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Found 10 Enz. Inhib. hit(s) with Target = 'CAD protein'
TargetCAD protein(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50010599(6-Mercaptomethyl-2-oxo-2,3,4,5-tetrahydro-pyrimidi...)
Affinity DataKi:  140nMpH: 7.4Assay Description:Inhibitory activity against Dihydroorotase (DHO) at pH 7.4 and 8.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50020110((4S,6R)-6-Mercaptomethyl-2-oxo-hexahydro-pyrimidin...)
Affinity DataKi:  140nMAssay Description:Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50291969((2R,4S)-4-Mercapto-4,6-dioxo-4lambda*5*-[1,4]azaph...)
Affinity DataKi:  2.90E+3nMAssay Description:Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50291969((2R,4S)-4-Mercapto-4,6-dioxo-4lambda*5*-[1,4]azaph...)
Affinity DataKi:  3.10E+3nMAssay Description:Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50067883(4-Hydroxy-4,6-dioxo-4lambda*5*-[1,4]azaphosphinane...)
Affinity DataKi:  4.00E+3nMAssay Description:Compound ability to inhibit the catalytic activity of hamster Dihydroorotase (DHOase) expressed in E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50010600(CHEMBL168878 | Ethyl-3-borono-2-(carbamylamino)pro...)
Affinity DataKi:  5.07E+3nMpH: 7.4Assay Description:Inhibitory activity against Dihydroorotase (DHO) at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405110(CHEMBL306140)
Affinity DataIC50:  1.80E+5nMpH: 7.37Assay Description:Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405111(CHEMBL73819)
Affinity DataIC50:  5.20E+5nMpH: 7.37Assay Description:Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405109(CHEMBL1627199)
Affinity DataIC50: >1.00E+6nMpH: 7.37Assay Description:Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCAD protein(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405112(CHEMBL308628)
Affinity DataIC50: >1.00E+6nMpH: 7.37Assay Description:Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed