Affinity DataKi: 2.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Tyrosyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherich...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Tyrosyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherich...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.48E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+4nMAssay Description:Compound was tested for the inhibition of aminoacyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.9 T: 2°CAssay Description:The concentration of inhibitor which results in 50% inhibition (IC50) of enzyme activity was determined by preincubating recombinant S. aureus TyrRS ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.9 T: 2°CAssay Description:The concentration of inhibitor which results in 50% inhibition (IC50) of enzyme activity was determined by preincubating recombinant S. aureus TyrRS ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.9 T: 2°CAssay Description:The concentration of inhibitor which results in 50% inhibition (IC50) of enzyme activity was determined by preincubating recombinant S. aureus TyrRS ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.9 T: 2°CAssay Description:The concentration of inhibitor which results in 50% inhibition (IC50) of enzyme activity was determined by preincubating recombinant S. aureus TyrRS ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 245nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+3nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.55E+3nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.11E+3nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.92E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.19E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.67E+4nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair