Found 456 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 3'
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 80nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 80nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 110nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 120nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 120nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 120nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 130nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 140nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 160nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human TRPV3 expressed in recombinant HEK293 cells assessed as inhibition of 2-APB induced calcium flux by FLIPR analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 170nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 170nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 170nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 180nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 180nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 190nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 190nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:Phase 1: TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separatio...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: <200nMAssay Description:To determine whether compounds were selective for TRPV3 inhibition over inhibition of other ion channel types, the human ERG (hERG), NaV1.2, and TRPV...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 200nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 220nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 220nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 230nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 230nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 230nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 250nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 260nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 260nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 260nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 270nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 280nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 290nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 300nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Abbvie
US Patent
Abbvie
US Patent
Affinity DataIC50: 300nMAssay Description:Experiments were conducted using the FLIPRTETRAŽ. On the day prior to the experiment, recombinant HEK293 cells that stably express human and mouse TR...More data for this Ligand-Target Pair