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Found 10 Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase 10'
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50250606(CHEMBL4077342)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441296(CHEMBL2431665 | CHEMBL2431667)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  2.90E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50087856(CHEMBL3426913)
Affinity DataIC50:  5.70E+3nMpH: 7.0Assay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed