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Found 105 Enz. Inhib. hit(s) with Target = 'Transketolase'
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263817(5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant transketolase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230586(CHEMBL252845 | N-((2-amino-6-methylpyridin-3-yl)me...)
Affinity DataEC50:  15nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230587(CHEMBL440237 | N-(2-amino-6-methyl-pyridin-3-ylmet...)
Affinity DataEC50:  12nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230588(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  28nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230589(3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)...)
Affinity DataEC50:  110nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230590(CHEMBL402594 | N-(2-amino-6-chloro-pyridin-3-ylmet...)
Affinity DataEC50:  8nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230591(3-(acetylthio)-4-(N-((2-amino-6-methylpyridin-3-yl...)
Affinity DataEC50:  8nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230592(CHEMBL251889 | N-(2-amino-pyridin-3-ylmethyl)-N-{2...)
Affinity DataEC50:  479nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230593(3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  9nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230595(CHEMBL251888 | N-{2-[2-[acetyl-(2-amino-6-methyl-p...)
Affinity DataEC50:  32nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230594((4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formam...)
Affinity DataEC50:  116nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230596(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  9.54E+3nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230597(4-(N-((2-amino-6-methylpyridin-3-yl)methyl)formami...)
Affinity DataEC50:  28nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230598(CHEMBL253045 | N-((2-amino-6-methylpyridin-3-yl)me...)
Affinity DataEC50:  13nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230599(3-(2-(4-(N-((2-amino-6-methylpyridin-3-yl)methyl)f...)
Affinity DataEC50:  52nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230600(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  18nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230601(CHEMBL401964 | N-((2-amino-6-methylpyridin-3-yl)me...)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230602(CHEMBL252085 | N-(2-amino-6-methyl-pyridin-3-ylmet...)
Affinity DataEC50:  1.02E+5nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230600(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataEC50:  26nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373716(CHEMBL403212)
Affinity DataKd:  75nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373717(CHEMBL255541)
Affinity DataKd:  40nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373718(CHEMBL402065)
Affinity DataKd:  140nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373719(CHEMBL256267)
Affinity DataKd:  220nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373720(CHEMBL271044)
Affinity DataKd:  34nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373721(CHEMBL270384)
Affinity DataKd:  109nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373722(CHEMBL256831)
Affinity DataKd:  23nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373716(CHEMBL403212)
Affinity DataEC50:  21nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373723(CHEMBL271886)
Affinity DataEC50:  2.50E+4nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373724(CHEMBL270632)
Affinity DataEC50:  490nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373725(CHEMBL258077)
Affinity DataEC50:  50nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230589(3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)...)
Affinity DataEC50:  110nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373727(CHEMBL257929)
Affinity DataEC50:  470nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373728(CHEMBL429246)
Affinity DataEC50:  360nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373729(CHEMBL401817)
Affinity DataKd:  22nMAssay Description:Binding affinity to apo-transketolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230600(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataKd:  33nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230596(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataKd:  29nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230588(3-(2-amino-6-methyl-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataKd:  25nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373732(CHEMBL255339)
Affinity DataKd:  120nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373724(CHEMBL270632)
Affinity DataKd:  36nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373733(CHEMBL402566)
Affinity DataKd:  25nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373734(CHEMBL255340)
Affinity DataKd:  27nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373725(CHEMBL258077)
Affinity DataKd:  28nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373725(CHEMBL258077)
Affinity DataKd:  53nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230589(3-(2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)...)
Affinity DataKd:  36nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373735(CHEMBL255603)
Affinity DataKd:  7nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373736(CHEMBL271521)
Affinity DataKd:  64nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373727(CHEMBL257929)
Affinity DataKd:  310nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50230593(3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydro...)
Affinity DataKd:  46nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373738(CHEMBL256627)
Affinity DataKd:  10nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50373728(CHEMBL429246)
Affinity DataKd:  57nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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