Affinity DataKi: 740nMAssay Description:Competitive inhibition of human MDH1 expressed in Escherichia coli using oxaloacetic acid as substrate in presence of NADH after 30 mins by double re...More data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetMalate dehydrogenase, cytoplasmic(Sus scrofa (pig))
University Of Rochester Medical Center
Curated by ChEMBL
University Of Rochester Medical Center
Curated by ChEMBL
Affinity DataKi: 3.63E+4nMAssay Description:In vitro inhibitory activity against pig heart cytoplasmic malate dehydrogenase (MDH)More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MDH1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Ability to inhibit mitochondrial malate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair