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Found 5 Enz. Inhib. hit(s) with Target = 'Adrenocorticotropic hormone receptor'
TargetAdrenocorticotropic hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169442((1R,4S,6R)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 2 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdrenocorticotropic hormone receptor(Mus musculus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50029747((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdrenocorticotropic hormone receptor(Mus musculus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50134488((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdrenocorticotropic hormone receptor(Mus musculus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50134486((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdrenocorticotropic hormone receptor(Mus musculus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50119368((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed