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Found 57 Enz. Inhib. hit(s) with Target = 'Guanine nucleotide-binding protein G(o) subunit alpha'
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468898(CHEMBL4278309)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468900(CHEMBL4282827)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468904(CHEMBL4173778)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468897(CHEMBL4286220)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468899(CHEMBL4286619)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468901(CHEMBL4294526)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468903(CHEMBL4279374)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM47776(3-chloranyl-N-(3-morpholin-4-ylpropyl)-6-nitro-1-b...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67699((3-chloranyl-6-nitro-1-benzothiophen-2-yl)-piperaz...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67700(3-chloranyl-6-nitro-1-benzothiophene-2-carboxamide...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67701(3-chloranyl-6-methyl-N-(3-morpholin-4-ylpropyl)-1-...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67702(3-chloranyl-N-(3-imidazol-1-ylpropyl)-6-nitro-1-be...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM47776(3-chloranyl-N-(3-morpholin-4-ylpropyl)-6-nitro-1-b...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67699((3-chloranyl-6-nitro-1-benzothiophen-2-yl)-piperaz...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67700(3-chloranyl-6-nitro-1-benzothiophene-2-carboxamide...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67701(3-chloranyl-6-methyl-N-(3-morpholin-4-ylpropyl)-1-...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67702(3-chloranyl-N-(3-imidazol-1-ylpropyl)-6-nitro-1-be...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM47776(3-chloranyl-N-(3-morpholin-4-ylpropyl)-6-nitro-1-b...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM50174642(1-{4-[2-(1-Methyl-piperidin-4-yl)-ethyl]-piperidin...)
Affinity DataEC50:  1.25E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174649(1-[4,4']Bipiperidinyl-1-yl-heptadecan-1-one; hydro...)
Affinity DataEC50:  2.26E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174652(1'-Methyl-1-tridecyl-[4,4']bipiperidinyl; dihydroc...)
Affinity DataEC50:  1.93E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174645(1-(4-Amino-piperazin-1-yl)-pentadecan-1-one; dihyd...)
Affinity DataEC50:  3.74E+5nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174651(1-Heptadecyl-[4,4']bipiperidinyl; dihydrochloride ...)
Affinity DataEC50:  1.34E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174646(CHEMBL536278 | Pentadecyl-piperidin-4-yl-amine; di...)
Affinity DataEC50:  1.33E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174643(1-Pentadecyl-4-(2-piperidin-4-yl-ethyl)-piperidine...)
Affinity DataEC50:  1.05E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174655(1-[4-(2-Piperidin-4-yl-ethyl)-piperidin-1-yl]-pent...)
Affinity DataEC50:  6.10E+3nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174657(1-(4-Amino-piperidin-1-yl)-pentadecan-1-one; hydro...)
Affinity DataEC50:  2.58E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174650(CHEMBL535154 | Pentadecanoic acid piperazin-1-ylam...)
Affinity DataEC50:  2.34E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174656(4-Pentadecyl-piperazin-1-ylamine; trihydrochloride...)
Affinity DataEC50:  3.70E+3nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174659(CHEMBL536730 | Pentadecanoic acid piperidin-4-ylam...)
Affinity DataEC50:  2.27E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174644(1-(1'-Methyl-[4,4']bipiperidinyl-1-yl)-heptadecan-...)
Affinity DataEC50:  2.14E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174658(1-(2-Formylamino-ethyl)-piperidine-4-carboxylic ac...)
Affinity DataEC50:  5.50E+3nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174663(1-(1'-Methyl-[4,4']bipiperidinyl-1-yl)-pentadecan-...)
Affinity DataEC50:  3.49E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174661(CHEMBL535827 | Pentadecyl-piperidin-4-ylmethyl-ami...)
Affinity DataEC50:  1.24E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174666((1-Pentadecyl-piperidin-4-yl)-piperidin-4-yl-amine...)
Affinity DataEC50:  1.35E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174665(CHEMBL541892 | [1-(2-Amino-ethyl)-piperidin-4-ylme...)
Affinity DataEC50:  2.43E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174647(1-[4,4']Bipiperidinyl-1-yl-pentadecan-1-one; hydro...)
Affinity DataEC50:  5.60E+3nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174667(CHEMBL536962 | Piperidin-4-yl-tridecyl-amine; dihy...)
Affinity DataEC50:  2.55E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174641(2,6-Diamino-hexanoic acid dodecylamide | CHEMBL197...)
Affinity DataEC50:  2.88E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174668(1-Methyl-1-pentadecyl-[4,4']bipiperidinyl-1-ium; c...)
Affinity DataEC50:  1.01E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174669(CHEMBL559378 | Pentadecyl-piperazin-1-yl-amine; tr...)
Affinity DataEC50:  6.10E+3nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174662(1-Tridecyl-[4,4']bipiperidinyl; dihydrochloride | ...)
Affinity DataEC50:  2.71E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174670(1-Pentadecyl-[4,4']bipiperidinyl; dihydrochloride ...)
Affinity DataEC50:  6.20E+3nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174648(CHEMBL536499 | Piperidine-4-carboxylic acid pentad...)
Affinity DataEC50:  8.20E+3nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174653(1-[4,4']Bipiperidinyl-1-yl-tridecan-1-one; hydroch...)
Affinity DataEC50:  1.81E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174660(1-(2-Amino-ethyl)-piperidine-4-carboxylic acid pen...)
Affinity DataEC50:  1.69E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50174664(1-Pentadecyl-piperidin-4-ylamine; dihydrochloride ...)
Affinity DataEC50:  2.30E+4nMAssay Description:Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha o1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM67702(3-chloranyl-N-(3-imidazol-1-ylpropyl)-6-nitro-1-be...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM67701(3-chloranyl-6-methyl-N-(3-morpholin-4-ylpropyl)-1-...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
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