BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50038386 CC(=O)N[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C22H37N9O8S2/c1-10(32)28-13-9-40-41-22(2,3)16(17(23)36)31-19(38)12(7-15(34)35)29-14(33)8-27-18(37)11(30-20(13)39)5-4-6-26-21(24)25/h11-13,16H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26) FWEONMXPHGWDHS-UHFFFAOYSA-N 50421884 CHEMBL2110309 Integrin alpha-IIb/beta-3 Homo sapiens 3000 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421884 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421884&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 15088321 164150759 CHEMBL2110309 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065034 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C1=O InChI=1S/C26H31N7O6S2/c1-33-18(9-6-12-29-26(27)28)24(38)30-14-21(34)31-17(13-22(35)36)23(37)32-16-8-3-5-11-20(16)41-40-19-10-4-2-7-15(19)25(33)39/h2-5,7-8,10-11,17-18H,6,9,12-14H2,1H3,(H,30,38)(H,31,34)(H,32,37)(H,35,36)(H4,27,28,29) YITSCMGHJOGUNC-UHFFFAOYSA-N 50040737 [(7R,13R)-13-(3-Guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid::CHEMBL165266 Integrin alpha-IIb/beta-3 Homo sapiens 2.6 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040737 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040737&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378558 103972750 CHEMBL165266 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065035 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C(=O)N2CCC[C@H]2C1=O InChI=1S/C31H38N8O7S2/c1-38-21(10-6-14-34-31(32)33)28(44)35-17-25(40)36-20(16-26(41)42)27(43)37-19-9-3-5-13-24(19)48-47-23-12-4-2-8-18(23)29(45)39-15-7-11-22(39)30(38)46/h2-5,8-9,12-13,20-22H,6-7,10-11,14-17H2,1H3,(H,35,44)(H,36,40)(H,37,43)(H,41,42)(H4,32,33,34) PJJPYAYJKNOWGX-UHFFFAOYSA-N 50040739 Cyclo-S-S[Mba-P(Ne-Me)RGD-Man]::CHEMBL165211 Integrin alpha-IIb/beta-3 Homo sapiens 820.0 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040739 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040739&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378224 103972752 CHEMBL165211 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065036 CC(=O)N[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)N(Cc2ccccc2)C1=O)C(N)=O InChI=1S/C29H43N9O8S2/c1-16(39)35-19-15-47-48-29(2,3)23(24(30)43)37-25(44)18(12-22(41)42)36-21(40)13-34-26(45)20(10-7-11-33-28(31)32)38(27(19)46)14-17-8-5-4-6-9-17/h4-6,8-9,18-20,23H,7,10-15H2,1-3H3,(H2,30,43)(H,34,45)(H,35,39)(H,36,40)(H,37,44)(H,41,42)(H4,31,32,33) TWSSIANDVAXPNW-UHFFFAOYSA-N 50040738 [(4S,7R,13R,16S)-16-Acetylamino-14-benzyl-4-carbamoyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL165153 Integrin alpha-IIb/beta-3 Homo sapiens >100000 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040738 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040738&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378360 103972751 CHEMBL165153 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065037 CN1CC(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C1=O InChI=1S/C25H42N10O9S2/c1-12(36)31-15-11-45-46-25(2,3)19(20(26)41)34-22(43)14(8-18(39)40)33-16(37)9-30-21(42)13(6-5-7-29-24(27)28)32-17(38)10-35(4)23(15)44/h13-15,19H,5-11H2,1-4H3,(H2,26,41)(H,30,42)(H,31,36)(H,32,38)(H,33,37)(H,34,43)(H,39,40)(H4,27,28,29) ULFNTEAQLOBMSH-UHFFFAOYSA-N 50040740 [(4S,7R,13R,19S)-19-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,17-trimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-7-yl]-acetic acid::CHEMBL349143 Integrin alpha-IIb/beta-3 Homo sapiens 77.0 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040740 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040740&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378584 103972753 CHEMBL349143 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065038 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)NCCSSc2ccccc2C1=O InChI=1S/C22H31N7O6S2/c1-29-15(6-4-8-26-22(23)24)20(34)27-12-17(30)28-14(11-18(31)32)19(33)25-9-10-36-37-16-7-3-2-5-13(16)21(29)35/h2-3,5,7,14-15H,4,6,8-12H2,1H3,(H,25,33)(H,27,34)(H,28,30)(H,31,32)(H4,23,24,26) CEKNHWXPXHFXSX-UHFFFAOYSA-N 50040742 [(11R,17R)-17-(3-Guanidino-propyl)-18-methyl-10,13,16,19-tetraoxo-7,8,9,10,12,13,14,15,16,17,18,19-dodecahydro-11H-5,6-dithia-9,12,15,18-tetraaza-benzocycloheptadecen-11-yl]-acetic acid::CHEMBL165459 Integrin alpha-IIb/beta-3 Homo sapiens 9.5 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040742 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040742&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378320 103972755 CHEMBL165459 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065039 CCN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C1=O InChI=1S/C24H41N9O8S2/c1-5-33-15(7-6-8-28-23(26)27)21(40)29-10-16(35)31-13(9-17(36)37)20(39)32-18(19(25)38)24(3,4)43-42-11-14(22(33)41)30-12(2)34/h13-15,18H,5-11H2,1-4H3,(H2,25,38)(H,29,40)(H,30,34)(H,31,35)(H,32,39)(H,36,37)(H4,26,27,28) LJTLOQLGXVVLML-UHFFFAOYSA-N 50040746 [(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-14-ethyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL262519 Integrin alpha-IIb/beta-3 Homo sapiens 65 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040746 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040746&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378222 103972759 CHEMBL262519 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065040 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C1=O InChI=1S/C26H31N7O6S2/c1-33-18(9-6-12-29-26(27)28)24(38)30-14-21(34)31-17(13-22(35)36)23(37)32-16-8-3-5-11-20(16)41-40-19-10-4-2-7-15(19)25(33)39/h2-5,7-8,10-11,17-18H,6,9,12-14H2,1H3,(H,30,38)(H,31,34)(H,32,37)(H,35,36)(H4,27,28,29) YITSCMGHJOGUNC-UHFFFAOYSA-N 50040745 [(7S,13R)-13-(3-Guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid::CHEMBL164078 Integrin alpha-IIb/beta-3 Homo sapiens 8750 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040745 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040745&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 10348588 103972758 CHEMBL164078 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065041 CN1[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C1=O InChI=1S/C26H31N7O6S2/c1-33-18(9-6-12-29-26(27)28)24(38)30-14-21(34)31-17(13-22(35)36)23(37)32-16-8-3-5-11-20(16)41-40-19-10-4-2-7-15(19)25(33)39/h2-5,7-8,10-11,17-18H,6,9,12-14H2,1H3,(H,30,38)(H,31,34)(H,32,37)(H,35,36)(H4,27,28,29) YITSCMGHJOGUNC-UHFFFAOYSA-N 50040741 [(7R,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid::CHEMBL349194 Integrin alpha-IIb/beta-3 Homo sapiens 20 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040741 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040741&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 10348589 103972754 CHEMBL349194 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065042 CN1[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)N(C)[C@H](CCCNC(N)=N)C(=O)NCC1=O InChI=1S/C24H41N9O8S2/c1-12(34)30-13-11-42-43-24(2,3)18(19(25)38)31-21(40)15(9-17(36)37)32(4)16(35)10-29-20(39)14(33(5)22(13)41)7-6-8-28-23(26)27/h13-15,18H,6-11H2,1-5H3,(H2,25,38)(H,29,39)(H,30,34)(H,31,40)(H,36,37)(H4,26,27,28) PZVAWHXHLFQUNC-UHFFFAOYSA-N 50040748 [(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,8,14-tetramethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL438170 Integrin alpha-IIb/beta-3 Homo sapiens 7040 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040748 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040748&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378336 103972761 CHEMBL438170 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065043 [#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#16]-[#16]C([#6])([#6])[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7](-[#6])-[#6]-1=O)-[#6](-[#7])=O InChI=1S/C26H4N9O8S2/c1-5-6-9-17(36)33-15-13-44-45-26(2,3)20(21(27)40)34-22(41)14(11-19(38)39)32-18(37)12-31-23(42)16(35(4)24(15)43)8-7-10-30-25(28)29/h14-16,20H YXYAVWVVZZLZAY-UHFFFAOYSA-N 50040735 [(7S,13S,16R)-4-Carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-16-pentanoylamino-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL2371469 Integrin alpha-IIb/beta-3 Homo sapiens 26 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040735 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040735&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73354661 103972748 CHEMBL2371469 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065044 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)N2CCC[C@H]2C1=O InChI=1S/C28H46N10O9S2/c1-14(39)34-16-13-48-49-28(2,3)21(22(29)43)36-23(44)15(11-20(41)42)35-19(40)12-33-24(45)17(7-5-9-32-27(30)31)37(4)26(47)18-8-6-10-38(18)25(16)46/h15-18,21H,5-13H2,1-4H3,(H2,29,43)(H,33,45)(H,34,39)(H,35,40)(H,36,44)(H,41,42)(H4,30,31,32) WWZDAWHXSPWQFH-UHFFFAOYSA-N 50040736 [(5S,10S,13R,19R,21aS)-5-Acetylamino-10-carbamoyl-19-(3-guanidino-propyl)-9,9,20-trimethyl-4,12,15,18,21-pentaoxo-octadecahydro-7,8-dithia-3a,11,14,17,20-pentaaza-cyclopentacycloicosen-13-yl]-acetic acid::CHEMBL424178 Integrin alpha-IIb/beta-3 Homo sapiens >10000 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040736 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040736&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378302 103972749 CHEMBL424178 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065045 [#6]-[#7]-1-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6](-[#7])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-c2ccccc2)-[#6]-1=O InChI=1S/C28H9N9O8S2/c1-28(2)21(22(29)41)36-24(43)16(12-20(39)40)34-19(38)13-33-25(44)18(10-7-11-32-27(30)31)37(3)26(45)17(14-46-47-28)35-23(42)15-8-5-4-6-9-15/h4-6,8-9,16-18,21H DDNGKRDQINWQPB-UHFFFAOYSA-N 50040750 [(7S,13S,16R)-16-Benzoylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL2371446 Integrin alpha-IIb/beta-3 Homo sapiens 13.7 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040750 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040750&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73347079 103972763 CHEMBL2371446 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065046 CC(=O)N[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C22H37N9O8S2/c1-10(32)28-13-9-40-41-22(2,3)16(17(23)36)31-19(38)12(7-15(34)35)29-14(33)8-27-18(37)11(30-20(13)39)5-4-6-26-21(24)25/h11-13,16H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26) FWEONMXPHGWDHS-UHFFFAOYSA-N 50040751 [(4S,7S,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL351938 Integrin alpha-IIb/beta-3 Homo sapiens >1000000 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040751 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040751&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 15088322 103972764 CHEMBL351938 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065047 [#6]-[#6](-[#16])-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#16]-[#16]C([#6])([#6])[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7](-[#6])-[#6]-1=O)-[#6](-[#7])=O InChI=1S/C24H4N9O8S3/c1-11(42)19(38)31-13-10-43-44-24(2,3)17(18(25)37)32-20(39)12(8-16(35)36)30-15(34)9-29-21(40)14(33(4)22(13)41)6-5-7-28-23(26)27/h12-14,17H DHOGUPWBMAGBOA-UHFFFAOYSA-N 50040753 [(7S,13S,16R)-4-Carbamoyl-13-(3-guanidino-propyl)-16-(2-mercapto-propionylamino)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL2371459 Integrin alpha-IIb/beta-3 Homo sapiens 24.3 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040753 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040753&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73350172 103972766 CHEMBL2371459 C01525 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065048 CC(=O)N[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC(=O)CNC1=O)C(N)=O InChI=1S/C24H40N10O9S2/c1-11(35)31-14-10-44-45-24(2,3)18(19(25)40)34-22(43)13(7-17(38)39)33-16(37)9-29-20(41)12(5-4-6-28-23(26)27)32-15(36)8-30-21(14)42/h12-14,18H,4-10H2,1-3H3,(H2,25,40)(H,29,41)(H,30,42)(H,31,35)(H,32,36)(H,33,37)(H,34,43)(H,38,39)(H4,26,27,28) FIQNCGYYFPFAIP-UHFFFAOYSA-N 50040754 [(4S,7R,13R,19S)-19-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-7-yl]-acetic acid::CHEMBL164818 Integrin alpha-IIb/beta-3 Homo sapiens 610 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040754 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040754&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378585 103972767 CHEMBL164818 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065049 [#6]-[#7]-1-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6](-[#8])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](-[#6])=O)-[#6]-1=O InChI=1S/C23H4N8O9S2/c1-11(32)28-13-10-41-42-23(2,3)17(21(39)40)30-18(36)12(8-16(34)35)29-15(33)9-27-19(37)14(31(4)20(13)38)6-5-7-26-22(24)25/h12-14,17H HSBMDAJZJKNSCF-UHFFFAOYSA-N 50040755 (7S,13S,16R)-16-Acetylamino-7-carboxymethyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadecane-4-carboxylic acid::CHEMBL2371466 Integrin alpha-IIb/beta-3 Homo sapiens 8.5 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040755 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040755&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73353139 103972768 CHEMBL2371466 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065050 NC(=N)NCCC[C@H]1NC(=O)c2ccccc2SSc2ccccc2NC(=O)[C@@H](CC(O)=O)NC(=O)CNC1=O InChI=1S/C25H29N7O6S2/c26-25(27)28-11-5-8-16-23(37)29-13-20(33)30-17(12-21(34)35)24(38)31-15-7-2-4-10-19(15)40-39-18-9-3-1-6-14(18)22(36)32-16/h1-4,6-7,9-10,16-17H,5,8,11-13H2,(H,29,37)(H,30,33)(H,31,38)(H,32,36)(H,34,35)(H4,26,27,28) HJMWYGPOMVSGID-UHFFFAOYSA-N 50040756 [(7R,13R)-13-(3-Guanidino-propyl)-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid::CHEMBL350724 Integrin alpha-IIb/beta-3 Homo sapiens 27 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040756 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040756&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378307 103972769 CHEMBL350724 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065051 CN1CC(=O)N(C)[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C1=O InChI=1S/C26H44N10O9S2/c1-13(37)32-15-12-46-47-26(2,3)20(21(27)42)34-22(43)14(9-19(40)41)33-17(38)10-31-23(44)16(7-6-8-30-25(28)29)36(5)18(39)11-35(4)24(15)45/h14-16,20H,6-12H2,1-5H3,(H2,27,42)(H,31,44)(H,32,37)(H,33,38)(H,34,43)(H,40,41)(H4,28,29,30) IREXQQUAADPBFC-UHFFFAOYSA-N 50040760 [(4S,7R,13R,19S)-19-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14,17-tetramethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-7-yl]-acetic acid::CHEMBL355861 Integrin alpha-IIb/beta-3 Homo sapiens 20 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040760 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040760&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378401 103972773 CHEMBL355861 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065052 CN([C@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O)C(C)=O InChI=1S/C23H39N9O8S2/c1-11(33)32(4)14-10-41-42-23(2,3)17(18(24)37)31-20(39)13(8-16(35)36)29-15(34)9-28-19(38)12(30-21(14)40)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,38)(H,29,34)(H,30,40)(H,31,39)(H,35,36)(H4,25,26,27) OPUMTHQIMPJUMU-UHFFFAOYSA-N 50040764 [(4S,7R,13R,16R)-16-(Acetyl-methyl-amino)-4-carbamoyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL351083 Integrin alpha-IIb/beta-3 Homo sapiens 110 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040764 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040764&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378089 103972777 CHEMBL351083 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065053 [#6]-[#7]-1-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6](-[#7])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](-[#6])=O)-[#6]-1=O InChI=1S/C23H4N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H PICRLIGYFMUORU-UHFFFAOYSA-N 50040762 [(7S,13S,16R)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL2371456 Integrin alpha-IIb/beta-3 Homo sapiens 58.0 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040762 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040762&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73354659 103972775 CHEMBL2371456 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065054 [#6]-[#7]-1-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6](-[#7])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7])-[#6]-1=O InChI=1S/C21H4N9O7S2/c1-21(2)15(16(23)34)29-17(35)11(7-14(32)33)28-13(31)8-27-18(36)12(5-4-6-26-20(24)25)30(3)19(37)10(22)9-38-39-21/h10-12,15H HROGNZXQLPWKHD-UHFFFAOYSA-N 50040752 [(7S,13S,16R)-16-Amino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL2371457 Integrin alpha-IIb/beta-3 Homo sapiens 9.3 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040752 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040752&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73354660 103972765 CHEMBL2371457 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065055 [#6]-[#7]-1-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6](-[#7])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6]-[#6](=O)-c2ccccc2)-[#6]-1=O InChI=1S/C29H9N9O8S2/c1-29(2)23(24(30)43)37-25(44)17(12-22(41)42)36-21(40)14-35-26(45)19(10-7-11-33-28(31)32)38(3)27(46)18(15-47-48-29)34-13-20(39)16-8-5-4-6-9-16/h4-6,8-9,17-19,23H CCKIODUHKIXDNM-UHFFFAOYSA-N 50040767 [(7S,13S,16R)-4-Carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-16-(2-oxo-2-phenyl-ethylamino)-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL2371468 Integrin alpha-IIb/beta-3 Homo sapiens 35 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040767 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040767&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73350174 103972780 CHEMBL2371468 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065056 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)Nc2ccccc2SSC[C@@H](NC(C)=O)C1=O InChI=1S/C24H34N8O7S2/c1-13(33)29-16-12-40-41-18-8-4-3-6-14(18)31-21(37)15(10-20(35)36)30-19(34)11-28-22(38)17(32(2)23(16)39)7-5-9-27-24(25)26/h3-4,6,8,15-17H,5,7,9-12H2,1-2H3,(H,28,38)(H,29,33)(H,30,34)(H,31,37)(H,35,36)(H4,25,26,27) CRYDBXCBCUYLOS-UHFFFAOYSA-N 50040770 [(8S,11R,17R)-8-Acetylamino-11-(3-guanidino-propyl)-10-methyl-9,12,15,18-tetraoxo-8,9,10,11,12,13,14,15,16,17,18,19-dodecahydro-7H-5,6-dithia-10,13,16,19-tetraaza-benzocycloheptadecen-17-yl]-acetic acid::CHEMBL351640 Integrin alpha-IIb/beta-3 Homo sapiens 26 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040770 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040770&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378218 103972783 CHEMBL351640 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065058 CN1[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](SSC[C@H](NC(C)=O)C1=O)c1ccccc1)C(N)=O InChI=1S/C27H39N9O8S2/c1-14(37)33-17-13-45-46-22(15-7-4-3-5-8-15)21(23(28)41)35-24(42)16(11-20(39)40)34-19(38)12-32-25(43)18(36(2)26(17)44)9-6-10-31-27(29)30/h3-5,7-8,16-18,21-22H,6,9-13H2,1-2H3,(H2,28,41)(H,32,43)(H,33,37)(H,34,38)(H,35,42)(H,39,40)(H4,29,30,31) ZYOFMQCFYBMZGP-UHFFFAOYSA-N 50040765 [(3S,4R,7S,13S,16R)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-3-phenyl-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL168140 Integrin alpha-IIb/beta-3 Homo sapiens 45 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040765 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040765&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 10101088 103972778 CHEMBL168140 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065059 CC(=O)N[C@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C22H37N9O8S2/c1-10(32)28-13-9-40-41-22(2,3)16(17(23)36)31-19(38)12(7-15(34)35)29-14(33)8-27-18(37)11(30-20(13)39)5-4-6-26-21(24)25/h11-13,16H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26) FWEONMXPHGWDHS-UHFFFAOYSA-N 50040768 [(4S,7R,13R,16R)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL351514 Integrin alpha-IIb/beta-3 Homo sapiens 2650 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040768 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040768&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378106 103972781 CHEMBL351514 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065060 CN1CC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)N[C@H](CCCNC(N)=N)C1=O InChI=1S/C23H39N9O8S2/c1-11(33)28-14-10-41-42-23(2,3)17(18(24)37)31-19(38)13(8-16(35)36)29-15(34)9-32(4)21(40)12(30-20(14)39)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,33)(H,29,34)(H,30,39)(H,31,38)(H,35,36)(H4,25,26,27) PNNKIIFXOAKISH-UHFFFAOYSA-N 50040766 [(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,11-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL353203 Integrin alpha-IIb/beta-3 Homo sapiens 1250 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040766 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040766&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378378 103972779 CHEMBL353203 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065061 CN1CC(=O)N(C)[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C1=O InChI=1S/C29H36N8O7S2/c1-36-16-24(39)37(2)20(10-7-13-32-29(30)31)27(43)33-15-23(38)34-19(14-25(40)41)26(42)35-18-9-4-6-12-22(18)46-45-21-11-5-3-8-17(21)28(36)44/h3-6,8-9,11-12,19-20H,7,10,13-16H2,1-2H3,(H,33,43)(H,34,38)(H,35,42)(H,40,41)(H4,30,31,32) DYARGFKEZJCFFT-UHFFFAOYSA-N 50040771 [(12S,18S)-18-(3-Guanidino-propyl)-19,22-dimethyl-11,14,17,20,23-pentaoxo-2,3-dithia-10,13,16,19,22-pentaaza-tricyclo[22.4.0.0*4,9*]octacosa-1(28),4(9),5,7,24,26-hexaen-12-yl]-acetic acid::CHEMBL165212 Integrin alpha-IIb/beta-3 Homo sapiens 24.5 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040771 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040771&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 10394724 103972784 CHEMBL165212 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065062 [#6]-[#7]-1-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6](-[#8])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7])-[#6]-1=O InChI=1S/C21H4N8O8S2/c1-21(2)15(19(36)37)28-16(33)11(7-14(31)32)27-13(30)8-26-17(34)12(5-4-6-25-20(23)24)29(3)18(35)10(22)9-38-39-21/h10-12,15H UUUFJGPDJVBOCJ-UHFFFAOYSA-N 50040769 (7S,13S,16R)-16-Amino-7-carboxymethyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadecane-4-carboxylic acid::CHEMBL2371467 Integrin alpha-IIb/beta-3 Homo sapiens 4.8 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040769 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040769&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73348588 103972782 CHEMBL2371467 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065063 CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C14H25N7O6/c1-7(22)20-8(3-2-4-18-14(16)17)13(27)19-6-10(23)21-9(12(15)26)5-11(24)25/h8-9H,2-6H2,1H3,(H2,15,26)(H,19,27)(H,20,22)(H,21,23)(H,24,25)(H4,16,17,18) UCYDPZZDAXVXAG-UHFFFAOYSA-N 50010174 CHEMBL104534::3-[4-amino(imino)methylamino-1-methylcarboxamido-(1S)-butylcarboxamidomethylcarboxamido]-3-carbamoylpropanoic acid::Ac-RGD-NH2 Integrin alpha-IIb/beta-3 Homo sapiens 4200 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010174 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010174&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 15088315 103923045 CHEMBL104534 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065064 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC(C)(C)[C@@H](NC(C)=O)C1=O InChI=1S/C25H43N9O8S2/c1-12(35)31-18-22(42)34(6)14(8-7-9-29-23(27)28)21(41)30-11-15(36)32-13(10-16(37)38)20(40)33-17(19(26)39)24(2,3)43-44-25(18,4)5/h13-14,17-18H,7-11H2,1-6H3,(H2,26,39)(H,30,41)(H,31,35)(H,32,36)(H,33,40)(H,37,38)(H4,27,28,29) FTNKTQMIRUQUMO-UHFFFAOYSA-N 50040761 [(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14,17,17-pentamethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL164427 Integrin alpha-IIb/beta-3 Homo sapiens 2.5 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040761 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040761&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378331 103972774 CHEMBL164427 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065065 [#6]-[#7]-1-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6](-[#7])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](-[#6])=O)-[#6]-1=O InChI=1S/C23H4N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H PICRLIGYFMUORU-UHFFFAOYSA-N 50040762 [(7S,13S,16R)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL2371456 Integrin alpha-IIb/beta-3 Homo sapiens 58 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040762 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040762&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 73354659 103972775 CHEMBL2371456 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065066 CN1[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@H](SSC[C@H](NC(C)=O)C1=O)c1ccccc1)C(N)=O InChI=1S/C27H39N9O8S2/c1-14(37)33-17-13-45-46-22(15-7-4-3-5-8-15)21(23(28)41)35-24(42)16(11-20(39)40)34-19(38)12-32-25(43)18(36(2)26(17)44)9-6-10-31-27(29)30/h3-5,7-8,16-18,21-22H,6,9-13H2,1-2H3,(H2,28,41)(H,32,43)(H,33,37)(H,34,38)(H,35,42)(H,39,40)(H4,29,30,31) ZYOFMQCFYBMZGP-UHFFFAOYSA-N 50040763 [(3R,4R,7S,13S,16R)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-3-phenyl-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL349052 Integrin alpha-IIb/beta-3 Homo sapiens 125 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040763 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040763&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 10484706 103972776 CHEMBL349052 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065067 CN1CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C1=O InChI=1S/C28H34N8O7S2/c1-36-15-23(38)33-18(9-6-12-31-28(29)30)25(41)32-14-22(37)34-19(13-24(39)40)26(42)35-17-8-3-5-11-21(17)45-44-20-10-4-2-7-16(20)27(36)43/h2-5,7-8,10-11,18-19H,6,9,12-15H2,1H3,(H,32,41)(H,33,38)(H,34,37)(H,35,42)(H,39,40)(H4,29,30,31) GZKOYPGOEKDKDD-UHFFFAOYSA-N 50040775 [(12S,18S)-18-(3-Guanidino-propyl)-22-methyl-11,14,17,20,23-pentaoxo-2,3-dithia-10,13,16,19,22-pentaaza-tricyclo[22.4.0.0*4,9*]octacosa-1(28),4(9),5,7,24,26-hexaen-12-yl]-acetic acid::CHEMBL164670 Integrin alpha-IIb/beta-3 Homo sapiens 143 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040775 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040775&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 10439316 103972787 CHEMBL164670 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065068 CN1CC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)N(C)[C@H](CCCNC(N)=N)C1=O InChI=1S/C24H41N9O8S2/c1-12(34)29-14-11-42-43-24(2,3)18(19(25)38)31-20(39)13(9-17(36)37)30-16(35)10-32(4)22(41)15(33(5)21(14)40)7-6-8-28-23(26)27/h13-15,18H,6-11H2,1-5H3,(H2,25,38)(H,29,34)(H,30,35)(H,31,39)(H,36,37)(H4,26,27,28) YZWVESBWHOALGF-UHFFFAOYSA-N 50040743 [(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,11,14-tetramethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL424017 Integrin alpha-IIb/beta-3 Homo sapiens 15100 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040743 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040743&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378327 103972756 CHEMBL424017 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065069 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)N(Cc2ccccc2)CC1=O InChI=1S/C32H48N10O9S2/c1-18(43)38-21-17-52-53-32(2,3)26(27(33)48)40-28(49)20(13-25(46)47)39-23(44)14-37-29(50)22(11-8-12-36-31(34)35)41(4)24(45)16-42(30(21)51)15-19-9-6-5-7-10-19/h5-7,9-10,20-22,26H,8,11-17H2,1-4H3,(H2,33,48)(H,37,50)(H,38,43)(H,39,44)(H,40,49)(H,46,47)(H4,34,35,36) KHEPTFKEYMTFHE-UHFFFAOYSA-N 50040776 [(4S,7R,13R,19S)-19-Acetylamino-17-benzyl-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-7-yl]-acetic acid::CHEMBL167575 Integrin alpha-IIb/beta-3 Homo sapiens 430.0 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040776 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040776&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378400 103972788 CHEMBL167575 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065070 CC(=O)N[C@@H]1CSSc2ccccc2NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O InChI=1S/C23H32N8O7S2/c1-12(32)28-16-11-39-40-17-7-3-2-5-13(17)30-21(37)15(9-19(34)35)29-18(33)10-27-20(36)14(31-22(16)38)6-4-8-26-23(24)25/h2-3,5,7,14-16H,4,6,8-11H2,1H3,(H,27,36)(H,28,32)(H,29,33)(H,30,37)(H,31,38)(H,34,35)(H4,24,25,26) WCNVKZMMWSNHOH-UHFFFAOYSA-N 50040758 [(8S,11R,17R)-8-Acetylamino-11-(3-guanidino-propyl)-9,12,15,18-tetraoxo-8,9,10,11,12,13,14,15,16,17,18,19-dodecahydro-7H-5,6-dithia-10,13,16,19-tetraaza-benzocycloheptadecen-17-yl]-acetic acid::CHEMBL350185 Integrin alpha-IIb/beta-3 Homo sapiens 280 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040758 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040758&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378361 103972771 CHEMBL350185 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065071 CC(=O)N[C@H]1C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CSSC1(C)C)C(N)=O InChI=1S/C22H37N9O8S2/c1-10(32)28-16-20(39)30-11(5-4-6-26-21(24)25)18(37)27-8-14(33)29-12(7-15(34)35)19(38)31-13(17(23)36)9-40-41-22(16,2)3/h11-13,16H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26) WSGHBTUCTZOPOJ-UHFFFAOYSA-N 50040757 [(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-17,17-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL354319 Integrin alpha-IIb/beta-3 Homo sapiens 188 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040757 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040757&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378494 103972770 CHEMBL354319 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065072 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)NCC1=O InChI=1S/C25H42N10O9S2/c1-12(36)32-14-11-45-46-25(2,3)19(20(26)41)34-22(43)13(8-18(39)40)33-16(37)9-30-23(44)15(6-5-7-29-24(27)28)35(4)17(38)10-31-21(14)42/h13-15,19H,5-11H2,1-4H3,(H2,26,41)(H,30,44)(H,31,42)(H,32,36)(H,33,37)(H,34,43)(H,39,40)(H4,27,28,29) UFZOBXGMWKOREI-UHFFFAOYSA-N 50040773 [(4S,7R,13R,19S)-19-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicos-7-yl]-acetic acid::CHEMBL163965 Integrin alpha-IIb/beta-3 Homo sapiens 135 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040773 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040773&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378583 103972785 CHEMBL163965 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065073 CN1[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@H](SSC[C@H](NC(C)=O)C1=O)c1ccccc1)C(O)=O InChI=1S/C27H38N8O9S2/c1-14(36)32-17-13-45-46-22(15-7-4-3-5-8-15)21(26(43)44)34-23(40)16(11-20(38)39)33-19(37)12-31-24(41)18(35(2)25(17)42)9-6-10-30-27(28)29/h3-5,7-8,16-18,21-22H,6,9-13H2,1-2H3,(H,31,41)(H,32,36)(H,33,37)(H,34,40)(H,38,39)(H,43,44)(H4,28,29,30) UAPVZXWNLBOZAW-UHFFFAOYSA-N 50040747 (3R,4R,7S,13S,16R)-16-Acetylamino-7-carboxymethyl-13-(3-guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-3-phenyl-1,2-dithia-5,8,11,14-tetraaza-cycloheptadecane-4-carboxylic acid::CHEMBL165488 Integrin alpha-IIb/beta-3 Homo sapiens 2.1 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040747 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040747&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378195 103972760 CHEMBL165488 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065074 CC(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C20H33N9O8S2/c1-9(30)26-13-8-39-38-7-12(16(21)34)29-18(36)11(5-15(32)33)27-14(31)6-25-17(35)10(28-19(13)37)3-2-4-24-20(22)23/h10-13H,2-8H2,1H3,(H2,21,34)(H,25,35)(H,26,30)(H,27,31)(H,28,37)(H,29,36)(H,32,33)(H4,22,23,24) IDMAZMUTHNEQSS-UHFFFAOYSA-N 50010176 CHEMBL107009::[16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::[(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid Integrin alpha-IIb/beta-3 Homo sapiens 780.0 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010176 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010176&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44336218 103923047 CHEMBL107009 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065075 CC(=O)N[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C22H37N9O8S2/c1-10(32)28-13-9-40-41-22(2,3)16(17(23)36)31-19(38)12(7-15(34)35)29-14(33)8-27-18(37)11(30-20(13)39)5-4-6-26-21(24)25/h11-13,16H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26) FWEONMXPHGWDHS-UHFFFAOYSA-N 50040759 [(4S,7R,13S,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3-dimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL164514 Integrin alpha-IIb/beta-3 Homo sapiens 720 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040759 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040759&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 15088323 103972772 CHEMBL164514 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065076 CN1[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC1=O InChI=1S/C23H39N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-21(40)14(8-16(35)36)32(4)15(34)9-28-19(38)12(30-20(13)39)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,38)(H,29,33)(H,30,39)(H,31,40)(H,35,36)(H4,25,26,27) MKPMQEYJIVJVFI-UHFFFAOYSA-N 50040749 [(4S,7R,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,8-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL352467 Integrin alpha-IIb/beta-3 Homo sapiens 25300 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040749 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040749&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378223 103972762 CHEMBL352467 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065077 CN1[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C1=O InChI=1S/C23H39N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,39)(H,29,33)(H,30,34)(H,31,38)(H,35,36)(H4,25,26,27) MWLMZCNGBAIZSG-UHFFFAOYSA-N 50040774 [(4S,7R,13S,16S)-16-Acetylamino-4-carbamoyl-13-(3-guanidino-propyl)-3,3,14-trimethyl-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraaza-cycloheptadec-7-yl]-acetic acid::CHEMBL349056 Integrin alpha-IIb/beta-3 Homo sapiens 82 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040774 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040774&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378303 103972786 CHEMBL349056 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499 50065078 CN1[C@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C1=O InChI=1S/C26H31N7O6S2/c1-33-18(9-6-12-29-26(27)28)24(38)30-14-21(34)31-17(13-22(35)36)23(37)32-16-8-3-5-11-20(16)41-40-19-10-4-2-7-15(19)25(33)39/h2-5,7-8,10-11,17-18H,6,9,12-14H2,1H3,(H,30,38)(H,31,34)(H,32,37)(H,35,36)(H4,27,28,29) YITSCMGHJOGUNC-UHFFFAOYSA-N 50040737 [(7R,13R)-13-(3-Guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid::CHEMBL165266 Integrin alpha-IIb/beta-3 Homo sapiens 2.1 ChEMBL 10.1021/jm00032a009 10.7270/Q2445KJB 8145226 Ali, FE; Bennett, DB; Calvo, RR; Elliott, JD; Hwang, SM; Ku, TW; Lago, MA; Nichols, AJ; Romoff, TT; Shah, DH 5/4/1994 11/10/2009 Smithkline Beecham Pharmaceuticals Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040737 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000011&target=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040737&enzyme=Integrin+alpha-IIb%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 44378558 103972750 CHEMBL165266 2 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE 9E8C,9E8A,9AXL,8GCD,7LA4,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6V4P,4CAK,3FCS,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7TPD,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,3NIG,3NIF,3NID,3FCU,7U60,4Z7O,4Z7N,7UJE,7UBR,7U9V,7U9F,7TMZ,7THO,5HDB,4Z7Q,7TD8,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,2KNC,7SFT,2MTP,2K9J,2K1A,1S4W,1M8O,1DPK,7SC4,1KUZ,1KUP Integrin alpha-IIb ITA2B_HUMAN P08514 B2RCY8 O95366 Q14443 Q17R67 MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT 9E8C,9E8A,9AXL,8ZDG,8ZDF,8XFO,8XFG,8XF6,8XEZ,8XER,8XEN,8XEL,8XEK,8XEI,8GCD,7LA4,8GCE,9DER,9DEQ,9DAX,9DAO,8T2V,8T2U,6MSU,6MSL,3IJE,6AVU,6AVR,6AVQ,4O02,4MMZ,4MMY,4MMX,4G1M,6V4P,6NAJ,6MK0,9E8B,7UKT,7UKP,7UKO,7UK9,7UJK,7UH8,7UFH,7UE0,7UDH,7UDG,7UCY,7UBR,7TCT,7L8P,3ZE2,3ZE1,3ZE0,3ZDZ,3ZDY,3ZDX,3T3P,3T3M,7UJE,7U9V,7U9F,7U60,7TPD,7TMZ,7THO,7TD8,5HDB,4Z7Q,3NIG,3NIF,3NID,4Z7O,4Z7N,8IJ5,3FCU,2VDR,2VDQ,2VDP,2VDO,2VDN,2VDM,2VDL,2VDK,2VC2,1TYE,2KNC,2KV9,1M8O,2LJF,2LJE,2LJD,1S4X,2MTP,2L1C,1KUZ,1KUP Integrin beta-3 ITB3_HUMAN P05106 A0PJW2 D3DXJ8 O15495 Q12806 Q13413 Q14648 Q16499