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Found 35 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase S'
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM23411(5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50131836(CHEMBL3633138)
Affinity DataIC50:  600nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50499947(CHEMBL3739950)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50499946(CHEMBL3740878)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50131837(CHEMBL3633139)
Affinity DataIC50:  900nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26661(7,3,4,5-tetrahydroxyflavone | 7-hydroxy-2-(3,4,5-t...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50353440(CHEMBL1829864 | US10196373, Compound 45F)
Affinity DataIC50:  4.30E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50499945(CHEMBL3740356)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50499944(CHEMBL3739990)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50131835(CHEMBL3632914)
Affinity DataIC50:  7.90E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of PTPsigma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPsigma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50499948(CHEMBL3741920)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50131834(CHEMBL3632913)
Affinity DataIC50:  1.18E+4nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50131833(CHEMBL3632912)
Affinity DataIC50:  1.56E+4nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26656(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50530496(CHEMBL4577930)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50530496(CHEMBL4577930)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558461(CHEMBL4760367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558485(CHEMBL4800195)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPsigma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558484(CHEMBL4748824)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558481(CHEMBL4783639)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558486(CHEMBL4797766)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558487(CHEMBL4786243)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPsigma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558483(CHEMBL4778085)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50558482(CHEMBL4742123)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed