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Found 456 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 3'
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155803(US9012651, 247)
Affinity DataIC50:  80nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155784(US9012651, 223)
Affinity DataIC50:  80nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155667(US9012651, 97)
Affinity DataIC50:  110nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155664(US9012651, 94)
Affinity DataIC50:  120nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155826(US9012651, 273)
Affinity DataIC50:  120nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155846(US9012651, 294)
Affinity DataIC50:  120nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155842(US9012651, 289)
Affinity DataIC50:  130nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155643(US9012651, 73)
Affinity DataIC50:  140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155789(US9012651, 228)
Affinity DataIC50:  140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155669(US9012651, 99)
Affinity DataIC50:  140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155785(US9012651, 224)
Affinity DataIC50:  140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM47251(US9012651, 71)
Affinity DataIC50:  160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155802(US9012651, 246)
Affinity DataIC50:  160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155801(US9012651, 245)
Affinity DataIC50:  160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155800(US9012651, 244)
Affinity DataIC50:  160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50187697(CHEMBL3828278)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at human TRPV3 expressed in recombinant HEK293 cells assessed as inhibition of 2-APB induced calcium flux by FLIPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155819(US9012651, 264)
Affinity DataIC50:  170nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155841(US9012651, 288)
Affinity DataIC50:  170nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM47273(US9012651, 290)
Affinity DataIC50:  170nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155822(US9012651, 267)
Affinity DataIC50:  180nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155641(US9012651, 70)
Affinity DataIC50:  180nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155820(US9012651, 265)
Affinity DataIC50:  190nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155633(US9012651, 61)
Affinity DataIC50:  190nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190576(US9181219, 6)
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190579(US9181219, 20)
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190583(US9181219, 10)
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190585(US9181219, 2-{[3-fluoro-5-(trifluoromethyl)pyridin...)
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190588(US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190593(US9181219, 2-[(4,5-dimethylpyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190585(US9181219, 2-{[3-fluoro-5-(trifluoromethyl)pyridin...)
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190588(US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM190593(US9181219, 2-[(4,5-dimethylpyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155591(US9012651, 17)
Affinity DataIC50:  200nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM47272(US9012651, 272)
Affinity DataIC50:  220nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155638(US9012651, 66)
Affinity DataIC50:  220nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155811(US9012651, 255)
Affinity DataIC50:  230nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155818(US9012651, 263)
Affinity DataIC50:  230nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155593(US9012651, 19)
Affinity DataIC50:  230nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155833(US9012651, 280)
Affinity DataIC50:  250nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155836(US9012651, 283)
Affinity DataIC50:  260nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155673(US9012651, 103)
Affinity DataIC50:  260nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155827(US9012651, 274)
Affinity DataIC50:  260nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155663(US9012651, 93)
Affinity DataIC50:  270nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155844(US9012651, 292)
Affinity DataIC50:  280nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155619(US9012651, 47)
Affinity DataIC50:  290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155814(US9012651, 258)
Affinity DataIC50:  290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155796(US9012651, 238)
Affinity DataIC50:  290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155650(US9012651, 80)
Affinity DataIC50:  290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155816(US9012651, 260)
Affinity DataIC50:  300nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM155656(US9012651, 86)
Affinity DataIC50:  300nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
In DepthDetails US Patent
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