BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50062732 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50034330 (3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062733 CCCN1CC[C@@H]2[C@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3 VUKJBNUKLLGULS-UHFFFAOYSA-N 50034351 (3aR,9bS)-6-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25177 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944883 103942552 CHEMBL25177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062734 COc1cccc2[C@H]3CCN(CC4CC4)[C@@H]3CCc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-14-9-10-18(11-12-5-6-12)16(14)8-7-15(13)17/h2-4,12,14,16H,5-11H2,1H3 DSBCJIBAHMOGIR-UHFFFAOYSA-N 50034336 (3aR,9bR)-3-Cyclopropylmethyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24532 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034336 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377779 103942537 CHEMBL24532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062735 CCCN1CC[C@H]2[C@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3 VUKJBNUKLLGULS-UHFFFAOYSA-N 50034326 (3aR,9bR)-6-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280137 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034326 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992098 103942527 CHEMBL280137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062736 C=CCN1CC[C@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H19N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h2-6,14-15H,1,7-11H2 KJAVUVIRTPBAPJ-UHFFFAOYSA-N 50034335 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286006 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034335 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353170 103942536 CHEMBL286006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062737 Oc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50034356 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL25483 D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034356 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466368 103942557 CHEMBL25483 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062738 COc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50034339 (3aR,9bR)-3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic)3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286205 D(2) dopamine receptor Homo sapiens 8.5 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034339 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10354437 103942540 CHEMBL286205 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062739 CCCN1CC[C@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50034349 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL24588 D(2) dopamine receptor Homo sapiens 93 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034349 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353846 103942550 CHEMBL24588 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062740 CCCN1CC[C@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H21N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h3-6,14-15H,2,7-11H2,1H3 ANSBSVSYIULXCZ-UHFFFAOYSA-N 50034316 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24496 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034316 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10443274 103942517 CHEMBL24496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062741 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 5-hydroxytryptamine receptor 1A Homo sapiens 16 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062742 C=CCN1CC[C@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H19N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h2-6,14-15H,1,7-11H2 KJAVUVIRTPBAPJ-UHFFFAOYSA-N 50034335 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286006 5-hydroxytryptamine receptor 1A Homo sapiens 11 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034335 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034335&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10353170 103942536 CHEMBL286006 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062743 COc1cccc2[C@@H]3CCN(CC4CC4)[C@@H]3CCc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-14-9-10-18(11-12-5-6-12)16(14)8-7-15(13)17/h2-4,12,14,16H,5-11H2,1H3 DSBCJIBAHMOGIR-UHFFFAOYSA-N 50034315 (3aR,9bS)-3-Cyclopropylmethyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25691 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034315 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992630 103942516 CHEMBL25691 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062744 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 D(2) dopamine receptor Rattus norvegicus 25.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062745 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50034330 (3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062746 Oc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2 NLAWPJROLJRPAW-UHFFFAOYSA-N 50034321 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL283738 D(2) dopamine receptor Homo sapiens 25 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034321 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353777 103942522 CHEMBL283738 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062747 COc1cccc2[C@H]3CCN(CC4CC4)[C@@H]3CCc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-14-9-10-18(11-12-5-6-12)16(14)8-7-15(13)17/h2-4,12,14,16H,5-11H2,1H3 DSBCJIBAHMOGIR-UHFFFAOYSA-N 50034336 (3aR,9bR)-3-Cyclopropylmethyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24532 5-hydroxytryptamine receptor 1A Homo sapiens 66 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034336 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034336&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10377779 103942537 CHEMBL24532 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062748 CCCN1CC[C@@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H21N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h3-6,14-15H,2,7-11H2,1H3 ANSBSVSYIULXCZ-UHFFFAOYSA-N 50034358 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25690 5-hydroxytryptamine receptor 1A Homo sapiens 37 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034358 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034358&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10420841 103942559 CHEMBL25690 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062749 CCCN1CC[C@H]2[C@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3 VUKJBNUKLLGULS-UHFFFAOYSA-N 50034326 (3aR,9bR)-6-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280137 5-hydroxytryptamine receptor 1A Homo sapiens 66 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034326 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034326&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 9992098 103942527 CHEMBL280137 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062750 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 D(2) dopamine receptor Homo sapiens 18.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062751 COc1cccc2CC[C@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50040166 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL418705 5-hydroxytryptamine receptor 1A Mus musculus 100 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7880&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040166&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266613 103972226 CHEMBL418705 1 MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 8JSP 5-hydroxytryptamine receptor 1A 5HT1A_MOUSE Q64264 Q60956 Q61617 Q8BGS4 50062752 Oc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2 NLAWPJROLJRPAW-UHFFFAOYSA-N 50034360 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL287134 5-hydroxytryptamine receptor 1A Homo sapiens 0.300000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034360 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034360&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 14944884 103942561 CHEMBL287134 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062753 Oc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2 NLAWPJROLJRPAW-UHFFFAOYSA-N 50034321 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL283738 5-hydroxytryptamine receptor 1A Homo sapiens 4.9 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034321 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034321&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10353777 103942522 CHEMBL283738 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062754 Oc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50034356 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL25483 5-hydroxytryptamine receptor 1A Homo sapiens 16 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034356 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034356&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10466368 103942557 CHEMBL25483 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062755 CCCN1CC[C@@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50034363 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL26560 D(2) dopamine receptor Homo sapiens 218 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034363 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466454 103942564 CHEMBL26560 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062756 CCCN1CC[C@@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50034363 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL26560 5-hydroxytryptamine receptor 1A Homo sapiens >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034363 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034363&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10466454 103942564 CHEMBL26560 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062757 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 D(2) dopamine receptor Rattus norvegicus 99 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062758 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 5-hydroxytryptamine receptor 1A Homo sapiens 252 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062759 CCCN1CC[C@@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50034363 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL26560 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034363 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466454 103942564 CHEMBL26560 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062760 Oc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2 NLAWPJROLJRPAW-UHFFFAOYSA-N 50034360 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL287134 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034360 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944884 103942561 CHEMBL287134 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062761 COc1cccc2CC[C@@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50040177 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10270 5-hydroxytryptamine receptor 1A Mus musculus 0.200000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7880&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040177&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266664 103972237 CHEMBL10270 1 MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 8JSP 5-hydroxytryptamine receptor 1A 5HT1A_MOUSE Q64264 Q60956 Q61617 Q8BGS4 50062762 CCCN1CC[C@@H]2[C@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3 VUKJBNUKLLGULS-UHFFFAOYSA-N 50034351 (3aR,9bS)-6-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25177 5-hydroxytryptamine receptor 1A Homo sapiens >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034351&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 14944883 103942552 CHEMBL25177 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062763 CCCN1CC[C@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50034349 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL24588 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034349 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353846 103942550 CHEMBL24588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062764 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 D(2) dopamine receptor Homo sapiens 50 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062765 C=CCN1CC[C@@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H19N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h2-6,14-15H,1,7-11H2 KJAVUVIRTPBAPJ-UHFFFAOYSA-N 50034337 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25418 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034337 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10059274 103942538 CHEMBL25418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062766 Oc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50034356 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL25483 D(2) dopamine receptor Homo sapiens 4.1 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034356 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466368 103942557 CHEMBL25483 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062767 Oc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50034355 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::(3aR,9bS)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL285873 D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014056 103942556 CHEMBL285873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062768 CCCN1CC[C@@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H21N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h3-6,14-15H,2,7-11H2,1H3 ANSBSVSYIULXCZ-UHFFFAOYSA-N 50034358 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25690 D(2) dopamine receptor Rattus norvegicus 548 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034358 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10420841 103942559 CHEMBL25690 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062769 Oc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50034355 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::(3aR,9bS)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL285873 5-hydroxytryptamine receptor 1A Homo sapiens 923 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034355&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10014056 103942556 CHEMBL285873 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062770 COc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50034339 (3aR,9bR)-3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic)3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286205 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034339 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10354437 103942540 CHEMBL286205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062771 COc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50034339 (3aR,9bR)-3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic)3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286205 5-hydroxytryptamine receptor 1A Homo sapiens 4.7 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034339 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034339&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10354437 103942540 CHEMBL286205 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062772 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50034330 (3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 5-hydroxytryptamine receptor 1A Homo sapiens 1.2 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062773 CCCN1CC[C@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H21N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h3-6,14-15H,2,7-11H2,1H3 ANSBSVSYIULXCZ-UHFFFAOYSA-N 50034316 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24496 5-hydroxytryptamine receptor 1A Homo sapiens 44 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034316 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034316&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10443274 103942517 CHEMBL24496 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062774 CCCN1CC[C@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50034349 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL24588 5-hydroxytryptamine receptor 1A Homo sapiens 338 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034349 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034349&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10353846 103942550 CHEMBL24588 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062775 COc1cccc2[C@@H]3CCN(CC4CC4)[C@@H]3CCc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-14-9-10-18(11-12-5-6-12)16(14)8-7-15(13)17/h2-4,12,14,16H,5-11H2,1H3 DSBCJIBAHMOGIR-UHFFFAOYSA-N 50034315 (3aR,9bS)-3-Cyclopropylmethyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25691 5-hydroxytryptamine receptor 1A Homo sapiens >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034315 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034315&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 9992630 103942516 CHEMBL25691 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50062776 Oc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50034355 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::(3aR,9bS)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL285873 D(2) dopamine receptor Homo sapiens 75 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014056 103942556 CHEMBL285873 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50062777 C=CCN1CC[C@@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H19N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h2-6,14-15H,1,7-11H2 KJAVUVIRTPBAPJ-UHFFFAOYSA-N 50034337 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25418 5-hydroxytryptamine receptor 1A Homo sapiens 31 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034337 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034337&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10059274 103942538 CHEMBL25418 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063621 CCCN1[C@H](C)CC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C17H25NO/c1-4-10-18-12(2)11-14-15(18)9-8-13-6-5-7-16(19-3)17(13)14/h5-7,12,14-15H,4,8-11H2,1-3H3 FWQJZNALGBTYNB-UHFFFAOYSA-N 50040158 9-Methoxy-2-methyl-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10561 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040158 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266668 103972218 CHEMBL10561 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063625 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 cid_1220::CHEMBL56::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL505765::DPAT::8-OH-DPAT,(-)::8-OH-DPAT,(+)::8-OH-DPAT::8-hydroxy-N,N-dipropylaminotetralin::8-Hydroxy-2-(di-n-propylamino)tetralin::CHEMBL1788118::[3H]-8-OH-DPAT::US10562853, Compound 8-OH-DPAT 5-hydroxytryptamine receptor 1A Homo sapiens 1.6 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 CHEMBL1788118CHEMBL505765CHEMBL56 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063626 CCCN1CCC2[C@@H]1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3 UVOXCNCVSFLEPX-UHFFFAOYSA-N 50040161 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL276185 5-hydroxytryptamine receptor 1A Homo sapiens 3 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040161 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040161&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10014136 103972221 CHEMBL276185 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063634 Oc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040165 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10408 5-hydroxytryptamine receptor 1A Homo sapiens 54 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040165 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040165&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266677 103972225 CHEMBL10408 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063635 CCCN1[C@H](C)CC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C17H25NO/c1-4-10-18-12(2)11-14-15(18)9-8-13-6-5-7-16(19-3)17(13)14/h5-7,12,14-15H,4,8-11H2,1-3H3 FWQJZNALGBTYNB-UHFFFAOYSA-N 50040158 9-Methoxy-2-methyl-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10561 5-hydroxytryptamine receptor 1A Homo sapiens 16 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040158 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040158&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266668 103972218 CHEMBL10561 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063636 COc1cccc2CC[C@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50040166 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL418705 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266613 103972226 CHEMBL418705 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063637 CN1CCc2cccc-3c2[C@H]1Cc4c3c(c(cc4)O)O InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3 VMWNQDUVQKEIOC-UHFFFAOYSA-N 50001955 APOKYN::CHEMBL53::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::APOMORPHINE HYDROCHLORIDE::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::APOMORPHINE D(2) dopamine receptor Homo sapiens 26 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6005 103916308 CHEMBL53 DB00714 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063638 CCCN1CCC2[C@@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3 HPUKPOAWHHZLIX-UHFFFAOYSA-N 50040167 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL267812 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10332127 103972227 CHEMBL267812 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063639 CCCN1CCC2[C@@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3 HPUKPOAWHHZLIX-UHFFFAOYSA-N 50040167 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL267812 5-hydroxytryptamine receptor 1A Homo sapiens 186 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040167&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10332127 103972227 CHEMBL267812 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063640 COc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50040168 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL276825 D(2) dopamine receptor Homo sapiens >339 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040168 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266623 103972228 CHEMBL276825 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063643 COc1cccc2CC[C@@H]3C(CCN3CCc3ccccc3)c12 InChI=1S/C21H25NO/c1-23-20-9-5-8-17-10-11-19-18(21(17)20)13-15-22(19)14-12-16-6-3-2-4-7-16/h2-9,18-19H,10-15H2,1H3 PPFLJANGUQOHFJ-UHFFFAOYSA-N 50040169 9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL267086 5-hydroxytryptamine receptor 1A Homo sapiens >442 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040169 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040169&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266678 103972229 CHEMBL267086 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063644 COc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50040170 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10570 D(2) dopamine receptor Rattus norvegicus 42.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040170 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266689 103972230 CHEMBL10570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063645 CCCN1[C@@H](C)CC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C17H25NO/c1-4-10-18-12(2)11-14-15(18)9-8-13-6-5-7-16(19-3)17(13)14/h5-7,12,14-15H,4,8-11H2,1-3H3 FWQJZNALGBTYNB-UHFFFAOYSA-N 50040171 9-Methoxy-2-methyl-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL273614 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040171 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266676 103972231 CHEMBL273614 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063646 COc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50040170 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10570 D(2) dopamine receptor Homo sapiens 78.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040170 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266689 103972230 CHEMBL10570 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063648 CCCN1CCC2C1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3 UVOXCNCVSFLEPX-UHFFFAOYSA-N 50040173 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL9980 5-hydroxytryptamine receptor 1A Homo sapiens 1.4 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040173&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 14944886 103972233 CHEMBL9980 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063650 CCCN1CCC2[C@H]1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3 UVOXCNCVSFLEPX-UHFFFAOYSA-N 50040175 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL9979 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040175 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10059787 103972235 CHEMBL9979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063651 COc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50040168 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL276825 5-hydroxytryptamine receptor 1A Homo sapiens >333 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040168 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040168&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266623 103972228 CHEMBL276825 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063653 CCCN1CCC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3 HPUKPOAWHHZLIX-UHFFFAOYSA-N 50040176 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10714 5-hydroxytryptamine receptor 1A Homo sapiens 0.2 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040176&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10037522 103972236 CHEMBL10714 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063654 COc1cccc2CC[C@@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50040177 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10270 D(2) dopamine receptor Homo sapiens 6.7 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266664 103972237 CHEMBL10270 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063656 COc1cccc2CC[C@H]3C(CCN3CCc3ccccc3)c12 InChI=1S/C21H25NO/c1-23-20-9-5-8-17-10-11-19-18(21(17)20)13-15-22(19)14-12-16-6-3-2-4-7-16/h2-9,18-19H,10-15H2,1H3 PPFLJANGUQOHFJ-UHFFFAOYSA-N 50040178 9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL416519 5-hydroxytryptamine receptor 1A Homo sapiens 317 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040178 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040178&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266611 103972238 CHEMBL416519 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063658 COc1cccc2CC[C@@H]3C(CCN3CCc3ccccc3)c12 InChI=1S/C21H25NO/c1-23-20-9-5-8-17-10-11-19-18(21(17)20)13-15-22(19)14-12-16-6-3-2-4-7-16/h2-9,18-19H,10-15H2,1H3 PPFLJANGUQOHFJ-UHFFFAOYSA-N 50040169 9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL267086 D(2) dopamine receptor Homo sapiens >339 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040169 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266678 103972229 CHEMBL267086 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063659 COc1cccc2CC[C@H]3C(CCN3CCc3ccccc3)c12 InChI=1S/C21H25NO/c1-23-20-9-5-8-17-10-11-19-18(21(17)20)13-15-22(19)14-12-16-6-3-2-4-7-16/h2-9,18-19H,10-15H2,1H3 PPFLJANGUQOHFJ-UHFFFAOYSA-N 50040178 9-Methoxy-3-phenethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL416519 D(2) dopamine receptor Homo sapiens 392 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040178 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266611 103972238 CHEMBL416519 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063662 COc1cccc2CC[C@@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50040177 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10270 D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040177 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266664 103972237 CHEMBL10270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063663 Oc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040179 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL275543 D(2) dopamine receptor Homo sapiens 59 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040179 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266663 103972239 CHEMBL275543 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063664 CCCN1CCC2C1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3 HPUKPOAWHHZLIX-UHFFFAOYSA-N 50040181 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10677 5-hydroxytryptamine receptor 1A Homo sapiens 4.4 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040181 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040181&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 18988846 103972241 CHEMBL10677 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063668 CN(C)CCCN1c2ccccc2Sc3c1cc(cc3)Cl InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::THORAZINE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::CHEMBL71::CHLORPROMAZINE HYDROCHLORIDE::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::chloropromazine::PROMAPAR::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::SONAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3APX,3LK0,4MA8,5G08,5LG3,5NUJ,5NUK,5NUM,5NUN,7OOK 2726 103916255 CHEMBL71 DB00477 C06906 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063669 Oc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040179 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL275543 D(2) dopamine receptor Rattus norvegicus 259 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040179 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266663 103972239 CHEMBL275543 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063672 CCCN1CCC2[C@@H]1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3 UVOXCNCVSFLEPX-UHFFFAOYSA-N 50040161 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL276185 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040161 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014136 103972221 CHEMBL276185 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063673 Oc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040165 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10408 D(2) dopamine receptor Homo sapiens 108 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040165 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266677 103972225 CHEMBL10408 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063676 CCCN1CCC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3 HPUKPOAWHHZLIX-UHFFFAOYSA-N 50040176 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10714 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037522 103972236 CHEMBL10714 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063677 CN(C)CCCN1c2ccccc2Sc3c1cc(cc3)Cl InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::THORAZINE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::CHEMBL71::CHLORPROMAZINE HYDROCHLORIDE::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::chloropromazine::PROMAPAR::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::SONAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE::med.21724, Compound 15 5-hydroxytryptamine receptor 1A Homo sapiens 673.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search Z80 3APX,3LK0,4MA8,5G08,5LG3,5NUJ,5NUK,5NUM,5NUN,7OOK 2726 103916255 CHEMBL71 DB00477 C06906 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063680 CCCN1CCC2C1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3 UVOXCNCVSFLEPX-UHFFFAOYSA-N 50040173 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL9980 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944886 103972233 CHEMBL9980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063683 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 cid_1220::CHEMBL56::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL505765::DPAT::8-OH-DPAT,(-)::8-OH-DPAT,(+)::8-OH-DPAT::8-hydroxy-N,N-dipropylaminotetralin::8-Hydroxy-2-(di-n-propylamino)tetralin::CHEMBL1788118::[3H]-8-OH-DPAT::US10562853, Compound 8-OH-DPAT D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 CHEMBL1788118CHEMBL505765CHEMBL56 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063688 COc1cccc2CC[C@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50040166 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL418705 5-hydroxytryptamine receptor 1A Homo sapiens 49 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040166&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266613 103972226 CHEMBL418705 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063690 CCCN1CCC2[C@H]1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3 UVOXCNCVSFLEPX-UHFFFAOYSA-N 50040175 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL9979 5-hydroxytryptamine receptor 1A Homo sapiens 0.1 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040175 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040175&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10059787 103972235 CHEMBL9979 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063695 Oc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040165 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10408 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040165 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266677 103972225 CHEMBL10408 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063698 COc1cccc2CC[C@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50040166 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL418705 D(2) dopamine receptor Homo sapiens 77 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040166 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266613 103972226 CHEMBL418705 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063699 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 cid_1220::CHEMBL56::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL505765::DPAT::8-OH-DPAT,(-)::8-OH-DPAT,(+)::8-OH-DPAT::8-hydroxy-N,N-dipropylaminotetralin::8-Hydroxy-2-(di-n-propylamino)tetralin::CHEMBL1788118::[3H]-8-OH-DPAT::US10562853, Compound 8-OH-DPAT D(2) dopamine receptor Homo sapiens 86 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5866&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 CHEMBL1788118CHEMBL505765CHEMBL56 1 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BSB,9BS9,8IRS,7JVR,8U02,8TZQ D(2) dopamine receptor DRD2_HUMAN P14416 Q9NZR3 Q9UPA9 N/A A0A024R3C5 50063700 Oc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040179 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL275543 5-hydroxytryptamine receptor 1A Homo sapiens >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040179 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040179&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266663 103972239 CHEMBL275543 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063701 COc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50040170 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10570 5-hydroxytryptamine receptor 1A Homo sapiens 236 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040170 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040170&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266689 103972230 CHEMBL10570 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063706 CCCN1[C@@H](C)CC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C17H25NO/c1-4-10-18-12(2)11-14-15(18)9-8-13-6-5-7-16(19-3)17(13)14/h5-7,12,14-15H,4,8-11H2,1-3H3 FWQJZNALGBTYNB-UHFFFAOYSA-N 50040171 9-Methoxy-2-methyl-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL273614 5-hydroxytryptamine receptor 1A Homo sapiens 1 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040171 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=493&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040171&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 44266676 103972231 CHEMBL273614 1 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 5-hydroxytryptamine receptor 1A 5HT1A_HUMAN P08908 Q6LAE7 50063712 CCCN1CCC2C1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3 HPUKPOAWHHZLIX-UHFFFAOYSA-N 50040181 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10677 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040181 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18988846 103972241 CHEMBL10677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992317 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50034330 (3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 5-hydroxytryptamine receptor 1A Mus musculus 0.4 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7880&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 1 MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 8JSP 5-hydroxytryptamine receptor 1A 5HT1A_MOUSE Q64264 Q60956 Q61617 Q8BGS4 50992318 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 5-hydroxytryptamine receptor 1A Mus musculus 3.7 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7880&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 1 MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 8JSP 5-hydroxytryptamine receptor 1A 5HT1A_MOUSE Q64264 Q60956 Q61617 Q8BGS4 50992319 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3 ZRAGXRIXRXDXCR-UHFFFAOYSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 5-hydroxytryptamine receptor 1A Mus musculus >333 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG 5/24/1993 11/10/2009 Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7880&target=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=5-hydroxytryptamine+receptor+1A&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 1 MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 8JSP 5-hydroxytryptamine receptor 1A 5HT1A_MOUSE Q64264 Q60956 Q61617 Q8BGS4