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Found 108 Enz. Inhib. hit(s) with Target = 'Isoform Tau-F of Microtubule-associated protein tau'
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)
Affinity DataKi:  4.61nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481150(US10906900, Reference 22b)
Affinity DataKi:  8.40nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)
Affinity DataKi:  9.5nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481151(US10906900, Reference 22c)
Affinity DataKi:  12nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481152(US10906900, Reference 22e)
Affinity DataKi:  25.1nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  30.6nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214726(Cyanines, 9)
Affinity DataIC50:  120nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214732(Rhodanines, 20A)
Affinity DataIC50:  170nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214733(Rhodanines, 21A)
Affinity DataIC50:  170nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214734(Rhodanines, 22A)
Affinity DataIC50:  210nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214735(Rhodanines, 23A)
Affinity DataIC50:  230nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214737(Rhodanines, 25A)
Affinity DataIC50:  240nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214736(Rhodanines, 24A)
Affinity DataIC50:  240nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214738(Rhodanines, 26A)
Affinity DataIC50:  260nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM32329((2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-...)
Affinity DataIC50:  280nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM32299(2-[(2Z)-2-[(2E)-2-[[3-(2-hydroxyethyl)-5-methoxy-1...)
Affinity DataIC50:  290nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214739(Rhodanines, 27A)
Affinity DataIC50:  420nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214740(Rhodanines, 28A)
Affinity DataIC50:  470nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50052802(CHEBI:77181 | CRYSTAL VIOLET | Crystal violet (15)...)
Affinity DataIC50:  490nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214729(Malachite green (16))
Affinity DataIC50:  520nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214741(Rhodanines, 29A)
Affinity DataIC50:  540nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214742(Rhodanines, 30A)
Affinity DataIC50:  580nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50241461(3,7-bis(dimethylamino)phenothiazin-5-ium chloride ...)
Affinity DataIC50:  610nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214743(Rhodanines, 31A)
Affinity DataIC50:  650nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214744(Rhodanines, 32A)
Affinity DataIC50:  670nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214745(Rhodanines, 33A)
Affinity DataIC50:  730nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214746(Rhodanines, 34A)
Affinity DataIC50:  750nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214747(Rhodanines, 35A)
Affinity DataIC50:  780nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214748(Rhodanines, 36A)
Affinity DataIC50:  820nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214723(Cyanines, 3)
Affinity DataIC50:  890nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214749(Rhodanines, 37A)
Affinity DataIC50:  940nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM75309((2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-...)
Affinity DataIC50:  960nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214750(Rhodanines, 38A)
Affinity DataIC50:  970nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50387480(CHEMBL467894 | Cyanines, 5)
Affinity DataIC50:  980nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214731(Bindschedler's green (19))
Affinity DataIC50:  1.09E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214751(Rhodanines, 39A)
Affinity DataIC50:  1.09E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214752(Rhodanines, 40A)
Affinity DataIC50:  1.22E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214727(Azure B (11))
Affinity DataIC50:  1.28E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214753(Rhodanines, 41A)
Affinity DataIC50:  1.40E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214754(Rhodanines, 42A | Rhodanines, 50A)
Affinity DataIC50:  1.41E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM576627(US11472776, Example 16)
Affinity DataIC50:  1.70E+3nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214755(Rhodanines, 43A)
Affinity DataIC50:  1.85E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM576467(US11472776, Example 1)
Affinity DataIC50:  1.90E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM576631(US11472776, Example 20)
Affinity DataIC50:  1.90E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214756(Rhodanines, 44A)
Affinity DataIC50:  1.97E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214757(Rhodanines, 45A)
Affinity DataIC50:  2.56E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214724(Cyanines, 6)
Affinity DataIC50:  2.57E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214758(Rhodanines, 46A)
Affinity DataIC50:  3.10E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM576618(US11472776, Example 4)
Affinity DataIC50:  3.19E+3nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM214759(Rhodanines, 47A)
Affinity DataIC50:  3.29E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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