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Found 16 Enz. Inhib. hit(s) with Target = 'Thioredoxin reductase 2, mitochondrial'
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)
Affinity DataIC50:  7.45E+3nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)
Affinity DataIC50:  7.45E+3nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50005886(1,8-Dihydroxy-3-methoxy-6-methylanthraquinone | 1,...)
Affinity DataIC50:  1.32E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50455992(CHEBI:3687 | Chrysophanol)
Affinity DataIC50:  1.81E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM80739(MLS002473001 | SMR001397106 | cid_91440 | sennosid...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50333879(CHEMBL1644068 | Skyrin glucoside)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50333878(CHEMBL1172006 | Frangulin A)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50274681(CARBOPLATIN | cbdca | cbdca(2-) | cyclobutane-1,1-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat TrxR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50085551(1,8-Dihydroxy-3-hydroxymethyl-anthraquinone | 1,8-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM11316(1,8-dihydroxy-9,10-dihydroanthracene-9,10-dione | ...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-Dihydroxyanthrachinon | 1,4-dihydroxy-9,10-ant...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50060860(9(10H)-anthracenone | 9,10-dihydro-9-oxoanthracene...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50269016(CHEMBL497001 | aloin)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed