BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50067206 CCCCC1=NC2(CCCCCCCCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C31H40N2O3/c1-2-3-16-28-32-31(21-12-8-6-4-5-7-9-13-22-31)30(36)33(28)23-24-17-19-25(20-18-24)26-14-10-11-15-27(26)29(34)35/h10-11,14-15,17-20H,2-9,12-13,16,21-23H2,1H3,(H,34,35) WOECBIVPSJRGFG-UHFFFAOYSA-N 50042221 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.10]pentadec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL324245 Type-1 angiotensin II receptor B Rattus norvegicus 350 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042221 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042221&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342045 103973829 CHEMBL324245 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067207 CCCCC1=NC(CCCC)(CCCC)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C29H38N2O3/c1-4-7-14-26-30-29(19-8-5-2,20-9-6-3)28(34)31(26)21-22-15-17-23(18-16-22)24-12-10-11-13-25(24)27(32)33/h10-13,15-18H,4-9,14,19-21H2,1-3H3,(H,32,33) LDBGBLYCWFBLDN-UHFFFAOYSA-N 50042222 4'-(2,4,4-Tributyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL46782 Type-1 angiotensin II receptor B Rattus norvegicus 1700 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042222 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042222&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44291830 103973830 CHEMBL46782 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067208 CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn(C)n1 |t:4| InChI=1S/C26H30N6O/c1-3-4-11-23-27-26(16-7-8-17-26)25(33)32(23)18-19-12-14-20(15-13-19)21-9-5-6-10-22(21)24-28-30-31(2)29-24/h5-6,9-10,12-15H,3-4,7-8,11,16-18H2,1-2H3 PRGCYHZKGCRFQQ-UHFFFAOYSA-N 50042223 2-Butyl-3-[2'-(2-methyl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one::CHEMBL410724 Type-1 angiotensin II receptor B Rattus norvegicus 660 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042223 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042223&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341698 103973831 CHEMBL410724 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067209 CCCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:5| InChI=1S/C26H30N2O3/c1-2-3-4-11-23-27-26(16-7-8-17-26)25(31)28(23)18-19-12-14-20(15-13-19)21-9-5-6-10-22(21)24(29)30/h5-6,9-10,12-15H,2-4,7-8,11,16-18H2,1H3,(H,29,30) NODORMDBKPDUBB-UHFFFAOYSA-N 50042225 4'-(4-Oxo-2-pentyl-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114267 Type-1 angiotensin II receptor B Rattus norvegicus 24 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042225 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042225&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341794 103973833 CHEMBL114267 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067210 CCCCC1=NC2(CCN(CC2)C(=O)C(N)CCCNC(N)=N)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C31H41N7O4/c1-2-3-10-26-36-31(15-18-37(19-16-31)27(39)25(32)9-6-17-35-30(33)34)29(42)38(26)20-21-11-13-22(14-12-21)23-7-4-5-8-24(23)28(40)41/h4-5,7-8,11-14,25H,2-3,6,9-10,15-20,32H2,1H3,(H,40,41)(H4,33,34,35) ZRTZOFLISQZDAV-UHFFFAOYSA-N 50042224 4'-[8-(2-Amino-5-guanidino-pentanoyl)-2-butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL110974 Type-1 angiotensin II receptor B Rattus norvegicus 220 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042224 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042224&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341489 103973832 CHEMBL110974 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067211 CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(=O)OC(C)(C)C |t:4| InChI=1S/C29H36N2O3/c1-5-6-13-25-30-29(18-9-10-19-29)27(33)31(25)20-21-14-16-22(17-15-21)23-11-7-8-12-24(23)26(32)34-28(2,3)4/h7-8,11-12,14-17H,5-6,9-10,13,18-20H2,1-4H3 VPOTWSUIDKEOHK-UHFFFAOYSA-N 50042226 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid tert-butyl ester::4'-(2-butyl-4-oxo-1,3-diazaspiro[4,4]-non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid tertbutyl ester::CHEMBL115835 Type-1 angiotensin II receptor B Rattus norvegicus 3200 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042226 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042226&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 15745369 103973834 CHEMBL115835 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067212 CCCCC1=NC(=O)C2(CCCC2)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C25H28N2O3/c1-2-3-10-22-26-24(30)25(15-6-7-16-25)27(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23(28)29/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,28,29) PHWMNRPJGUQVGL-UHFFFAOYSA-N 50042227 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-2-en-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL113701 Type-1 angiotensin II receptor B Rattus norvegicus 1800 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042227 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042227&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341801 103973835 CHEMBL113701 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067213 CCCCC1=NC2(CCN(CC2)C(=O)C(F)(F)F)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C27H28F3N3O4/c1-2-3-8-22-31-26(13-15-32(16-14-26)25(37)27(28,29)30)24(36)33(22)17-18-9-11-19(12-10-18)20-6-4-5-7-21(20)23(34)35/h4-7,9-12H,2-3,8,13-17H2,1H3,(H,34,35) BBTJOYSQCCPFSK-UHFFFAOYSA-N 50042231 4'-[2-Butyl-4-oxo-8-(2,2,2-trifluoro-acetyl)-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL113330 Type-1 angiotensin II receptor B Rattus norvegicus 140 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042231 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042231&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341713 103973839 CHEMBL113330 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067214 CCCCC1=NC2(Cc3ccccc3C2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C29H28N2O3/c1-2-3-12-26-30-29(17-22-8-4-5-9-23(22)18-29)28(34)31(26)19-20-13-15-21(16-14-20)24-10-6-7-11-25(24)27(32)33/h4-11,13-16H,2-3,12,17-19H2,1H3,(H,32,33) YIXCSIBUXLSBBA-UHFFFAOYSA-N 50042232 2-{4-[2-butyl-5-oxospiro[4,5-dihydro-1H-imidazole-4,2'-(2',3'-dihydro-1'H-indene)]-1-ylmethyl]phenyl}benzoic acid::CHEMBL114983 Type-1 angiotensin II receptor B Rattus norvegicus 60 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042232 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042232&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341824 103973840 CHEMBL114983 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067215 OC(=O)c1ccccc1-c1ccc(CN2C(Cc3ccccc3)=NC3(CCCC3)C2=O)cc1 |c:24| InChI=1S/C28H26N2O3/c31-26(32)24-11-5-4-10-23(24)22-14-12-21(13-15-22)19-30-25(18-20-8-2-1-3-9-20)29-28(27(30)33)16-6-7-17-28/h1-5,8-15H,6-7,16-19H2,(H,31,32) AKPSJDJJPBXDJU-UHFFFAOYSA-N 50042236 4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL115771 Type-1 angiotensin II receptor B Rattus norvegicus 2500 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042236 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042236&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341785 103973844 CHEMBL115771 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067216 CCCCC1=NC2(CCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C24H26N2O3/c1-2-3-9-21-25-24(14-6-15-24)23(29)26(21)16-17-10-12-18(13-11-17)19-7-4-5-8-20(19)22(27)28/h4-5,7-8,10-13H,2-3,6,9,14-16H2,1H3,(H,27,28) FNLKLBNPUDPIHU-UHFFFAOYSA-N 50042238 4'-(6-Butyl-8-oxo-5,7-diaza-spiro[3.4]oct-5-en-7-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL113674 Type-1 angiotensin II receptor B Rattus norvegicus 38 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042238 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042238&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342047 103973846 CHEMBL113674 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067217 CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C#N |t:4| InChI=1S/C25H27N3O/c1-2-3-10-23-27-25(15-6-7-16-25)24(29)28(23)18-19-11-13-20(14-12-19)22-9-5-4-8-21(22)17-26/h4-5,8-9,11-14H,2-3,6-7,10,15-16,18H2,1H3 KWEQEHOPDHARIA-UHFFFAOYSA-N 50042242 4'-(2-butyl-4-oxo-1,3-diaza-spiro[4,4]-non-1-en-3-ylmethyl)-biphe-nyl-2-carbonitrile::4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carbonitrile::CHEMBL332051 Type-1 angiotensin II receptor B Rattus norvegicus 440 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042242 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042242&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 9843116 103973850 CHEMBL332051 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067218 CCCCC1=NC(CC)(CC)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C25H30N2O3/c1-4-7-12-22-26-25(5-2,6-3)24(30)27(22)17-18-13-15-19(16-14-18)20-10-8-9-11-21(20)23(28)29/h8-11,13-16H,4-7,12,17H2,1-3H3,(H,28,29) LCPYFBSBBAXCRH-UHFFFAOYSA-N 50042240 4'-(2-Butyl-4,4-diethyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL296883 Type-1 angiotensin II receptor B Rattus norvegicus 56 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042240 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042240&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44291477 103973848 CHEMBL296883 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067219 CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) JGABCUJSSAEYFF-UHFFFAOYSA-N 50009714 CHEMBL191::{2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-3H-imidazol-4-yl}-methanol(DuP 753) Type-1 angiotensin II receptor B Rattus norvegicus 14 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009714 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009714&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44330456 103922696 CHEMBL191 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067220 CCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:3| InChI=1S/C24H26N2O3/c1-2-7-21-25-24(14-5-6-15-24)23(29)26(21)16-17-10-12-18(13-11-17)19-8-3-4-9-20(19)22(27)28/h3-4,8-13H,2,5-7,14-16H2,1H3,(H,27,28) OMZZLVARBWAOMW-UHFFFAOYSA-N 50042249 4'-(4-Oxo-2-propyl-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL419583 Type-1 angiotensin II receptor B Rattus norvegicus 27 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042249 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042249&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341796 103973857 CHEMBL419583 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067221 CCCCC1=NC2(CCCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C26H30N2O3/c1-2-3-11-23-27-26(16-7-4-8-17-26)25(31)28(23)18-19-12-14-20(15-13-19)21-9-5-6-10-22(21)24(29)30/h5-6,9-10,12-15H,2-4,7-8,11,16-18H2,1H3,(H,29,30) MFRBWXHTGUQKIS-UHFFFAOYSA-N 50042251 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL116170 Type-1 angiotensin II receptor B Rattus norvegicus 7.2 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042251 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042251&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342039 103973859 CHEMBL116170 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067222 OC(=O)c1ccccc1-c1ccc(CN2C(=NC3(CCCC3)C2=O)C2CCCC2)cc1 |c:16| InChI=1S/C26H28N2O3/c29-24(30)22-10-4-3-9-21(22)19-13-11-18(12-14-19)17-28-23(20-7-1-2-8-20)27-26(25(28)31)15-5-6-16-26/h3-4,9-14,20H,1-2,5-8,15-17H2,(H,29,30) VAJMYAASYVMFBN-UHFFFAOYSA-N 50042246 4'-(2-Cyclopentyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL323244 Type-1 angiotensin II receptor B Rattus norvegicus 410 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042246 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042246&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341787 103973854 CHEMBL323244 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067223 CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(=O)OC |t:4| InChI=1S/C26H30N2O3/c1-3-4-11-23-27-26(16-7-8-17-26)25(30)28(23)18-19-12-14-20(15-13-19)21-9-5-6-10-22(21)24(29)31-2/h5-6,9-10,12-15H,3-4,7-8,11,16-18H2,1-2H3 XYYYFJUWDFFJAL-UHFFFAOYSA-N 50042247 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid methyl ester::4'-(2-butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-ylmethyl)-biphe-nyl-2-carboxylic acid methyl ester::CHEMBL325502 Type-1 angiotensin II receptor B Rattus norvegicus 1800 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042247 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042247&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341772 103973855 CHEMBL325502 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067224 CCCCC1NC(=O)C2(CCCC2)N1Cc1ccc(cc1)-c1ccccc1C(O)=O InChI=1S/C25H30N2O3/c1-2-3-10-22-26-24(30)25(15-6-7-16-25)27(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23(28)29/h4-5,8-9,11-14,22H,2-3,6-7,10,15-17H2,1H3,(H,26,30)(H,28,29) ILERVMNMFVURPH-UHFFFAOYSA-N 50042250 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL444060 Type-1 angiotensin II receptor B Rattus norvegicus 3300 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042250 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042250&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341650 103973858 CHEMBL444060 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067225 OC(=O)c1ccccc1-c1ccc(CN2C(=O)C3(CCCC3)N=C2C(F)(F)C(F)(F)C(F)(F)F)cc1 |c:24| InChI=1S/C24H19F7N2O3/c25-22(26,23(27,28)24(29,30)31)19-32-21(11-3-4-12-21)20(36)33(19)13-14-7-9-15(10-8-14)16-5-1-2-6-17(16)18(34)35/h1-2,5-10H,3-4,11-13H2,(H,34,35) YGDOQMAVWCXZMF-UHFFFAOYSA-N 50042252 4'-(2-Heptafluoropropyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114625 Type-1 angiotensin II receptor B Rattus norvegicus 10000 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042252 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042252&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341795 103973860 CHEMBL114625 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067226 CC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:1| InChI=1S/C22H22N2O3/c1-15-23-22(12-4-5-13-22)21(27)24(15)14-16-8-10-17(11-9-16)18-6-2-3-7-19(18)20(25)26/h2-3,6-11H,4-5,12-14H2,1H3,(H,25,26) QOBDJBMGKSVCPC-UHFFFAOYSA-N 50042233 4'-(2-Methyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL325751 Type-1 angiotensin II receptor B Rattus norvegicus 7000 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042233 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042233&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341797 103973841 CHEMBL325751 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067227 CNCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O |r,wU:60.63,wD:24.23,36.36,43.43,56.59,17.16,6.5,(6.84,-31.4,;5.3,-31.4,;4.53,-30.07,;2.99,-30.07,;2.22,-31.4,;2.22,-28.73,;2.99,-27.4,;4.53,-27.4,;5.3,-26.07,;4.53,-24.73,;5.3,-23.4,;6.84,-23.4,;7.61,-24.73,;7.61,-22.07,;2.22,-26.07,;2.99,-24.73,;.68,-26.07,;-.09,-24.73,;.68,-23.4,;2.22,-23.4,;-.09,-22.07,;-1.63,-24.73,;-2.4,-23.4,;-2.4,-26.07,;-3.94,-26.07,;-4.71,-24.73,;-6.25,-24.73,;-7.02,-23.4,;-8.56,-23.4,;-9.33,-24.73,;-10.87,-24.73,;-8.56,-26.07,;-7.02,-26.07,;-4.71,-27.4,;-6.25,-27.4,;-3.94,-28.73,;-4.71,-30.07,;-6.25,-30.07,;-7.02,-28.73,;-7.02,-31.4,;-3.94,-31.4,;-2.4,-31.4,;-4.71,-32.73,;-3.94,-34.07,;-4.71,-35.4,;-6.25,-35.4,;-7.15,-34.16,;-8.62,-34.63,;-8.62,-36.17,;-7.15,-36.65,;-2.4,-34.07,;-1.63,-32.73,;-1.63,-35.4,;-2.26,-36.81,;-1.12,-37.84,;.22,-37.07,;-.1,-35.56,;.93,-34.42,;.45,-32.95,;2.42,-34.82,;3.5,-33.73,;3.11,-32.24,;5,-34.13,;6.09,-33.04,;5.39,-35.61,)| InChI=1S/C42H65N13O10/c1-22(2)33(53-35(58)28(50-32(57)20-45-6)9-7-15-47-42(43)44)38(61)51-29(17-25-11-13-27(56)14-12-25)36(59)54-34(23(3)4)39(62)52-30(18-26-19-46-21-48-26)40(63)55-16-8-10-31(55)37(60)49-24(5)41(64)65/h11-14,19,21-24,28-31,33-34,45,56H,7-10,15-18,20H2,1-6H3,(H,46,48)(H,49,60)(H,50,57)(H,51,61)(H,52,62)(H,53,58)(H,54,59)(H,64,65)(H4,43,44,47) PFGWGEPQIUAZME-UHFFFAOYSA-N 50009338 Sar-Arg-Val-Tyr-Val-His-Pro-Ala::(S)-2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-2-((S)-5-(diaminomethyleneamino)-2-(2-(methylamino)acetamido)pentanamido)-3-methylbutanamido)-3-(4-hydroxyphenyl)propanamido)-3-methylbutanamido)-3-(1H-imidazol-5-yl)propanoyl)pyrrolidine-5-carboxamido)propanoic acid::CHEMBL938::Sar-Arg-Val-Tyr-Val-His-Pro-Ala (sarlasin)::[Sar1-Arg2-Val3-Tyr4-Val5-His6-Pro7-Ala8]::SARALASIN Type-1 angiotensin II receptor B Rattus norvegicus 2.4 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009338 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009338&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 6324663 103922394 CHEMBL938 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067228 CCCCC1=NC2(CCN(CC2)C(=O)C(N)C(C)CC)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C31H40N4O4/c1-4-6-11-26-33-31(16-18-34(19-17-31)28(36)27(32)21(3)5-2)30(39)35(26)20-22-12-14-23(15-13-22)24-9-7-8-10-25(24)29(37)38/h7-10,12-15,21,27H,4-6,11,16-20,32H2,1-3H3,(H,37,38) PNKULEYXNOVYIS-UHFFFAOYSA-N 50042254 4'-[8-(2-Amino-3-methyl-pentanoyl)-2-butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL111968 Type-1 angiotensin II receptor B Rattus norvegicus 730 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042254 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042254&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341488 103973862 CHEMBL111968 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067229 CCCCC1=NC(C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O)(c1ccccc1)c1ccccc1 |t:4| InChI=1S/C33H30N2O3/c1-2-3-18-30-34-33(26-12-6-4-7-13-26,27-14-8-5-9-15-27)32(38)35(30)23-24-19-21-25(22-20-24)28-16-10-11-17-29(28)31(36)37/h4-17,19-22H,2-3,18,23H2,1H3,(H,36,37) SQPLVORXDCZJIZ-UHFFFAOYSA-N 50042256 4'-(2-Butyl-5-oxo-4,4-diphenyl-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL324888 Type-1 angiotensin II receptor B Rattus norvegicus 3000 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042256 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042256&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 19422652 103973864 CHEMBL324888 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067230 CCCCC1=NC2(CCN(CC2)C(=O)C(N)CC(O)=O)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C29H34N4O6/c1-2-3-8-24-31-29(13-15-32(16-14-29)26(36)23(30)17-25(34)35)28(39)33(24)18-19-9-11-20(12-10-19)21-6-4-5-7-22(21)27(37)38/h4-7,9-12,23H,2-3,8,13-18,30H2,1H3,(H,34,35)(H,37,38) GXGGPGKPZOWIIJ-UHFFFAOYSA-N 50042253 4'-[8-(2-Amino-3-carboxy-propionyl)-2-butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL115204 Type-1 angiotensin II receptor B Rattus norvegicus 800 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042253 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042253&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341607 103973861 CHEMBL115204 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067231 CCCCC1=NC(CC(C)C)(CC(C)C)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C29H38N2O3/c1-6-7-12-26-30-29(17-20(2)3,18-21(4)5)28(34)31(26)19-22-13-15-23(16-14-22)24-10-8-9-11-25(24)27(32)33/h8-11,13-16,20-21H,6-7,12,17-19H2,1-5H3,(H,32,33) LUMNPFQMOVLDSQ-UHFFFAOYSA-N 50042241 4'-(2-Butyl-4,4-diisobutyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL45493 Type-1 angiotensin II receptor B Rattus norvegicus 2100 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042241 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042241&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44291654 103973849 CHEMBL45493 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067232 CCCCC1=NC2(CCN(CC2)C(C)=O)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C27H31N3O4/c1-3-4-9-24-28-27(14-16-29(17-15-27)19(2)31)26(34)30(24)18-20-10-12-21(13-11-20)22-7-5-6-8-23(22)25(32)33/h5-8,10-13H,3-4,9,14-18H2,1-2H3,(H,32,33) YRXAHPAFGQQDEX-UHFFFAOYSA-N 50042243 4'-(8-Acetyl-2-butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL115984 Type-1 angiotensin II receptor B Rattus norvegicus 18 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042243 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042243&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341731 103973851 CHEMBL115984 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067233 CCCCC1=NC2(C3CC4CC(C3)CC2C4)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4,TLB:15:14:12:9.8.10,5:6:9.8.15:11.12.13,THB:15:9:12:6.14.13,16:6:9.8.15:11.12.13,5:6:12:9.8.10,10:9:6:11.12.13,10:11:6:9.8.15,(3.07,-11.48,;4.4,-10.72,;4.4,-9.18,;5.71,-8.41,;5.73,-6.86,;4.47,-5.97,;4.95,-4.5,;3.57,-3.93,;3.55,-2.36,;4.59,-1.15,;3.25,-1.6,;3.26,-3.09,;2.08,-4.36,;4.57,-3.58,;5.97,-3.23,;5.97,-1.72,;6.5,-4.49,;7.4,-3.25,;6.98,-5.97,;8.06,-7.04,;9.6,-7.04,;10.35,-5.7,;11.88,-5.7,;12.66,-7.04,;11.89,-8.38,;10.35,-8.38,;14.21,-7.04,;14.95,-5.7,;16.5,-5.68,;17.28,-7.02,;16.51,-8.36,;14.97,-8.36,;14.21,-9.72,;12.66,-9.72,;14.97,-11.03,)| 50042259 2-[4-(2-butyl-5-oxospiro[4,5-dihydro-1H-imidazole-4,2'-tricyclo[3.3.1.13,7]decane]-1-ylmethyl)phenyl]benzoic acid::CHEMBL324452 Type-1 angiotensin II receptor B Rattus norvegicus 62 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042259 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042259&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341836 103973867 CHEMBL324452 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067234 CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnnn1C |t:4| InChI=1S/C26H30N6O/c1-3-4-11-23-27-26(16-7-8-17-26)25(33)32(23)18-19-12-14-20(15-13-19)21-9-5-6-10-22(21)24-28-29-30-31(24)2/h5-6,9-10,12-15H,3-4,7-8,11,16-18H2,1-2H3 YDXKLVLFROFBFN-UHFFFAOYSA-N 50042230 2-Butyl-3-[2'-(1-methyl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one::CHEMBL115193 Type-1 angiotensin II receptor B Rattus norvegicus 150 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042230 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042230&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342089 103973838 CHEMBL115193 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067235 CCCCC1=NC2(CCN(CC2)C(=O)CC(O)=O)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C28H31N3O6/c1-2-3-8-23-29-28(13-15-30(16-14-28)24(32)17-25(33)34)27(37)31(23)18-19-9-11-20(12-10-19)21-6-4-5-7-22(21)26(35)36/h4-7,9-12H,2-3,8,13-18H2,1H3,(H,33,34)(H,35,36) JCOCFIHBICMSOA-UHFFFAOYSA-N 50042237 4'-[2-Butyl-8-(2-carboxy-acetyl)-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL114710 Type-1 angiotensin II receptor B Rattus norvegicus 59 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042237 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042237&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341597 103973845 CHEMBL114710 C01656 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067236 CCCCC1=NC2(CCCC2)C(=S)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C25H28N2O2S/c1-2-3-10-22-26-25(15-6-7-16-25)24(30)27(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23(28)29/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,28,29) WPWLXIFNTAWWKW-UHFFFAOYSA-N 50042258 4'-(2-Butyl-4-thioxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL327018 Type-1 angiotensin II receptor B Rattus norvegicus 80 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042258 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042258&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341802 103973866 CHEMBL327018 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067237 CCCCC1=NC2(CCC(C)CC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4,(3.07,-11.48,;4.4,-10.72,;4.4,-9.18,;5.71,-8.41,;5.74,-6.86,;4.47,-5.97,;4.95,-4.5,;3.44,-4.66,;2.55,-3.42,;3.17,-2.02,;2.27,-.78,;4.69,-1.86,;5.59,-3.1,;6.5,-4.49,;7.4,-3.25,;6.98,-5.97,;8.06,-7.04,;9.6,-7.04,;10.36,-5.7,;11.88,-5.7,;12.66,-7.04,;11.9,-8.38,;10.36,-8.38,;14.21,-7.04,;14.95,-5.7,;16.5,-5.68,;17.28,-7.02,;16.52,-8.36,;14.98,-8.36,;14.21,-9.72,;12.66,-9.72,;14.98,-11.04,)| InChI=1S/C27H32N2O3/c1-3-4-9-24-28-27(16-14-19(2)15-17-27)26(32)29(24)18-20-10-12-21(13-11-20)22-7-5-6-8-23(22)25(30)31/h5-8,10-13,19H,3-4,9,14-18H2,1-2H3,(H,30,31) XVFLOPLAYWVMDD-UHFFFAOYSA-N 50042228 4'-(2-Butyl-8-methyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114656 Type-1 angiotensin II receptor B Rattus norvegicus 66 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042228 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042228&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342002 103973836 CHEMBL114656 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067238 CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C25H28N2O3/c1-2-3-10-22-26-25(15-6-7-16-25)24(30)27(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23(28)29/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,28,29) GJBPPMVTBDRYFK-UHFFFAOYSA-N 50042234 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL439968 Type-1 angiotensin II receptor B Rattus norvegicus 10 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042234 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042234&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 10069786 103973842 CHEMBL439968 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067239 CCCCC1=NC2(CCN(CC2)C(=O)c2ccccc2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C32H33N3O4/c1-2-3-13-28-33-32(18-20-34(21-19-32)29(36)25-9-5-4-6-10-25)31(39)35(28)22-23-14-16-24(17-15-23)26-11-7-8-12-27(26)30(37)38/h4-12,14-17H,2-3,13,18-22H2,1H3,(H,37,38) CUECKDQXOVYNLU-UHFFFAOYSA-N 50042264 4'-(8-Benzoyl-2-butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114720 Type-1 angiotensin II receptor B Rattus norvegicus 49 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042264 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042264&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341756 103973872 CHEMBL114720 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067240 CCCCC1=NC2(CCC(CC2)c2ccccc2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4,(3.08,-11.51,;4.41,-10.74,;4.41,-9.2,;5.73,-8.43,;5.75,-6.88,;4.48,-5.98,;4.96,-4.51,;5.6,-3.11,;4.71,-1.86,;3.17,-2.02,;2.56,-3.43,;3.45,-4.67,;2.28,-.78,;.78,-.94,;-.12,.31,;.51,1.71,;2.02,1.85,;2.92,.61,;6.52,-4.5,;7.42,-3.26,;7,-5.98,;8.08,-7.06,;9.63,-7.06,;10.38,-8.4,;11.93,-8.4,;12.69,-7.06,;11.92,-5.72,;10.38,-5.72,;14.25,-7.06,;14.99,-5.72,;16.55,-5.7,;17.32,-7.04,;16.56,-8.38,;15.01,-8.38,;14.25,-9.74,;12.69,-9.74,;15.01,-11.06,)| InChI=1S/C32H34N2O3/c1-2-3-13-29-33-32(20-18-25(19-21-32)24-9-5-4-6-10-24)31(37)34(29)22-23-14-16-26(17-15-23)27-11-7-8-12-28(27)30(35)36/h4-12,14-17,25H,2-3,13,18-22H2,1H3,(H,35,36) RDEUFLVHGARXDY-UHFFFAOYSA-N 50042245 4'-(2-Butyl-4-oxo-8-phenyl-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL113039 Type-1 angiotensin II receptor B Rattus norvegicus 260 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042245 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042245&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341453 103973853 CHEMBL113039 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067241 CCCCC1=NC(C(C)C)(C(C)C)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C27H34N2O3/c1-6-7-12-24-28-27(18(2)3,19(4)5)26(32)29(24)17-20-13-15-21(16-14-20)22-10-8-9-11-23(22)25(30)31/h8-11,13-16,18-19H,6-7,12,17H2,1-5H3,(H,30,31) VOQCUZNBKUMNFM-UHFFFAOYSA-N 50042261 4'-(2-Butyl-4,4-diisopropyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114687 Type-1 angiotensin II receptor B Rattus norvegicus 20 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042261 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042261&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341670 103973869 CHEMBL114687 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067242 CCCCC1=NC2(CCCC2)CN1Cc1ccc(cc1)-c1ccccc1C(=O)C(C)(C)C |t:4| InChI=1S/C29H38N2O/c1-5-6-13-26-30-29(18-9-10-19-29)21-31(26)20-22-14-16-23(17-15-22)24-11-7-8-12-25(24)27(32)28(2,3)4/h7-8,11-12,14-17H,5-6,9-10,13,18-21H2,1-4H3 DYURUOUOBVIGCU-UHFFFAOYSA-N 50042260 1-[4'-(2-Butyl-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-yl]-2,2-dimethyl-propan-1-one::CHEMBL326049 Type-1 angiotensin II receptor B Rattus norvegicus >10000 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042260 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042260&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341639 103973868 CHEMBL326049 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067243 CCCCC1=NC2(CCN(CC2)C(=O)c2ccccc2C(O)=O)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C33H33N3O6/c1-2-3-12-28-34-33(17-19-35(20-18-33)29(37)25-9-5-7-11-27(25)31(40)41)32(42)36(28)21-22-13-15-23(16-14-22)24-8-4-6-10-26(24)30(38)39/h4-11,13-16H,2-3,12,17-21H2,1H3,(H,38,39)(H,40,41) RUTPNZZFQHFDGZ-UHFFFAOYSA-N 50042262 4'-[2-Butyl-8-(2-carboxy-benzoyl)-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL325905 Type-1 angiotensin II receptor B Rattus norvegicus 480 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042262 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042262&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341608 103973870 CHEMBL325905 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067244 CCCCC1=NC2(CC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C23H24N2O3/c1-2-3-8-20-24-23(13-14-23)22(28)25(20)15-16-9-11-17(12-10-16)18-6-4-5-7-19(18)21(26)27/h4-7,9-12H,2-3,8,13-15H2,1H3,(H,26,27) HZLJBZZTQVIWJK-UHFFFAOYSA-N 50042265 4'-(5-Butyl-7-oxo-4,6-diaza-spiro[2.4]hept-4-en-6-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL325684 Type-1 angiotensin II receptor B Rattus norvegicus 260 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042265 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042265&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342048 103973873 CHEMBL325684 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067245 CCCCC1NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O InChI=1S/C25H30N2O3/c1-2-3-10-22-26-25(15-6-7-16-25)24(30)27(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23(28)29/h4-5,8-9,11-14,22,26H,2-3,6-7,10,15-17H2,1H3,(H,28,29) XAAHVRZYKXNCEC-UHFFFAOYSA-N 50042255 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL324785 Type-1 angiotensin II receptor B Rattus norvegicus 190 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042255 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042255&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341651 103973863 CHEMBL324785 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067246 CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30) YOSHYTLCDANDAN-UHFFFAOYSA-N 50042235 2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::BMS 186295::CHEMBL1513::IRBESARTAN Type-1 angiotensin II receptor B Rattus norvegicus 1.3 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042235 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042235&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 3749 103973843 CHEMBL1513 C07469 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067247 OC(=O)c1ccccc1-c1ccc(CN2C=NC3(CCCC3)C2=O)cc1 |c:16| InChI=1S/C21H20N2O3/c24-19(25)18-6-2-1-5-17(18)16-9-7-15(8-10-16)13-23-14-22-21(20(23)26)11-3-4-12-21/h1-2,5-10,14H,3-4,11-13H2,(H,24,25) UNTVEUKERKKKGW-UHFFFAOYSA-N 50042268 4'-(4-Oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL115937 Type-1 angiotensin II receptor B Rattus norvegicus >10000 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042268 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042268&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342012 103973876 CHEMBL115937 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067248 CCCCC1=NC2(CCN(Cc3ccccc3)CC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C32H35N3O3/c1-2-3-13-29-33-32(18-20-34(21-19-32)22-24-9-5-4-6-10-24)31(38)35(29)23-25-14-16-26(17-15-25)27-11-7-8-12-28(27)30(36)37/h4-12,14-17H,2-3,13,18-23H2,1H3,(H,36,37) UURQJIXVTBCUTF-UHFFFAOYSA-N 50042229 4'-(8-Benzyl-2-butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL112343 Type-1 angiotensin II receptor B Rattus norvegicus 110 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042229 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042229&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342013 103973837 CHEMBL112343 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067249 CCCCC1=NC2(CCCCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C27H32N2O3/c1-2-3-12-24-28-27(17-8-4-5-9-18-27)26(32)29(24)19-20-13-15-21(16-14-20)22-10-6-7-11-23(22)25(30)31/h6-7,10-11,13-16H,2-5,8-9,12,17-19H2,1H3,(H,30,31) BCYZATPCMXUCDR-UHFFFAOYSA-N 50042266 4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.6]undec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL325201 Type-1 angiotensin II receptor B Rattus norvegicus 8.7 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042266 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042266&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342046 103973874 CHEMBL325201 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067250 CCCCC1=NC2(CCN(CC(O)=O)CC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C27H31N3O5/c1-2-3-8-23-28-27(13-15-29(16-14-27)18-24(31)32)26(35)30(23)17-19-9-11-20(12-10-19)21-6-4-5-7-22(21)25(33)34/h4-7,9-12H,2-3,8,13-18H2,1H3,(H,31,32)(H,33,34) JTMFSHYNCXRJGZ-UHFFFAOYSA-N 50042269 4'-(2-Butyl-8-carboxymethyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114590 Type-1 angiotensin II receptor B Rattus norvegicus 950 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042269 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042269&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44342001 103973877 CHEMBL114590 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067251 CCCCC1=NC2(CCOCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C25H28N2O4/c1-2-3-8-22-26-25(13-15-31-16-14-25)24(30)27(22)17-18-9-11-19(12-10-18)20-6-4-5-7-21(20)23(28)29/h4-7,9-12H,2-3,8,13-17H2,1H3,(H,28,29) GVGMYCZEPTXGBF-UHFFFAOYSA-N 50042248 4'-(2-Butyl-4-oxo-8-oxa-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL325445 Type-1 angiotensin II receptor B Rattus norvegicus 47 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042248 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042248&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341792 103973856 CHEMBL325445 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067252 CCCCC1=NC(CCC)(CCC)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C27H34N2O3/c1-4-7-12-24-28-27(17-5-2,18-6-3)26(32)29(24)19-20-13-15-21(16-14-20)22-10-8-9-11-23(22)25(30)31/h8-11,13-16H,4-7,12,17-19H2,1-3H3,(H,30,31) UVJGLBZADFJNOL-UHFFFAOYSA-N 50042267 4'-(2-Butyl-5-oxo-4,4-dipropyl-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL115492 Type-1 angiotensin II receptor B Rattus norvegicus 150 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042267 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042267&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341702 103973875 CHEMBL115492 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067253 OC(=O)c1ccccc1-c1ccc(CN2C(=O)C3(CCCC3)N=C2c2ccccc2)cc1 |c:24| InChI=1S/C27H24N2O3/c30-25(31)23-11-5-4-10-22(23)20-14-12-19(13-15-20)18-29-24(21-8-2-1-3-9-21)28-27(26(29)32)16-6-7-17-27/h1-5,8-15H,6-7,16-18H2,(H,30,31) KTJAGRBGSIVDJU-UHFFFAOYSA-N 50042263 4'-(4-Oxo-2-phenyl-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL423325 Type-1 angiotensin II receptor B Rattus norvegicus 5200 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042263 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042263&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341786 103973871 CHEMBL423325 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067254 CCCCC1=NC2(CCN(CC2)C(=O)C(N)CS)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C28H34N4O4S/c1-2-3-8-24-30-28(13-15-31(16-14-28)25(33)23(29)18-37)27(36)32(24)17-19-9-11-20(12-10-19)21-6-4-5-7-22(21)26(34)35/h4-7,9-12,23,37H,2-3,8,13-18,29H2,1H3,(H,34,35) BMSHADILJXFXJX-UHFFFAOYSA-N 50042270 4'-[8-(2-Amino-3-mercapto-propionyl)-2-butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL114368 Type-1 angiotensin II receptor B Rattus norvegicus 250 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042270 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042270&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341585 103973878 CHEMBL114368 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067255 CCCCC1=NC(C)(C)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C23H26N2O3/c1-4-5-10-20-24-23(2,3)22(28)25(20)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)21(26)27/h6-9,11-14H,4-5,10,15H2,1-3H3,(H,26,27) UCZAVAIIJNHGIP-UHFFFAOYSA-N 50042244 4'-(2-Butyl-4,4-dimethyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL290988 Type-1 angiotensin II receptor B Rattus norvegicus 35 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042244 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042244&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 19422640 103973852 CHEMBL290988 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067256 CCCCC1=NC(C2CC2)(C2CC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C27H30N2O3/c1-2-3-8-24-28-27(20-13-14-20,21-15-16-21)26(32)29(24)17-18-9-11-19(12-10-18)22-6-4-5-7-23(22)25(30)31/h4-7,9-12,20-21H,2-3,8,13-17H2,1H3,(H,30,31) FQVWHIPNXPBODO-UHFFFAOYSA-N 50042239 4'-(2-Butyl-4,4-dicyclopropyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL44268 Type-1 angiotensin II receptor B Rattus norvegicus 80 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042239 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042239&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 19422646 103973847 CHEMBL44268 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089 50067257 CCCCC1=NC2(CCNCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4| InChI=1S/C25H29N3O3/c1-2-3-8-22-27-25(13-15-26-16-14-25)24(31)28(22)17-18-9-11-19(12-10-18)20-6-4-5-7-21(20)23(29)30/h4-7,9-12,26H,2-3,8,13-17H2,1H3,(H,29,30) SLNBALWSFAPJCN-UHFFFAOYSA-N 50042257 4'-(2-Butyl-4-oxo-1,3,8-triaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL114771 Type-1 angiotensin II receptor B Rattus norvegicus 890 ChEMBL 10.1021/jm00074a018 10.7270/Q22Z14M0 8230127 Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clement, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA 12/10/1993 11/10/2009 Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042257 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000273&target=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042257&enzyme=Type-1+angiotensin+II+receptor+B&column=ki&startPg=0&Increment=50&submit=Search 44341791 103973865 CHEMBL114771 1 MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE Type-1 angiotensin II receptor B AGTRB_RAT P29089