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Found 39 Enz. Inhib. hit(s) with Target = 'Receptor activity-modifying protein 1'
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391716(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 1 | ...)
Affinity DataKi:  0.0200nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391716(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 1 | ...)
Affinity DataKi:  0.0200nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391727(N-[(2R)-1-({(2S)-3-{1-[2- | US10300056, Example 12...)
Affinity DataKi:  0.0250nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391727(N-[(2R)-1-({(2S)-3-{1-[2- | US10300056, Example 12...)
Affinity DataKi:  0.0250nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391726(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 11 |...)
Affinity DataKi:  0.0320nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391726(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 11 |...)
Affinity DataKi:  0.0320nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391722(N-[(2R)-1-({(2S)-3-(1- | US10300056, Example 7 | U...)
Affinity DataKi:  0.0400nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391723(3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 8...)
Affinity DataKi:  0.0400nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391723(3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 8...)
Affinity DataKi:  0.0400nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391719(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 4 | ...)
Affinity DataKi:  0.0400nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391722(N-[(2R)-1-({(2S)-3-(1- | US10300056, Example 7 | U...)
Affinity DataKi:  0.0400nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391719(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 4 | ...)
Affinity DataKi:  0.0400nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391725(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 10 |...)
Affinity DataKi:  0.0630nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391720(3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 5...)
Affinity DataKi:  0.0630nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391725(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 10 |...)
Affinity DataKi:  0.0630nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391720(3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 5...)
Affinity DataKi:  0.0630nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85836([N-benzol]h alpha-CGRP8-37)
Affinity DataKi:  0.0720nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391729(3,5-dibromo-Nalpha-[(2'-oxo- | US10300056, Example...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391718(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 3 | ...)
Affinity DataKi:  0.0790nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391724(3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 9...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391729(3,5-dibromo-Nalpha-[(2'-oxo- | US10300056, Example...)
Affinity DataKi:  0.0790nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391724(3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 9...)
Affinity DataKi:  0.0790nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391718(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 3 | ...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85837(h alpha-CGRP)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391721(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 6 | ...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391728(3-(4-{(2S)-2-{[(2R)-3-(7- | US10300056, Example 13...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391717(US10300056, Example 2 | US10888561, Example 2 | te...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391717(US10300056, Example 2 | US10888561, Example 2 | te...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391728(3-(4-{(2S)-2-{[(2R)-3-(7- | US10300056, Example 13...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM391721(N-[(2R)-3-(7-methyl-1H- | US10300056, Example 6 | ...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85840([N-acetyl]h alpha-CGRP8-37)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85834([Pro14]h alpha-CGRP)
Affinity DataKi:  5.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM50000743(CHEMBL525571 | [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Se...)
Affinity DataKi:  5.70nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85843([D-Pen2,7]h alpha-CGRP)
Affinity DataKi:  15.2nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85841(Adrenomedullin)
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85835([Cys(ACM)2,7]h alpha-CGRP)
Affinity DataKi:  32nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85838([Cha37]h alpha-CGRP8-37)
Affinity DataKi:  37.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85839([Pro34,Phe35]h alpha-CGRP27-37)
Affinity DataKi:  118nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor activity-modifying protein 1(PIG)
Creighton University

Curated by PDSP Ki Database
LigandPNGBDBM85842([Ala37]h alpha-CGRP8-37)
Affinity DataKi:  1.02E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed