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Found 10 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [671-1210,L858R]'
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27970(1-{4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohex...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27968(4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H-1,...)
Affinity DataIC50:  25nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27965(3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27967(ethyl 4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27969(3-{2-[(2-methoxyphenyl)methyl]-1H-1,3-benzodiazol-...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27964(3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-5-yl)-1...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27963(3-(2-(2-chlorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-...)
Affinity DataIC50:  65nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27966(1-{4-[4-(4-amino-3-{2-[(2-methoxyphenyl)methyl]-1H...)
Affinity DataIC50:  130nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27961(3-(2-benzyl-1H-1,3-benzodiazol-6-yl)-1-[4-(morphol...)
Affinity DataIC50:  270nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [671-1210,L858R](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27962(1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...)
Affinity DataIC50:  361nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed