BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50067115 C=CCn1c2nc[nH]c2c(=O)n(CC=C)c1=O InChI=1S/C11H12N4O2/c1-3-5-14-9-8(12-7-13-9)10(16)15(6-4-2)11(14)17/h3-4,7H,1-2,5-6H2,(H,12,13) NUZFZZOVBJUJQN-UHFFFAOYSA-N 50022725 1,3-Diallyl-3,7-dihydro-purine-2,6-dione::CHEMBL286785 Adenosine receptor A1 Rattus norvegicus 10000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022725 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022725&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 22995178 103933287 CHEMBL286785 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067118 CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1 InChI=1S/C14H14N4O2/c1-2-8-18-13(19)10-12(17-14(18)20)16-11(15-10)9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H,15,16)(H,17,20) LNATVXLECNOWHK-UHFFFAOYSA-N 50018152 CHEMBL274855::8-Phenyl-1-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 67 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018152 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018152&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15627855 103929328 CHEMBL274855 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067119 CCn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCCC1 InChI=1S/C13H18N4O2/c1-2-17-12(18)9-11(16-13(17)19)15-10(14-9)8-6-4-3-5-7-8/h8H,2-7H2,1H3,(H,14,15)(H,16,19) DRTZRNZCONENQR-UHFFFAOYSA-N 50042194 8-Cyclohexyl-1-ethyl-3,7-dihydro-purine-2,6-dione::CHEMBL112587 Adenosine receptor A1 Rattus norvegicus 76 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042194 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042194&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14978320 103973802 CHEMBL112587 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067120 CCCn1cnc2[nH]c(=O)[nH]c(=O)c12 InChI=1S/C8H10N4O2/c1-2-3-12-4-9-6-5(12)7(13)11-8(14)10-6/h4H,2-3H2,1H3,(H2,10,11,13,14) YZYPLLAMOKYMRE-UHFFFAOYSA-N 50042193 7-Propyl-3,7-dihydro-purine-2,6-dione::CHEMBL114892 Adenosine receptor A1 Rattus norvegicus 18000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042193 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042193&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 19008965 103973801 CHEMBL114892 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067122 C=CCn1cnc2n(CC=C)c(=O)[nH]c(=O)c12 InChI=1S/C11H12N4O2/c1-3-5-14-7-12-9-8(14)10(16)13-11(17)15(9)6-4-2/h3-4,7H,1-2,5-6H2,(H,13,16,17) YNBQDPJFVMRANZ-UHFFFAOYSA-N 50042197 3,7-Diallyl-3,7-dihydro-purine-2,6-dione::CHEMBL324125 Adenosine receptor A1 Rattus norvegicus 36000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042197 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042197&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 12318905 103973805 CHEMBL324125 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067123 CCCn1c2nc([nH]c2c(=O)[nH]c1=O)-c1ccccc1 InChI=1S/C14H14N4O2/c1-2-8-18-12-10(13(19)17-14(18)20)15-11(16-12)9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H,15,16)(H,17,19,20) IFTBXZYFIQVMHB-UHFFFAOYSA-N 50018155 CHEMBL20806::8-Phenyl-3-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 9800.0 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018155 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018155&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15627849 103929331 CHEMBL20806 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067124 CCn1c2nc[nH]c2c(=O)n(CC)c1=O InChI=1S/C9H12N4O2/c1-3-12-7-6(10-5-11-7)8(14)13(4-2)9(12)15/h5H,3-4H2,1-2H3,(H,10,11) GIMNFISWKTZFKJ-UHFFFAOYSA-N 82021 NSC_101420::CAS_101420::CHEMBL416013::1,3-Diethylxanthine Adenosine receptor A1 Rattus norvegicus 3700 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82021 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82021&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 101420 131342595 CHEMBL416013 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067125 O=c1[nH]c2nc[nH]c2c(=O)n1C1CCCC1 InChI=1S/C10H12N4O2/c15-9-7-8(12-5-11-7)13-10(16)14(9)6-3-1-2-4-6/h5-6H,1-4H2,(H,11,12)(H,13,16) IBCDFVYWAHQNAA-UHFFFAOYSA-N 50042198 1-Cyclopentyl-3,7-dihydro-purine-2,6-dione::CHEMBL302344 Adenosine receptor A1 Rattus norvegicus 11000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042198 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042198&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10998551 103973806 CHEMBL302344 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067128 O=c1[nH]c2nc([nH]c2c(=O)n1CCc1ccccc1)-c1ccccc1 InChI=1S/C19H16N4O2/c24-18-15-17(21-16(20-15)14-9-5-2-6-10-14)22-19(25)23(18)12-11-13-7-3-1-4-8-13/h1-10H,11-12H2,(H,20,21)(H,22,25) SIVONQXMNJQILX-UHFFFAOYSA-N 50042200 1-Phenethyl-8-phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL112588 Adenosine receptor A1 Rattus norvegicus 190 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042200 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042200&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14978322 103973808 CHEMBL112588 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067130 Cn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1 InChI=1S/C12H10N4O2/c1-16-11(17)8-10(15-12(16)18)14-9(13-8)7-5-3-2-4-6-7/h2-6H,1H3,(H,13,14)(H,15,18) UOOOWRVLSKCKGJ-UHFFFAOYSA-N 50018157 CHEMBL9069::1-Methyl-8-phenyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 260 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018157 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018157&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 323342 103929333 CHEMBL9069 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067131 Cn1c(nc2n(C)c(=O)n(CC#C)c(=O)c12)-c1ccccc1 InChI=1S/C16H14N4O2/c1-4-10-20-15(21)12-14(19(3)16(20)22)17-13(18(12)2)11-8-6-5-7-9-11/h1,5-9H,10H2,2-3H3 ZAZXEMSNSTVIIF-UHFFFAOYSA-N 50042201 3,7-Dimethyl-8-phenyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL115940 Adenosine receptor A1 Rattus norvegicus 6100 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042201 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042201&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14978325 103973809 CHEMBL115940 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067136 CCCCn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C9H12N4O2/c1-2-3-4-13-8(14)6-7(11-5-10-6)12-9(13)15/h5H,2-4H2,1H3,(H,10,11)(H,12,15) HZPVRRDNEDXPAJ-UHFFFAOYSA-N 50001498 CHEMBL68278::1-Butyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 9000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001498&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14969715 103915963 CHEMBL68278 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067137 Cn1c(=O)[nH]c2ncn(CC#C)c2c1=O InChI=1S/C9H8N4O2/c1-3-4-13-5-10-7-6(13)8(14)12(2)9(15)11-7/h1,5H,4H2,2H3,(H,11,15) CKTHOUGRPFWXFH-UHFFFAOYSA-N 50042203 1-Methyl-7-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL115356 Adenosine receptor A1 Rattus norvegicus 9900 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042203 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042203&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10375627 103973811 CHEMBL115356 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067140 CCCn1c2nc([nH]c2c(=O)[nH]c1=O)C1CCCCC1 InChI=1S/C14H20N4O2/c1-2-8-18-12-10(13(19)17-14(18)20)15-11(16-12)9-6-4-3-5-7-9/h9H,2-8H2,1H3,(H,15,16)(H,17,19,20) ZDNILTNYWAZWBW-UHFFFAOYSA-N 50018167 CHEMBL21449::8-Cyclohexyl-3-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 850.0 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018167&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15627851 103929343 CHEMBL21449 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067142 CCCCn1cnc2[nH]c(=O)[nH]c(=O)c12 InChI=1S/C9H12N4O2/c1-2-3-4-13-5-10-7-6(13)8(14)12-9(15)11-7/h5H,2-4H2,1H3,(H2,11,12,14,15) GKPZQTMJNRWTNK-UHFFFAOYSA-N 50042199 7-Butyl-3,7-dihydro-purine-2,6-dione::CHEMBL114891 Adenosine receptor A1 Rattus norvegicus 27000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042199 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042199&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10330675 103973807 CHEMBL114891 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067143 Cn1cnc2[nH]c(=O)[nH]c(=O)c12 InChI=1S/C6H6N4O2/c1-10-2-7-4-3(10)5(11)9-6(12)8-4/h2H,1H3,(H2,8,9,11,12) PFWLFWPASULGAN-UHFFFAOYSA-N 82522 7-Methylxanthine::CAS_552-62-5::CHEMBL321248::7-MethylX Adenosine receptor A1 Rattus norvegicus 33000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82522 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82522&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 68374 136350492 CHEMBL321248 C16353 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067146 CCn1c(=O)n(C)c2nc[nH]c2c1=O InChI=1S/C8H10N4O2/c1-3-12-7(13)5-6(10-4-9-5)11(2)8(12)14/h4H,3H2,1-2H3,(H,9,10) KVSRUALMCYFLEP-UHFFFAOYSA-N 50001514 CHEMBL24107::1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 15000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001514 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001514&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 12905388 103915977 CHEMBL24107 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067148 CC(C)Cn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) APIXJSLKIYYUKG-UHFFFAOYSA-N 15336 1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione::3-Isobutyl-1-methylxanthine::CHEMBL275084::isobutylmethylxanthine::IBMX Adenosine receptor A1 Rattus norvegicus 7000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15336 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15336&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 3758 46515641 CHEMBL275084 C13708 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067152 CC(C)Cn1c2nc[nH]c2c(=O)n(CC(C)C)c1=O InChI=1S/C13H20N4O2/c1-8(2)5-16-11-10(14-7-15-11)12(18)17(13(16)19)6-9(3)4/h7-9H,5-6H2,1-4H3,(H,14,15) IPUAJXHKDUKOCH-UHFFFAOYSA-N 50022731 1,3-Diisobutyl-3,7-dihydro-purine-2,6-dione::CHEMBL26350 Adenosine receptor A1 Rattus norvegicus 4000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022731 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022731&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 3048504 103933293 CHEMBL26350 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067154 Cn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C6H6N4O2/c1-10-5(11)3-4(8-2-7-3)9-6(10)12/h2H,1H3,(H,7,8)(H,9,12) MVOYJPOZRLFTCP-UHFFFAOYSA-N 82020 1-Methyl-3,9-dihydro-purine-2,6-dione(1-methyl xanthine)::CHEMBL1250::NSC_80220::CAS_80220::1-Methylxanthine Adenosine receptor A1 Rattus norvegicus 36000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82020 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82020&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 80220 131342594 CHEMBL1250 C16358 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067155 CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(O)(=O)=O InChI=1S/C14H14N4O5S/c1-2-7-18-13(19)10-12(17-14(18)20)16-11(15-10)8-3-5-9(6-4-8)24(21,22)23/h3-6H,2,7H2,1H3,(H,15,16)(H,17,20)(H,21,22,23) UYDRRQPGDSIMNU-UHFFFAOYSA-N 50042209 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid::4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid::CHEMBL8565 Adenosine receptor A1 Rattus norvegicus 2200 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042209 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042209&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 5311479 103973817 CHEMBL8565 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067158 Cn1cnc2[nH]c(=O)n(C)c(=O)c12 InChI=1S/C7H8N4O2/c1-10-3-8-5-4(10)6(12)11(2)7(13)9-5/h3H,1-2H3,(H,9,13) QUNWUDVFRNGTCO-UHFFFAOYSA-N 50042210 1,7-dimethylxanthine::paraxanthine::CHEMBL1158::1,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 21000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042210 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042210&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 4687 103973818 CHEMBL1158 C13747 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067159 CC(C)CCn1c(=O)n(CC(C)C)c2nc[nH]c2c1=O InChI=1S/C14H22N4O2/c1-9(2)5-6-17-13(19)11-12(16-8-15-11)18(14(17)20)7-10(3)4/h8-10H,5-7H2,1-4H3,(H,15,16) HRWQHFZQHIUCCC-UHFFFAOYSA-N 50018154 CHEMBL20613::3-Isobutyl-1-(3-methyl-butyl)-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 13000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018154 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018154&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 152034 103929330 CHEMBL20613 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067160 O=c1[nH]c2nc([nH]c2c(=O)n1CC#C)C1CCCCC1 InChI=1S/C14H16N4O2/c1-2-8-18-13(19)10-12(17-14(18)20)16-11(15-10)9-6-4-3-5-7-9/h1,9H,3-8H2,(H,15,16)(H,17,20) UEWFINIORGZRKR-UHFFFAOYSA-N 50042213 8-Cyclohexyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL114986 Adenosine receptor A1 Rattus norvegicus 170 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042213 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042213&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10564101 103973821 CHEMBL114986 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067161 Clc1cccc(Cn2c(=O)[nH]c3nc[nH]c3c2=O)c1 InChI=1S/C12H9ClN4O2/c13-8-3-1-2-7(4-8)5-17-11(18)9-10(15-6-14-9)16-12(17)19/h1-4,6H,5H2,(H,14,15)(H,16,19) GTQFFNFCPDJIEU-UHFFFAOYSA-N 50042207 1-(3-Chloro-benzyl)-3,7-dihydro-purine-2,6-dione::CHEMBL113103 Adenosine receptor A1 Rattus norvegicus 4900 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042207 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042207&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10858769 103973815 CHEMBL113103 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067166 Cn1c2nc[nH]c2c(=O)n(CC#C)c1=O InChI=1S/C9H8N4O2/c1-3-4-13-8(14)6-7(11-5-10-6)12(2)9(13)15/h1,5H,4H2,2H3,(H,10,11) HTCXWSNPZFYUKL-UHFFFAOYSA-N 50042208 3-Methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL304455 Adenosine receptor A1 Rattus norvegicus 820.0 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042208 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042208&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14978313 103973816 CHEMBL304455 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067168 CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O InChI=1S/C11H16N4O2/c1-3-5-14-9-8(12-7-13-9)10(16)15(6-4-2)11(14)17/h7H,3-6H2,1-2H3,(H,12,13) MJVIGUCNSRXAFO-UHFFFAOYSA-N 82032 CHEMBL157655::1,3-Dipropyl-3,7-dihydro-purine-2,6-dione::CPX::CAS_169317::NSC_169317::1,3-Dipropylxanthine Adenosine receptor A1 Rattus norvegicus 700 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82032 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82032&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 169317 131342606 CHEMBL157655 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067172 O=c1[nH]c2nc[nH]c2c(=O)n1CCc1ccccc1 InChI=1S/C13H12N4O2/c18-12-10-11(15-8-14-10)16-13(19)17(12)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,14,15)(H,16,19) WZIAGOQSFXTMAJ-UHFFFAOYSA-N 50042215 1-Phenethyl-3,7-dihydro-purine-2,6-dione::CHEMBL67949 Adenosine receptor A1 Rattus norvegicus 12000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042215 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042215&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14969717 103973823 CHEMBL67949 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067173 CCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1 InChI=1S/C13H12N4O2/c1-2-17-12(18)9-11(16-13(17)19)15-10(14-9)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H,14,15)(H,16,19) CLFCOXMMCBVJJB-UHFFFAOYSA-N 50042205 1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL287129 Adenosine receptor A1 Rattus norvegicus 150 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042205 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042205&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 640847 103973813 CHEMBL287129 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067174 Cn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9) ZFXYFBGIUFBOJW-UHFFFAOYSA-N 10847 Theophylline (1,3-dimethylxanthine)::1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dimethyl-7H-purine-2,6-dione::CHEMBL190::Aminophylline::Euphylline::Theophylline::Aminophyllin::Afonilum::Cardophyllin::Theophy-lline Adenosine receptor A1 Rattus norvegicus 14000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10847 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10847&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 2153 46511424 CHEMBL190 DB00277 C07130 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067175 CCCn1c(=O)n(C)c2nc[nH]c2c1=O InChI=1S/C9H12N4O2/c1-3-4-13-8(14)6-7(11-5-10-6)12(2)9(13)15/h5H,3-4H2,1-2H3,(H,10,11) UEGOAAXVUJWIHJ-UHFFFAOYSA-N 50001489 CHEMBL112369::3-Methyl-1-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 5700 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001489 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001489&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 174907 103915954 CHEMBL112369 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067178 C=CCn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C8H8N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h2,4H,1,3H2,(H,9,10)(H,11,14) IPKIKTHDWDXHPU-UHFFFAOYSA-N 50042206 1-Allyl-3,7-dihydro-purine-2,6-dione::CHEMBL66899 Adenosine receptor A1 Rattus norvegicus 9200.0 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042206 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042206&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14969716 103973814 CHEMBL66899 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067181 Clc1cccc(Cn2c(=O)[nH]c3nc([nH]c3c2=O)-c2ccccc2)c1 InChI=1S/C18H13ClN4O2/c19-13-8-4-5-11(9-13)10-23-17(24)14-16(22-18(23)25)21-15(20-14)12-6-2-1-3-7-12/h1-9H,10H2,(H,20,21)(H,22,25) VZVJWXAMSJRLAW-UHFFFAOYSA-N 50042218 1-(3-Chloro-benzyl)-8-phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL325959 Adenosine receptor A1 Rattus norvegicus 68.0 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042218 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042218&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14978321 103973826 CHEMBL325959 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067182 Cn1cnc2[nH]c(=O)n(CC#C)c(=O)c12 InChI=1S/C9H8N4O2/c1-3-4-13-8(14)6-7(11-9(13)15)10-5-12(6)2/h1,5H,4H2,2H3,(H,11,15) JIKBMHWIVSIYNB-UHFFFAOYSA-N 50042219 7-Methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL115556 Adenosine receptor A1 Rattus norvegicus 22000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042219 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042219&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14978315 103973827 CHEMBL115556 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067189 CC(=O)Cn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C13H16N4O3/c1-7(18)6-17-12(19)9-11(16-13(17)20)15-10(14-9)8-4-2-3-5-8/h8H,2-6H2,1H3,(H,14,15)(H,16,20) HHMRMOJSPJAOSO-UHFFFAOYSA-N 50042212 8-Cyclopentyl-1-(2-oxo-propyl)-3,7-dihydro-purine-2,6-dione::CHEMBL113668 Adenosine receptor A1 Rattus norvegicus 2500 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042212 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042212&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14962990 103973820 CHEMBL113668 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067190 O=c1[nH]c2nc([nH]c2c(=O)[nH]1)-c1ccccc1 InChI=1S/C11H8N4O2/c16-10-7-9(14-11(17)15-10)13-8(12-7)6-4-2-1-3-5-6/h1-5H,(H3,12,13,14,15,16,17) ACCCXSZCOGNLFL-UHFFFAOYSA-N 50042214 8-Phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL285191 Adenosine receptor A1 Rattus norvegicus 2500 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042214 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042214&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 12295530 103973822 CHEMBL285191 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067191 CCCn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C8H10N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,14) IWBONKMODGBEOX-UHFFFAOYSA-N 50001490 CHEMBL39986::1-Propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 13000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001490 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001490&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 128525 103915955 CHEMBL39986 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067192 CCCn1c(=O)[nH]c2ncn(C)c2c1=O InChI=1S/C9H12N4O2/c1-3-4-13-8(14)6-7(11-9(13)15)10-5-12(6)2/h5H,3-4H2,1-2H3,(H,11,15) OUAXJUOBOVPHAQ-UHFFFAOYSA-N 50042196 7-Methyl-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL115670 Adenosine receptor A1 Rattus norvegicus 21000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042196 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042196&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14978314 103973804 CHEMBL115670 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067193 O=c1[nH]c2nc[nH]c2c(=O)n1CC#C InChI=1S/C8H6N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h1,4H,3H2,(H,9,10)(H,11,14) HJYAFKKSAAYVHQ-UHFFFAOYSA-N 50042217 1-Prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL67415 Adenosine receptor A1 Rattus norvegicus 20000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042217 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042217&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10219753 103973825 CHEMBL67415 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067194 Cn1c2nc([nH]c2c(=O)n(CC=C)c1=O)-c1ccccc1 InChI=1S/C15H14N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h3-8H,1,9H2,2H3,(H,16,17) MJCQAXMJLOGLCR-UHFFFAOYSA-N 50020960 CHEMBL10873::1-Allyl-3-methyl-8-phenyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 100 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020960 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020960&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10379032 103931675 CHEMBL10873 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067195 Cn1cnc2c1C(=O)NC(=O)N2C InChI=1S/C7H8N4O2/c1-10-3-8-5-4(10)6(12)9-7(13)11(5)2/h3H,1-2H3,(H,9,12,13) YAPQBXQYLJRXSA-UHFFFAOYSA-N 50014260 theobromine::CHEMBL1114::3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione::Theobromin::3,7-dimethylpurine-2,6-dione::3,7-dimethylxanthine::3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 105000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014260 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014260&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 37T 2EFJ,6ICQ,7VRO,7VRQ 5429 103926282 CHEMBL1114 DB01412 C07480 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067198 Cn1c2nc([nH]c2c(=O)[nH]c1=O)-c1ccccc1 InChI=1S/C12H10N4O2/c1-16-10-8(11(17)15-12(16)18)13-9(14-10)7-5-3-2-4-6-7/h2-6H,1H3,(H,13,14)(H,15,17,18) WQKYRUYHWSIGAN-UHFFFAOYSA-N 50042220 3-Methyl-8-phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL115614 Adenosine receptor A1 Rattus norvegicus 3400 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042220 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042220&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 5040241 103973828 CHEMBL115614 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067199 CCCn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C9H12N4O2/c1-3-4-13-7-6(10-5-11-7)8(14)12(2)9(13)15/h5H,3-4H2,1-2H3,(H,10,11) MCPROACZLSAAPY-UHFFFAOYSA-N 50001509 CHEMBL286976::1-Methyl-3-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 6300 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001509 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001509&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 86344 103915972 CHEMBL286976 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067200 O=c1[nH]c2nc([nH]c2c(=O)n1CC#C)-c1ccccc1 InChI=1S/C14H10N4O2/c1-2-8-18-13(19)10-12(17-14(18)20)16-11(15-10)9-6-4-3-5-7-9/h1,3-7H,8H2,(H,15,16)(H,17,20) NBMRBBJMCIDGIV-UHFFFAOYSA-N 50042216 8-Phenyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL114974 Adenosine receptor A1 Rattus norvegicus 210 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042216 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042216&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 640849 103973824 CHEMBL114974 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067202 CCCn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C13H18N4O2/c1-2-7-17-12(18)9-11(16-13(17)19)15-10(14-9)8-5-3-4-6-8/h8H,2-7H2,1H3,(H,14,15)(H,16,19) CUGZRZZLABJZOU-UHFFFAOYSA-N 50042211 8-Cyclopentyl-1-propylX::CHEMBL37243::8-Cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 14 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042211 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042211&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10563436 103973819 CHEMBL37243 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067203 CCCN1c2c([nH]cn2)C(=O)NC1=O InChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14) SIQPXVQCUCHWDI-UHFFFAOYSA-N 50001493 3-Propylxanthine (enprofylline)::3-Propyl-3,7-dihydro-purine-2,6-dione(enprofylline)::CHEMBL279898::3-Propyl-3,7-dihydro-purine-2,6-dione::ENPROFYLLINE Adenosine receptor A1 Rattus norvegicus 32000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001493 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001493&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search A1BD3 9E1D 1676 103915958 CHEMBL279898 DB00824 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067204 CC(C)n1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C9H12N4O2/c1-5(2)13-7-6(10-4-11-7)8(14)12(3)9(13)15/h4-5H,1-3H3,(H,10,11) ZBQTVZYXBOKEMJ-UHFFFAOYSA-N 50025581 3-Isopropyl-1-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL26119 Adenosine receptor A1 Rattus norvegicus 12000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025581 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025581&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10219934 103935453 CHEMBL26119 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50067205 O=c1[nH]c2nc[nH]c2c(=O)n1Cc1ccccc1 InChI=1S/C12H10N4O2/c17-11-9-10(14-7-13-9)15-12(18)16(11)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,13,14)(H,15,18) PCBFNMPKPKBIAA-UHFFFAOYSA-N 50042204 1-Benzyl-3,7-dihydro-purine-2,6-dione::CHEMBL113155 Adenosine receptor A1 Rattus norvegicus 2800 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042204 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042204&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 6425731 103973812 CHEMBL113155 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50673452 O=c1[nH]c2nc([nH]c2c(=O)n1CC#C)C1CCCCC1 InChI=1S/C14H16N4O2/c1-2-8-18-13(19)10-12(17-14(18)20)16-11(15-10)9-6-4-3-5-7-9/h1,9H,3-8H2,(H,15,16)(H,17,20) UEWFINIORGZRKR-UHFFFAOYSA-N 50042213 8-Cyclohexyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL114986 Adenosine receptor A2a/A2b Rattus norvegicus 1700 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042213 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042213&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10564101 103973821 CHEMBL114986 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673453 CCn1c(=O)n(C)c2nc[nH]c2c1=O InChI=1S/C8H10N4O2/c1-3-12-7(13)5-6(10-4-9-5)11(2)8(12)14/h4H,3H2,1-2H3,(H,9,10) KVSRUALMCYFLEP-UHFFFAOYSA-N 50001514 CHEMBL24107::1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 23000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001514 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001514&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 12905388 103915977 CHEMBL24107 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673454 CCCCn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C9H12N4O2/c1-2-3-4-13-8(14)6-7(11-5-10-6)12-9(13)15/h5H,2-4H2,1H3,(H,10,11)(H,12,15) HZPVRRDNEDXPAJ-UHFFFAOYSA-N 50001498 CHEMBL68278::1-Butyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 61000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001498&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14969715 103915963 CHEMBL68278 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673455 Cn1cnc2[nH]c(=O)[nH]c(=O)c12 InChI=1S/C6H6N4O2/c1-10-2-7-4-3(10)5(11)9-6(12)8-4/h2H,1H3,(H2,8,9,11,12) PFWLFWPASULGAN-UHFFFAOYSA-N 82522 7-Methylxanthine::CAS_552-62-5::CHEMBL321248::7-MethylX Adenosine receptor A2a/A2b Rattus norvegicus 59000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82522 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82522&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 68374 136350492 CHEMBL321248 C16353 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673456 Cn1cnc2[nH]c(=O)n(C)c(=O)c12 InChI=1S/C7H8N4O2/c1-10-3-8-5-4(10)6(12)11(2)7(13)9-5/h3H,1-2H3,(H,9,13) QUNWUDVFRNGTCO-UHFFFAOYSA-N 50042210 1,7-dimethylxanthine::paraxanthine::CHEMBL1158::1,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 32000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042210 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042210&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 4687 103973818 CHEMBL1158 C13747 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673457 CCCn1c(=O)n(C)c2nc[nH]c2c1=O InChI=1S/C9H12N4O2/c1-3-4-13-8(14)6-7(11-5-10-6)12(2)9(13)15/h5H,3-4H2,1-2H3,(H,10,11) UEGOAAXVUJWIHJ-UHFFFAOYSA-N 50001489 CHEMBL112369::3-Methyl-1-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 37000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001489 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001489&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 174907 103915954 CHEMBL112369 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673458 Cn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C6H6N4O2/c1-10-5(11)3-4(8-2-7-3)9-6(10)12/h2H,1H3,(H,7,8)(H,9,12) MVOYJPOZRLFTCP-UHFFFAOYSA-N 82020 1-Methyl-3,9-dihydro-purine-2,6-dione(1-methyl xanthine)::CHEMBL1250::NSC_80220::CAS_80220::1-Methylxanthine Adenosine receptor A2a/A2b Rattus norvegicus 47000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82020 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82020&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 80220 131342594 CHEMBL1250 C16358 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673459 Clc1cccc(Cn2c(=O)[nH]c3nc[nH]c3c2=O)c1 InChI=1S/C12H9ClN4O2/c13-8-3-1-2-7(4-8)5-17-11(18)9-10(15-6-14-9)16-12(17)19/h1-4,6H,5H2,(H,14,15)(H,16,19) GTQFFNFCPDJIEU-UHFFFAOYSA-N 50042207 1-(3-Chloro-benzyl)-3,7-dihydro-purine-2,6-dione::CHEMBL113103 Adenosine receptor A2a/A2b Rattus norvegicus 26000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042207 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042207&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10858769 103973815 CHEMBL113103 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673461 O=c1[nH]c2nc[nH]c2c(=O)n1Cc1ccccc1 InChI=1S/C12H10N4O2/c17-11-9-10(14-7-13-9)15-12(18)16(11)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,13,14)(H,15,18) PCBFNMPKPKBIAA-UHFFFAOYSA-N 50042204 1-Benzyl-3,7-dihydro-purine-2,6-dione::CHEMBL113155 Adenosine receptor A2a/A2b Rattus norvegicus 22000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042204 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042204&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 6425731 103973812 CHEMBL113155 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673462 CCCn1c2nc([nH]c2c(=O)[nH]c1=O)-c1ccccc1 InChI=1S/C14H14N4O2/c1-2-8-18-12-10(13(19)17-14(18)20)15-11(16-12)9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H,15,16)(H,17,19,20) IFTBXZYFIQVMHB-UHFFFAOYSA-N 50018155 CHEMBL20806::8-Phenyl-3-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 61000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018155 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018155&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15627849 103929331 CHEMBL20806 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673463 C=CCn1cnc2n(CC=C)c(=O)[nH]c(=O)c12 InChI=1S/C11H12N4O2/c1-3-5-14-7-12-9-8(14)10(16)13-11(17)15(9)6-4-2/h3-4,7H,1-2,5-6H2,(H,13,16,17) YNBQDPJFVMRANZ-UHFFFAOYSA-N 50042197 3,7-Diallyl-3,7-dihydro-purine-2,6-dione::CHEMBL324125 Adenosine receptor A2a/A2b Rattus norvegicus 36000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042197 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042197&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 12318905 103973805 CHEMBL324125 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673464 CN1c2c([nH]cn2)C(=O)NC1=O InChI=1S/C6H6N4O2/c1-10-4-3(7-2-8-4)5(11)9-6(10)12/h2H,1H3,(H,7,8)(H,9,11,12) GMSNIKWWOQHZGF-UHFFFAOYSA-N 50001515 CHEMBL619::3-Methyl-3,7-dihydro-purine-2,6-dione::3-Methyl-3,9-dihydro-purine-2,6-dione(3-methyl xanthine)::1-Methylxanthine (1-Mx) Adenosine receptor A2a/A2b Rattus norvegicus 59000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001515 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001515&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search I7U 8K0V 70639 103915978 CHEMBL619 C16357 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673465 CC(C)Cn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) APIXJSLKIYYUKG-UHFFFAOYSA-N 15336 1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione::3-Isobutyl-1-methylxanthine::CHEMBL275084::isobutylmethylxanthine::IBMX Adenosine receptor A2a/A2b Rattus norvegicus 16000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15336 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15336&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 3758 46515641 CHEMBL275084 C13708 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673466 CCCN1c2c([nH]cn2)C(=O)NC1=O InChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14) SIQPXVQCUCHWDI-UHFFFAOYSA-N 50001493 3-Propylxanthine (enprofylline)::3-Propyl-3,7-dihydro-purine-2,6-dione(enprofylline)::CHEMBL279898::3-Propyl-3,7-dihydro-purine-2,6-dione::ENPROFYLLINE Adenosine receptor A2a/A2b Rattus norvegicus 137000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001493 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001493&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search A1BD3 9E1D 1676 103915958 CHEMBL279898 DB00824 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673467 O=c1[nH]c2nc([nH]c2c(=O)[nH]1)-c1ccccc1 InChI=1S/C11H8N4O2/c16-10-7-9(14-11(17)15-10)13-8(12-7)6-4-2-1-3-5-6/h1-5H,(H3,12,13,14,15,16,17) ACCCXSZCOGNLFL-UHFFFAOYSA-N 50042214 8-Phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL285191 Adenosine receptor A2a/A2b Rattus norvegicus 21000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042214 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042214&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 12295530 103973822 CHEMBL285191 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673468 CC(C)CCn1c(=O)n(CC(C)C)c2nc[nH]c2c1=O InChI=1S/C14H22N4O2/c1-9(2)5-6-17-13(19)11-12(16-8-15-11)18(14(17)20)7-10(3)4/h8-10H,5-7H2,1-4H3,(H,15,16) HRWQHFZQHIUCCC-UHFFFAOYSA-N 50018154 CHEMBL20613::3-Isobutyl-1-(3-methyl-butyl)-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 11000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018154 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018154&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 152034 103929330 CHEMBL20613 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673469 Cn1c(=O)[nH]c2ncn(CC#C)c2c1=O InChI=1S/C9H8N4O2/c1-3-4-13-5-10-7-6(13)8(14)12(2)9(15)11-7/h1,5H,4H2,2H3,(H,11,15) CKTHOUGRPFWXFH-UHFFFAOYSA-N 50042203 1-Methyl-7-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL115356 Adenosine receptor A2a/A2b Rattus norvegicus 14000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042203 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042203&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10375627 103973811 CHEMBL115356 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673470 CCCCn1cnc2[nH]c(=O)[nH]c(=O)c12 InChI=1S/C9H12N4O2/c1-2-3-4-13-5-10-7-6(13)8(14)12-9(15)11-7/h5H,2-4H2,1H3,(H2,11,12,14,15) GKPZQTMJNRWTNK-UHFFFAOYSA-N 50042199 7-Butyl-3,7-dihydro-purine-2,6-dione::CHEMBL114891 Adenosine receptor A2a/A2b Rattus norvegicus 66000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042199 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042199&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10330675 103973807 CHEMBL114891 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673472 CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O InChI=1S/C11H16N4O2/c1-3-5-14-9-8(12-7-13-9)10(16)15(6-4-2)11(14)17/h7H,3-6H2,1-2H3,(H,12,13) MJVIGUCNSRXAFO-UHFFFAOYSA-N 82032 CHEMBL157655::1,3-Dipropyl-3,7-dihydro-purine-2,6-dione::CPX::CAS_169317::NSC_169317::1,3-Dipropylxanthine Adenosine receptor A2a/A2b Rattus norvegicus 6600 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82032 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82032&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 169317 131342606 CHEMBL157655 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673473 CCCn1c(=O)[nH]c2ncn(C)c2c1=O InChI=1S/C9H12N4O2/c1-3-4-13-8(14)6-7(11-9(13)15)10-5-12(6)2/h5H,3-4H2,1-2H3,(H,11,15) OUAXJUOBOVPHAQ-UHFFFAOYSA-N 50042196 7-Methyl-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL115670 Adenosine receptor A2a/A2b Rattus norvegicus 29000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042196 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042196&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14978314 103973804 CHEMBL115670 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673474 C=CCn1c2nc[nH]c2c(=O)n(CC=C)c1=O InChI=1S/C11H12N4O2/c1-3-5-14-9-8(12-7-13-9)10(16)15(6-4-2)11(14)17/h3-4,7H,1-2,5-6H2,(H,12,13) NUZFZZOVBJUJQN-UHFFFAOYSA-N 50022725 1,3-Diallyl-3,7-dihydro-purine-2,6-dione::CHEMBL286785 Adenosine receptor A2a/A2b Rattus norvegicus 20000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022725 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022725&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 22995178 103933287 CHEMBL286785 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673475 O=c1[nH]c2nc([nH]c2c(=O)n1CC#C)-c1ccccc1 InChI=1S/C14H10N4O2/c1-2-8-18-13(19)10-12(17-14(18)20)16-11(15-10)9-6-4-3-5-7-9/h1,3-7H,8H2,(H,15,16)(H,17,20) NBMRBBJMCIDGIV-UHFFFAOYSA-N 50042216 8-Phenyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL114974 Adenosine receptor A2a/A2b Rattus norvegicus 730 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042216 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042216&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 640849 103973824 CHEMBL114974 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673476 Cn1cnc2[nH]c(=O)n(CC#C)c(=O)c12 InChI=1S/C9H8N4O2/c1-3-4-13-8(14)6-7(11-9(13)15)10-5-12(6)2/h1,5H,4H2,2H3,(H,11,15) JIKBMHWIVSIYNB-UHFFFAOYSA-N 50042219 7-Methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL115556 Adenosine receptor A2a/A2b Rattus norvegicus 16000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042219 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042219&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14978315 103973827 CHEMBL115556 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673477 CC(C)n1c2nc[nH]c2c(=O)[nH]c1=O InChI=1S/C8H10N4O2/c1-4(2)12-6-5(9-3-10-6)7(13)11-8(12)14/h3-4H,1-2H3,(H,9,10)(H,11,13,14) RTXYVOHVEZKIAC-UHFFFAOYSA-N 50231340 CHEMBL112295 Adenosine receptor A2a/A2b Rattus norvegicus 53000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231340 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231340&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15423159 381616928 CHEMBL112295 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673478 CCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1 InChI=1S/C13H12N4O2/c1-2-17-12(18)9-11(16-13(17)19)15-10(14-9)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H,14,15)(H,16,19) CLFCOXMMCBVJJB-UHFFFAOYSA-N 50042205 1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL287129 Adenosine receptor A2a/A2b Rattus norvegicus 1800 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042205 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042205&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 640847 103973813 CHEMBL287129 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673488 C=CCn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C8H8N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h2,4H,1,3H2,(H,9,10)(H,11,14) IPKIKTHDWDXHPU-UHFFFAOYSA-N 50042206 1-Allyl-3,7-dihydro-purine-2,6-dione::CHEMBL66899 Adenosine receptor A2a/A2b Rattus norvegicus 10000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042206 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042206&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14969716 103973814 CHEMBL66899 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673493 O=c1[nH]c2nc[nH]c2c(=O)n1CC#C InChI=1S/C8H6N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h1,4H,3H2,(H,9,10)(H,11,14) HJYAFKKSAAYVHQ-UHFFFAOYSA-N 50042217 1-Prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL67415 Adenosine receptor A2a/A2b Rattus norvegicus 26000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042217 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042217&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10219753 103973825 CHEMBL67415 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673496 CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1 InChI=1S/C14H14N4O2/c1-2-8-18-13(19)10-12(17-14(18)20)16-11(15-10)9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H,15,16)(H,17,20) LNATVXLECNOWHK-UHFFFAOYSA-N 50018152 CHEMBL274855::8-Phenyl-1-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 1900 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018152 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018152&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15627855 103929328 CHEMBL274855 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673500 CC(=O)Cn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C13H16N4O3/c1-7(18)6-17-12(19)9-11(16-13(17)20)15-10(14-9)8-4-2-3-5-8/h8H,2-6H2,1H3,(H,14,15)(H,16,20) HHMRMOJSPJAOSO-UHFFFAOYSA-N 50042212 8-Cyclopentyl-1-(2-oxo-propyl)-3,7-dihydro-purine-2,6-dione::CHEMBL113668 Adenosine receptor A2a/A2b Rattus norvegicus 9700 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042212 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042212&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14962990 103973820 CHEMBL113668 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673501 Cn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1 InChI=1S/C12H10N4O2/c1-16-11(17)8-10(15-12(16)18)14-9(13-8)7-5-3-2-4-6-7/h2-6H,1H3,(H,13,14)(H,15,18) UOOOWRVLSKCKGJ-UHFFFAOYSA-N 50018157 CHEMBL9069::1-Methyl-8-phenyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 2200 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018157 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018157&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 323342 103929333 CHEMBL9069 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673511 CCn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCCC1 InChI=1S/C13H18N4O2/c1-2-17-12(18)9-11(16-13(17)19)15-10(14-9)8-6-4-3-5-7-8/h8H,2-7H2,1H3,(H,14,15)(H,16,19) DRTZRNZCONENQR-UHFFFAOYSA-N 50042194 8-Cyclohexyl-1-ethyl-3,7-dihydro-purine-2,6-dione::CHEMBL112587 Adenosine receptor A2a/A2b Rattus norvegicus 2300 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042194 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042194&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14978320 103973802 CHEMBL112587 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673515 CCCn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C9H12N4O2/c1-3-4-13-7-6(10-5-11-7)8(14)12(2)9(13)15/h5H,3-4H2,1-2H3,(H,10,11) MCPROACZLSAAPY-UHFFFAOYSA-N 50001509 CHEMBL286976::1-Methyl-3-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 19000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001509 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001509&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 86344 103915972 CHEMBL286976 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673516 Cn1c2nc([nH]c2c(=O)n(CC=C)c1=O)-c1ccccc1 InChI=1S/C15H14N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h3-8H,1,9H2,2H3,(H,16,17) MJCQAXMJLOGLCR-UHFFFAOYSA-N 50020960 CHEMBL10873::1-Allyl-3-methyl-8-phenyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 2100 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020960 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020960&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10379032 103931675 CHEMBL10873 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673538 O=c1[nH]c2nc[nH]c2c(=O)n1C1CCCC1 InChI=1S/C10H12N4O2/c15-9-7-8(12-5-11-7)13-10(16)14(9)6-3-1-2-4-6/h5-6H,1-4H2,(H,11,12)(H,13,16) IBCDFVYWAHQNAA-UHFFFAOYSA-N 50042198 1-Cyclopentyl-3,7-dihydro-purine-2,6-dione::CHEMBL302344 Adenosine receptor A2a/A2b Rattus norvegicus 13000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042198 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042198&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10998551 103973806 CHEMBL302344 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673543 Cn1c(nc2n(C)c(=O)n(CC#C)c(=O)c12)-c1ccccc1 InChI=1S/C16H14N4O2/c1-4-10-20-15(21)12-14(19(3)16(20)22)17-13(18(12)2)11-8-6-5-7-9-11/h1,5-9H,10H2,2-3H3 ZAZXEMSNSTVIIF-UHFFFAOYSA-N 50042201 3,7-Dimethyl-8-phenyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL115940 Adenosine receptor A2a/A2b Rattus norvegicus 6400 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042201 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042201&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14978325 103973809 CHEMBL115940 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673547 CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(cc1)S(O)(=O)=O InChI=1S/C14H14N4O5S/c1-2-7-18-13(19)10-12(17-14(18)20)16-11(15-10)8-3-5-9(6-4-8)24(21,22)23/h3-6H,2,7H2,1H3,(H,15,16)(H,17,20)(H,21,22,23) UYDRRQPGDSIMNU-UHFFFAOYSA-N 50042209 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid::4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid::CHEMBL8565 Adenosine receptor A2a/A2b Rattus norvegicus 24000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042209 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042209&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 5311479 103973817 CHEMBL8565 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673552 Cn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9) ZFXYFBGIUFBOJW-UHFFFAOYSA-N 10847 Theophylline (1,3-dimethylxanthine)::1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dimethyl-7H-purine-2,6-dione::CHEMBL190::Aminophylline::Euphylline::Theophylline::Aminophyllin::Afonilum::Cardophyllin::Theophy-lline Adenosine receptor A2a/A2b Rattus norvegicus 22000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10847 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10847&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 2153 46511424 CHEMBL190 DB00277 C07130 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673592 CCn1c2nc[nH]c2c(=O)n(CC)c1=O InChI=1S/C9H12N4O2/c1-3-12-7-6(10-5-11-7)8(14)13(4-2)9(12)15/h5H,3-4H2,1-2H3,(H,10,11) GIMNFISWKTZFKJ-UHFFFAOYSA-N 82021 NSC_101420::CAS_101420::CHEMBL416013::1,3-Diethylxanthine Adenosine receptor A2a/A2b Rattus norvegicus 31000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82021 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82021&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 101420 131342595 CHEMBL416013 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673598 CC(C)Cn1c2nc[nH]c2c(=O)n(CC(C)C)c1=O InChI=1S/C13H20N4O2/c1-8(2)5-16-11-10(14-7-15-11)12(18)17(13(16)19)6-9(3)4/h7-9H,5-6H2,1-4H3,(H,14,15) IPUAJXHKDUKOCH-UHFFFAOYSA-N 50022731 1,3-Diisobutyl-3,7-dihydro-purine-2,6-dione::CHEMBL26350 Adenosine receptor A2a/A2b Rattus norvegicus 15000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022731 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022731&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 3048504 103933293 CHEMBL26350 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673604 Cn1c2nc[nH]c2c(=O)n(CC#C)c1=O InChI=1S/C9H8N4O2/c1-3-4-13-8(14)6-7(11-5-10-6)12(2)9(13)15/h1,5H,4H2,2H3,(H,10,11) HTCXWSNPZFYUKL-UHFFFAOYSA-N 50042208 3-Methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione::CHEMBL304455 Adenosine receptor A2a/A2b Rattus norvegicus 4800 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042208 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042208&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14978313 103973816 CHEMBL304455 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673614 CC(C)n1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C9H12N4O2/c1-5(2)13-7-6(10-4-11-7)8(14)12(3)9(13)15/h4-5H,1-3H3,(H,10,11) ZBQTVZYXBOKEMJ-UHFFFAOYSA-N 50025581 3-Isopropyl-1-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL26119 Adenosine receptor A2a/A2b Rattus norvegicus 16000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025581 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025581&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10219934 103935453 CHEMBL26119 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673615 CCCn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C13H18N4O2/c1-2-7-17-12(18)9-11(16-13(17)19)15-10(14-9)8-5-3-4-6-8/h8H,2-7H2,1H3,(H,14,15)(H,16,19) CUGZRZZLABJZOU-UHFFFAOYSA-N 50042211 8-Cyclopentyl-1-propylX::CHEMBL37243::8-Cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 580 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042211 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042211&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10563436 103973819 CHEMBL37243 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673616 CCCn1c2nc([nH]c2c(=O)[nH]c1=O)C1CCCCC1 InChI=1S/C14H20N4O2/c1-2-8-18-12-10(13(19)17-14(18)20)15-11(16-12)9-6-4-3-5-7-9/h9H,2-8H2,1H3,(H,15,16)(H,17,19,20) ZDNILTNYWAZWBW-UHFFFAOYSA-N 50018167 CHEMBL21449::8-Cyclohexyl-3-propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 24000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018167 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018167&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15627851 103929343 CHEMBL21449 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50673617 CCCn1c(=O)[nH]c2nc[nH]c2c1=O InChI=1S/C8H10N4O2/c1-2-3-12-7(13)5-6(10-4-9-5)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,14) IWBONKMODGBEOX-UHFFFAOYSA-N 50001490 CHEMBL39986::1-Propyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 33000 ChEMBL 10.1021/jm00074a015 10.7270/Q26Q1W9W 8230124 Muller, CE; Shi, D; Manning, M; Daly, JW 12/10/1993 11/10/2009 Pharmazeutische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001490 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001490&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 128525 103915955 CHEMBL39986 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276