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Found 5 Enz. Inhib. hit(s) with Target = 'Type IV secretion-like conjugative transfer relaxase protein TraI'
TargetType IV secretion-like conjugative transfer relaxase protein TraI(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50478336(Imidobisphosphate | Imidodiphosphate)
Affinity DataKi:  2nMAssay Description:Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType IV secretion-like conjugative transfer relaxase protein TraI(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50478336(Imidobisphosphate | Imidodiphosphate)
Affinity DataKi:  2.70nMAssay Description:Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by uncompetitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType IV secretion-like conjugative transfer relaxase protein TraI(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50216172((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)
Affinity DataKi:  3nMAssay Description:Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType IV secretion-like conjugative transfer relaxase protein TraI(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50115102((1-Hydroxy-1-phosphono-ethyl)-phosphonic acid | CH...)
Affinity DataKi:  3nMAssay Description:Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType IV secretion-like conjugative transfer relaxase protein TraI(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50162816(CHEMBL180570 | Medronic acid | Methylene diphsphon...)
Affinity DataKi:  3nMAssay Description:Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed