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Found 1135 Enz. Inhib. hit(s) with Target = 'Lysyl oxidase homolog 2'
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataKi:  83nMAssay Description:Time-dependent inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as apparent inh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505633(CHEMBL4448713)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Mus musculus)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant mouse C-terminal His-tagged LOLX2 (26-776 residues) expressed in mouse myeloma cells using putrescine as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Rattus norvegicus)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant rat LOLX2 using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50:  9nMAssay Description:Inhibition of LOXL2 in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human LOXL2 assessed as inhibition of collagen cross linking compound replenishment for 5 days and measured on day 7 by UPL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505640(CHEMBL4556859)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as inhibition of collagen oxid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505653(CHEMBL4458907)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505647(CHEMBL4531065)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505657(CHEMBL4467234)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505658(CHEMBL4581458)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505643(CHEMBL4582216)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526723(CHEMBL4515085 | US10807974, Example 121 | US109950...)
Affinity DataIC50:  28nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526723(CHEMBL4515085 | US10807974, Example 121 | US109950...)
Affinity DataIC50:  28nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526723(CHEMBL4515085 | US10807974, Example 121 | US109950...)
Affinity DataIC50:  28nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266796(CHEMBL4068580)
Affinity DataIC50:  34nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266838(CHEMBL4084982)
Affinity DataIC50:  35nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266824(CHEMBL4082808)
Affinity DataIC50:  43nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469087(US10807974, Example 106 | US10995088, Example 106 ...)
Affinity DataIC50:  45nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469087(US10807974, Example 106 | US10995088, Example 106 ...)
Affinity DataIC50:  45nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469087(US10807974, Example 106 | US10995088, Example 106 ...)
Affinity DataIC50:  45nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266783(CHEMBL4086010)
Affinity DataIC50:  50nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505645(CHEMBL4550754)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266784(CHEMBL4103928)
Affinity DataIC50:  53nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469088(US10807974, Example 107 | US10995088, Example 107 ...)
Affinity DataIC50:  56nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469029(US10807974, Example 14 | US10807974, Example 42 | ...)
Affinity DataIC50:  56nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266789(CHEMBL4088453)
Affinity DataIC50:  56nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469029(US10807974, Example 14 | US10807974, Example 42 | ...)
Affinity DataIC50:  56nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469088(US10807974, Example 107 | US10995088, Example 107 ...)
Affinity DataIC50:  56nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469088(US10807974, Example 107 | US10995088, Example 107 ...)
Affinity DataIC50:  56nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469029(US10807974, Example 14 | US10807974, Example 42 | ...)
Affinity DataIC50:  56nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266823(CHEMBL4097435)
Affinity DataIC50:  58nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526725(CHEMBL4450748 | US10807974, Example 122 | US109950...)
Affinity DataIC50:  58nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526725(CHEMBL4450748 | US10807974, Example 122 | US109950...)
Affinity DataIC50:  58nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526725(CHEMBL4450748 | US10807974, Example 122 | US109950...)
Affinity DataIC50:  58nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526740(CHEMBL4447452 | US10807974, Example 108 | US109950...)
Affinity DataIC50:  60nMAssay Description:10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526740(CHEMBL4447452 | US10807974, Example 108 | US109950...)
Affinity DataIC50:  60nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50526740(CHEMBL4447452 | US10807974, Example 108 | US109950...)
Affinity DataIC50:  60nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266788(CHEMBL4067192)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266788(CHEMBL4067192)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266811(CHEMBL4059919)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266811(CHEMBL4059919)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50266838(CHEMBL4084982)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505661(CHEMBL4574820)
Affinity DataIC50:  63nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469139(US10807974, Example 158 | US10995088, Example 158 ...)
Affinity DataIC50:  64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM469139(US10807974, Example 158 | US10995088, Example 158 ...)
Affinity DataIC50:  64nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 1 hour at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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