Compile Data Set for Download or QSAR
maximum 50k data
Found 526 Enz. Inhib. hit(s) with Target = 'Methionine--tRNA ligase'
TargetMethionine--tRNA ligase(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Replidyne

Curated by ChEMBL
LigandPNGBDBM50333116(2-(3-((4-bromo-5-(1-fluorovinyl)-3-methylthiophen-...)
Affinity DataKi:  225nMAssay Description:Inhibition of Haemophilus influenzae MetRSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50112575(2-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-yl...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory concentration against Methionyl-tRNA synthetase in a pyrophosphate exchange assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50222700(CHEMBL161864)
Affinity DataIC50: <3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50222704(CHEMBL345835)
Affinity DataIC50: <3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124821(2-[3-(3,5-Dichloro-benzylamino)-propylamino]-1H-qu...)
Affinity DataIC50:  3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50222702(CHEMBL161347)
Affinity DataIC50: <3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50222705(CHEMBL161312)
Affinity DataIC50: <3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50222701(CHEMBL158051)
Affinity DataIC50: <3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50222699(CHEMBL161300)
Affinity DataIC50: <3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50222703(CHEMBL160841)
Affinity DataIC50: <3nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124843(2-[3-(3-Bromo-2-ethoxy-5-methoxy-benzylamino)-prop...)
Affinity DataIC50:  3.10nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124811(2-[3-(3-Bromo-5-iodo-benzylamino)-propylamino]-1H-...)
Affinity DataIC50:  3.20nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124826(2-[3-(2-Ethoxy-5-iodo-3-methyl-benzylamino)-propyl...)
Affinity DataIC50:  3.20nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149651(2-[3-(3-Bromo-2-ethoxy-5-methoxy-benzylamino)-prop...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124808(2-[3-(2-Ethoxy-3-iodo-5-methoxy-benzylamino)-propy...)
Affinity DataIC50:  3.30nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124846(2-[3-(5,7-Dichloro-1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataIC50:  3.80nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149623(CHEMBL424799 | N-(1H-Benzoimidazol-2-yl)-N''-(3-br...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149650(2-[3-(3,5-Dibromo-benzylamino)-propylamino]-1H-thi...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124851(4-Ethoxy-3-methyl-5-{[3-(4-oxo-1,4-dihydro-quinoli...)
Affinity DataIC50:  3.90nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149646(5-[3-(3,5-Dibromo-benzylamino)-propylamino]-4H-thi...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124803(5-Bromo-2-ethoxy-3-{[3-(4-oxo-1,4-dihydro-quinolin...)
Affinity DataIC50:  4nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124825(2-[3-(2-Ethoxy-3-hydroxymethyl-5-iodo-benzylamino)...)
Affinity DataIC50:  4.10nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124854(2-[3-(3-Chloro-2-ethoxy-5-methoxy-benzylamino)-pro...)
Affinity DataIC50:  4.30nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124835(2-[3-(6-Bromo-8-ethyl-1,2,3,4-tetrahydro-quinolin-...)
Affinity DataIC50:  4.30nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124817(2-[3-(3,5-Dibromo-2-ethoxy-benzylamino)-propylamin...)
Affinity DataIC50:  4.40nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124824(3-Bromo-4-ethoxy-5-{[3-(4-oxo-1,4-dihydro-quinolin...)
Affinity DataIC50:  4.60nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124813(2-[3-(3-Bromo-2-ethoxy-5-methylsulfanyl-benzylamin...)
Affinity DataIC50:  4.70nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149649(2-[3-(3,5-Dibromo-2-ethoxy-benzylamino)-propylamin...)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124800(2-[3-(3-Bromo-2-ethoxy-5-methyl-benzylamino)-propy...)
Affinity DataIC50:  4.90nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149630(CHEMBL182960 | N-(3,5-Dibromo-benzyl)-N''-(1H-imid...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124801(2-[3-(4,6-Dichloro-indan-1-ylamino)-propylamino]-1...)
Affinity DataIC50:  5.10nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124857(2-[3-(2-Ethoxy-3-methyl-5-methylsulfanyl-benzylami...)
Affinity DataIC50:  5.10nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124850(2-[3-(5-Bromo-2-ethoxy-3-methyl-benzylamino)-propy...)
Affinity DataIC50:  5.70nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124819(2-[3-(5-Bromo-2-ethoxy-3-iodo-benzylamino)-propyla...)
Affinity DataIC50:  5.90nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124852(2-[3-(5,7-Dichloro-2,3-dihydro-benzofuran-3-ylamin...)
Affinity DataIC50:  6nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149643(6-[3-(3,5-Dibromo-benzylamino)-propylamino]-7H-thi...)
Affinity DataIC50:  6.20nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50409933(CHEMBL2096779)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124827(2-[3-(3,5-Diiodo-benzylamino)-propylamino]-1H-quin...)
Affinity DataIC50:  6.40nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124858(2-[3-(2-Ethoxy-3-methyl-5-trifluoromethyl-benzylam...)
Affinity DataIC50:  6.80nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124810(2-[3-(5-Chloro-2-ethoxy-3-methyl-benzylamino)-prop...)
Affinity DataIC50:  6.80nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50222901(CHEMBL1163059)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against Escherichia coli Methionyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149648(2-[3-(3-Bromo-2-ethoxy-5-methoxy-benzylamino)-prop...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124844(2-[3-(2-Ethoxy-3-iodo-5-methyl-benzylamino)-propyl...)
Affinity DataIC50:  7.20nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124830(2-[3-(2-Allyloxy-3,5-dichloro-benzylamino)-propyla...)
Affinity DataIC50:  7.20nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124802(2-(3-(6,8-dibromo-3,4-dihydro-2H-chromen-4-ylamino...)
Affinity DataIC50:  7.80nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124848(2-[3-(8-Bromo-6-methyl-1,2,3,4-tetrahydro-quinolin...)
Affinity DataIC50:  8nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50112575(2-[3-(6,8-Dibromo-1,2,3,4-tetrahydro-quinolin-4-yl...)
Affinity DataIC50:  8nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149635(2-[3-(3,5-Dibromo-benzylamino)-propylamino]-1H-qui...)
Affinity DataIC50:  8.10nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Staphylococcus aureus (strain MW2))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149637(2-[3-(6-Bromo-8-chloro-1,2,3,4-tetrahydro-quinolin...)
Affinity DataIC50:  8.20nMAssay Description:Inhibitory concentration against Staphylococcus aureus methionyl tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50124798(2-[3-(3-Bromo-2-ethoxy-5-iodo-benzylamino)-propyla...)
Affinity DataIC50:  8.80nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS(methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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