Affinity DataKi: 1nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of catalytic activity of mouse COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid sci...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of catalytic activity of rat COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.2nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.6nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 16.6nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant COMT by microplate screening assayMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Competitive mode of inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Competitive mode of inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 6.60E+3nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 7.90E+3nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+4nMAssay Description:Compound was evaluated for reversible inhibition of Catechol O-methyltransferase with variable AdoMet and saturating catechol as substrate (mixed inh...More data for this Ligand-Target Pair
Affinity DataKi: 1.72E+4nMAssay Description:Compound was evaluated for reversible inhibition of Catechol O-methyltransferase with saturating AdoMet and variable catechol as substrate (noncompet...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 2.67E+4nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+4nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+4nMAssay Description:Inhibition of catalytic activity of mouse COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid sci...More data for this Ligand-Target Pair
Affinity DataKi: 1.36E+5nMAssay Description:In vitro inhibitory activity against Catechol-O-methyltransferase from porcine liver; Uncompetitive mode of inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 1.58E+5nMAssay Description:Inhibition of catalytic activity of rat COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid scint...More data for this Ligand-Target Pair
Affinity DataKi: 2.51E+5nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 3.28E+5nMAssay Description:Kinetic constants for the inactivation of Catechol O-methyltransferase by the compoundMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+5nMAssay Description:Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+5nMAssay Description:Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.14E+6nMAssay Description:Kinetic constants for the inactivation of Catechol O-methyltransferase by the compoundMore data for this Ligand-Target Pair
Affinity DataKi: 3.46E+6nMAssay Description:Kinetic constants for the inactivation of Catechol O-methyltransferase by the compoundMore data for this Ligand-Target Pair
Affinity DataKi: >5.40E+6nMAssay Description:Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+6nMAssay Description:Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.26E+6nMAssay Description:Kinetic constants for the inactivation of Catechol O-methyltransferase by the compoundMore data for this Ligand-Target Pair
Affinity DataKi: 1.52E+7nMAssay Description:Kinetic constants for the inactivation of Catechol O-methyltransferase by the compoundMore data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of MB-COMT in Wistar rat brain assessed as metanephrine formation preincubated for 20 mins followed by addition of adrenaline as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMAssay Description:Inhibition of MB-COMT in Wistar rat brain assessed as metanephrine formation preincubated for 20 mins followed by addition of adrenaline as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 0.912nMAssay Description:Inhibition of MB-COMT in Wistar rat brain assessed as metanephrine formation preincubated for 20 mins followed by addition of adrenaline as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Affinity DataIC50: >1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MB-COMT in Wistar rat brain assessed as metanephrine formation preincubated for 20 mins followed by addition of adrenaline as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of MB-COMT in Wistar rat brain assessed as metanephrine formation preincubated for 20 mins followed by addition of adrenaline as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of MB-COMT in Wistar rat brain assessed as metanephrine formation preincubated for 20 mins followed by addition of adrenaline as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of rat COMTMore data for this Ligand-Target Pair