TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 4.61nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 8.40nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 9.5nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 12nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 25.1nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 30.6nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 120nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 170nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 170nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 210nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 230nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 240nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 240nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 260nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 280nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 290nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 420nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 470nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 490nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 520nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 540nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 580nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 610nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 650nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 670nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 730nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 750nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 780nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 820nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 890nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 940nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 960nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 970nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 980nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.09E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.09E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.22E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.28E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.40E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.41E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.70E+3nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.85E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.90E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.90E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 1.97E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 2.56E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 2.57E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 3.10E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 3.19E+3nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataIC50: 3.29E+3nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair