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Found 1 Enz. Inhib. hit(s) with Target = 'Rho guanine nucleotide exchange factor 1'
TargetRho guanine nucleotide exchange factor 1(Homo sapiens)
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Curated by ChEMBL
LigandPNGBDBM50056922(1,4-Dihydroxy-10-methoxy-5,8-dimethyl-3,7-dioxo-1,...)
Affinity DataIC50:  1.87E+5nMAssay Description:Inhibition of p115 DHPH22 domain (395 to 766 residues) (unknown origin) interaction with GDP-loaded His-tagged RhoA F25N mutant (1 to 180 residues) a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed