BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50036459 CCCCc1nn(-c2c(Cl)cccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 |(.21,-2.67,;1.31,-3.74,;2.78,-3.34,;3.9,-4.42,;5.37,-4,;5.91,-2.57,;7.45,-2.62,;8.41,-1.41,;7.84,.02,;6.3,.23,;8.78,1.21,;10.31,1,;10.88,-.44,;9.92,-1.64,;10.48,-3.09,;7.87,-4.11,;9.31,-4.65,;6.59,-4.95,;6.52,-6.49,;7.82,-7.33,;7.73,-8.87,;9.04,-9.69,;10.41,-8.98,;10.46,-7.43,;9.17,-6.61,;11.7,-9.8,;11.63,-11.35,;12.93,-12.16,;14.29,-11.46,;14.36,-9.9,;13.05,-9.08,;13.11,-7.54,;14.65,-7.54,;11.57,-7.54,;13.1,-6,;14.43,-5.23,;14.42,-3.69,;15.77,-5.98,;15.78,-7.52,;17.11,-8.28,;18.44,-7.5,;18.42,-5.96,;17.09,-5.2,)| InChI=1S/C32H28Cl2N4O4S/c1-2-3-16-29-35-38(30-26(33)13-9-14-27(30)34)32(40)37(29)21-22-17-19-23(20-18-22)25-12-7-8-15-28(25)43(41,42)36-31(39)24-10-5-4-6-11-24/h4-15,17-20H,2-3,16,21H2,1H3,(H,36,39) ZEJZITXXPIVLML-UHFFFAOYSA-N 50039919 4'-[3-Butyl-1-(2,6-dichloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL18606 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.6 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039919 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039919&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 11764669 103947114 CHEMBL18606 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036460 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1(C)CC1(Cl)Cl InChI=1S/C31H29Cl2F3N4O4S/c1-3-4-13-26-37-40(24-11-7-6-10-23(24)31(34,35)36)28(42)39(26)18-20-14-16-21(17-15-20)22-9-5-8-12-25(22)45(43,44)38-27(41)29(2)19-30(29,32)33/h5-12,14-17H,3-4,13,18-19H2,1-2H3,(H,38,41) RKRHFJADZOJHBH-UHFFFAOYSA-N 50039870 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-dichloro-1-methyl-cyclopropanecarbonyl)-amide::CHEMBL328434 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.370000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039870 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039870&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349597 103947065 CHEMBL328434 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036461 CCCCc1nc(c(n1Cc2ccc(cc2)c3ccccc3c4[nH]nnn4)C(=O)O)Cl InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28) ZEUXAIYYDDCIRX-UHFFFAOYSA-N 50006909 2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::E 3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::EXP3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL907::Carboxylic Acid Metabolite (E-3174) Type-1 angiotensin II receptor Oryctolagus cuniculus 2.8 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006909&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search A1ATL 9BR7 108185 103920212 CHEMBL907 C15554 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036462 CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nn(-c3ccccc3C(F)(F)F)c2=O)cc1 InChI=1S/C31H33F3N4O5S/c1-3-5-15-28-35-38(26-13-9-8-12-25(26)31(32,33)34)30(40)37(28)21-22-16-18-23(19-17-22)24-11-7-10-14-27(24)44(41,42)36-29(39)43-20-6-4-2/h7-14,16-19H,3-6,15,20-21H2,1-2H3,(H,36,39) BCSNTIJHQVSLMI-UHFFFAOYSA-N 50039927 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-butoxycarbonyl)benzenesulfonamide::CHEMBL316482 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.590000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039927 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039927&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9960852 103947122 CHEMBL316482 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036463 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCC InChI=1S/C29H29F3N4O5S/c1-3-5-14-26-33-36(24-12-8-7-11-23(24)29(30,31)32)28(38)35(26)19-20-15-17-21(18-16-20)22-10-6-9-13-25(22)42(39,40)34-27(37)41-4-2/h6-13,15-18H,3-5,14,19H2,1-2H3,(H,34,37) FSOKFDUOJSQIKR-UHFFFAOYSA-N 50039856 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-ethoxycarbonyl)benzenesulfonamide::CHEMBL431619 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.2 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039856 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039856&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10393837 103947051 CHEMBL431619 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036464 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(OC)c(OC)c(OC)c1 InChI=1S/C36H35F3N4O7S/c1-5-6-15-32-40-43(28-13-9-8-12-27(28)36(37,38)39)35(45)42(32)22-23-16-18-24(19-17-23)26-11-7-10-14-31(26)51(46,47)41-34(44)25-20-29(48-2)33(50-4)30(21-25)49-3/h7-14,16-21H,5-6,15,22H2,1-4H3,(H,41,44) KOOAAMQSLAQART-UHFFFAOYSA-N 50039893 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 3,4,5-trimethoxy-benzoylamide::CHEMBL97500 Type-1 angiotensin II receptor Oryctolagus cuniculus 21 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039893 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039893&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10259334 103947088 CHEMBL97500 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036465 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1occc1C InChI=1S/C32H29F3N4O5S/c1-3-4-13-28-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(28)20-22-14-16-23(17-15-22)24-9-5-8-12-27(24)45(42,43)37-30(40)29-21(2)18-19-44-29/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) FAZPIUJZFLKBPJ-UHFFFAOYSA-N 50039921 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methyl-furan-2-carbonyl)-amide::CHEMBL328941 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.210000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039921 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039921&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9895635 103947116 CHEMBL328941 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036466 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(C)=O InChI=1S/C27H27ClN4O4S/c1-3-4-13-26-29-32(24-11-7-6-10-23(24)28)27(34)31(26)18-20-14-16-21(17-15-20)22-9-5-8-12-25(22)37(35,36)30-19(2)33/h5-12,14-17H,3-4,13,18H2,1-2H3,(H,30,33) PXKSZDRAQKHPND-UHFFFAOYSA-N 50039933 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid acetyl-amide::CHEMBL318042 Type-1 angiotensin II receptor Oryctolagus cuniculus 13 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039933 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039933&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10437270 103947128 CHEMBL318042 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036467 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCC(C)C InChI=1S/C31H33F3N4O5S/c1-4-5-14-28-35-38(26-12-8-7-11-25(26)31(32,33)34)30(40)37(28)19-22-15-17-23(18-16-22)24-10-6-9-13-27(24)44(41,42)36-29(39)43-20-21(2)3/h6-13,15-18,21H,4-5,14,19-20H2,1-3H3,(H,36,39) LETRMRLPBCPJMA-UHFFFAOYSA-N 50039864 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-isobutoxycarbonyl)benzenesulfonamide::CHEMBL97068 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.420000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039864 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039864&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077743 103947059 CHEMBL97068 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036468 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCC1 InChI=1S/C32H33F3N4O4S/c1-2-3-16-29-36-39(27-14-8-7-13-26(27)32(33,34)35)31(41)38(29)21-22-17-19-23(20-18-22)25-12-6-9-15-28(25)44(42,43)37-30(40)24-10-4-5-11-24/h6-9,12-15,17-20,24H,2-5,10-11,16,21H2,1H3,(H,37,40) BPMHTBBVCZRJAP-UHFFFAOYSA-N 50039924 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclopentanecarbonyl-amide::CHEMBL316273 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.320000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039924 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039924&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054708 103947119 CHEMBL316273 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036469 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCCC1 InChI=1S/C33H35F3N4O4S/c1-2-3-17-30-37-40(28-15-9-8-14-27(28)33(34,35)36)32(42)39(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)45(43,44)38-31(41)25-11-5-4-6-12-25/h7-10,13-16,18-21,25H,2-6,11-12,17,22H2,1H3,(H,38,41) KLYVARHCIOHMIV-UHFFFAOYSA-N 50039880 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclohexanecarbonyl-amide::CHEMBL94905 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.150000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039880 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039880&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326797 103947075 CHEMBL94905 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036470 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCCCC1 InChI=1S/C34H37F3N4O4S/c1-2-3-18-31-38-41(29-16-10-9-15-28(29)34(35,36)37)33(43)40(31)23-24-19-21-25(22-20-24)27-14-8-11-17-30(27)46(44,45)39-32(42)26-12-6-4-5-7-13-26/h8-11,14-17,19-22,26H,2-7,12-13,18,23H2,1H3,(H,39,42) FTJIFYIITVETKU-UHFFFAOYSA-N 50039904 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cycloheptanecarbonyl-amide::CHEMBL329099 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.300000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039904 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039904&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326972 103947099 CHEMBL329099 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036471 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1(C)CC1 InChI=1S/C31H31F3N4O4S/c1-3-4-13-27-35-38(25-11-7-6-10-24(25)31(32,33)34)29(40)37(27)20-21-14-16-22(17-15-21)23-9-5-8-12-26(23)43(41,42)36-28(39)30(2)18-19-30/h5-12,14-17H,3-4,13,18-20H2,1-2H3,(H,36,39) QNLLWVNFFXLKJP-UHFFFAOYSA-N 50039875 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (1-methyl-cyclopropanecarbonyl)-amide::CHEMBL327563 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.800000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039875 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039875&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10483888 103947070 CHEMBL327563 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036472 CCCCCCCC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nn(-c3ccccc3C(F)(F)F)c2=O)cc1 InChI=1S/C34H39F3N4O4S/c1-3-5-7-8-9-19-32(42)39-46(44,45)30-17-13-10-14-27(30)26-22-20-25(21-23-26)24-40-31(18-6-4-2)38-41(33(40)43)29-16-12-11-15-28(29)34(35,36)37/h10-17,20-23H,3-9,18-19,24H2,1-2H3,(H,39,42) FEZRQMGQHANOOE-UHFFFAOYSA-N 50039915 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid octanoyl-amide::CHEMBL274712 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.9 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039915 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039915&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055096 103947110 CHEMBL274712 C16236 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036473 FC(F)(F)CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C33H26F6N4O4S/c34-32(35,36)20-8-15-29-40-43(27-13-6-5-12-26(27)33(37,38)39)31(45)42(29)21-22-16-18-23(19-17-22)25-11-4-7-14-28(25)48(46,47)41-30(44)24-9-2-1-3-10-24/h1-7,9-14,16-19H,8,15,20-21H2,(H,41,44) VSSNYYVTPWFYPM-UHFFFAOYSA-N 50039857 4'-[5-Oxo-3-(4,4,4-trifluoro-butyl)-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL414816 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.5 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039857 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039857&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439612 103947052 CHEMBL414816 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036474 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)Cc1ccccc1 InChI=1S/C34H31F3N4O4S/c1-2-3-17-31-38-41(29-15-9-8-14-28(29)34(35,36)37)33(43)40(31)23-25-18-20-26(21-19-25)27-13-7-10-16-30(27)46(44,45)39-32(42)22-24-11-5-4-6-12-24/h4-16,18-21H,2-3,17,22-23H2,1H3,(H,39,42) HVIDQSDPDWZVHO-UHFFFAOYSA-N 50039872 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid phenylacetyl-amide::CHEMBL274710 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.6 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039872&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 11764826 103947067 CHEMBL274710 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036475 CC1CC1Cc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C34H29F3N4O4S/c1-22-19-26(22)20-31-38-41(29-13-7-6-12-28(29)34(35,36)37)33(43)40(31)21-23-15-17-24(18-16-23)27-11-5-8-14-30(27)46(44,45)39-32(42)25-9-3-2-4-10-25/h2-18,22,26H,19-21H2,1H3,(H,39,42) CCJJBAOBCOBULM-UHFFFAOYSA-N 50039878 4'-[3-(2-Methyl-cyclopropylmethyl)-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL94176 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.8 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039878 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039878&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10100723 103947073 CHEMBL94176 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036476 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1F InChI=1S/C33H28F4N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42) VQNOTIYWHVRPAM-UHFFFAOYSA-N 50039862 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-fluoro-benzoylamide::CHEMBL330533 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.130000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039862 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039862&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372093 103947057 CHEMBL330533 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036477 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(F)cc1 InChI=1S/C33H28F4N4O4S/c1-2-3-12-30-38-41(28-10-6-5-9-27(28)33(35,36)37)32(43)40(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)46(44,45)39-31(42)24-17-19-25(34)20-18-24/h4-11,13-20H,2-3,12,21H2,1H3,(H,39,42) HZIBLUNQSCPVRC-UHFFFAOYSA-N 50039860 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-fluoro-benzoylamide::CHEMBL329858 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.680000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039860 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039860&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10009478 103947055 CHEMBL329858 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036478 CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1 InChI=1S/C29H27F3N4O4S/c1-2-7-26-33-36(24-10-5-4-9-23(24)29(30,31)32)28(38)35(26)18-19-12-14-20(15-13-19)22-8-3-6-11-25(22)41(39,40)34-27(37)21-16-17-21/h3-6,8-15,21H,2,7,16-18H2,1H3,(H,34,37) OILHOKMGGIVWPB-UHFFFAOYSA-N 50039898 4'-[5-Oxo-3-propyl-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclopropanecarbonyl-amide::CHEMBL319955 Type-1 angiotensin II receptor Oryctolagus cuniculus 18 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039898 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039898&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10099830 103947093 CHEMBL319955 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036479 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccs1 InChI=1S/C31H27F3N4O4S2/c1-2-3-14-28-35-38(25-11-6-5-10-24(25)31(32,33)34)30(40)37(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)44(41,42)36-29(39)26-12-8-19-43-26/h4-13,15-19H,2-3,14,20H2,1H3,(H,36,39) ONISZXSDXWTXDP-UHFFFAOYSA-N 50039916 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (thiophene-2-carbonyl)-amide::CHEMBL314812 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.940000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039916 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039916&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9830839 103947111 CHEMBL314812 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036480 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1nc2ccccc2o1 InChI=1S/C33H28F3N5O4S/c1-2-3-16-30-38-41(27-13-7-5-11-25(27)33(34,35)36)32(42)40(30)21-22-17-19-23(20-18-22)24-10-4-9-15-29(24)46(43,44)39-31-37-26-12-6-8-14-28(26)45-31/h4-15,17-20H,2-3,16,21H2,1H3,(H,37,39) BXRKFZIBTDBIGD-UHFFFAOYSA-N 50039869 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzooxazol-2-ylamide::CHEMBL327569 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.2 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039869 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039869&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349256 103947064 CHEMBL327569 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036481 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1(C)SCCS1 InChI=1S/C31H31F3N4O4S3/c1-3-4-13-27-35-38(25-11-7-6-10-24(25)31(32,33)34)29(40)37(27)20-21-14-16-22(17-15-21)23-9-5-8-12-26(23)45(41,42)36-28(39)30(2)43-18-19-44-30/h5-12,14-17H,3-4,13,18-20H2,1-2H3,(H,36,39) LIENBRWYZMHTGD-UHFFFAOYSA-N 50039946 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-methyl-[1,3]dithiolane-2-carbonyl)-amide::CHEMBL94145 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.220000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039946 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039946&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417102 103947141 CHEMBL94145 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036482 CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) JGABCUJSSAEYFF-UHFFFAOYSA-N 50009714 CHEMBL191::{2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-3H-imidazol-4-yl}-methanol(DuP 753) Type-1 angiotensin II receptor Oryctolagus cuniculus 40 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009714 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009714&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 44330456 103922696 CHEMBL191 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036483 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ocnc1C InChI=1S/C31H28F3N5O5S/c1-3-4-13-27-36-39(25-11-7-6-10-24(25)31(32,33)34)30(41)38(27)18-21-14-16-22(17-15-21)23-9-5-8-12-26(23)45(42,43)37-29(40)28-20(2)35-19-44-28/h5-12,14-17,19H,3-4,13,18H2,1-2H3,(H,37,40) RMFBHOGJDSQPMB-UHFFFAOYSA-N 50039939 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (4-methyl-oxazole-5-carbonyl)-amide; compound with dichloro-methane::CHEMBL262296 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.1 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039939 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039939&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10461785 103947134 CHEMBL262296 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036484 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccnc1Cl InChI=1S/C32H27ClF3N5O4S/c1-2-3-14-28-38-41(26-12-6-5-11-25(26)32(34,35)36)31(43)40(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)46(44,45)39-30(42)24-10-8-19-37-29(24)33/h4-13,15-19H,2-3,14,20H2,1H3,(H,39,42) DZQVFTZIXNLOIV-UHFFFAOYSA-N 50039935 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-chloro-pyridine-3-carbonyl)-amide::CHEMBL317864 Type-1 angiotensin II receptor Oryctolagus cuniculus 1 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039935 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039935&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417031 103947130 CHEMBL317864 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036485 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H24F3N7O/c1-2-3-12-24-33-37(23-11-7-6-10-22(23)27(28,29)30)26(38)36(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-31-34-35-32-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,31,32,34,35) DWXCNNUZEBMCMR-UHFFFAOYSA-N 50035431 5-Butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2-trifluoromethyl-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2-trifluoromethyl-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL19018 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.780000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035431&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956757 103943450 CHEMBL19018 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036486 CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C32H27F3N4O4S/c1-2-10-29-36-39(27-15-8-7-14-26(27)32(33,34)35)31(41)38(29)21-22-17-19-23(20-18-22)25-13-6-9-16-28(25)44(42,43)37-30(40)24-11-4-3-5-12-24/h3-9,11-20H,2,10,21H2,1H3,(H,37,40) MWQZMWPNCFKLSS-UHFFFAOYSA-N 50039873 4'-[5-Oxo-3-propyl-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL97295 Type-1 angiotensin II receptor Oryctolagus cuniculus 13 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039873 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039873&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416422 103947068 CHEMBL97295 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036487 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1NS(=O)(=O)C(F)(F)F InChI=1S/C27H24F6N4O3S/c1-2-3-12-24-34-37(23-11-7-5-9-21(23)26(28,29)30)25(38)36(24)17-18-13-15-19(16-14-18)20-8-4-6-10-22(20)35-41(39,40)27(31,32)33/h4-11,13-16,35H,2-3,12,17H2,1H3 OWGRILLFWDIDSB-UHFFFAOYSA-N 50039892 N-{4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-yl}-C,C,C-trifluoro-methanesulfonamide::CHEMBL330007 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.8 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039892 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039892&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10100074 103947087 CHEMBL330007 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036488 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(F)(F)F InChI=1S/C28H24F6N4O4S/c1-2-3-12-24-35-38(22-10-6-5-9-21(22)27(29,30)31)26(40)37(24)17-18-13-15-19(16-14-18)20-8-4-7-11-23(20)43(41,42)36-25(39)28(32,33)34/h4-11,13-16H,2-3,12,17H2,1H3,(H,36,39) MIKVDFTVMKFWBK-UHFFFAOYSA-N 50039928 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2,2-trifluoro-acetyl)-amide::CHEMBL329759 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.800000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039928 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039928&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416501 103947123 CHEMBL329759 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036489 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(C)C InChI=1S/C30H31F3N4O4S/c1-4-5-14-27-34-37(25-12-8-7-11-24(25)30(31,32)33)29(39)36(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)42(40,41)35-28(38)20(2)3/h6-13,15-18,20H,4-5,14,19H2,1-3H3,(H,35,38) GWEIZWXOSOXGRV-UHFFFAOYSA-N 50039896 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid isobutyryl-amide::CHEMBL94910 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.800000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039896 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039896&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10483726 103947091 CHEMBL94910 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036490 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCOC1 InChI=1S/C31H31F3N4O5S/c1-2-3-12-28-35-38(26-10-6-5-9-25(26)31(32,33)34)30(40)37(28)19-21-13-15-22(16-14-21)24-8-4-7-11-27(24)44(41,42)36-29(39)23-17-18-43-20-23/h4-11,13-16,23H,2-3,12,17-20H2,1H3,(H,36,39) HSXNIXKCCIQHQC-UHFFFAOYSA-N 50039918 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (tetrahydro-furan-3-carbonyl)-amide::CHEMBL97812 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.8 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039918 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039918&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349029 103947113 CHEMBL97812 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036491 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCO1 InChI=1S/C31H31F3N4O5S/c1-2-3-14-28-35-38(25-11-6-5-10-24(25)31(32,33)34)30(40)37(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)44(41,42)36-29(39)26-12-8-19-43-26/h4-7,9-11,13,15-18,26H,2-3,8,12,14,19-20H2,1H3,(H,36,39) DUUNHXVRQNGIPB-UHFFFAOYSA-N 50039886 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (tetrahydro-furan-2-carbonyl)-amide::CHEMBL319404 Type-1 angiotensin II receptor Oryctolagus cuniculus 4.3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039886 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039886&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10031920 103947081 CHEMBL319404 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036492 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(N)(=O)=O InChI=1S/C25H25ClN4O3S/c1-2-3-12-24-28-30(22-10-6-5-9-21(22)26)25(31)29(24)17-18-13-15-19(16-14-18)20-8-4-7-11-23(20)34(27,32)33/h4-11,13-16H,2-3,12,17H2,1H3,(H2,27,32,33) SWBXYUQNJFSFPV-UHFFFAOYSA-N 50039908 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid amide::CHEMBL97783 Type-1 angiotensin II receptor Oryctolagus cuniculus 820 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039908 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039908&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10028815 103947103 CHEMBL97783 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036493 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1SCCS1 InChI=1S/C30H29F3N4O4S3/c1-2-3-12-26-34-37(24-10-6-5-9-23(24)30(31,32)33)29(39)36(26)19-20-13-15-21(16-14-20)22-8-4-7-11-25(22)44(40,41)35-27(38)28-42-17-18-43-28/h4-11,13-16,28H,2-3,12,17-19H2,1H3,(H,35,38) HUJNWEJMPLYWRR-UHFFFAOYSA-N 50039894 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid ([1,3]dithiolane-2-carbonyl)-amide::CHEMBL97394 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.350000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039894 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039894&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10032342 103947089 CHEMBL97394 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036494 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(Cl)ccc1Cl InChI=1S/C33H27Cl2F3N4O4S/c1-2-3-12-30-39-42(28-10-6-5-9-26(28)33(36,37)38)32(44)41(30)20-21-13-15-22(16-14-21)24-8-4-7-11-29(24)47(45,46)40-31(43)25-19-23(34)17-18-27(25)35/h4-11,13-19H,2-3,12,20H2,1H3,(H,40,43) KNTYZUJZCJPYJF-UHFFFAOYSA-N 50039883 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2,5-dichloro-benzoylamide::CHEMBL329942 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.480000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039883 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039883&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10009968 103947078 CHEMBL329942 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036495 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Br InChI=1S/C33H28BrF3N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42) PGSBRAGBLSJPGR-UHFFFAOYSA-N 50039863 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-bromo-benzoylamide::CHEMBL97020 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.400000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039863 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039863&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10010047 103947058 CHEMBL97020 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036496 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1C(F)(F)F InChI=1S/C34H28F6N4O4S/c1-2-3-16-30-41-44(28-14-8-7-13-27(28)34(38,39)40)32(46)43(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)49(47,48)42-31(45)25-11-4-6-12-26(25)33(35,36)37/h4-15,17-20H,2-3,16,21H2,1H3,(H,42,45) GOORPKDJWMFHLB-UHFFFAOYSA-N 50039926 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-trifluoromethyl-benzoylamide::CHEMBL407919 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.270000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039926 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039926&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055534 103947121 CHEMBL407919 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036497 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(cc1)C(F)(F)F InChI=1S/C34H28F6N4O4S/c1-2-3-12-30-41-44(28-10-6-5-9-27(28)34(38,39)40)32(46)43(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)49(47,48)42-31(45)24-17-19-25(20-18-24)33(35,36)37/h4-11,13-20H,2-3,12,21H2,1H3,(H,42,45) XGKFJRTZCJHJJY-UHFFFAOYSA-N 50039920 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-trifluoromethyl-benzoylamide::CHEMBL328176 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.8 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039920 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039920&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349791 103947115 CHEMBL328176 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036498 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1C InChI=1S/C34H31F3N4O4S/c1-3-4-17-31-38-41(29-15-9-8-14-28(29)34(35,36)37)33(43)40(31)22-24-18-20-25(21-19-24)27-13-7-10-16-30(27)46(44,45)39-32(42)26-12-6-5-11-23(26)2/h5-16,18-21H,3-4,17,22H2,1-2H3,(H,39,42) VFMXOJKKIIXTLB-UHFFFAOYSA-N 50039941 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-methyl-benzoylamide::CHEMBL330165 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.560000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039941 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039941&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10258694 103947136 CHEMBL330165 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036499 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C InChI=1S/C31H33F3N4O5S/c1-5-6-15-27-35-38(25-13-9-8-12-24(25)31(32,33)34)29(40)37(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)44(41,42)36-28(39)43-30(2,3)4/h7-14,16-19H,5-6,15,20H2,1-4H3,(H,36,39) IVFMKMCSJZZCKV-UHFFFAOYSA-N 50035451 4'-[3-Butyl-5-oxo-1-(2-trifluoromet hyl-phenyl)-15-dihydro-[124]tria zol-4-ylmethyl]-biphenyl-2-sulfonic acid t-butyloxycarbonylamide (L-162234)::L-162234::5-n-Butyl-4-[[2'-[N-(tert-butoxycarbonyl)sulfamoyl]biphenyl-4yl]methyl]-2-[2-trifluoromethyl-phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one::4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-tert-butoxycarbonyl)amide::4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid amide-N-carbonyoxylterbutyl::2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-t-butoxycarbonyl)benzenesulfonamide::CHEMBL292150 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.450000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035451&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9830680 103943470 CHEMBL292150 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036500 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc2ccccc2o1 InChI=1S/C35H29F3N4O5S/c1-2-3-16-32-39-42(28-13-7-6-12-27(28)35(36,37)38)34(44)41(32)22-23-17-19-24(20-18-23)26-11-5-9-15-31(26)48(45,46)40-33(43)30-21-25-10-4-8-14-29(25)47-30/h4-15,17-21H,2-3,16,22H2,1H3,(H,40,43) SGYXRZTXQJMDGN-UHFFFAOYSA-N 50039887 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (benzofuran-2-carbonyl)-amide; compound with ethoxy-ethane::CHEMBL98068 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.170000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039887 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039887&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10258974 103947082 CHEMBL98068 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036501 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1occ(Cl)c1Cl InChI=1S/C31H25Cl2F3N4O5S/c1-2-3-12-26-37-40(24-10-6-5-9-22(24)31(34,35)36)30(42)39(26)17-19-13-15-20(16-14-19)21-8-4-7-11-25(21)46(43,44)38-29(41)28-27(33)23(32)18-45-28/h4-11,13-16,18H,2-3,12,17H2,1H3,(H,38,41) DOUAJXVODABWRT-UHFFFAOYSA-N 50039930 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3,4-dichloro-furan-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL329290 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.190000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039930 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039930&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078397 103947125 CHEMBL329290 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036502 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1oc2ccccc2c1C InChI=1S/C36H31F3N4O5S/c1-3-4-17-32-40-43(29-14-8-7-13-28(29)36(37,38)39)35(45)42(32)22-24-18-20-25(21-19-24)27-12-6-10-16-31(27)49(46,47)41-34(44)33-23(2)26-11-5-9-15-30(26)48-33/h5-16,18-21H,3-4,17,22H2,1-2H3,(H,41,44) OLBYJPCOVQMYSH-UHFFFAOYSA-N 50039877 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methyl-benzofuran-2-carbonyl)-amide::CHEMBL327988 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.430000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039877 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039877&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349659 103947072 CHEMBL327988 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036503 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(C)s1 InChI=1S/C32H29F3N4O4S2/c1-3-4-13-29-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(29)20-22-15-17-23(18-16-22)24-9-5-8-12-28(24)45(42,43)37-30(40)27-19-14-21(2)44-27/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) JYZLVNVGBRFRME-UHFFFAOYSA-N 50039855 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-methyl-thiophene-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL265012 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.640000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039855 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039855&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 5312129 103947050 CHEMBL265012 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036504 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccc(c1)C(F)(F)F InChI=1S/C34H28F6N4O4S/c1-2-3-15-30-41-44(28-13-6-5-12-27(28)34(38,39)40)32(46)43(30)21-22-16-18-23(19-17-22)26-11-4-7-14-29(26)49(47,48)42-31(45)24-9-8-10-25(20-24)33(35,36)37/h4-14,16-20H,2-3,15,21H2,1H3,(H,42,45) GFFCZDIKQXMLDH-UHFFFAOYSA-N 50039912 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 3-trifluoromethyl-benzoylamide::CHEMBL317061 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039912 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039912&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078452 103947107 CHEMBL317061 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036505 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1OC InChI=1S/C34H31F3N4O5S/c1-3-4-17-31-38-41(28-14-8-7-13-27(28)34(35,36)37)33(43)40(31)22-23-18-20-24(21-19-23)25-11-6-10-16-30(25)47(44,45)39-32(42)26-12-5-9-15-29(26)46-2/h5-16,18-21H,3-4,17,22H2,1-2H3,(H,39,42) AZFWKIXDPPZMAV-UHFFFAOYSA-N 50039903 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-methoxy-benzoylamide::CHEMBL316904 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.410000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039903 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039903&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078132 103947098 CHEMBL316904 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036506 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1sccc1Br InChI=1S/C31H26BrF3N4O4S2/c1-2-3-12-27-36-39(25-10-6-5-9-23(25)31(33,34)35)30(41)38(27)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)28-24(32)17-18-44-28/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) GUIPGOBVMNVLJL-UHFFFAOYSA-N 50039879 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-bromo-thiophene-2-carbonyl)-amide::CHEMBL321363 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.720000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039879 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039879&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417431 103947074 CHEMBL321363 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036507 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(cc1)C#N InChI=1S/C34H28F3N5O4S/c1-2-3-12-31-39-42(29-10-6-5-9-28(29)34(35,36)37)33(44)41(31)22-24-15-17-25(18-16-24)27-8-4-7-11-30(27)47(45,46)40-32(43)26-19-13-23(21-38)14-20-26/h4-11,13-20H,2-3,12,22H2,1H3,(H,40,43) NREVODYWGRCNEM-UHFFFAOYSA-N 50039897 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-cyano-benzoylamide::CHEMBL97557 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.760000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039897 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039897&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349392 103947092 CHEMBL97557 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036508 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1sccc1C InChI=1S/C32H29F3N4O4S2/c1-3-4-13-28-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(28)20-22-14-16-23(17-15-22)24-9-5-8-12-27(24)45(42,43)37-30(40)29-21(2)18-19-44-29/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) MMDNKTXNUZFVKD-UHFFFAOYSA-N 50039902 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methyl-thiophene-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL97688 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.810000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039902 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039902&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9961192 103947097 CHEMBL97688 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036509 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(Cl)s1 InChI=1S/C31H26ClF3N4O4S2/c1-2-3-12-28-36-39(24-10-6-5-9-23(24)31(33,34)35)30(41)38(28)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)25-17-18-27(32)44-25/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) VCOPVBDJBRVQSW-UHFFFAOYSA-N 50039871 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-chloro-thiophene-2-carbonyl)-amide::CHEMBL433375 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039871&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372341 103947066 CHEMBL433375 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036510 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(C)oc1C InChI=1S/C33H31F3N4O5S/c1-4-5-14-30-37-40(28-12-8-7-11-27(28)33(34,35)36)32(42)39(30)20-23-15-17-24(18-16-23)25-10-6-9-13-29(25)46(43,44)38-31(41)26-19-21(2)45-22(26)3/h6-13,15-19H,4-5,14,20H2,1-3H3,(H,38,41) RDCONBROTQSADP-UHFFFAOYSA-N 50039900 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,5-dimethyl-furan-3-carbonyl)-amide::CHEMBL329255 Type-1 angiotensin II receptor Oryctolagus cuniculus 1 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039900 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039900&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439253 103947095 CHEMBL329255 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036511 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(C)oc1C(F)(F)F InChI=1S/C33H28F6N4O5S/c1-3-4-13-28-40-43(26-11-7-6-10-25(26)32(34,35)36)31(45)42(28)19-21-14-16-22(17-15-21)23-9-5-8-12-27(23)49(46,47)41-30(44)24-18-20(2)48-29(24)33(37,38)39/h5-12,14-18H,3-4,13,19H2,1-2H3,(H,41,44) BNFFMFZFKZQWDG-UHFFFAOYSA-N 50039882 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-methyl-2-trifluoromethyl-furan-3-carbonyl)-amide::CHEMBL97075 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.170000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039882 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039882&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417351 103947077 CHEMBL97075 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036512 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NS(=O)(=O)C(C)C InChI=1S/C29H31F3N4O5S2/c1-4-5-14-27-33-36(25-12-8-7-11-24(25)29(30,31)32)28(37)35(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)43(40,41)34-42(38,39)20(2)3/h6-13,15-18,20,34H,4-5,14,19H2,1-3H3 NGRWJNOGBNJYQQ-UHFFFAOYSA-N 50039929 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-isopropylaminosulphonyl)benzenesulfonamide::CHEMBL316706 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.160000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039929 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039929&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10009273 103947124 CHEMBL316706 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036513 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccoc1C InChI=1S/C32H29F3N4O5S/c1-3-4-13-29-36-39(27-11-7-6-10-26(27)32(33,34)35)31(41)38(29)20-22-14-16-23(17-15-22)25-9-5-8-12-28(25)45(42,43)37-30(40)24-18-19-44-21(24)2/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) CJGZUWKIXNNPQK-UHFFFAOYSA-N 50039881 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-methyl-furan-3-carbonyl)-amide::CHEMBL95198 Type-1 angiotensin II receptor Oryctolagus cuniculus 3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039881 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039881&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10233073 103947076 CHEMBL95198 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036514 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccn1C InChI=1S/C32H30F3N5O4S/c1-3-4-15-29-36-40(26-12-7-6-11-25(26)32(33,34)35)31(42)39(29)21-22-16-18-23(19-17-22)24-10-5-8-14-28(24)45(43,44)37-30(41)27-13-9-20-38(27)2/h5-14,16-20H,3-4,15,21H2,1-2H3,(H,37,41) MDWZSHJNBJBDCC-UHFFFAOYSA-N 50039934 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (1-methyl-1H-pyrrole-2-carbonyl)-amide::CHEMBL316297 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.6 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039934 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039934&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10233056 103947129 CHEMBL316297 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036515 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccoc1 InChI=1S/C31H27F3N4O5S/c1-2-3-12-28-35-38(26-10-6-5-9-25(26)31(32,33)34)30(40)37(28)19-21-13-15-22(16-14-21)24-8-4-7-11-27(24)44(41,42)36-29(39)23-17-18-43-20-23/h4-11,13-18,20H,2-3,12,19H2,1H3,(H,36,39) XGHGJYYEMSDPFJ-UHFFFAOYSA-N 50039911 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (furan-3-carbonyl)-amide::CHEMBL97964 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.9 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039911 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039911&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10461595 103947106 CHEMBL97964 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036516 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NS(=O)(=O)c1ccccc1 InChI=1S/C32H29F3N4O5S2/c1-2-3-17-30-36-39(28-15-9-8-14-27(28)32(33,34)35)31(40)38(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)46(43,44)37-45(41,42)25-11-5-4-6-12-25/h4-16,18-21,37H,2-3,17,22H2,1H3 FISKGPNVOMOSRW-UHFFFAOYSA-N 50039895 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-phenylsulphonyl)benzenesulfonamide::CHEMBL97332 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.200000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039895 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039895&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349512 103947090 CHEMBL97332 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036517 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1ccc(cc1)[N+]([O-])=O InChI=1S/C32H28F3N5O5S/c1-2-3-12-30-36-39(28-10-6-5-9-27(28)32(33,34)35)31(41)38(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)46(44,45)37-24-17-19-25(20-18-24)40(42)43/h4-11,13-20,37H,2-3,12,21H2,1H3 IQQZEYOKQKUIOY-UHFFFAOYSA-N 50039866 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (4-nitro-phenyl)-amide::CHEMBL319313 Type-1 angiotensin II receptor Oryctolagus cuniculus 78 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039866 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039866&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416836 103947061 CHEMBL319313 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036518 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1C2CCC(C2)C1=C |TLB:37:39:44:41.42,THB:46:45:44:41.42| 50039865 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methylene-bicyclo[2.2.1]heptane-2-carbonyl)-amide::CHEMBL330464 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.390000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039865 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039865&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328276 103947060 CHEMBL330464 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036519 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CC(C)(C)C InChI=1S/C32H35F3N4O4S/c1-5-6-15-28-36-39(26-13-9-8-12-25(26)32(33,34)35)30(41)38(28)21-22-16-18-23(19-17-22)24-11-7-10-14-27(24)44(42,43)37-29(40)20-31(2,3)4/h7-14,16-19H,5-6,15,20-21H2,1-4H3,(H,37,40) RZHQBDADSKJDGW-UHFFFAOYSA-N 50039906 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3,3-dimethyl-butyryl)-amide::CHEMBL432822 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.1 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039906 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039906&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10484119 103947101 CHEMBL432822 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036520 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccco1 InChI=1S/C31H27F3N4O5S/c1-2-3-14-28-35-38(25-11-6-5-10-24(25)31(32,33)34)30(40)37(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)44(41,42)36-29(39)26-12-8-19-43-26/h4-13,15-19H,2-3,14,20H2,1H3,(H,36,39) OQYLAHYLTMNIEX-UHFFFAOYSA-N 50039922 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (furan-2-carbonyl)-amide::CHEMBL95579 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.260000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039922 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039922&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416475 103947117 CHEMBL95579 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036521 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(F)(F)F InChI=1S/C27H24ClF3N4O4S/c1-2-3-12-24-32-35(22-10-6-5-9-21(22)28)26(37)34(24)17-18-13-15-19(16-14-18)20-8-4-7-11-23(20)40(38,39)33-25(36)27(29,30)31/h4-11,13-16H,2-3,12,17H2,1H3,(H,33,36) ACIJKSZKWJVCPE-UHFFFAOYSA-N 50039891 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2,2-trifluoro-acetyl)-amide::CHEMBL94582 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.1 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039891 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039891&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054188 103947086 CHEMBL94582 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036522 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1sccc1Cl InChI=1S/C31H26ClF3N4O4S2/c1-2-3-12-27-36-39(25-10-6-5-9-23(25)31(33,34)35)30(41)38(27)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)28-24(32)17-18-44-28/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) KJDIKXLNGXMGRU-UHFFFAOYSA-N 50039885 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-chloro-thiophene-2-carbonyl)-amide::CHEMBL97446 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.270000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039885 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039885&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9875044 103947080 CHEMBL97446 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036523 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(OC)cc1 InChI=1S/C34H31F3N4O5S/c1-3-4-13-31-38-41(29-11-7-6-10-28(29)34(35,36)37)33(43)40(31)22-23-14-16-24(17-15-23)27-9-5-8-12-30(27)47(44,45)39-32(42)25-18-20-26(46-2)21-19-25/h5-12,14-21H,3-4,13,22H2,1-2H3,(H,39,42) CKSULLXPURNTFN-UHFFFAOYSA-N 50039859 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-methoxy-benzoylamide::CHEMBL330463 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.740000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039859 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039859&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10032361 103947054 CHEMBL330463 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036524 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1-c1ccccc1 InChI=1S/C39H33F3N4O4S/c1-2-3-21-36-43-46(34-19-11-10-18-33(34)39(40,41)42)38(48)45(36)26-27-22-24-29(25-23-27)31-16-9-12-20-35(31)51(49,50)44-37(47)32-17-8-7-15-30(32)28-13-5-4-6-14-28/h4-20,22-25H,2-3,21,26H2,1H3,(H,44,47) LDVDMGJMFCRHCA-UHFFFAOYSA-N 50039884 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (biphenyl-2-carbonyl)-amide::CHEMBL97465 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.600000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039884 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039884&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10010027 103947079 CHEMBL97465 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036525 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccc(Cl)c1Cl InChI=1S/C33H27Cl2F3N4O4S/c1-2-3-15-29-39-42(27-13-6-5-11-25(27)33(36,37)38)32(44)41(29)20-21-16-18-22(19-17-21)23-9-4-7-14-28(23)47(45,46)40-31(43)24-10-8-12-26(34)30(24)35/h4-14,16-19H,2-3,15,20H2,1H3,(H,40,43) LQLOVKYYMGPNEF-UHFFFAOYSA-N 50039943 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2,3-dichloro-benzoylamide::CHEMBL319353 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.720000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039943 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039943&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349801 103947138 CHEMBL319353 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036526 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1c(C)cccc1C InChI=1S/C35H33F3N4O4S/c1-4-5-17-31-39-42(29-15-8-7-14-28(29)35(36,37)38)34(44)41(31)22-25-18-20-26(21-19-25)27-13-6-9-16-30(27)47(45,46)40-33(43)32-23(2)11-10-12-24(32)3/h6-16,18-21H,4-5,17,22H2,1-3H3,(H,40,43) KFZJBZUZBZQWGB-UHFFFAOYSA-N 50039944 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2,6-dimethyl-benzoylamide::CHEMBL327791 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.9 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039944 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039944&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416957 103947139 CHEMBL327791 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036527 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(c1ccccc1)c1ccccc1 InChI=1S/C40H35F3N4O4S/c1-2-3-22-36-44-47(34-20-12-11-19-33(34)40(41,42)43)39(49)46(36)27-28-23-25-29(26-24-28)32-18-10-13-21-35(32)52(50,51)45-38(48)37(30-14-6-4-7-15-30)31-16-8-5-9-17-31/h4-21,23-26,37H,2-3,22,27H2,1H3,(H,45,48) WFPJYSLLXXXCLR-UHFFFAOYSA-N 50039932 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid diphenylacetyl-amide::CHEMBL317368 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.8 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039932 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039932&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372723 103947127 CHEMBL317368 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036528 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCC1CCCC1 InChI=1S/C34H37F3N4O4S/c1-2-3-16-31-38-41(29-14-8-7-13-28(29)34(35,36)37)33(43)40(31)23-25-17-20-26(21-18-25)27-12-6-9-15-30(27)46(44,45)39-32(42)22-19-24-10-4-5-11-24/h6-9,12-15,17-18,20-21,24H,2-5,10-11,16,19,22-23H2,1H3,(H,39,42) NIOFBGYJFARBSF-UHFFFAOYSA-N 50039851 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-cyclopentyl-propionyl)-amide::CHEMBL314514 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.2 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039851 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039851&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078048 103947046 CHEMBL314514 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036529 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl InChI=1S/C33H28ClF3N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42) FNGNUUQIAIQKKJ-UHFFFAOYSA-N 50035445 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-chloro-benzoylamide::CHEMBL316300 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.110000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035445 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035445&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809961 103943464 CHEMBL316300 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036530 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cc1ccccc1 InChI=1S/C40H35F3N4O4S/c1-2-3-21-37-44-47(35-19-11-10-18-34(35)40(41,42)43)39(49)46(37)27-29-22-24-30(25-23-29)32-16-9-12-20-36(32)52(50,51)45-38(48)33-17-8-7-15-31(33)26-28-13-5-4-6-14-28/h4-20,22-25H,2-3,21,26-27H2,1H3,(H,45,48) DGADYUCYHDLBMN-UHFFFAOYSA-N 50039940 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-benzyl-benzoylamide::CHEMBL97464 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.820000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039940 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039940&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10010125 103947135 CHEMBL97464 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036531 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NC(C)C InChI=1S/C30H32F3N5O4S/c1-4-5-14-27-35-38(25-12-8-7-11-24(25)30(31,32)33)29(40)37(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)43(41,42)36-28(39)34-20(2)3/h6-13,15-18,20H,4-5,14,19H2,1-3H3,(H2,34,36,39) HEHVZBBAYSZOSP-UHFFFAOYSA-N 50039937 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-isopropylaminocarbonyl)benzenesulfonamide::CHEMBL330170 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.1 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039937 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039937&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10348847 103947132 CHEMBL330170 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036532 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(Br)sc1Br InChI=1S/C31H25Br2F3N4O4S2/c1-2-3-12-27-37-40(24-10-6-5-9-23(24)31(34,35)36)30(42)39(27)18-19-13-15-20(16-14-19)21-8-4-7-11-25(21)46(43,44)38-29(41)22-17-26(32)45-28(22)33/h4-11,13-17H,2-3,12,18H2,1H3,(H,38,41) CQHRAIJPPWOOSU-UHFFFAOYSA-N 50039852 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,5-dibromo-thiophene-3-carbonyl)-amide::CHEMBL98453 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.670000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039852 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039852&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10350378 103947047 CHEMBL98453 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036533 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCC1 InChI=1S/C31H31F3N4O4S/c1-2-3-15-28-35-38(26-13-6-5-12-25(26)31(32,33)34)30(40)37(28)20-21-16-18-22(19-17-21)24-11-4-7-14-27(24)43(41,42)36-29(39)23-9-8-10-23/h4-7,11-14,16-19,23H,2-3,8-10,15,20H2,1H3,(H,36,39) RIUAOEISGORHGS-UHFFFAOYSA-N 50039917 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclobutanecarbonyl-amide; compound with trichloro-methane::CHEMBL98426 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.840000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039917 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039917&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077497 103947112 CHEMBL98426 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036534 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1 InChI=1S/C30H29F3N4O4S/c1-2-3-12-27-34-37(25-10-6-5-9-24(25)30(31,32)33)29(39)36(27)19-20-13-15-21(16-14-20)23-8-4-7-11-26(23)42(40,41)35-28(38)22-17-18-22/h4-11,13-16,22H,2-3,12,17-19H2,1H3,(H,35,38) JTGPQJDOJHLOHY-UHFFFAOYSA-N 50039901 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclopropanecarbonyl-amide::CHEMBL98126 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.5 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039901 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039901&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10438523 103947096 CHEMBL98126 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036535 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(Cl)sc1Cl InChI=1S/C31H25Cl2F3N4O4S2/c1-2-3-12-27-37-40(24-10-6-5-9-23(24)31(34,35)36)30(42)39(27)18-19-13-15-20(16-14-19)21-8-4-7-11-25(21)46(43,44)38-29(41)22-17-26(32)45-28(22)33/h4-11,13-17H,2-3,12,18H2,1H3,(H,38,41) IXSJGZOXWQGYRR-UHFFFAOYSA-N 50039861 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,5-dichloro-thiophene-3-carbonyl)-amide; compound with dichloro-methane::CHEMBL97271 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.6 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039861 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039861&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349845 103947056 CHEMBL97271 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036536 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc2ccccc2s1 InChI=1S/C35H29F3N4O4S2/c1-2-3-16-32-39-42(28-13-7-6-12-27(28)35(36,37)38)34(44)41(32)22-23-17-19-24(20-18-23)26-11-5-9-15-31(26)48(45,46)40-33(43)30-21-25-10-4-8-14-29(25)47-30/h4-15,17-21H,2-3,16,22H2,1H3,(H,40,43) SIEOBZYPHMFGHF-UHFFFAOYSA-N 50039938 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (benzo[b]thiophene-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL411487 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.310000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039938 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039938&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10032583 103947133 CHEMBL411487 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036537 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(C)(C)C InChI=1S/C29H33ClN4O3S/c1-5-6-15-27-31-34(25-13-9-8-12-24(25)30)28(35)33(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)38(36,37)32-29(2,3)4/h7-14,16-19,32H,5-6,15,20H2,1-4H3 YRHWEGNWYOPJSQ-UHFFFAOYSA-N 50039907 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid tert-butylamide::CHEMBL97273 Type-1 angiotensin II receptor Oryctolagus cuniculus 1300 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039907 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039907&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 11757357 103947102 CHEMBL97273 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036538 CCCCc1nn(CC(C)(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C31H36N4O4S/c1-5-6-16-28-32-35(22-31(2,3)4)30(37)34(28)21-23-17-19-24(20-18-23)26-14-10-11-15-27(26)40(38,39)33-29(36)25-12-8-7-9-13-25/h7-15,17-20H,5-6,16,21-22H2,1-4H3,(H,33,36) GHBYHMXNLNDBNI-UHFFFAOYSA-N 50039925 CHEMBL429058::4''-[3-Butyl-1-(2,2-dimethyl-propyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide; compound with dichloro-methane::CHEMBL321086 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039925 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039925&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10482937 103947120 CHEMBL321086CHEMBL429058 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036539 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C32H29ClN4O4S/c1-2-3-17-30-34-37(28-15-9-8-14-27(28)33)32(39)36(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)42(40,41)35-31(38)25-11-5-4-6-12-25/h4-16,18-21H,2-3,17,22H2,1H3,(H,35,38) LEOPIANEXZTGSQ-UHFFFAOYSA-N 50039888 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL275160 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.4 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039888 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039888&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054324 103947083 CHEMBL275160 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036540 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NC(C)(C)C InChI=1S/C31H34F3N5O4S/c1-5-6-15-27-36-39(25-13-9-8-12-24(25)31(32,33)34)29(41)38(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)44(42,43)37-28(40)35-30(2,3)4/h7-14,16-19H,5-6,15,20H2,1-4H3,(H2,35,37,40) WZKRVEFOLSRJOQ-UHFFFAOYSA-N 50039890 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-t-butylaminocarbonyl)benzenesulfonamide::CHEMBL98140 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.6 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039890 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039890&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054753 103947085 CHEMBL98140 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036541 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC#N InChI=1S/C27H24F3N5O3S/c1-2-3-12-25-33-35(23-10-6-5-9-22(23)27(28,29)30)26(36)34(25)17-19-13-15-20(16-14-19)21-8-4-7-11-24(21)39(37,38)32-18-31/h4-11,13-16,32H,2-3,12,17H2,1H3 JGMCHTAMZJGMIP-UHFFFAOYSA-N 50039910 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-cyano)benzenesulfonamide::CHEMBL94407 Type-1 angiotensin II receptor Oryctolagus cuniculus 4.7 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039910 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039910&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10460346 103947105 CHEMBL94407 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036542 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1(C)C InChI=1S/C32H33F3N4O4S/c1-4-5-14-28-36-39(26-12-8-7-11-24(26)32(33,34)35)30(41)38(28)20-21-15-17-22(18-16-21)23-10-6-9-13-27(23)44(42,43)37-29(40)25-19-31(25,2)3/h6-13,15-18,25H,4-5,14,19-20H2,1-3H3,(H,37,40) SJGJRWCAQBHZQD-UHFFFAOYSA-N 50039853 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-dimethyl-cyclopropanecarbonyl)-amide::CHEMBL317547 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.360000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039853 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039853&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 19939398 103947048 CHEMBL317547 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036543 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1C(C)(C)C1(C)C InChI=1S/C34H37F3N4O4S/c1-6-7-16-28-38-41(26-14-10-9-13-25(26)34(35,36)37)31(43)40(28)21-22-17-19-23(20-18-22)24-12-8-11-15-27(24)46(44,45)39-30(42)29-32(2,3)33(29,4)5/h8-15,17-20,29H,6-7,16,21H2,1-5H3,(H,39,42) QKLZIKJSBBMLRK-UHFFFAOYSA-N 50039945 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2,3,3-tetramethyl-cyclopropanecarbonyl)-amide::CHEMBL432392 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039945 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039945&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439275 103947140 CHEMBL432392 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036544 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccsc1 InChI=1S/C31H27F3N4O4S2/c1-2-3-12-28-35-38(26-10-6-5-9-25(26)31(32,33)34)30(40)37(28)19-21-13-15-22(16-14-21)24-8-4-7-11-27(24)44(41,42)36-29(39)23-17-18-43-20-23/h4-11,13-18,20H,2-3,12,19H2,1H3,(H,36,39) KFWPNELLKZVYGR-UHFFFAOYSA-N 50039876 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (thiophene-3-carbonyl)-amide::CHEMBL95197 Type-1 angiotensin II receptor Oryctolagus cuniculus 5 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039876 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039876&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054912 103947071 CHEMBL95197 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036545 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C33H29F3N4O4S/c1-2-3-17-30-37-40(28-15-9-8-14-27(28)33(34,35)36)32(42)39(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)45(43,44)38-31(41)25-11-5-4-6-12-25/h4-16,18-21H,2-3,17,22H2,1H3,(H,38,41) JVOGASLNIGJLLS-UHFFFAOYSA-N 50030727 L-159,913::CHEMBL97539::CHEMBL279629::4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::L-159913 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.430000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030727 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030727&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9939191 103939575 CHEMBL279629CHEMBL97539 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036546 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1(F)F InChI=1S/C30H27F5N4O4S/c1-2-3-12-26-36-39(24-10-6-5-9-22(24)30(33,34)35)28(41)38(26)18-19-13-15-20(16-14-19)21-8-4-7-11-25(21)44(42,43)37-27(40)23-17-29(23,31)32/h4-11,13-16,23H,2-3,12,17-18H2,1H3,(H,37,40) ULBQOFYLQNBFKK-UHFFFAOYSA-N 50039909 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-difluoro-cyclopropanecarbonyl)-amide::CHEMBL321367 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.640000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039909&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9874086 103947104 CHEMBL321367 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036547 FC(F)(F)CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl InChI=1S/C33H25ClF6N4O4S/c34-26-11-4-1-9-24(26)30(45)42-49(47,48)28-13-6-2-8-23(28)22-17-15-21(16-18-22)20-43-29(14-7-19-32(35,36)37)41-44(31(43)46)27-12-5-3-10-25(27)33(38,39)40/h1-6,8-13,15-18H,7,14,19-20H2,(H,42,45) CBIPYYSLZMYMPZ-UHFFFAOYSA-N 50039858 4'-[5-Oxo-3-(4,4,4-trifluoro-butyl)-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-chloro-benzoylamide::CHEMBL320222 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.360000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039858 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039858&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372718 103947053 CHEMBL320222 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036548 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccc(Cl)c1 InChI=1S/C33H28ClF3N4O4S/c1-2-3-15-30-38-41(28-13-6-5-12-27(28)33(35,36)37)32(43)40(30)21-22-16-18-23(19-17-22)26-11-4-7-14-29(26)46(44,45)39-31(42)24-9-8-10-25(34)20-24/h4-14,16-20H,2-3,15,21H2,1H3,(H,39,42) OSGLCHDZVVFCBG-UHFFFAOYSA-N 50039868 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 3-chloro-benzoylamide::CHEMBL97615 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.4 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039868 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039868&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349506 103947063 CHEMBL97615 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036549 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(Cl)cc1 InChI=1S/C33H28ClF3N4O4S/c1-2-3-12-30-38-41(28-10-6-5-9-27(28)33(35,36)37)32(43)40(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)46(44,45)39-31(42)24-17-19-25(34)20-18-24/h4-11,13-20H,2-3,12,21H2,1H3,(H,39,42) IKRYWDCWVGEVKU-UHFFFAOYSA-N 50039942 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-chloro-benzoylamide::CHEMBL95955 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.2 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039942 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039942&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9986951 103947137 CHEMBL95955 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036550 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(C)o1 InChI=1S/C32H29F3N4O5S/c1-3-4-13-29-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(29)20-22-15-17-23(18-16-22)24-9-5-8-12-28(24)45(42,43)37-30(40)27-19-14-21(2)44-27/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) GSICYOFDBGKLHW-UHFFFAOYSA-N 50039923 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-methyl-furan-2-carbonyl)-amide::CHEMBL329089 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.400000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039923 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039923&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326775 103947118 CHEMBL329089 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036551 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCCC(O)=O InChI=1S/C31H31F3N4O6S/c1-2-3-13-27-35-38(25-11-6-5-10-24(25)31(32,33)34)30(42)37(27)20-21-16-18-22(19-17-21)23-9-4-7-12-26(23)45(43,44)36-28(39)14-8-15-29(40)41/h4-7,9-12,16-19H,2-3,8,13-15,20H2,1H3,(H,36,39)(H,40,41) KDMXTHPIIMPHJG-UHFFFAOYSA-N 50039936 5-{4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonylamino}-5-oxo-pentanoic acid::CHEMBL94355 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.5 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039936 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039936&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439172 103947131 CHEMBL94355 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036552 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)COCC InChI=1S/C30H31F3N4O5S/c1-3-5-14-27-34-37(25-12-8-7-11-24(25)30(31,32)33)29(39)36(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)43(40,41)35-28(38)20-42-4-2/h6-13,15-18H,3-5,14,19-20H2,1-2H3,(H,35,38) KQJQNVZAJRKQLW-UHFFFAOYSA-N 50039889 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-ethoxy-acetyl)-amide::CHEMBL409058 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.750000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039889 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039889&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9986299 103947084 CHEMBL409058 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036553 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCCCCN InChI=1S/C32H36F3N5O4S/c1-2-3-15-29-37-40(27-13-8-7-12-26(27)32(33,34)35)31(42)39(29)22-23-17-19-24(20-18-23)25-11-6-9-14-28(25)45(43,44)38-30(41)16-5-4-10-21-36/h6-9,11-14,17-20H,2-5,10,15-16,21-22,36H2,1H3,(H,38,41) CBCSBEOTLXHMAV-UHFFFAOYSA-N 50039854 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (6-amino-hexanoyl)-amide::CHEMBL93606 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039854 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039854&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077929 103947049 CHEMBL93606 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036554 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)o1 InChI=1S/C31H26BrF3N4O5S/c1-2-3-12-28-36-39(24-10-6-5-9-23(24)31(33,34)35)30(41)38(28)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)25-17-18-27(32)44-25/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) WNYLIIWRLGEPDO-UHFFFAOYSA-N 50039913 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-bromo-furan-2-carbonyl)-amide::CHEMBL327191 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.400000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039913 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039913&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10394995 103947108 CHEMBL327191 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036555 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1oc(C)cc1C InChI=1S/C33H31F3N4O5S/c1-4-5-14-29-37-40(27-12-8-7-11-26(27)33(34,35)36)32(42)39(29)20-23-15-17-24(18-16-23)25-10-6-9-13-28(25)46(43,44)38-31(41)30-21(2)19-22(3)45-30/h6-13,15-19H,4-5,14,20H2,1-3H3,(H,38,41) AOOWLKVDPNXOHY-UHFFFAOYSA-N 50039899 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3,5-dimethyl-furan-2-carbonyl)-amide::CHEMBL329693 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.220000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039899 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039899&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326942 103947094 CHEMBL329693 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036556 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCOC InChI=1S/C30H31F3N4O5S/c1-3-4-13-27-34-37(25-11-7-6-10-24(25)30(31,32)33)29(39)36(27)20-21-14-16-22(17-15-21)23-9-5-8-12-26(23)43(40,41)35-28(38)18-19-42-2/h5-12,14-17H,3-4,13,18-20H2,1-2H3,(H,35,38) PPWHZKADGPDDCI-UHFFFAOYSA-N 50039931 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methoxy-propionyl)-amide::CHEMBL93956 Type-1 angiotensin II receptor Oryctolagus cuniculus 2 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039931 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039931&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077555 103947126 CHEMBL93956 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036557 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(C)(C)C InChI=1S/C31H33F3N4O4S/c1-5-6-15-27-35-38(25-13-9-8-12-24(25)31(32,33)34)29(40)37(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)43(41,42)36-28(39)30(2,3)4/h7-14,16-19H,5-6,15,20H2,1-4H3,(H,36,39) IOSUNMRKYMXORJ-UHFFFAOYSA-N 50039874 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-dimethyl-propionyl)-amide::CHEMBL97897 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.3 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039874 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039874&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326460 103947069 CHEMBL97897 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036558 CCCCc1nn(C(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C29H32N4O4S/c1-4-5-15-27-30-33(21(2)3)29(35)32(27)20-22-16-18-23(19-17-22)25-13-9-10-14-26(25)38(36,37)31-28(34)24-11-7-6-8-12-24/h6-14,16-19,21H,4-5,15,20H2,1-3H3,(H,31,34) WVYPOJYKXIHIOB-UHFFFAOYSA-N 50039905 4'-(3-Butyl-1-isopropyl-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl)-biphenyl-2-sulfonic acid benzoylamide::CHEMBL318891 Type-1 angiotensin II receptor Oryctolagus cuniculus 7 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039905 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039905&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10075750 103947100 CHEMBL318891 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50036559 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1C InChI=1S/C31H31F3N4O4S/c1-3-4-13-28-35-38(26-11-7-6-10-25(26)31(32,33)34)30(40)37(28)19-21-14-16-22(17-15-21)23-9-5-8-12-27(23)43(41,42)36-29(39)24-18-20(24)2/h5-12,14-17,20,24H,3-4,13,18-19H2,1-2H3,(H,36,39) KXYFGMIPNUPRJC-UHFFFAOYSA-N 50039867 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-methyl-cyclopropanecarbonyl)-amide::CHEMBL316655 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.560000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039867 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039867&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10438745 103947062 CHEMBL316655 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50062785 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCC1CCCC1 InChI=1S/C34H37F3N4O4S/c1-2-3-16-31-38-41(29-14-8-7-13-28(29)34(35,36)37)33(43)40(31)23-25-17-20-26(21-18-25)27-12-6-9-15-30(27)46(44,45)39-32(42)22-19-24-10-4-5-11-24/h6-9,12-15,17-18,20-21,24H,2-5,10-11,16,19,22-23H2,1H3,(H,39,42) NIOFBGYJFARBSF-UHFFFAOYSA-N 50039851 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-cyclopentyl-propionyl)-amide::CHEMBL314514 Type-2 angiotensin II receptor Rattus norvegicus 720 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039851 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039851&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078048 103947046 CHEMBL314514 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062788 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(C)s1 InChI=1S/C32H29F3N4O4S2/c1-3-4-13-29-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(29)20-22-15-17-23(18-16-22)24-9-5-8-12-28(24)45(42,43)37-30(40)27-19-14-21(2)44-27/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) JYZLVNVGBRFRME-UHFFFAOYSA-N 50039855 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-methyl-thiophene-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL265012 Type-2 angiotensin II receptor Rattus norvegicus 190 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039855 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039855&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 5312129 103947050 CHEMBL265012 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062789 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCCCCN InChI=1S/C32H36F3N5O4S/c1-2-3-15-29-37-40(27-13-8-7-12-26(27)32(33,34)35)31(42)39(29)22-23-17-19-24(20-18-23)25-11-6-9-14-28(25)45(43,44)38-30(41)16-5-4-10-21-36/h6-9,11-14,17-20H,2-5,10,15-16,21-22,36H2,1H3,(H,38,41) CBCSBEOTLXHMAV-UHFFFAOYSA-N 50039854 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (6-amino-hexanoyl)-amide::CHEMBL93606 Type-2 angiotensin II receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039854 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039854&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077929 103947049 CHEMBL93606 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062790 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1(C)C InChI=1S/C32H33F3N4O4S/c1-4-5-14-28-36-39(26-12-8-7-11-24(26)32(33,34)35)30(41)38(28)20-21-15-17-22(18-16-21)23-10-6-9-13-27(23)44(42,43)37-29(40)25-19-31(25,2)3/h6-13,15-18,25H,4-5,14,19-20H2,1-3H3,(H,37,40) SJGJRWCAQBHZQD-UHFFFAOYSA-N 50039853 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-dimethyl-cyclopropanecarbonyl)-amide::CHEMBL317547 Type-2 angiotensin II receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039853 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039853&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 19939398 103947048 CHEMBL317547 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062791 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCC InChI=1S/C29H29F3N4O5S/c1-3-5-14-26-33-36(24-12-8-7-11-23(24)29(30,31)32)28(38)35(26)19-20-15-17-21(18-16-20)22-10-6-9-13-25(22)42(39,40)34-27(37)41-4-2/h6-13,15-18H,3-5,14,19H2,1-2H3,(H,34,37) FSOKFDUOJSQIKR-UHFFFAOYSA-N 50039856 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-ethoxycarbonyl)benzenesulfonamide::CHEMBL431619 Type-2 angiotensin II receptor Rattus norvegicus 75 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039856 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039856&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10393837 103947051 CHEMBL431619 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062796 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Br InChI=1S/C33H28BrF3N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42) PGSBRAGBLSJPGR-UHFFFAOYSA-N 50039863 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-bromo-benzoylamide::CHEMBL97020 Type-2 angiotensin II receptor Rattus norvegicus 45 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039863 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039863&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10010047 103947058 CHEMBL97020 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062797 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(OC)cc1 InChI=1S/C34H31F3N4O5S/c1-3-4-13-31-38-41(29-11-7-6-10-28(29)34(35,36)37)33(43)40(31)22-23-14-16-24(17-15-23)27-9-5-8-12-30(27)47(44,45)39-32(42)25-18-20-26(46-2)21-19-25/h5-12,14-21H,3-4,13,22H2,1-2H3,(H,39,42) CKSULLXPURNTFN-UHFFFAOYSA-N 50039859 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-methoxy-benzoylamide::CHEMBL330463 Type-2 angiotensin II receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039859 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039859&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10032361 103947054 CHEMBL330463 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062798 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(F)cc1 InChI=1S/C33H28F4N4O4S/c1-2-3-12-30-38-41(28-10-6-5-9-27(28)33(35,36)37)32(43)40(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)46(44,45)39-31(42)24-17-19-25(34)20-18-24/h4-11,13-20H,2-3,12,21H2,1H3,(H,39,42) HZIBLUNQSCPVRC-UHFFFAOYSA-N 50039860 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-fluoro-benzoylamide::CHEMBL329858 Type-2 angiotensin II receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039860 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039860&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10009478 103947055 CHEMBL329858 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062800 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1C2CCC(C2)C1=C |TLB:37:39:44:41.42,THB:46:45:44:41.42| 50039865 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methylene-bicyclo[2.2.1]heptane-2-carbonyl)-amide::CHEMBL330464 Type-2 angiotensin II receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039865 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039865&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328276 103947060 CHEMBL330464 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062803 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1ccc(cc1)[N+]([O-])=O InChI=1S/C32H28F3N5O5S/c1-2-3-12-30-36-39(28-10-6-5-9-27(28)32(33,34)35)31(41)38(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)46(44,45)37-24-17-19-25(20-18-24)40(42)43/h4-11,13-20,37H,2-3,12,21H2,1H3 IQQZEYOKQKUIOY-UHFFFAOYSA-N 50039866 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (4-nitro-phenyl)-amide::CHEMBL319313 Type-2 angiotensin II receptor Rattus norvegicus 5200 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039866 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039866&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416836 103947061 CHEMBL319313 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062804 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)Cc1ccccc1 InChI=1S/C34H31F3N4O4S/c1-2-3-17-31-38-41(29-15-9-8-14-28(29)34(35,36)37)33(43)40(31)23-25-18-20-26(21-19-25)27-13-7-10-16-30(27)46(44,45)39-32(42)22-24-11-5-4-6-12-24/h4-16,18-21H,2-3,17,22-23H2,1H3,(H,39,42) HVIDQSDPDWZVHO-UHFFFAOYSA-N 50039872 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid phenylacetyl-amide::CHEMBL274710 Type-2 angiotensin II receptor Rattus norvegicus 240 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039872&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 11764826 103947067 CHEMBL274710 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062805 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1(C)CC1(Cl)Cl InChI=1S/C31H29Cl2F3N4O4S/c1-3-4-13-26-37-40(24-11-7-6-10-23(24)31(34,35)36)28(42)39(26)18-20-14-16-21(17-15-20)22-9-5-8-12-25(22)45(43,44)38-27(41)29(2)19-30(29,32)33/h5-12,14-17H,3-4,13,18-19H2,1-2H3,(H,38,41) RKRHFJADZOJHBH-UHFFFAOYSA-N 50039870 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-dichloro-1-methyl-cyclopropanecarbonyl)-amide::CHEMBL328434 Type-2 angiotensin II receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039870 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039870&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349597 103947065 CHEMBL328434 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062806 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(Cl)s1 InChI=1S/C31H26ClF3N4O4S2/c1-2-3-12-28-36-39(24-10-6-5-9-23(24)31(33,34)35)30(41)38(28)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)25-17-18-27(32)44-25/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) VCOPVBDJBRVQSW-UHFFFAOYSA-N 50039871 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-chloro-thiophene-2-carbonyl)-amide::CHEMBL433375 Type-2 angiotensin II receptor Rattus norvegicus 260 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039871&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372341 103947066 CHEMBL433375 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062807 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1nc2ccccc2o1 InChI=1S/C33H28F3N5O4S/c1-2-3-16-30-38-41(27-13-7-5-11-25(27)33(34,35)36)32(42)40(30)21-22-17-19-23(20-18-22)24-10-4-9-15-29(24)46(43,44)39-31-37-26-12-6-8-14-28(26)45-31/h4-15,17-20H,2-3,16,21H2,1H3,(H,37,39) BXRKFZIBTDBIGD-UHFFFAOYSA-N 50039869 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzooxazol-2-ylamide::CHEMBL327569 Type-2 angiotensin II receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039869 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039869&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349256 103947064 CHEMBL327569 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062809 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccsc1 InChI=1S/C31H27F3N4O4S2/c1-2-3-12-28-35-38(26-10-6-5-9-25(26)31(32,33)34)30(40)37(28)19-21-13-15-22(16-14-21)24-8-4-7-11-27(24)44(41,42)36-29(39)23-17-18-43-20-23/h4-11,13-18,20H,2-3,12,19H2,1H3,(H,36,39) KFWPNELLKZVYGR-UHFFFAOYSA-N 50039876 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (thiophene-3-carbonyl)-amide::CHEMBL95197 Type-2 angiotensin II receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039876 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039876&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054912 103947071 CHEMBL95197 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062810 CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C32H27F3N4O4S/c1-2-10-29-36-39(27-15-8-7-14-26(27)32(33,34)35)31(41)38(29)21-22-17-19-23(20-18-22)25-13-6-9-16-28(25)44(42,43)37-30(40)24-11-4-3-5-12-24/h3-9,11-20H,2,10,21H2,1H3,(H,37,40) MWQZMWPNCFKLSS-UHFFFAOYSA-N 50039873 4'-[5-Oxo-3-propyl-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL97295 Type-2 angiotensin II receptor Rattus norvegicus 520 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039873 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039873&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416422 103947068 CHEMBL97295 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062811 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(C)(C)C InChI=1S/C31H33F3N4O4S/c1-5-6-15-27-35-38(25-13-9-8-12-24(25)31(32,33)34)29(40)37(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)43(41,42)36-28(39)30(2,3)4/h7-14,16-19H,5-6,15,20H2,1-4H3,(H,36,39) IOSUNMRKYMXORJ-UHFFFAOYSA-N 50039874 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-dimethyl-propionyl)-amide::CHEMBL97897 Type-2 angiotensin II receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039874 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039874&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326460 103947069 CHEMBL97897 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062812 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1F InChI=1S/C33H28F4N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42) VQNOTIYWHVRPAM-UHFFFAOYSA-N 50039862 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-fluoro-benzoylamide::CHEMBL330533 Type-2 angiotensin II receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039862 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039862&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372093 103947057 CHEMBL330533 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062814 CC1CC1Cc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C34H29F3N4O4S/c1-22-19-26(22)20-31-38-41(29-13-7-6-12-28(29)34(35,36)37)33(43)40(31)21-23-15-17-24(18-16-23)27-11-5-8-14-30(27)46(44,45)39-32(42)25-9-3-2-4-10-25/h2-18,22,26H,19-21H2,1H3,(H,39,42) CCJJBAOBCOBULM-UHFFFAOYSA-N 50039878 4'-[3-(2-Methyl-cyclopropylmethyl)-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL94176 Type-2 angiotensin II receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039878 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039878&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10100723 103947073 CHEMBL94176 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062815 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1sccc1Br InChI=1S/C31H26BrF3N4O4S2/c1-2-3-12-27-36-39(25-10-6-5-9-23(25)31(33,34)35)30(41)38(27)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)28-24(32)17-18-44-28/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) GUIPGOBVMNVLJL-UHFFFAOYSA-N 50039879 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-bromo-thiophene-2-carbonyl)-amide::CHEMBL321363 Type-2 angiotensin II receptor Rattus norvegicus 43 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039879 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039879&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417431 103947074 CHEMBL321363 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062816 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCCC1 InChI=1S/C33H35F3N4O4S/c1-2-3-17-30-37-40(28-15-9-8-14-27(28)33(34,35)36)32(42)39(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)45(43,44)38-31(41)25-11-5-4-6-12-25/h7-10,13-16,18-21,25H,2-6,11-12,17,22H2,1H3,(H,38,41) KLYVARHCIOHMIV-UHFFFAOYSA-N 50039880 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclohexanecarbonyl-amide::CHEMBL94905 Type-2 angiotensin II receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039880 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039880&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326797 103947075 CHEMBL94905 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062817 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccoc1C InChI=1S/C32H29F3N4O5S/c1-3-4-13-29-36-39(27-11-7-6-10-26(27)32(33,34)35)31(41)38(29)20-22-14-16-23(17-15-22)25-9-5-8-12-28(25)45(42,43)37-30(40)24-18-19-44-21(24)2/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) CJGZUWKIXNNPQK-UHFFFAOYSA-N 50039881 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-methyl-furan-3-carbonyl)-amide::CHEMBL95198 Type-2 angiotensin II receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039881 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039881&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10233073 103947076 CHEMBL95198 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062821 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1-c1ccccc1 InChI=1S/C39H33F3N4O4S/c1-2-3-21-36-43-46(34-19-11-10-18-33(34)39(40,41)42)38(48)45(36)26-27-22-24-29(25-23-27)31-16-9-12-20-35(31)51(49,50)44-37(47)32-17-8-7-15-30(32)28-13-5-4-6-14-28/h4-20,22-25H,2-3,21,26H2,1H3,(H,44,47) LDVDMGJMFCRHCA-UHFFFAOYSA-N 50039884 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (biphenyl-2-carbonyl)-amide::CHEMBL97465 Type-2 angiotensin II receptor Rattus norvegicus 330 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039884 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039884&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10010027 103947079 CHEMBL97465 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062825 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(OC)c(OC)c(OC)c1 InChI=1S/C36H35F3N4O7S/c1-5-6-15-32-40-43(28-13-9-8-12-27(28)36(37,38)39)35(45)42(32)22-23-16-18-24(19-17-23)26-11-7-10-14-31(26)51(46,47)41-34(44)25-20-29(48-2)33(50-4)30(21-25)49-3/h7-14,16-21H,5-6,15,22H2,1-4H3,(H,41,44) KOOAAMQSLAQART-UHFFFAOYSA-N 50039893 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 3,4,5-trimethoxy-benzoylamide::CHEMBL97500 Type-2 angiotensin II receptor Rattus norvegicus 6500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039893 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039893&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10259334 103947088 CHEMBL97500 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062830 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1SCCS1 InChI=1S/C30H29F3N4O4S3/c1-2-3-12-26-34-37(24-10-6-5-9-23(24)30(31,32)33)29(39)36(26)19-20-13-15-21(16-14-20)22-8-4-7-11-25(22)44(40,41)35-27(38)28-42-17-18-43-28/h4-11,13-16,28H,2-3,12,17-19H2,1H3,(H,35,38) HUJNWEJMPLYWRR-UHFFFAOYSA-N 50039894 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid ([1,3]dithiolane-2-carbonyl)-amide::CHEMBL97394 Type-2 angiotensin II receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039894 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039894&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10032342 103947089 CHEMBL97394 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062833 FC(F)(F)CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl InChI=1S/C33H25ClF6N4O4S/c34-26-11-4-1-9-24(26)30(45)42-49(47,48)28-13-6-2-8-23(28)22-17-15-21(16-18-22)20-43-29(14-7-19-32(35,36)37)41-44(31(43)46)27-12-5-3-10-25(27)33(38,39)40/h1-6,8-13,15-18H,7,14,19-20H2,(H,42,45) CBIPYYSLZMYMPZ-UHFFFAOYSA-N 50039858 4'-[5-Oxo-3-(4,4,4-trifluoro-butyl)-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-chloro-benzoylamide::CHEMBL320222 Type-2 angiotensin II receptor Rattus norvegicus 910 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039858 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039858&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372718 103947053 CHEMBL320222 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062837 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1oc(C)cc1C InChI=1S/C33H31F3N4O5S/c1-4-5-14-29-37-40(27-12-8-7-11-26(27)33(34,35)36)32(42)39(29)20-23-15-17-24(18-16-23)25-10-6-9-13-28(25)46(43,44)38-31(41)30-21(2)19-22(3)45-30/h6-13,15-19H,4-5,14,20H2,1-3H3,(H,38,41) AOOWLKVDPNXOHY-UHFFFAOYSA-N 50039899 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3,5-dimethyl-furan-2-carbonyl)-amide::CHEMBL329693 Type-2 angiotensin II receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039899 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039899&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326942 103947094 CHEMBL329693 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062838 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl InChI=1S/C33H28ClF3N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42) FNGNUUQIAIQKKJ-UHFFFAOYSA-N 50035445 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-chloro-benzoylamide::CHEMBL316300 Type-2 angiotensin II receptor Rattus norvegicus 36 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035445 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035445&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809961 103943464 CHEMBL316300 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062839 CCCCc1nc(c(n1Cc2ccc(cc2)c3ccccc3c4[nH]nnn4)C(=O)O)Cl InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28) ZEUXAIYYDDCIRX-UHFFFAOYSA-N 50006909 2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::E 3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::EXP3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL907::Carboxylic Acid Metabolite (E-3174) Type-2 angiotensin II receptor Rattus norvegicus >50000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006909&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search A1ATL 9BR7 108185 103920212 CHEMBL907 C15554 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062845 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NC(C)(C)C InChI=1S/C31H34F3N5O4S/c1-5-6-15-27-36-39(25-13-9-8-12-24(25)31(32,33)34)29(41)38(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)44(42,43)37-28(40)35-30(2,3)4/h7-14,16-19H,5-6,15,20H2,1-4H3,(H2,35,37,40) WZKRVEFOLSRJOQ-UHFFFAOYSA-N 50039890 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-t-butylaminocarbonyl)benzenesulfonamide::CHEMBL98140 Type-2 angiotensin II receptor Rattus norvegicus 130 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039890 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039890&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054753 103947085 CHEMBL98140 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062848 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1 InChI=1S/C30H29F3N4O4S/c1-2-3-12-27-34-37(25-10-6-5-9-24(25)30(31,32)33)29(39)36(27)19-20-13-15-21(16-14-20)23-8-4-7-11-26(23)42(40,41)35-28(38)22-17-18-22/h4-11,13-16,22H,2-3,12,17-19H2,1H3,(H,35,38) JTGPQJDOJHLOHY-UHFFFAOYSA-N 50039901 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclopropanecarbonyl-amide::CHEMBL98126 Type-2 angiotensin II receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039901 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039901&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10438523 103947096 CHEMBL98126 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062852 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(N)(=O)=O InChI=1S/C25H25ClN4O3S/c1-2-3-12-24-28-30(22-10-6-5-9-21(22)26)25(31)29(24)17-18-13-15-19(16-14-18)20-8-4-7-11-23(20)34(27,32)33/h4-11,13-16H,2-3,12,17H2,1H3,(H2,27,32,33) SWBXYUQNJFSFPV-UHFFFAOYSA-N 50039908 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid amide::CHEMBL97783 Type-2 angiotensin II receptor Rattus norvegicus 24000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039908 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039908&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10028815 103947103 CHEMBL97783 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062856 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CC(C)(C)C InChI=1S/C32H35F3N4O4S/c1-5-6-15-28-36-39(26-13-9-8-12-25(26)32(33,34)35)30(41)38(28)21-22-16-18-23(19-17-22)24-11-7-10-14-27(24)44(42,43)37-29(40)20-31(2,3)4/h7-14,16-19H,5-6,15,20-21H2,1-4H3,(H,37,40) RZHQBDADSKJDGW-UHFFFAOYSA-N 50039906 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3,3-dimethyl-butyryl)-amide::CHEMBL432822 Type-2 angiotensin II receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039906 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039906&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10484119 103947101 CHEMBL432822 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062859 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccc(c1)C(F)(F)F InChI=1S/C34H28F6N4O4S/c1-2-3-15-30-41-44(28-13-6-5-12-27(28)34(38,39)40)32(46)43(30)21-22-16-18-23(19-17-22)26-11-4-7-14-29(26)49(47,48)42-31(45)24-9-8-10-25(20-24)33(35,36)37/h4-14,16-20H,2-3,15,21H2,1H3,(H,42,45) GFFCZDIKQXMLDH-UHFFFAOYSA-N 50039912 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 3-trifluoromethyl-benzoylamide::CHEMBL317061 Type-2 angiotensin II receptor Rattus norvegicus 580 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039912 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039912&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078452 103947107 CHEMBL317061 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062860 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1oc2ccccc2c1C InChI=1S/C36H31F3N4O5S/c1-3-4-17-32-40-43(29-14-8-7-13-28(29)36(37,38)39)35(45)42(32)22-24-18-20-25(21-19-24)27-12-6-10-16-31(27)49(46,47)41-34(44)33-23(2)26-11-5-9-15-30(26)48-33/h5-16,18-21H,3-4,17,22H2,1-2H3,(H,41,44) OLBYJPCOVQMYSH-UHFFFAOYSA-N 50039877 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methyl-benzofuran-2-carbonyl)-amide::CHEMBL327988 Type-2 angiotensin II receptor Rattus norvegicus 130 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039877 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039877&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349659 103947072 CHEMBL327988 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062861 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(cc1)C(F)(F)F InChI=1S/C34H28F6N4O4S/c1-2-3-12-30-41-44(28-10-6-5-9-27(28)34(38,39)40)32(46)43(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)49(47,48)42-31(45)24-17-19-25(20-18-24)33(35,36)37/h4-11,13-20H,2-3,12,21H2,1H3,(H,42,45) XGKFJRTZCJHJJY-UHFFFAOYSA-N 50039920 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-trifluoromethyl-benzoylamide::CHEMBL328176 Type-2 angiotensin II receptor Rattus norvegicus 1400 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039920 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039920&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349791 103947115 CHEMBL328176 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062862 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(F)(F)F InChI=1S/C27H24ClF3N4O4S/c1-2-3-12-24-32-35(22-10-6-5-9-21(22)28)26(37)34(24)17-18-13-15-19(16-14-18)20-8-4-7-11-23(20)40(38,39)33-25(36)27(29,30)31/h4-11,13-16H,2-3,12,17H2,1H3,(H,33,36) ACIJKSZKWJVCPE-UHFFFAOYSA-N 50039891 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2,2-trifluoro-acetyl)-amide::CHEMBL94582 Type-2 angiotensin II receptor Rattus norvegicus 450 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039891 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039891&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054188 103947086 CHEMBL94582 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062863 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C InChI=1S/C31H33F3N4O5S/c1-5-6-15-27-35-38(25-13-9-8-12-24(25)31(32,33)34)29(40)37(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)44(41,42)36-28(39)43-30(2,3)4/h7-14,16-19H,5-6,15,20H2,1-4H3,(H,36,39) IVFMKMCSJZZCKV-UHFFFAOYSA-N 50035451 4'-[3-Butyl-5-oxo-1-(2-trifluoromet hyl-phenyl)-15-dihydro-[124]tria zol-4-ylmethyl]-biphenyl-2-sulfonic acid t-butyloxycarbonylamide (L-162234)::L-162234::5-n-Butyl-4-[[2'-[N-(tert-butoxycarbonyl)sulfamoyl]biphenyl-4yl]methyl]-2-[2-trifluoromethyl-phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one::4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-tert-butoxycarbonyl)amide::4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid amide-N-carbonyoxylterbutyl::2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-t-butoxycarbonyl)benzenesulfonamide::CHEMBL292150 Type-2 angiotensin II receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035451 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035451&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9830680 103943470 CHEMBL292150 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062864 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1NS(=O)(=O)C(F)(F)F InChI=1S/C27H24F6N4O3S/c1-2-3-12-24-34-37(23-11-7-5-9-21(23)26(28,29)30)25(38)36(24)17-18-13-15-19(16-14-18)20-8-4-6-10-22(20)35-41(39,40)27(31,32)33/h4-11,13-16,35H,2-3,12,17H2,1H3 OWGRILLFWDIDSB-UHFFFAOYSA-N 50039892 N-{4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-yl}-C,C,C-trifluoro-methanesulfonamide::CHEMBL330007 Type-2 angiotensin II receptor Rattus norvegicus 5500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039892 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039892&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10100074 103947087 CHEMBL330007 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062866 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(C)(C)C InChI=1S/C29H33ClN4O3S/c1-5-6-15-27-31-34(25-13-9-8-12-24(25)30)28(35)33(27)20-21-16-18-22(19-17-21)23-11-7-10-14-26(23)38(36,37)32-29(2,3)4/h7-14,16-19,32H,5-6,15,20H2,1-4H3 YRHWEGNWYOPJSQ-UHFFFAOYSA-N 50039907 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid tert-butylamide::CHEMBL97273 Type-2 angiotensin II receptor Rattus norvegicus 11000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039907 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039907&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 11757357 103947102 CHEMBL97273 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062867 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCOC1 InChI=1S/C31H31F3N4O5S/c1-2-3-12-28-35-38(26-10-6-5-9-25(26)31(32,33)34)30(40)37(28)19-21-13-15-22(16-14-21)24-8-4-7-11-27(24)44(41,42)36-29(39)23-17-18-43-20-23/h4-11,13-16,23H,2-3,12,17-20H2,1H3,(H,36,39) HSXNIXKCCIQHQC-UHFFFAOYSA-N 50039918 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (tetrahydro-furan-3-carbonyl)-amide::CHEMBL97812 Type-2 angiotensin II receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039918 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039918&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349029 103947113 CHEMBL97812 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062868 CCCCc1nn(-c2c(Cl)cccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 |(.21,-2.67,;1.31,-3.74,;2.78,-3.34,;3.9,-4.42,;5.37,-4,;5.91,-2.57,;7.45,-2.62,;8.41,-1.41,;7.84,.02,;6.3,.23,;8.78,1.21,;10.31,1,;10.88,-.44,;9.92,-1.64,;10.48,-3.09,;7.87,-4.11,;9.31,-4.65,;6.59,-4.95,;6.52,-6.49,;7.82,-7.33,;7.73,-8.87,;9.04,-9.69,;10.41,-8.98,;10.46,-7.43,;9.17,-6.61,;11.7,-9.8,;11.63,-11.35,;12.93,-12.16,;14.29,-11.46,;14.36,-9.9,;13.05,-9.08,;13.11,-7.54,;14.65,-7.54,;11.57,-7.54,;13.1,-6,;14.43,-5.23,;14.42,-3.69,;15.77,-5.98,;15.78,-7.52,;17.11,-8.28,;18.44,-7.5,;18.42,-5.96,;17.09,-5.2,)| InChI=1S/C32H28Cl2N4O4S/c1-2-3-16-29-35-38(30-26(33)13-9-14-27(30)34)32(40)37(29)21-22-17-19-23(20-18-22)25-12-7-8-15-28(25)43(41,42)36-31(39)24-10-5-4-6-11-24/h4-15,17-20H,2-3,16,21H2,1H3,(H,36,39) ZEJZITXXPIVLML-UHFFFAOYSA-N 50039919 4'-[3-Butyl-1-(2,6-dichloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL18606 Type-2 angiotensin II receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039919 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039919&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 11764669 103947114 CHEMBL18606 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062869 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C33H29F3N4O4S/c1-2-3-17-30-37-40(28-15-9-8-14-27(28)33(34,35)36)32(42)39(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)45(43,44)38-31(41)25-11-5-4-6-12-25/h4-16,18-21H,2-3,17,22H2,1H3,(H,38,41) JVOGASLNIGJLLS-UHFFFAOYSA-N 50030727 L-159,913::CHEMBL97539::CHEMBL279629::4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::L-159913 Type-2 angiotensin II receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030727 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030727&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9939191 103939575 CHEMBL279629CHEMBL97539 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062870 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)o1 InChI=1S/C31H26BrF3N4O5S/c1-2-3-12-28-36-39(24-10-6-5-9-23(24)31(33,34)35)30(41)38(28)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)25-17-18-27(32)44-25/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) WNYLIIWRLGEPDO-UHFFFAOYSA-N 50039913 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-bromo-furan-2-carbonyl)-amide::CHEMBL327191 Type-2 angiotensin II receptor Rattus norvegicus 170 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039913 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039913&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10394995 103947108 CHEMBL327191 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062872 CCCCCCCC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nn(-c3ccccc3C(F)(F)F)c2=O)cc1 InChI=1S/C34H39F3N4O4S/c1-3-5-7-8-9-19-32(42)39-46(44,45)30-17-13-10-14-27(30)26-22-20-25(21-23-26)24-40-31(18-6-4-2)38-41(33(40)43)29-16-12-11-15-28(29)34(35,36)37/h10-17,20-23H,3-9,18-19,24H2,1-2H3,(H,39,42) FEZRQMGQHANOOE-UHFFFAOYSA-N 50039915 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid octanoyl-amide::CHEMBL274712 Type-2 angiotensin II receptor Rattus norvegicus 450 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039915 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039915&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055096 103947110 CHEMBL274712 C16236 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062875 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccco1 InChI=1S/C31H27F3N4O5S/c1-2-3-14-28-35-38(25-11-6-5-10-24(25)31(32,33)34)30(40)37(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)44(41,42)36-29(39)26-12-8-19-43-26/h4-13,15-19H,2-3,14,20H2,1H3,(H,36,39) OQYLAHYLTMNIEX-UHFFFAOYSA-N 50039922 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (furan-2-carbonyl)-amide::CHEMBL95579 Type-2 angiotensin II receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039922 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039922&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416475 103947117 CHEMBL95579 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062876 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1sccc1Cl InChI=1S/C31H26ClF3N4O4S2/c1-2-3-12-27-36-39(25-10-6-5-9-23(25)31(33,34)35)30(41)38(27)19-20-13-15-21(16-14-20)22-8-4-7-11-26(22)45(42,43)37-29(40)28-24(32)17-18-44-28/h4-11,13-18H,2-3,12,19H2,1H3,(H,37,40) KJDIKXLNGXMGRU-UHFFFAOYSA-N 50039885 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-chloro-thiophene-2-carbonyl)-amide::CHEMBL97446 Type-2 angiotensin II receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039885 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039885&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9875044 103947080 CHEMBL97446 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062877 CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1 InChI=1S/C29H27F3N4O4S/c1-2-7-26-33-36(24-10-5-4-9-23(24)29(30,31)32)28(38)35(26)18-19-12-14-20(15-13-19)22-8-3-6-11-25(22)41(39,40)34-27(37)21-16-17-21/h3-6,8-15,21H,2,7,16-18H2,1H3,(H,34,37) OILHOKMGGIVWPB-UHFFFAOYSA-N 50039898 4'-[5-Oxo-3-propyl-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclopropanecarbonyl-amide::CHEMBL319955 Type-2 angiotensin II receptor Rattus norvegicus 410 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039898 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039898&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10099830 103947093 CHEMBL319955 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062881 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1(C)CC1 InChI=1S/C31H31F3N4O4S/c1-3-4-13-27-35-38(25-11-7-6-10-24(25)31(32,33)34)29(40)37(27)20-21-14-16-22(17-15-21)23-9-5-8-12-26(23)43(41,42)36-28(39)30(2)18-19-30/h5-12,14-17H,3-4,13,18-20H2,1-2H3,(H,36,39) QNLLWVNFFXLKJP-UHFFFAOYSA-N 50039875 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (1-methyl-cyclopropanecarbonyl)-amide::CHEMBL327563 Type-2 angiotensin II receptor Rattus norvegicus 76 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039875 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039875&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10483888 103947070 CHEMBL327563 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062886 CCCCc1nn(C(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C29H32N4O4S/c1-4-5-15-27-30-33(21(2)3)29(35)32(27)20-22-16-18-23(19-17-22)25-13-9-10-14-26(25)38(36,37)31-28(34)24-11-7-6-8-12-24/h6-14,16-19,21H,4-5,15,20H2,1-3H3,(H,31,34) WVYPOJYKXIHIOB-UHFFFAOYSA-N 50039905 4'-(3-Butyl-1-isopropyl-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl)-biphenyl-2-sulfonic acid benzoylamide::CHEMBL318891 Type-2 angiotensin II receptor Rattus norvegicus 4600 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039905 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039905&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10075750 103947100 CHEMBL318891 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062890 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1C(F)(F)F InChI=1S/C34H28F6N4O4S/c1-2-3-16-30-41-44(28-14-8-7-13-27(28)34(38,39)40)32(46)43(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)49(47,48)42-31(45)25-11-4-6-12-26(25)33(35,36)37/h4-15,17-20H,2-3,16,21H2,1H3,(H,42,45) GOORPKDJWMFHLB-UHFFFAOYSA-N 50039926 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-trifluoromethyl-benzoylamide::CHEMBL407919 Type-2 angiotensin II receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039926 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039926&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055534 103947121 CHEMBL407919 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062891 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(C)C InChI=1S/C30H31F3N4O4S/c1-4-5-14-27-34-37(25-12-8-7-11-24(25)30(31,32)33)29(39)36(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)42(40,41)35-28(38)20(2)3/h6-13,15-18,20H,4-5,14,19H2,1-3H3,(H,35,38) GWEIZWXOSOXGRV-UHFFFAOYSA-N 50039896 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid isobutyryl-amide::CHEMBL94910 Type-2 angiotensin II receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039896 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039896&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10483726 103947091 CHEMBL94910 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062892 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccc(Cl)c1 InChI=1S/C33H28ClF3N4O4S/c1-2-3-15-30-38-41(28-13-6-5-12-27(28)33(35,36)37)32(43)40(30)21-22-16-18-23(19-17-22)26-11-4-7-14-29(26)46(44,45)39-31(42)24-9-8-10-25(34)20-24/h4-14,16-20H,2-3,15,21H2,1H3,(H,39,42) OSGLCHDZVVFCBG-UHFFFAOYSA-N 50039868 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 3-chloro-benzoylamide::CHEMBL97615 Type-2 angiotensin II receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039868 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039868&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349506 103947063 CHEMBL97615 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062893 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NS(=O)(=O)c1ccccc1 InChI=1S/C32H29F3N4O5S2/c1-2-3-17-30-36-39(28-15-9-8-14-27(28)32(33,34)35)31(40)38(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)46(43,44)37-45(41,42)25-11-5-4-6-12-25/h4-16,18-21,37H,2-3,17,22H2,1H3 FISKGPNVOMOSRW-UHFFFAOYSA-N 50039895 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-phenylsulphonyl)benzenesulfonamide::CHEMBL97332 Type-2 angiotensin II receptor Rattus norvegicus 2400 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039895 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039895&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349512 103947090 CHEMBL97332 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062895 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C32H29ClN4O4S/c1-2-3-17-30-34-37(28-15-9-8-14-27(28)33)32(39)36(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)42(40,41)35-31(38)25-11-5-4-6-12-25/h4-16,18-21H,2-3,17,22H2,1H3,(H,35,38) LEOPIANEXZTGSQ-UHFFFAOYSA-N 50039888 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL275160 Type-2 angiotensin II receptor Rattus norvegicus 590 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039888 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039888&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054324 103947083 CHEMBL275160 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062896 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NS(=O)(=O)C(C)C InChI=1S/C29H31F3N4O5S2/c1-4-5-14-27-33-36(25-12-8-7-11-24(25)29(30,31)32)28(37)35(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)43(40,41)34-42(38,39)20(2)3/h6-13,15-18,20,34H,4-5,14,19H2,1-3H3 NGRWJNOGBNJYQQ-UHFFFAOYSA-N 50039929 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-isopropylaminosulphonyl)benzenesulfonamide::CHEMBL316706 Type-2 angiotensin II receptor Rattus norvegicus 3600 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039929 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039929&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10009273 103947124 CHEMBL316706 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062898 CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nn(-c3ccccc3C(F)(F)F)c2=O)cc1 InChI=1S/C31H33F3N4O5S/c1-3-5-15-28-35-38(26-13-9-8-12-25(26)31(32,33)34)30(40)37(28)21-22-16-18-23(19-17-22)24-11-7-10-14-27(24)44(41,42)36-29(39)43-20-6-4-2/h7-14,16-19H,3-6,15,20-21H2,1-2H3,(H,36,39) BCSNTIJHQVSLMI-UHFFFAOYSA-N 50039927 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-butoxycarbonyl)benzenesulfonamide::CHEMBL316482 Type-2 angiotensin II receptor Rattus norvegicus 190 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039927 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039927&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9960852 103947122 CHEMBL316482 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062899 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCC(C)C InChI=1S/C31H33F3N4O5S/c1-4-5-14-28-35-38(26-12-8-7-11-25(26)31(32,33)34)30(40)37(28)19-22-15-17-23(18-16-22)24-10-6-9-13-27(24)44(41,42)36-29(39)43-20-21(2)3/h6-13,15-18,21H,4-5,14,19-20H2,1-3H3,(H,36,39) LETRMRLPBCPJMA-UHFFFAOYSA-N 50039864 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-isobutoxycarbonyl)benzenesulfonamide::CHEMBL97068 Type-2 angiotensin II receptor Rattus norvegicus 170 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039864 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039864&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077743 103947059 CHEMBL97068 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062901 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(F)(F)F InChI=1S/C28H24F6N4O4S/c1-2-3-12-24-35-38(22-10-6-5-9-21(22)27(29,30)31)26(40)37(24)17-18-13-15-19(16-14-18)20-8-4-7-11-23(20)43(41,42)36-25(39)28(32,33)34/h4-11,13-16H,2-3,12,17H2,1H3,(H,36,39) MIKVDFTVMKFWBK-UHFFFAOYSA-N 50039928 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2,2-trifluoro-acetyl)-amide::CHEMBL329759 Type-2 angiotensin II receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039928 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039928&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416501 103947123 CHEMBL329759 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062902 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(Br)sc1Br InChI=1S/C31H25Br2F3N4O4S2/c1-2-3-12-27-37-40(24-10-6-5-9-23(24)31(34,35)36)30(42)39(27)18-19-13-15-20(16-14-19)21-8-4-7-11-25(21)46(43,44)38-29(41)22-17-26(32)45-28(22)33/h4-11,13-17H,2-3,12,18H2,1H3,(H,38,41) CQHRAIJPPWOOSU-UHFFFAOYSA-N 50039852 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,5-dibromo-thiophene-3-carbonyl)-amide::CHEMBL98453 Type-2 angiotensin II receptor Rattus norvegicus 84 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039852 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039852&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10350378 103947047 CHEMBL98453 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062903 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1occ(Cl)c1Cl InChI=1S/C31H25Cl2F3N4O5S/c1-2-3-12-26-37-40(24-10-6-5-9-22(24)31(34,35)36)30(42)39(26)17-19-13-15-20(16-14-19)21-8-4-7-11-25(21)46(43,44)38-29(41)28-27(33)23(32)18-45-28/h4-11,13-16,18H,2-3,12,17H2,1H3,(H,38,41) DOUAJXVODABWRT-UHFFFAOYSA-N 50039930 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3,4-dichloro-furan-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL329290 Type-2 angiotensin II receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039930 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039930&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078397 103947125 CHEMBL329290 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062905 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccs1 InChI=1S/C31H27F3N4O4S2/c1-2-3-14-28-35-38(25-11-6-5-10-24(25)31(32,33)34)30(40)37(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)44(41,42)36-29(39)26-12-8-19-43-26/h4-13,15-19H,2-3,14,20H2,1H3,(H,36,39) ONISZXSDXWTXDP-UHFFFAOYSA-N 50039916 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (thiophene-2-carbonyl)-amide::CHEMBL314812 Type-2 angiotensin II receptor Rattus norvegicus 540 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039916 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039916&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9830839 103947111 CHEMBL314812 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062906 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC#N InChI=1S/C27H24F3N5O3S/c1-2-3-12-25-33-35(23-10-6-5-9-22(23)27(28,29)30)26(36)34(25)17-19-13-15-20(16-14-19)21-8-4-7-11-24(21)39(37,38)32-18-31/h4-11,13-16,32H,2-3,12,17H2,1H3 JGMCHTAMZJGMIP-UHFFFAOYSA-N 50039910 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-cyano)benzenesulfonamide::CHEMBL94407 Type-2 angiotensin II receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039910 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039910&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10460346 103947105 CHEMBL94407 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062907 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1sccc1C InChI=1S/C32H29F3N4O4S2/c1-3-4-13-28-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(28)20-22-14-16-23(17-15-22)24-9-5-8-12-27(24)45(42,43)37-30(40)29-21(2)18-19-44-29/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) MMDNKTXNUZFVKD-UHFFFAOYSA-N 50039902 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methyl-thiophene-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL97688 Type-2 angiotensin II receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039902 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039902&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9961192 103947097 CHEMBL97688 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062908 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(C)oc1C(F)(F)F InChI=1S/C33H28F6N4O5S/c1-3-4-13-28-40-43(26-11-7-6-10-25(26)32(34,35)36)31(45)42(28)19-21-14-16-22(17-15-21)23-9-5-8-12-27(23)49(46,47)41-30(44)24-18-20(2)48-29(24)33(37,38)39/h5-12,14-18H,3-4,13,19H2,1-2H3,(H,41,44) BNFFMFZFKZQWDG-UHFFFAOYSA-N 50039882 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-methyl-2-trifluoromethyl-furan-3-carbonyl)-amide::CHEMBL97075 Type-2 angiotensin II receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039882 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039882&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417351 103947077 CHEMBL97075 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062909 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCOC InChI=1S/C30H31F3N4O5S/c1-3-4-13-27-34-37(25-11-7-6-10-24(25)30(31,32)33)29(39)36(27)20-21-14-16-22(17-15-21)23-9-5-8-12-26(23)43(40,41)35-28(38)18-19-42-2/h5-12,14-17H,3-4,13,18-20H2,1-2H3,(H,35,38) PPWHZKADGPDDCI-UHFFFAOYSA-N 50039931 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methoxy-propionyl)-amide::CHEMBL93956 Type-2 angiotensin II receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039931 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039931&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077555 103947126 CHEMBL93956 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062911 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1C InChI=1S/C31H31F3N4O4S/c1-3-4-13-28-35-38(26-11-7-6-10-25(26)31(32,33)34)30(40)37(28)19-21-14-16-22(17-15-21)23-9-5-8-12-27(23)43(41,42)36-29(39)24-18-20(24)2/h5-12,14-17,20,24H,3-4,13,18-19H2,1-2H3,(H,36,39) KXYFGMIPNUPRJC-UHFFFAOYSA-N 50039867 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-methyl-cyclopropanecarbonyl)-amide::CHEMBL316655 Type-2 angiotensin II receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039867 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039867&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10438745 103947062 CHEMBL316655 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062917 CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) JGABCUJSSAEYFF-UHFFFAOYSA-N 50009714 CHEMBL191::{2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-3H-imidazol-4-yl}-methanol(DuP 753) Type-2 angiotensin II receptor Rattus norvegicus 74000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009714 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009714&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 44330456 103922696 CHEMBL191 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062919 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CC1(F)F InChI=1S/C30H27F5N4O4S/c1-2-3-12-26-36-39(24-10-6-5-9-22(24)30(33,34)35)28(41)38(26)18-19-13-15-20(16-14-19)21-8-4-7-11-25(21)44(42,43)37-27(40)23-17-29(23,31)32/h4-11,13-16,23H,2-3,12,17-18H2,1H3,(H,37,40) ULBQOFYLQNBFKK-UHFFFAOYSA-N 50039909 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2-difluoro-cyclopropanecarbonyl)-amide::CHEMBL321367 Type-2 angiotensin II receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039909&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9874086 103947104 CHEMBL321367 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062920 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc2ccccc2o1 InChI=1S/C35H29F3N4O5S/c1-2-3-16-32-39-42(28-13-7-6-12-27(28)35(36,37)38)34(44)41(32)22-23-17-19-24(20-18-23)26-11-5-9-15-31(26)48(45,46)40-33(43)30-21-25-10-4-8-14-29(25)47-30/h4-15,17-21H,2-3,16,22H2,1H3,(H,40,43) SGYXRZTXQJMDGN-UHFFFAOYSA-N 50039887 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (benzofuran-2-carbonyl)-amide; compound with ethoxy-ethane::CHEMBL98068 Type-2 angiotensin II receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039887 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039887&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10258974 103947082 CHEMBL98068 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062921 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCCC(O)=O InChI=1S/C31H31F3N4O6S/c1-2-3-13-27-35-38(25-11-6-5-10-24(25)31(32,33)34)30(42)37(27)20-21-16-18-22(19-17-21)23-9-4-7-12-26(23)45(43,44)36-28(39)14-8-15-29(40)41/h4-7,9-12,16-19H,2-3,8,13-15,20H2,1H3,(H,36,39)(H,40,41) KDMXTHPIIMPHJG-UHFFFAOYSA-N 50039936 5-{4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonylamino}-5-oxo-pentanoic acid::CHEMBL94355 Type-2 angiotensin II receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039936 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039936&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439172 103947131 CHEMBL94355 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062923 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(C)=O InChI=1S/C27H27ClN4O4S/c1-3-4-13-26-29-32(24-11-7-6-10-23(24)28)27(34)31(26)18-20-14-16-21(17-15-20)22-9-5-8-12-25(22)37(35,36)30-19(2)33/h5-12,14-17H,3-4,13,18H2,1-2H3,(H,30,33) PXKSZDRAQKHPND-UHFFFAOYSA-N 50039933 4'-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid acetyl-amide::CHEMBL318042 Type-2 angiotensin II receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039933 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039933&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10437270 103947128 CHEMBL318042 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062928 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H24F3N7O/c1-2-3-12-24-33-37(23-11-7-6-10-22(23)27(28,29)30)26(38)36(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-31-34-35-32-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,31,32,34,35) DWXCNNUZEBMCMR-UHFFFAOYSA-N 50035431 5-Butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2-trifluoromethyl-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2-trifluoromethyl-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL19018 Type-2 angiotensin II receptor Rattus norvegicus 23000 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035431&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956757 103943450 CHEMBL19018 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062931 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(C)oc1C InChI=1S/C33H31F3N4O5S/c1-4-5-14-30-37-40(28-12-8-7-11-27(28)33(34,35)36)32(42)39(30)20-23-15-17-24(18-16-23)25-10-6-9-13-29(25)46(43,44)38-31(41)26-19-21(2)45-22(26)3/h6-13,15-19H,4-5,14,20H2,1-3H3,(H,38,41) RDCONBROTQSADP-UHFFFAOYSA-N 50039900 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,5-dimethyl-furan-3-carbonyl)-amide::CHEMBL329255 Type-2 angiotensin II receptor Rattus norvegicus 310 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039900 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039900&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439253 103947095 CHEMBL329255 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062933 FC(F)(F)CCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C33H26F6N4O4S/c34-32(35,36)20-8-15-29-40-43(27-13-6-5-12-26(27)33(37,38)39)31(45)42(29)21-22-16-18-23(19-17-22)25-11-4-7-14-28(25)48(46,47)41-30(44)24-9-2-1-3-10-24/h1-7,9-14,16-19H,8,15,20-21H2,(H,41,44) VSSNYYVTPWFYPM-UHFFFAOYSA-N 50039857 4'-[5-Oxo-3-(4,4,4-trifluoro-butyl)-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL414816 Type-2 angiotensin II receptor Rattus norvegicus >300 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039857 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039857&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439612 103947052 CHEMBL414816 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062935 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccn1C InChI=1S/C32H30F3N5O4S/c1-3-4-15-29-36-40(26-12-7-6-11-25(26)32(33,34)35)31(42)39(29)21-22-16-18-23(19-17-22)24-10-5-8-14-28(24)45(43,44)37-30(41)27-13-9-20-38(27)2/h5-14,16-20H,3-4,15,21H2,1-2H3,(H,37,41) MDWZSHJNBJBDCC-UHFFFAOYSA-N 50039934 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (1-methyl-1H-pyrrole-2-carbonyl)-amide::CHEMBL316297 Type-2 angiotensin II receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039934 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039934&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10233056 103947129 CHEMBL316297 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062939 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(Cl)ccc1Cl InChI=1S/C33H27Cl2F3N4O4S/c1-2-3-12-30-39-42(28-10-6-5-9-26(28)33(36,37)38)32(44)41(30)20-21-13-15-22(16-14-21)24-8-4-7-11-29(24)47(45,46)40-31(43)25-19-23(34)17-18-27(25)35/h4-11,13-19H,2-3,12,20H2,1H3,(H,40,43) KNTYZUJZCJPYJF-UHFFFAOYSA-N 50039883 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2,5-dichloro-benzoylamide::CHEMBL329942 Type-2 angiotensin II receptor Rattus norvegicus 26 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039883 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039883&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10009968 103947078 CHEMBL329942 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062940 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(Cl)cc1 InChI=1S/C33H28ClF3N4O4S/c1-2-3-12-30-38-41(28-10-6-5-9-27(28)33(35,36)37)32(43)40(30)21-22-13-15-23(16-14-22)26-8-4-7-11-29(26)46(44,45)39-31(42)24-17-19-25(34)20-18-24/h4-11,13-20H,2-3,12,21H2,1H3,(H,39,42) IKRYWDCWVGEVKU-UHFFFAOYSA-N 50039942 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-chloro-benzoylamide::CHEMBL95955 Type-2 angiotensin II receptor Rattus norvegicus 520 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039942 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039942&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9986951 103947137 CHEMBL95955 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062941 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCO1 InChI=1S/C31H31F3N4O5S/c1-2-3-14-28-35-38(25-11-6-5-10-24(25)31(32,33)34)30(40)37(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)44(41,42)36-29(39)26-12-8-19-43-26/h4-7,9-11,13,15-18,26H,2-3,8,12,14,19-20H2,1H3,(H,36,39) DUUNHXVRQNGIPB-UHFFFAOYSA-N 50039886 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (tetrahydro-furan-2-carbonyl)-amide::CHEMBL319404 Type-2 angiotensin II receptor Rattus norvegicus 180 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039886 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039886&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10031920 103947081 CHEMBL319404 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062943 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCC1 InChI=1S/C32H33F3N4O4S/c1-2-3-16-29-36-39(27-14-8-7-13-26(27)32(33,34)35)31(41)38(29)21-22-17-19-23(20-18-22)25-12-6-9-15-28(25)44(42,43)37-30(40)24-10-4-5-11-24/h6-9,12-15,17-20,24H,2-5,10-11,16,21H2,1H3,(H,37,40) BPMHTBBVCZRJAP-UHFFFAOYSA-N 50039924 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclopentanecarbonyl-amide::CHEMBL316273 Type-2 angiotensin II receptor Rattus norvegicus 82 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039924 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039924&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10054708 103947119 CHEMBL316273 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062946 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)COCC InChI=1S/C30H31F3N4O5S/c1-3-5-14-27-34-37(25-12-8-7-11-24(25)30(31,32)33)29(39)36(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)43(40,41)35-28(38)20-42-4-2/h6-13,15-18H,3-5,14,19-20H2,1-2H3,(H,35,38) KQJQNVZAJRKQLW-UHFFFAOYSA-N 50039889 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-ethoxy-acetyl)-amide::CHEMBL409058 Type-2 angiotensin II receptor Rattus norvegicus 380 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039889 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039889&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9986299 103947084 CHEMBL409058 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062948 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cc1ccccc1 InChI=1S/C40H35F3N4O4S/c1-2-3-21-37-44-47(35-19-11-10-18-34(35)40(41,42)43)39(49)46(37)27-29-22-24-30(25-23-29)32-16-9-12-20-36(32)52(50,51)45-38(48)33-17-8-7-15-31(33)26-28-13-5-4-6-14-28/h4-20,22-25H,2-3,21,26-27H2,1H3,(H,45,48) DGADYUCYHDLBMN-UHFFFAOYSA-N 50039940 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-benzyl-benzoylamide::CHEMBL97464 Type-2 angiotensin II receptor Rattus norvegicus 190 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039940 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039940&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10010125 103947135 CHEMBL97464 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062949 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1C(C)(C)C1(C)C InChI=1S/C34H37F3N4O4S/c1-6-7-16-28-38-41(26-14-10-9-13-25(26)34(35,36)37)31(43)40(28)21-22-17-19-23(20-18-22)24-12-8-11-15-27(24)46(44,45)39-30(42)29-32(2,3)33(29,4)5/h8-15,17-20,29H,6-7,16,21H2,1-5H3,(H,39,42) QKLZIKJSBBMLRK-UHFFFAOYSA-N 50039945 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,2,3,3-tetramethyl-cyclopropanecarbonyl)-amide::CHEMBL432392 Type-2 angiotensin II receptor Rattus norvegicus 130 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039945 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039945&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10439275 103947140 CHEMBL432392 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062950 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(Cl)sc1Cl InChI=1S/C31H25Cl2F3N4O4S2/c1-2-3-12-27-37-40(24-10-6-5-9-23(24)31(34,35)36)30(42)39(27)18-19-13-15-20(16-14-19)21-8-4-7-11-25(21)46(43,44)38-29(41)22-17-26(32)45-28(22)33/h4-11,13-17H,2-3,12,18H2,1H3,(H,38,41) IXSJGZOXWQGYRR-UHFFFAOYSA-N 50039861 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2,5-dichloro-thiophene-3-carbonyl)-amide; compound with dichloro-methane::CHEMBL97271 Type-2 angiotensin II receptor Rattus norvegicus 87 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039861 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039861&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349845 103947056 CHEMBL97271 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062951 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1c(C)cccc1C InChI=1S/C35H33F3N4O4S/c1-4-5-17-31-39-42(29-15-8-7-14-28(29)35(36,37)38)34(44)41(31)22-25-18-20-26(21-19-25)27-13-6-9-16-30(27)47(45,46)40-33(43)32-23(2)11-10-12-24(32)3/h6-16,18-21H,4-5,17,22H2,1-3H3,(H,40,43) KFZJBZUZBZQWGB-UHFFFAOYSA-N 50039944 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2,6-dimethyl-benzoylamide::CHEMBL327791 Type-2 angiotensin II receptor Rattus norvegicus 190 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039944 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039944&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416957 103947139 CHEMBL327791 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062953 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc2ccccc2s1 InChI=1S/C35H29F3N4O4S2/c1-2-3-16-32-39-42(28-13-7-6-12-27(28)35(36,37)38)34(44)41(32)22-23-17-19-24(20-18-23)26-11-5-9-15-31(26)48(45,46)40-33(43)30-21-25-10-4-8-14-29(25)47-30/h4-15,17-21H,2-3,16,22H2,1H3,(H,40,43) SIEOBZYPHMFGHF-UHFFFAOYSA-N 50039938 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (benzo[b]thiophene-2-carbonyl)-amide; compound with dichloro-methane::CHEMBL411487 Type-2 angiotensin II receptor Rattus norvegicus 430 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039938 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039938&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10032583 103947133 CHEMBL411487 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062955 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ocnc1C InChI=1S/C31H28F3N5O5S/c1-3-4-13-27-36-39(25-11-7-6-10-24(25)31(32,33)34)30(41)38(27)18-21-14-16-22(17-15-21)23-9-5-8-12-26(23)45(42,43)37-29(40)28-20(2)35-19-44-28/h5-12,14-17,19H,3-4,13,18H2,1-2H3,(H,37,40) RMFBHOGJDSQPMB-UHFFFAOYSA-N 50039939 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (4-methyl-oxazole-5-carbonyl)-amide; compound with dichloro-methane::CHEMBL262296 Type-2 angiotensin II receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039939 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039939&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10461785 103947134 CHEMBL262296 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062959 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccc(Cl)c1Cl InChI=1S/C33H27Cl2F3N4O4S/c1-2-3-15-29-39-42(27-13-6-5-11-25(27)33(36,37)38)32(44)41(29)20-21-16-18-22(19-17-21)23-9-4-7-14-28(23)47(45,46)40-31(43)24-10-8-12-26(34)30(24)35/h4-14,16-19H,2-3,15,20H2,1H3,(H,40,43) LQLOVKYYMGPNEF-UHFFFAOYSA-N 50039943 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2,3-dichloro-benzoylamide::CHEMBL319353 Type-2 angiotensin II receptor Rattus norvegicus 780 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039943 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039943&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349801 103947138 CHEMBL319353 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062962 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NC(C)C InChI=1S/C30H32F3N5O4S/c1-4-5-14-27-35-38(25-12-8-7-11-24(25)30(31,32)33)29(40)37(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)43(41,42)36-28(39)34-20(2)3/h6-13,15-18,20H,4-5,14,19H2,1-3H3,(H2,34,36,39) HEHVZBBAYSZOSP-UHFFFAOYSA-N 50039937 2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,5-dihydro-1H-1,2,4-triazol-4-ylmethyl]phenyl}-1-(N-isopropylaminocarbonyl)benzenesulfonamide::CHEMBL330170 Type-2 angiotensin II receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039937 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039937&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10348847 103947132 CHEMBL330170 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062963 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1occc1C InChI=1S/C32H29F3N4O5S/c1-3-4-13-28-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(28)20-22-14-16-23(17-15-22)24-9-5-8-12-27(24)45(42,43)37-30(40)29-21(2)18-19-44-29/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) FAZPIUJZFLKBPJ-UHFFFAOYSA-N 50039921 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3-methyl-furan-2-carbonyl)-amide::CHEMBL328941 Type-2 angiotensin II receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039921 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039921&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9895635 103947116 CHEMBL328941 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062970 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccoc1 InChI=1S/C31H27F3N4O5S/c1-2-3-12-28-35-38(26-10-6-5-9-25(26)31(32,33)34)30(40)37(28)19-21-13-15-22(16-14-21)24-8-4-7-11-27(24)44(41,42)36-29(39)23-17-18-43-20-23/h4-11,13-18,20H,2-3,12,19H2,1H3,(H,36,39) XGHGJYYEMSDPFJ-UHFFFAOYSA-N 50039911 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (furan-3-carbonyl)-amide::CHEMBL97964 Type-2 angiotensin II receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039911 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039911&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10461595 103947106 CHEMBL97964 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062971 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCC1 InChI=1S/C31H31F3N4O4S/c1-2-3-15-28-35-38(26-13-6-5-12-25(26)31(32,33)34)30(40)37(28)20-21-16-18-22(19-17-21)24-11-4-7-14-27(24)43(41,42)36-29(39)23-9-8-10-23/h4-7,11-14,16-19,23H,2-3,8-10,15,20H2,1H3,(H,36,39) RIUAOEISGORHGS-UHFFFAOYSA-N 50039917 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cyclobutanecarbonyl-amide; compound with trichloro-methane::CHEMBL98426 Type-2 angiotensin II receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039917 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039917&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077497 103947112 CHEMBL98426 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062972 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1(C)SCCS1 InChI=1S/C31H31F3N4O4S3/c1-3-4-13-27-35-38(25-11-7-6-10-24(25)31(32,33)34)29(40)37(27)20-21-14-16-22(17-15-21)23-9-5-8-12-26(23)45(41,42)36-28(39)30(2)43-18-19-44-30/h5-12,14-17H,3-4,13,18-20H2,1-2H3,(H,36,39) LIENBRWYZMHTGD-UHFFFAOYSA-N 50039946 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-methyl-[1,3]dithiolane-2-carbonyl)-amide::CHEMBL94145 Type-2 angiotensin II receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039946 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039946&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417102 103947141 CHEMBL94145 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062973 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cccnc1Cl InChI=1S/C32H27ClF3N5O4S/c1-2-3-14-28-38-41(26-12-6-5-11-25(26)32(34,35)36)31(43)40(28)20-21-15-17-22(18-16-21)23-9-4-7-13-27(23)46(44,45)39-30(42)24-10-8-19-37-29(24)33/h4-13,15-19H,2-3,14,20H2,1H3,(H,39,42) DZQVFTZIXNLOIV-UHFFFAOYSA-N 50039935 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (2-chloro-pyridine-3-carbonyl)-amide::CHEMBL317864 Type-2 angiotensin II receptor Rattus norvegicus 520 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039935 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039935&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417031 103947130 CHEMBL317864 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062974 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCCCC1 InChI=1S/C34H37F3N4O4S/c1-2-3-18-31-38-41(29-16-10-9-15-28(29)34(35,36)37)33(43)40(31)23-24-19-21-25(22-20-24)27-14-8-11-17-30(27)46(44,45)39-32(42)26-12-6-4-5-7-13-26/h8-11,14-17,19-22,26H,2-7,12-13,18,23H2,1H3,(H,39,42) FTJIFYIITVETKU-UHFFFAOYSA-N 50039904 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid cycloheptanecarbonyl-amide::CHEMBL329099 Type-2 angiotensin II receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039904 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039904&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326972 103947099 CHEMBL329099 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062975 CCCCc1nn(CC(C)(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 InChI=1S/C31H36N4O4S/c1-5-6-16-28-32-35(22-31(2,3)4)30(37)34(28)21-23-17-19-24(20-18-23)26-14-10-11-15-27(26)40(38,39)33-29(36)25-12-8-7-9-13-25/h7-15,17-20H,5-6,16,21-22H2,1-4H3,(H,33,36) GHBYHMXNLNDBNI-UHFFFAOYSA-N 50039925 CHEMBL429058::4''-[3-Butyl-1-(2,2-dimethyl-propyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide; compound with dichloro-methane::CHEMBL321086 Type-2 angiotensin II receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039925 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039925&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10482937 103947120 CHEMBL321086CHEMBL429058 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062976 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(cc1)C#N InChI=1S/C34H28F3N5O4S/c1-2-3-12-31-39-42(29-10-6-5-9-28(29)34(35,36)37)33(44)41(31)22-24-15-17-25(18-16-24)27-8-4-7-11-30(27)47(45,46)40-32(43)26-19-13-23(21-38)14-20-26/h4-11,13-20H,2-3,12,22H2,1H3,(H,40,43) NREVODYWGRCNEM-UHFFFAOYSA-N 50039897 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 4-cyano-benzoylamide::CHEMBL97557 Type-2 angiotensin II receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039897 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039897&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10349392 103947092 CHEMBL97557 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062979 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1OC InChI=1S/C34H31F3N4O5S/c1-3-4-17-31-38-41(28-14-8-7-13-27(28)34(35,36)37)33(43)40(31)22-23-18-20-24(21-19-23)25-11-6-10-16-30(25)47(44,45)39-32(42)26-12-5-9-15-29(26)46-2/h5-16,18-21H,3-4,17,22H2,1-2H3,(H,39,42) AZFWKIXDPPZMAV-UHFFFAOYSA-N 50039903 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-methoxy-benzoylamide::CHEMBL316904 Type-2 angiotensin II receptor Rattus norvegicus 72 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039903 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039903&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078132 103947098 CHEMBL316904 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062982 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(C)o1 InChI=1S/C32H29F3N4O5S/c1-3-4-13-29-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(29)20-22-15-17-23(18-16-22)24-9-5-8-12-28(24)45(42,43)37-30(40)27-19-14-21(2)44-27/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40) GSICYOFDBGKLHW-UHFFFAOYSA-N 50039923 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (5-methyl-furan-2-carbonyl)-amide::CHEMBL329089 Type-2 angiotensin II receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039923 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039923&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10326775 103947118 CHEMBL329089 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062983 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(c1ccccc1)c1ccccc1 InChI=1S/C40H35F3N4O4S/c1-2-3-22-36-44-47(34-20-12-11-19-33(34)40(41,42)43)39(49)46(36)27-28-23-25-29(26-24-28)32-18-10-13-21-35(32)52(50,51)45-38(48)37(30-14-6-4-7-15-30)31-16-8-5-9-17-31/h4-21,23-26,37H,2-3,22,27H2,1H3,(H,45,48) WFPJYSLLXXXCLR-UHFFFAOYSA-N 50039932 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid diphenylacetyl-amide::CHEMBL317368 Type-2 angiotensin II receptor Rattus norvegicus 320 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039932 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039932&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10372723 103947127 CHEMBL317368 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351 50062986 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1C InChI=1S/C34H31F3N4O4S/c1-3-4-17-31-38-41(29-15-9-8-14-28(29)34(35,36)37)33(43)40(31)22-24-18-20-25(21-19-24)27-13-7-10-16-30(27)46(44,45)39-32(42)26-12-6-5-11-23(26)2/h5-16,18-21H,3-4,17,22H2,1-2H3,(H,39,42) VFMXOJKKIIXTLB-UHFFFAOYSA-N 50039941 4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid 2-methyl-benzoylamide::CHEMBL330165 Type-2 angiotensin II receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00043a020 10.7270/Q2M907QM 8064808 Ashton, WT; Chang, LL; Flanagan, KL; Hutchins, SM; Naylor, EM; Chakravarty, PK; Patchett, AA; Greenlee, WJ; Chen, TB; Faust, KA 9/22/1994 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039941 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000274&target=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039941&enzyme=Type-2+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10258694 103947136 CHEMBL330165 1 MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS Type-2 angiotensin II receptor AGTR2_RAT P35351