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Found 73 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 9'
TargetTyrosine-protein phosphatase non-receptor type 9 [277-582](Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM231167(US9340574, 7)
Affinity DataKi:  34nM IC50:  75nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 9 [277-582](Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM231166(US9340574, 5)
Affinity DataIC50:  270nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50531902(CHEMBL4569405)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant PTP-MEG2 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9 [277-582](Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM231165(US9340574, 3)
Affinity DataIC50:  900nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425815(CHEMBL2316908)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425808(CHEMBL2316906)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50531903(CHEMBL4530344)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant PTP-MEG2 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425818(CHEMBL2316905)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425806(CHEMBL2316907)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425807(CHEMBL2316902)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425816(CHEMBL2316910)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50531901(CHEMBL4540813)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425809(CHEMBL2316896)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425810(CHEMBL2316895)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425811(CHEMBL2316894)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425819(CHEMBL2316904)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425814(CHEMBL2311593)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50031906(CHEMBL3360905)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425813(CHEMBL2316897)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50524069(CHEMBL4454177)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50524067(CHEMBL4514865)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50524068(CHEMBL4453288)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant human MEG2 expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425820(CHEMBL2316903)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425817(CHEMBL2316909)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50335895(6-hydroxy-3-(1-(4-(naphthalen-1-ylamino)-4-oxobuty...)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of PTP-Meg2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50031908(CHEMBL3360906)
Affinity DataIC50:  3.75E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50343147(CHEMBL1773180 | N1-(furan-2-ylmethyl)-N2-(1-(4-(4-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50343148(CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112357(CHEMBL3609375)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112358(CHEMBL3609374)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50343142(CHEMBL1773168 | N-(4-butylphenyl)-2-oxo-1,2-dihydr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM53072((5Z)-3-allyl-5-(3-ethyl-1,3-benzothiazol-2-ylidene...)
Affinity DataIC50:  5.94E+4nMAssay Description:Inhibition of GST-tagged MEG2 (unknown origin) using phospho-EGFR Asp-Ala-Asp-Glu-Tyr[PO3H2]-Leu-Ile-Pro-Gln-Gln-Gly as substrate preincubated for 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50343530(5,7-dichloro-4-((3-(4-methoxyphenylthio)benzyl)(me...)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50363857(CHEMBL1946248)
Affinity DataIC50:  6.86E+4nMAssay Description:Inhibition of human PTP-MEG2 using p-nitrophenol phosphate as substrate incubated for 35 mins prior to substrate addition measured after 30 mins by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50498446(CHEMBL3596431)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of human PTP-Meg2 using pNPP substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50031910(CHEMBL3360908)
Affinity DataIC50:  7.85E+4nMAssay Description:Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425823(CHEMBL2316901)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425821(CHEMBL2316900)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425822(CHEMBL2316899)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558485(CHEMBL4800195)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558461(CHEMBL4760367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50425812(CHEMBL2316898)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50363855(CHEMBL1946246)
Affinity DataIC50:  1.46E+5nMAssay Description:Inhibition of human PTP-MEG2 using p-nitrophenol phosphate as substrate incubated for 35 mins prior to substrate addition measured after 30 mins by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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