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Found 27 Enz. Inhib. hit(s) with Target = 'Acyl-CoA 6-desaturase'
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257808(CHEMBL495001 | N-(2-(6-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257967(CHEMBL494748 | N-(2-(7-(4-chloro-3-(trifluoromethy...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257919(CHEMBL493960 | N-(2-(7-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257860(CHEMBL495194 | N-(2-(7-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50258014(CHEMBL494750 | N-(2-(2-(3,4-dichlorobenzylamino)-6...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257758(3-(2-(4-methoxyphenyl)-3-oxo-6-(3-(trifluoromethyl...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257757(3-(6-(3,4-dichlorobenzylamino)-2-(4-methoxyphenyl)...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50258197(CHEMBL495191 | N-(2-(6-(3,4-dichlorobenzylamino)-2...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50312701(5-methyl-3-(2-(4-(2-(trifluoromethyl)phenoxy)piper...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of delta6 desaturase in human HepG2 cells assessed as [14C]linolenic acid to [14C]eicosatetraenoic acid conversion pretreated 15 mins befo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of D6D in Sprague-Dawley rat liver microsomes using [14C]LA as substrate preincubated for 5 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50116708(CHEMBL2263368)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of D6D in Sprague-Dawley rat liver microsomes using [14C]LA as substrate preincubated for 5 mins measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50301057(2-(4-(2-(trifluoromethyl)benzoyl)piperazin-1-yl)th...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to delta-6 saturase in human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of delta-6 desaturase expressed in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Mus musculus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259087(CHEMBL467716 | benzyl 3-(3,4-dichlorobenzylcarbamo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of delta(6)-desaturase in mouse ABMC7 cells by high throughput radioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50298898(2-hydroxy-N-(2-(3-methyl-2-oxo-7-(3-(trifluorometh...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of stearoyl-CoA delta6 desaturase in rat microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Mus musculus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259175(CHEMBL444433 | N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of delta(6)-desaturase in mouse ABMC7 cells by high throughput radioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50362583(CHEMBL1938871)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human delta-6 desaturase activity in human HepG2 cells using [1-14C]-stearic acid tracerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50393165(CHEMBL2153600)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of rat delta-6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50362592(CHEMBL1938870)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of human delta6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50393166(CHEMBL2153601)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of human delta6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50393165(CHEMBL2153600)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of human delta6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50393164(CHEMBL2153599)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of human delta6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50393164(CHEMBL2153599)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of rat delta-6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50305768(2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piper...)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of rat delta-6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50362592(CHEMBL1938870)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of rat delta-6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50393166(CHEMBL2153601)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of rat delta-6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50305768(2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piper...)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of human delta6 desaturase activity expressed in human HEpG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed