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Found 8 Enz. Inhib. hit(s) with Target = 'Tyrosine 3-monooxygenase'
TargetTyrosine 3-monooxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of rat tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50007422((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Affinity DataIC50:  300nMAssay Description:Inhibition of tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50007425((S) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Bos taurus)
Orion

Curated by ChEMBL
LigandPNGBDBM50017845(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-(3,4,5-trimetho...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibitory activity against the tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Bos taurus)
Orion

Curated by ChEMBL
LigandPNGBDBM50017850(1-(3,4-Dihydroxy-phenyl)-2-methyl-propan-1-one | C...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory activity against the tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM84636(CHEMBL27559 | NPA-11-OH-R,(+))
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Bos taurus)
Orion

Curated by ChEMBL
LigandPNGBDBM50017857(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against the tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine 3-monooxygenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50023739((S)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed