Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with Target = 'Growth/differentiation factor 8'
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50539387(CHEMBL4648474)
Affinity DataIC50:  130nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  130nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50585028(CHEMBL5078185)
Affinity DataIC50:  190nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  260nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50537170(CHEMBL4516740)
Affinity DataIC50:  260nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50254771(CHEMBL4061416)
Affinity DataIC50:  290nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50585029(CHEMBL5092917)
Affinity DataIC50:  300nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50254771(CHEMBL4061416)
Affinity DataIC50:  320nMAssay Description:Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50254771(CHEMBL4061416)
Affinity DataIC50:  360nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50206029(CHEMBL3892004)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50206029(CHEMBL3892004)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant myostatin expressed in HEK293 cells after 4 hrs by SBE4 based luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50071380(CHEMBL3410232)
Affinity DataIC50:  3.56E+3nMAssay Description:Inhibition of recombinant myostatin (unknown origin) expressed in HEK293 cells after 4 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50525413(CHEMBL4448117)
Affinity DataIC50:  3.56E+3nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50071379(CHEMBL3410227)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant myostatin pre-incubated with compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50539386(CHEMBL4646947)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of myostatin (unknown origin) expressed in HEK293 cells incubated for 4 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Mus musculus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095122(CHEMBL3589518)
Affinity DataIC50:  4.79E+4nMAssay Description:Antagonist activity at myostatin in mouse LbetaT2 cells transfected with -338 promoter region of FSHbeta gene conjugated to luciferase reporter asses...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50071381(CHEMBL3410234)
Affinity DataKd:  117nMAssay Description:Binding affinity to recombinant myostatin (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50071379(CHEMBL3410227)
Affinity DataKd:  36nMAssay Description:Binding affinity to recombinant myostatin (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50071380(CHEMBL3410232)
Affinity DataKd:  30nMAssay Description:Binding affinity to recombinant myostatin (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed