TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 50nM ΔG°: -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibitory activity of the compound was measured on recombinant human Glutathione S-transferase PMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Time dependent inhibition of GSTP1-1 (unknown origin) assessed as inhibition constant using reduced GSH and CDNB as substrate by spectrophotometric m...More data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Inhibitory activity of the compound was measured on recombinant human Glutathione S-transferase PMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Inhibition constant against glutathione S-transferase pi using GSH (0.1-3mM), 1 mM 1-chloro-2,4-dinitrobenzeneMore data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [158-852](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 550nM ΔG°: -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Affinity DataKi: 660nMAssay Description:Inhibition constant against glutathione S-transferase pi using GSH (0.1-3mM), 1 mM 1-chloro-2,4-dinitrobenzeneMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Inhibitory activity of the compound was measured on recombinant human Glutathione S-transferase PMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+3nMAssay Description:Inhibition constant against glutathione S-transferase pi using GSH (0.1-3mM), 1 mM 1-chloro-2,4-dinitrobenzeneMore data for this Ligand-Target Pair
Affinity DataKi: 1.85E+3nMAssay Description:Time dependent inhibition of GSTP1-1 (unknown origin) assessed as inhibition constant using reduced GSH and CDNB as substrate by spectrophotometric m...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876](Homo sapiens (Human))
Oryzon Genomics
US Patent
Oryzon Genomics
US Patent
Affinity DataKi: 5.50E+3nM ΔG°: -31.2kJ/molepH: 7.4 T: 2°CAssay Description:The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...More data for this Ligand-Target Pair
Affinity DataKi: 6.10E+3nMAssay Description:Inhibitory activity of the compound for human Glutathione S-transferase P was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory activity of the compound was measured on recombinant human Glutathione S-transferase PMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+4nMAssay Description:Inhibitory activity of the compound was measured on recombinant human Glutathione S-transferase PMore data for this Ligand-Target Pair
Affinity DataKi: 1.24E+5nMAssay Description:Inhibitory activity of the compound for human glutathione S-transferase-pi isozyme was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 1.87E+5nMAssay Description:Inhibition constant against glutathione S-transferase pi using GSH (0.1-3mM), 1 mM 1-chloro-2,4-dinitrobenzeneMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+5nMAssay Description:Inhibitory activity of the compound was measured on recombinant human Glutathione S-transferase PMore data for this Ligand-Target Pair
Affinity DataKi: 7.10E+5nMAssay Description:Inhibitory activity of the compound was measured on recombinant human Glutathione S-transferase PMore data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 0.959nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D](Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.11nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.29nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.29nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.56nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair