Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-3010,P2914L]'
TargetGenome polyprotein [2420-3010,P2914L](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243456(US9427440, 1)
Affinity DataKd:  6.40E+3nM Kon:  0.0220M-1s-1 Koff:  3.40E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010,P2914L](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243456(US9427440, 1)
Affinity DataKd:  3.80E+3nM Kon:  0.0220M-1s-1 Koff:  5.90E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In DepthDetails US Patent