Found 322 Enz. Inhib. hit(s) with Target = 'SRSF protein kinase 1' 
Affinity DataKi: 890nMAssay Description:Inhibition of mouse His6-tagged SRPK1 expressed in Escherichia coli(BL21)More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 2.31E+3nMAssay Description:Inhibition of SRPK1More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.884nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 1.15nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 1.91nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 2.53nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 2.61nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 2.66nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.01nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 3.18nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 3.18nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 4.75nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 5.09nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of SRPK1 (unknown origin) using SRSF1 Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH) as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.18nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 7.18nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Inhibition of SRPK1 (unknown origin) using SRSF1 Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH) as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
