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Found 115 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2 [23-127]'
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431985(US10576064, Example I-185 | US10576064, Example I-...)
Affinity DataIC50:  2nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432016(US10576064, Example I-237 | US10576064, Example I-...)
Affinity DataIC50:  2nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432016(US10576064, Example I-237 | US10576064, Example I-...)
Affinity DataIC50:  2nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431985(US10576064, Example I-185 | US10576064, Example I-...)
Affinity DataIC50:  3nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432043(US10576064, Example I-284)
Affinity DataIC50:  3nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431975(US10576064, Example I-170 | US10576064, Example I-...)
Affinity DataIC50:  4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432019(US10576064, Example I-240)
Affinity DataIC50:  4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432021(US10576064, Example I-244)
Affinity DataIC50:  4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432028(US10576064, Example I-258)
Affinity DataIC50:  4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432042(US10576064, Example I-283)
Affinity DataIC50:  4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432001(US10576064, Example I-216 | US10576064, Example I-...)
Affinity DataIC50:  5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432009(US10576064, Example I-228 | US10576064, Example I-...)
Affinity DataIC50:  5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432011(US10576064, Example I-230)
Affinity DataIC50:  5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432030(US10576064, Example I-261)
Affinity DataIC50:  5nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432001(US10576064, Example I-216 | US10576064, Example I-...)
Affinity DataIC50:  6nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432005(US10576064, Example I-221)
Affinity DataIC50:  7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432040(US10576064, Example I-280)
Affinity DataIC50:  7nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431955(US10576064, Example I-43)
Affinity DataIC50:  8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432044(US10576064, Example I-285)
Affinity DataIC50:  8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432046(US10576064, Example I-287)
Affinity DataIC50:  8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432047(US10576064, Example I-288)
Affinity DataIC50:  8nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432013(US10576064, Example I-233)
Affinity DataIC50:  9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432024(US10576064, Example I-250)
Affinity DataIC50:  9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432025(US10576064, Example I-252)
Affinity DataIC50:  9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432026(US10576064, Example I-254)
Affinity DataIC50:  9nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431984(US10576064, Example I-183)
Affinity DataIC50:  10nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432045(US10576064, Example I-286)
Affinity DataIC50:  10nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431975(US10576064, Example I-170 | US10576064, Example I-...)
Affinity DataIC50:  11nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432009(US10576064, Example I-228 | US10576064, Example I-...)
Affinity DataIC50:  11nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432029(US10576064, Example I-259)
Affinity DataIC50:  11nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432008(US10576064, Example I-226)
Affinity DataIC50:  12nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432012(US10576064, Example I-231)
Affinity DataIC50:  12nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431995(US10576064, Example I-204)
Affinity DataIC50:  15nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431981(US10576064, Example I-177)
Affinity DataIC50:  16nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431987(US10576064, Example I-188)
Affinity DataIC50:  16nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431939(US10576064, Example I-5)
Affinity DataIC50:  17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431960(US10576064, Example I-72)
Affinity DataIC50:  17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432007(US10576064, Example I-224)
Affinity DataIC50:  17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432022(US10576064, Example I-246)
Affinity DataIC50:  17nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432033(US10576064, Example I-266)
Affinity DataIC50:  19nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431991(US10576064, Example I-196)
Affinity DataIC50:  20nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432037(US10576064, Example I-274)
Affinity DataIC50:  20nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431999(US10576064, Example I-212)
Affinity DataIC50:  21nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432031(US10576064, Example I-262)
Affinity DataIC50:  21nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432036(US10576064, Example I-272)
Affinity DataIC50:  25nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432034(US10576064, Example I-268)
Affinity DataIC50:  26nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431992(US10576064, Example I-198)
Affinity DataIC50:  27nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432027(US10576064, Example I-256)
Affinity DataIC50:  27nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM432035(US10576064, Example I-270)
Affinity DataIC50:  27nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM431979(US10576064, Example I-173)
Affinity DataIC50:  29nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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