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Found 11 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 8/19'
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM576460(US11471446, Compound DBA-1)
Affinity DataEC50:  1.20E+3nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM576461(US11471446, Compound DBA-2)
Affinity DataEC50:  1.50E+4nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM576462(US11471446, Compound DBA-3)
Affinity DataEC50:  1.10E+4nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM576463(US11471446, Compound DBA-4)
Affinity DataEC50:  2.80E+3nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM576464(US11471446, Compound DBA-5)
Affinity DataEC50:  1.70E+3nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM50073190(CHEMBL3408213 | US11471446, Compound DBA-11)
Affinity DataEC50:  20nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM576466(US11471446, Compound DBA-7)
Affinity DataEC50:  25nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM50459994(CHEMBL4226806 | US11471446, Compound DBA-8)
Affinity DataEC50:  500nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM50248629(CHEMBL4076837 | US11471446, Compound DBA-9)
Affinity DataEC50:  50nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataEC50:  20nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 8/19(Homo sapiens (Human))
Lu License

US Patent
LigandPNGBDBM576465(US11471446, Compound DBA-6)
Affinity DataEC50:  180nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent