Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Short transient receptor potential channel 7'
TargetShort transient receptor potential channel 7(Homo sapiens)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50:  226nMAssay Description:Inhibition of human TRPC7 expressed in HEK293 cells assessed as reduction in OAG-induced calcium influx after 10 mins by fluo-4/AM dye based FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM85747(CAS_442-52-4 | CLEMIZOLE HYDROCHLORIDE | NSC_2782 ...)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of YFP-tagged mouse TRPC7 expressed in thapsigargin treated HEK293 cells assessed as reduction in amix-induced calcium level by fluo-4 dye...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50239162(CHEMBL4060400)
Affinity DataEC50:  314nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  497nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50239161(CHEMBL4085233)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50239160(CHEMBL4060387)
Affinity DataEC50:  213nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 7(Homo sapiens)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  1.13E+3nMAssay Description:Agonist activity at human TRPC7 receptor expressed in HEK293 cells assessed as induction of channel current in presence of 0.1 mM Ca2+ by whole cell ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed