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Found 48 Enz. Inhib. hit(s) with Target = 'Sodium/potassium-transporting ATPase subunit alpha-2/beta-1'
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444975(US10668094, Compound DMcP-(cyclic) | US10668094, C...)
Affinity DataKi:  4.20nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444840(US10668094, Compound DcB-(cyclic) | US10668094, Co...)
Affinity DataKi:  5.40nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444840(US10668094, Compound DcB-(cyclic) | US10668094, Co...)
Affinity DataKi:  8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444840(US10668094, Compound DcB-(cyclic) | US10668094, Co...)
Affinity DataKi:  8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444991(US10668094, Compound DMDMcB-(cyclic))
Affinity DataKi:  8.60nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444983(US10668094, Compound DBz-(cyclic))
Affinity DataKi:  10.1nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444981(US10668094, Compound DEcP-(cyclic))
Affinity DataKi:  14.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444980(US10668094, Compound DcP-(cyclic))
Affinity DataKi:  14.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444984(US10668094, Compound DcH-(cyclic))
Affinity DataKi:  15.2nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231660(DMe (11) | US10668094, Compound DMe)
Affinity DataKi:  15.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231660(DMe (11) | US10668094, Compound DMe)
Affinity DataKi:  15.6nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231659(DEtDA (10))
Affinity DataKi:  16.7nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444975(US10668094, Compound DMcP-(cyclic) | US10668094, C...)
Affinity DataKi:  18.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444989(US10668094, Compound DP)
Affinity DataKi:  18.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231661(DEt (12) | US10668094, Compound DEt)
Affinity DataKi:  18.5nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231657(DSCar (8))
Affinity DataKi:  20nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231653(DGlyN (4))
Affinity DataKi:  20.4nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444977(US10668094, Compound DiB)
Affinity DataKi:  20.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444990(US10668094, Compound DtB)
Affinity DataKi:  21.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231661(DEt (12) | US10668094, Compound DEt)
Affinity DataKi:  23.2nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444994(US10668094, Compound DTMS-(silyl))
Affinity DataKi:  24.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231651(DGly (2))
Affinity DataKi:  25nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231662(DMeCF3 (13) | US10668094, Compound DCF3)
Affinity DataKi:  28.6nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444979(US10668094, Compound DiP)
Affinity DataKi:  28.9nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataKi:  29.5nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444996(US10668094, Compound DcPe-(cyclic))
Affinity DataKi:  33.4nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231664(DbisGly (14))
Affinity DataKi:  34.9nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444978(US10668094, Compound DESA-(sulfonamide))
Affinity DataKi:  38.9nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231662(DMeCF3 (13) | US10668094, Compound DCF3)
Affinity DataKi:  44nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231658(DPrN (9))
Affinity DataKi:  47nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444976(US10668094, Compound DESM-(sulfonyl))
Affinity DataKi:  49.2nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM46355(DIGOXIN | MLS000069819 | SMR000059217 | US10668094...)
Affinity DataKi:  55nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM46355(DIGOXIN | MLS000069819 | SMR000059217 | US10668094...)
Affinity DataKi:  58.7nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231654(DAlaN (5))
Affinity DataKi:  67nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231663(Dbis | Digoxigenin bis-digitoxoside)
Affinity DataKi:  74nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM50286739(4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...)
Affinity DataKi:  90nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231652(DGlMe (3))
Affinity DataKi:  128nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM225707(CS337 | Digoxigenin)
Affinity DataKi:  130nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231650(DOH (1))
Affinity DataKi:  134nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM444982(US10668094, Compound DMSM-(sulfonyl))
Affinity DataKi:  137nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231656(DSerN (7))
Affinity DataKi:  144nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM231655(DSer (6))
Affinity DataKi:  145nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM510514(US11077128, Compound BisAcDcB)
Affinity DataKi:  395nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research And Development

US Patent
LigandPNGBDBM510515(US11077128, Compound TrisAcDcB)
Affinity DataKi:  2.50E+3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Rattus norvegicus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50286739(4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant rat Na+/K+-ATPase alpha2/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Rattus norvegicus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50255111(CHEMBL4092961)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of recombinant rat Na+/K+-ATPase alpha2/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Rattus norvegicus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50255109(CHEMBL4081196)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant rat Na+/K+-ATPase alpha2/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Rattus norvegicus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50255122(CHEMBL4059538)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant rat Na+/K+-ATPase alpha2/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed