TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataKi: 105nMAssay Description:Competitive inhibition of AEP (unknown origin) using varying levels of Z-AAN-AMC substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMT: 2°CAssay Description:AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of Ixodes ricinus asparaginyl endopeptidasesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
TargetLegumain(Homo sapiens (Human))
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Emory Chemical Biology Discovery Center Emory University School Of Medicine Atlanta
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair