazol...)
Affinity DataIC50:  22nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283205(N-[3-(4-Chloro-3-methylphenyl)-1-{N′-cyano-N...)
Affinity DataIC50:  22.9nMpH: 9.0Assay Description:SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50095537(CHEMBL3590526 | US9598381, 1a (S enantiomer))
Affinity DataIC50:  23nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50519299(CHEMBL4536230)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50519305(CHEMBL4449427)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM283173(N-[1-{N′-cyano-N-[2-methoxy-5-(trifluorometh...)
Affinity DataIC50:  23.6nMAssay Description:For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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