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Found 134 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712]'
LigandPNGBDBM577094((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50: <0.570nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577126(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  1.44nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577172(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-3,4,7,8...)
Affinity DataIC50:  2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577123(10-(4-Chloro-5-fluoro-2-methylphenyl)-8-cyclopropy...)
Affinity DataIC50:  2.45nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577128(2-Chloro-5-(8-cyclopropyl-9-oxo-6,7,8,9-tetrahydro...)
Affinity DataIC50:  2.88nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577142(10-(4-Chloro-2-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  2.88nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577143(10-(3-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...)
Affinity DataIC50:  3.16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577131(8-Cyclopropyl-10-(4-fluoro-3-methylphenyl)-7,8-dih...)
Affinity DataIC50:  3.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577130(10-(3-Chloro-4-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  3.48nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577077(10-(4-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...)
Affinity DataIC50:  4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577135(8-Cyclopropyl-10-(3,4,5-trifluorophenyl)-7,8-dihyd...)
Affinity DataIC50:  4.36nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577129(8-Cyclopropyl-10-(2,3-dihydro-1-benzofuran-5-yl)-7...)
Affinity DataIC50:  5.52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577173(10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...)
Affinity DataIC50:  5.94nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577096(8-Cyclopropyl-10-(4-methylphenyl)pyrido[2′,3...)
Affinity DataIC50:  6.59nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577141(8-Cyclopropyl-10-(2,5-difluorophenyl)-7,8-dihydrop...)
Affinity DataIC50:  6.98nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577140(8-Cyclopropyl-10-(3-fluoro-4-methoxyphenyl)-7,8-di...)
Affinity DataIC50:  7.88nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577166(4-(8-Cyclopropyl-9-oxo-8,9-dihydropyrido[2',3':4,5...)
Affinity DataIC50:  8.55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577121(9-(4-Chlorophenyl)-7-cyclopropyl-6,7-dihydro[1,3]t...)
Affinity DataIC50:  9.03nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577136(8-Cyclopropyl-10-(3-fluorophenyl)-7,8-dihydropyrid...)
Affinity DataIC50:  9.22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577144(8-Cyclopropyl-10-(4-fluoro-2-methylphenyl)-7,8-dih...)
Affinity DataIC50:  9.39nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577145(4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2'...)
Affinity DataIC50:  9.62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577152(10-(4-Chlorophenyl)-8-(5-methyl-1,2-oxazol-3-yl)-7...)
Affinity DataIC50:  10.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577127(8-Cyclopropyl-10-(3,4-dimethylphenyl)-7,8-dihydrop...)
Affinity DataIC50:  11.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577107(8-Cyclopropyl-10-(4-methylphenyl)-7,8-dihydropyrid...)
Affinity DataIC50:  11.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577171(10-(4-Chlorophenyl)-8-cyclopropyl-3,4,7,8-tetrahyd...)
Affinity DataIC50:  11.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577161(8-Cyclopropyl-10-(2,4-dimethylphenyl)-7,8-dihydrop...)
Affinity DataIC50:  13.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577091(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  13.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577120(5-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2'...)
Affinity DataIC50:  14.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577168(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)
Affinity DataIC50:  15.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577101(4-(8-Cyclopropyl-9-oxo-3,4,6,7,8,9-hexahydro-2H-py...)
Affinity DataIC50:  15.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM457828(US10738063, Example 58)
Affinity DataIC50:  16.4nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577162(8-Cyclopropyl-10-(2,4-dimethyl-phenyl)pyrido[2',3'...)
Affinity DataIC50:  16.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577079(4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2&...)
Affinity DataIC50:  17nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM577182(10-Cyclopentyl-8-cyclopropyl-7,8-dihydropyrido[2',...)
Affinity DataIC50:  18.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577109(4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2'...)
Affinity DataIC50:  20.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577133(8-Cyclopropyl-10-(2,4-difluorophenyl)-7,8-dihydrop...)
Affinity DataIC50:  21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577122(4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...)
Affinity DataIC50:  21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577095(10-(4-Chlorophenyl)-2-cyclopropyl-3,4-dihydropyraz...)
Affinity DataIC50:  23.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577163(11-(4-Chlorophenyl)-6,6a,7,8-tetrahydro-10H-azeto[...)
Affinity DataIC50:  24.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577103(10-(4-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrro...)
Affinity DataIC50:  24.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577115(8-Cyclopropyl-10-(3,5-difluoro-4-methoxyphenyl)-7,...)
Affinity DataIC50:  24.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577163(11-(4-Chlorophenyl)-6,6a,7,8-tetrahydro-10H-azeto[...)
Affinity DataIC50:  26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577093((7R)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50:  28.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM399978(US10323042, Example 57 | US10738063, Example 57)
Affinity DataIC50:  28.5nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM399927((6S)-3-(4-Chloro-2,5-difluorophenyl)-N-cyclopropyl...)
Affinity DataIC50:  31.4nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577149(8-Cyclopropyl-10-(2-fluoro-4-methoxyphenyl)-7,8-di...)
Affinity DataIC50:  35.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577160(8-Cyclopropyl-10-(furo[3,2-b]pyridin-6-yl)-7,8-dih...)
Affinity DataIC50:  37.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM399967(US10323042, Example 47 | US10738063, Example 47)
Affinity DataIC50:  45.8nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM399952(US10323042, Example 32 | US10738063, Example 32)
Affinity DataIC50:  48.2nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577170(10-(4-Chloro-3-fluorophenyl)-8-(pyrimidin-2-yl)-7,...)
Affinity DataIC50:  52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 134 total ) | Next | Last >>
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