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Found 159 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-3010]'
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243470(US9427440, 18)
Affinity DataIC50:  26nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243471(US9427440, 19)
Affinity DataIC50:  31nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243456(US9427440, 1)
Affinity DataIC50:  38nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243472(US9427440, 20)
Affinity DataIC50:  38nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243468(US9427440, 16)
Affinity DataIC50:  40nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243461(US9427440, 13)
Affinity DataIC50:  190nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243457(US9427440, 11)
Affinity DataIC50:  220nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243456(US9427440, 1)
Affinity DataIC50:  240nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243460(US9427440, 10)
Affinity DataIC50:  280nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243458(US9427440, 5)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243455(US9427440, 2)
Affinity DataIC50:  410nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243462(US9427440, 3)
Affinity DataIC50:  530nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243459(US9427440, 12)
Affinity DataIC50:  930nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM249199(US9457039, 22)
Affinity DataIC50:  930nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM249201(US9457039, 24)
Affinity DataIC50:  1.10E+3nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM246468(US9447132, Formula IV)
Affinity DataIC50:  1.40E+3nMpH: 7.5Assay Description:NS5B RNA polymerase reactions for IC50 determination were performed in 96-well microtiter plates in 20 μL reactions containing assay buffer (50 ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM64587(US9447132, GS-7977 | sofosbuvir)
Affinity DataIC50:  2.10E+3nMpH: 7.5Assay Description:NS5B RNA polymerase reactions for IC50 determination were performed in 96-well microtiter plates in 20 μL reactions containing assay buffer (50 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243463(US9427440, 4)
Affinity DataIC50:  2.42E+3nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM249200(US9457039, 23)
Affinity DataIC50:  6.70E+3nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM241872(US9416154, 15)
Affinity DataIC50: >2.00E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM241899(US9416154, 37)
Affinity DataIC50:  4.00E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM249202(US9457039, 25)
Affinity DataIC50:  5.10E+4nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM241898(US9416154, 36)
Affinity DataIC50:  6.50E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240838(US9394331, 135 | US9394331, 32)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240839(US9394331, 138 | US9394331, 50)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240840(US9394331, 36)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240841(US9394331, 139 | US9394331, 51)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240842(US9394331, 44)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240843(US9394331, 137 | US9394331, 49)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240844(US9394331, 136 | US9394331, 48)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240845(US9394331, 140 | US9394331, 52)
Affinity DataEC50: >5.45E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240846(US9394331, 62)
Affinity DataEC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240847(US9394331, 72)
Affinity DataEC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240848(US9394331, 76)
Affinity DataEC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240849(US9394331, 77)
Affinity DataEC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240850(US9394331, 66)
Affinity DataEC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240851(US9394331, 114)
Affinity DataEC50:  2.06E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240852(US9394331, 115)
Affinity DataEC50:  2.85E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240853(US9394331, 116)
Affinity DataEC50:  2.83E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240854(US9394331, 117)
Affinity DataEC50:  1.67E+4nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240855(US9394331, 113)
Affinity DataEC50:  1.55E+3nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240856(US9394331, 118 | US9394331, 119)
Affinity DataEC50:  1.49E+3nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240856(US9394331, 118 | US9394331, 119)
Affinity DataEC50:  4.52E+3nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240858(US9394331, 120 | US9394331, 121)
Affinity DataEC50:  390nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240858(US9394331, 120 | US9394331, 121)
Affinity DataEC50:  9.31E+3nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240860(US9394331, 122)
Affinity DataEC50:  857nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240861(US9394331, 123)
Affinity DataEC50:  310nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240862(US9394331, 124)
Affinity DataEC50:  566nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240863(US9394331, 125)
Affinity DataEC50:  4.42E+3nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM240864(US9394331, 126 | US9394331, 127)
Affinity DataEC50:  274nMpH: 7.5 T: 2°CAssay Description:The HCV NS5B reaction was performed in a 20 μL mixture containing varying concentrations of the test compound, 1 μM of all four natural ribonuc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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