Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium/hydrogen exchanger 5'
TargetSodium/hydrogen exchanger 5(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50196789(CHEMBL3892788)
Affinity DataIC50:  291nMAssay Description:Inhibition of human NHE5 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 5(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50104844(BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...)
Affinity DataIC50:  3.36E+3nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 5(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 5(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-5 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed