Affinity DataKi: 5.50E+3nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nM ΔG°: -30.6kJ/mole IC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+4nMAssay Description:Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable...More data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable...More data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nMAssay Description:Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable...More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as KiMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable...More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable...More data for this Ligand-Target Pair
Affinity DataKi: 6.10E+4nM ΔG°: -25.0kJ/mole IC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+4nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nM ΔG°: -23.7kJ/mole IC50: 1.40E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+5nM ΔG°: -23.6kJ/mole IC50: 1.10E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+5nM ΔG°: -22.9kJ/mole IC50: 3.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+5nM ΔG°: -22.9kJ/mole IC50: 4.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+5nMAssay Description:Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as KiMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as KiMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as KiMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as KiMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as KiMore data for this Ligand-Target Pair
Affinity DataKi: 4.10E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as KiMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Competitive inhibitory activity against Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 5.20E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 5.30E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+5nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+6nMAssay Description:Competitive inhibitory activity against M-2 Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+6nMAssay Description:Competitive inhibitory activity against Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as S-adenosyl methionine production using L-methionine as substrate pretreated for 60 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human MAT2A expressed in baculovirus infected Sf9 cells expression system assessed as S-adenosyl methionine production using L-methioni...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of MT2A in MTAP-null human HCT-116 cells after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of MT2A in MTAP-null human HCT-116 cells after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of MT2A in MTAP-null human HCT-116 cells after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of MT2A in MTAP-null human HCT-116 cells after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Recombinant human Mat2a (12.5 nM) and serial diluted compounds in DMSO (range of concentrations from 10 μM to 508 μM) or controls (DMSO) ar...More data for this Ligand-Target Pair