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Found 22 Enz. Inhib. hit(s) with Target = 'Kynureninase'
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288256((R)-2-Amino-3-(2-amino-benzenesulfonyl)-propionic ...)
Affinity DataKi:  70nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataKi:  70nMAssay Description:Compound was tested for the binding affinity against bacterial kynureninaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50109155(2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...)
Affinity DataKi:  100nMAssay Description:Tested for binding affinity of the compound against kynureninase enzyme from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50109155(2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...)
Affinity DataKi:  100nMAssay Description:Inhibition of human kynureninaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50109155(2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...)
Affinity DataKi:  130nMAssay Description:Tested for binding affinity of the compound against kynureninase enzyme from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288255(2-ammonio-4-(2-ammoniophenyl)-4-oxo-(2S)-butanoate)
Affinity DataKi:  4.28E+3nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288257((R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-pho...)
Affinity DataKi:  8.80E+3nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50109155(2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric aci...)
Affinity DataKi:  1.00E+4nMAssay Description:Tested for binding affinity of the compound against kynureninase enzyme from bacterial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataKi:  1.80E+4nMAssay Description:Compound was tested for the binding affinity against kynureninase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288254(2-ammonio-4-oxo-4-phenyl-(2S)-butanoate | CHEMBL31...)
Affinity DataKi:  2.34E+4nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50265459(3-Hydroxyhippuric acid | CHEMBL447627)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of human kynureninaseMore data for this Ligand-Target Pair
TargetKynureninase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288258((R)-2-Benzyloxycarbonylamino-3-(methoxy-phenyl-pho...)
Affinity DataKi:  8.80E+5nMAssay Description:Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescenceMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50069732(2-Amino-3-(2-amino-5-methyl-benzenesulfonyl)-propi...)
Affinity DataIC50:  1.10E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50069731(2-Amino-3-(2-amino-3-fluoro-benzenesulfonyl)-propi...)
Affinity DataIC50:  2.00E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50069729(2-Amino-3-(2-amino-3-methoxy-benzenesulfonyl)-prop...)
Affinity DataIC50:  2.90E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50069730(2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid...)
Affinity DataIC50:  3.60E+4nMAssay Description:Compound was tested for the inhibition of mammalian kynureninase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  6.00E+4nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50040567(CHEMBL158499 | ortho-nitrobenzoyl)alanine)
Affinity DataIC50:  1.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50061907((+/-)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50:  1.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50284766((R)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50:  1.00E+5nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50040570(CHEMBL160527 | NICOTINOYLALANINENAL | nicotinoylal...)
Affinity DataIC50:  8.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50040568(CHEMBL157866 | para-nitrobenzoyl)alanine)
Affinity DataIC50:  9.00E+5nMAssay Description:Ability to inhibit kynureninase was determined in a competitive inhibition assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed