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Found 1049 Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase'
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  0.640nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human Telomerase activity in cell free system by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50:  13nMAssay Description:Inhibition of telomerase activity in human M14 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50:  13nMAssay Description:Inhibition of telomerase activity in human HT-29 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50:  13nMAssay Description:Inhibition of telomerase activity in human H125 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50:  13nMAssay Description:Inhibition of telomerase activity in human MCF7 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50310892(CHEMBL1078511 | N,N'-(9-(2-(1-methylpyrrolidin-2-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50310892(CHEMBL1078511 | N,N'-(9-(2-(1-methylpyrrolidin-2-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134027(CHEMBL140180 | N,N'-(9-(2-(dimethylamino)ethylamin...)
Affinity DataIC50:  18nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134010(CHEMBL139511 | N,N'-(9-(2-aminophenylamino)acridin...)
Affinity DataIC50:  20nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50440391(CHEMBL2425367)
Affinity DataIC50:  28nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50196500(CHEMBL224754 | trimethyl(2-{6,8,17,19-tetraoxo-18-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of telomerase in JR8 cell extract by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134022(CHEMBL336444 | N,N'-(9-(4-acetylphenylamino)acridi...)
Affinity DataIC50:  40nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50487893(CHEMBL2260109)
Affinity DataIC50:  41nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50487893(CHEMBL2260109)
Affinity DataIC50:  41nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134030(9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  45nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489002(CHEMBL2298058)
Affinity DataIC50:  49nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489002(CHEMBL2298058)
Affinity DataIC50:  49nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134032(CHEMBL138811 | N,N'-(9-(cyclopropylamino)acridine-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50058033(CHEMBL3330787)
Affinity DataIC50:  50nMAssay Description:Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134002(CHEMBL141540 | N,N'-(9-(2-(piperidin-1-yl)ethylami...)
Affinity DataIC50:  50nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489008(CHEMBL2298055)
Affinity DataIC50:  51nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489008(CHEMBL2298055)
Affinity DataIC50:  51nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  52nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50488996(CHEMBL2298050)
Affinity DataIC50:  56nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50488996(CHEMBL2298050)
Affinity DataIC50:  56nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  58nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134019(CHEMBL336417 | N,N'-(9-(3-aminophenylamino)acridin...)
Affinity DataIC50:  60nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50196492(2,9-bis-[2-(2-hydroxy-ethylamino)-ethyl]-anthra[2,...)
Affinity DataIC50:  60nMAssay Description:Inhibition of telomerase in JR8 cell extract by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134018(CHEMBL335819 | N,N'-(9-(4-aminophenylamino)acridin...)
Affinity DataIC50:  60nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50107609(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Affinity DataIC50:  60nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134009(CHEMBL335132 | N,N'-(9-(3-(dimethylamino)propylami...)
Affinity DataIC50:  60nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50:  63nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  63nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134030(9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134025(CHEMBL343795 | N,N'-(9-(4-fluorophenylamino)acridi...)
Affinity DataIC50:  70nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50058035(CHEMBL3330789)
Affinity DataIC50:  70nMAssay Description:Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134018(CHEMBL335819 | N,N'-(9-(4-aminophenylamino)acridin...)
Affinity DataIC50:  74nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50058037(CHEMBL3330791)
Affinity DataIC50:  80nMAssay Description:Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134008(CHEMBL138187 | N,N'-(9-(3-(dimethylamino)propylami...)
Affinity DataIC50:  80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134023(CHEMBL337762 | N,N'-(9-(4-aminophenylamino)acridin...)
Affinity DataIC50:  80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50150618(CHEMBL182871 | Hexanedioic acid {4-[3,6-bis-(3-pyr...)
Affinity DataIC50:  80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134000(CHEMBL139287 | N,N'-(9-(cyclohexylamino)acridine-3...)
Affinity DataIC50:  90nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134030(9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human telomerase in A549 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50:  93nMAssay Description:Inhibition of telomerase in human HeLa cells after 2 hrs by [alpha-32P]dGTP incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human telomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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