Compile Data Set for Download or QSAR
maximum 50k data
Found 419 Enz. Inhib. hit(s) with Target = 'Large T antigen'
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533446(CHEMBL4460953)
Affinity DataIC50:  600nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32189(8-amino-7-hydroxy-4-methyl-1-benzopyran-2-one | 8-...)
Affinity DataIC50:  770nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533445(CHEMBL4531456)
Affinity DataIC50:  900nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533444(CHEMBL4519588)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60400(1-[4-[4-[(5-methyl-2-thienyl)methylamino]phenyl]pi...)
Affinity DataIC50:  3.48E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60351(MLS000070198 | SMR000011058 | cid_654792 | dibenzo...)
Affinity DataIC50:  3.50E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50309563(2-(2-(3,4-dihydroxyphenyl)-2-oxoethylthio)-4-(meth...)
Affinity DataIC50:  3.71E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM52079((5,5-diketo-6H-benzo[c][1,2]benzothiazin-9-yl)amin...)
Affinity DataIC50:  3.99E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60399(4-[3-(2,3-dihydro-1,4-benzodioxin-6-ylimino)-1,7-d...)
Affinity DataIC50:  4.14E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM38939((4E)-3-hydroxy-4-[[(4-methyl-2-methylimino-1,3-thi...)
Affinity DataIC50:  4.27E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533442(CHEMBL4438480)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60403(1-phenyl-4-pyrazolol | 1-phenylpyrazol-4-ol | MLS0...)
Affinity DataIC50:  4.71E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM40577(4-(4-Pyrrolidin-1-yl-quinazolin-2-ylamino)-phenol ...)
Affinity DataIC50:  4.72E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60363((4E)-4-[[(5-amino-1-tetrazolyl)amino]methylidene]-...)
Affinity DataIC50:  4.83E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60389(2-methoxy-4-(2-methyl-1,3-thiazol-4-yl)phenol | 2-...)
Affinity DataIC50:  4.90E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533450(CHEMBL4517025)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533460(CHEMBL4537059)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49291(MLS000061602 | N-[4-(diethylamino)phenyl]-2-furami...)
Affinity DataIC50:  5.01E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60350(3-Methyl-5-[(4-morpholin-4-yl-phenylamino)-methyl]...)
Affinity DataIC50:  5.01E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM58960((4E)-2-methoxy-4-(3-phenylimino-1,7-dihydroimidazo...)
Affinity DataIC50:  5.05E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39017((E)-3-[4-(dimethylamino)anilino]-1-phenyl-2-propen...)
Affinity DataIC50:  5.19E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60382(3-[4-(4-hydroxyphenyl)-1-piperazinyl]-1-(2-thienyl...)
Affinity DataIC50:  5.41E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533428(CHEMBL4521406)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60381(2-[(4-hydroxyanilino)methylene]-5,5-dimethyl-cyclo...)
Affinity DataIC50:  5.53E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60349(4-[4-[(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)-pyridi...)
Affinity DataIC50:  5.61E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533437(CHEMBL4452337)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60379(MLS000093093 | N-[4-(dimethylamino)phenyl]-2-[(4-k...)
Affinity DataIC50:  5.87E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60355(2-ACETAMIDOPHENOL | 2-hydroxyacetanilide | MLS0000...)
Affinity DataIC50:  6.20E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60343(MLS000035128 | N-[9-[2-[4-(dimethylamino)anilino]-...)
Affinity DataIC50:  6.24E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533459(CHEMBL4474704)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60383((2E)-2-[(4-hydroxyanilino)methylene]cyclohexanone ...)
Affinity DataIC50:  6.66E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60395(4-(3-fluoranyl-4-oxidanyl-phenyl)benzoic acid | 4-...)
Affinity DataIC50:  6.76E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60374(MLS000047422 | N-[4-(dimethylamino)phenyl]-2-[4-(2...)
Affinity DataIC50:  7.19E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Affinity DataIC50:  7.30E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60397(MLS000115777 | N-(4-hydroxyphenyl)-8-quinolinesulf...)
Affinity DataIC50:  7.36E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60385(MLS000051916 | N-(4-anilinophenyl)-4-morpholinecar...)
Affinity DataIC50:  7.43E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM51541(2-(4-Amino-phenyl)-4-chloro-3H-benzoimidazol-5-yla...)
Affinity DataIC50:  7.64E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM42946((6-morpholino-1,3-benzothiazol-2-yl)amine | 6-(4-m...)
Affinity DataIC50:  7.66E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60369((2Z)-2-(1H-benzimidazol-2-yl)-2-(1-methyl-2-pyridi...)
Affinity DataIC50:  7.70E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60371(MLS000098716 | N-(6-amino-1-benzyl-2,4-diketo-pyri...)
Affinity DataIC50:  7.74E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM34278(1-(3,4-dihydroxyphenyl)-2-[[4-ethyl-5-(2-methoxyph...)
Affinity DataIC50:  7.83E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM38617(MLS000092916 | N-[2-(diethylamino)ethyl]-5-(4-keto...)
Affinity DataIC50:  8.17E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49221(4-[[(4-methyl-2-methylimino-1,3-thiazol-3-yl)amino...)
Affinity DataIC50:  8.35E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60386(2-(3-amino-5-chloro-4-hydroxy-benzyl)isoindoline-1...)
Affinity DataIC50:  8.42E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60384((4-acetamidophenyl) 2-(1,3-dioxoisoindol-2-yl)-4-m...)
Affinity DataIC50:  8.46E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33061(4-N,4-N-dimethyl-1-N-(4-pyridin-3-yl-1,3-thiazol-2...)
Affinity DataIC50:  8.54E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533440(CHEMBL4470227)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533455(CHEMBL4562725)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(JC polyomavirus)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533427(CHEMBL4475150)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31758(8-methyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quin...)
Affinity DataIC50:  9.10E+3nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
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