Affinity DataKi: 250nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Uncompetitive inhibition of recombinant human tyrosinase expressed in baculovirus infected sf9 cells using L-DOPA as substrate by double-reciprocal p...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of human tyrosinase expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 3.70E+3nMAssay Description:Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+4nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+4nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+4nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 6.40E+4nMAssay Description:Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+4nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.28E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.28E+5nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
Affinity DataKi: 1.28E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.40E+5nMAssay Description:Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+5nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+5nMAssay Description:Mixed inhibition of recombinant human tyrosinase expressed in baculovirus infected sf9 cells using L-DOPA as substrate by double-reciprocal plot anal...More data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.50E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 240 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.80E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.90E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 3.10E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 60 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataKi: 5.50E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-dihydroxyphenylalanine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for inhibition of tyrosinase enzyme.More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
National Institute Of Advanced Industrial Science And Technology
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human tyrosinase expressed in HEK293 cells using L-tyrosine and DOPA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate preincubated for 5 mins followed by substrate additionMore data for this Ligand-Target Pair