Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with Target = 'DNA repair endonuclease XPF'
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50504115(CHEMBL4470176)
Affinity DataIC50:  330nMAssay Description:Inhibition of human His6-tagged ERCC1-XPF endonuclease activity expressed in Escherichia coli BL21 (DE3) using [6-FAM-5'-CAGCGCTCGG(20T)CCGAGCGCTG-3'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataIC50:  490nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human His6-tagged ERCC1-XPF endonuclease activity expressed in Escherichia coli BL21 (DE3) using [6-FAM-5'-CAGCGCTCGG(20T)CCGAGCGCTG-3'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells using 6-FAM-5'CAGCGCTCGG(20T)CCGAGCGCTG-3'-dabcyl measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM81244(4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]-2-[(...)
Affinity DataKd:  140nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair endonuclease XPF(Homo sapiens)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50555906(CHEMBL4759590)
Affinity DataKd:  85nMAssay Description:Binding affinity to His-tagged human ERCC1-XPF expressed in Escherichia coli BL21 (DE3) cells by steady-state fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed