BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 163328 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 [3H]-5-HT::5-Hydroxy Tryptamine::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::CHEMBL535832::5-HT::14C-5-hydroxy tryptamine creatinine disulfate::Serotonin::5-hydroxy tryptamine creatinine disulfate::US20240279226, Example Serotonin 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 5202 172097186 CHEMBL535832 C00780 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163329 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 [3H]-5-HT::5-Hydroxy Tryptamine::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::CHEMBL535832::5-HT::14C-5-hydroxy tryptamine creatinine disulfate::Serotonin::5-hydroxy tryptamine creatinine disulfate::US20240279226, Example Serotonin 5-hydroxytryptamine receptor 3A Cavia porcellus 495 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 5202 172097186 CHEMBL535832 C00780 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163330 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 [3H]-5-HT::5-Hydroxy Tryptamine::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::CHEMBL535832::5-HT::14C-5-hydroxy tryptamine creatinine disulfate::Serotonin::5-hydroxy tryptamine creatinine disulfate::US20240279226, Example Serotonin 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 5202 172097186 CHEMBL535832 C00780 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163331 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 BIMU 1::CHEMBL62023::CHEMBL544755::3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Rattus norvegicus 1.6 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000077&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 1 MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLLCLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAVRGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 8CC7,8CC6,6Y1Z 5-hydroxytryptamine receptor 3A 5HT3A_RAT P35563 163332 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 BIMU 1::CHEMBL62023::CHEMBL544755::3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 27.5 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163333 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 BIMU 1::CHEMBL62023::CHEMBL544755::3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 27.5 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163334 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 BIMU 1::CHEMBL62023::CHEMBL544755::3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 0.72 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163335 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 BIMU 1::CHEMBL62023::CHEMBL544755::3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 3981 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163336 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:12:13:20:16.17| InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 BIMU 1::CHEMBL62023::CHEMBL544755::3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 5523 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163337 CC(C)n1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:13:14:21:17.18| InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24) AFOFVIBWSLOHFR-UHFFFAOYSA-N 50056404 BIMU 8::CHEMBL59834::3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 5-hydroxytryptamine receptor 3A Rattus norvegicus 1 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000077&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056404&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 131725 103952676 CHEMBL59834 1 MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLLCLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAVRGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 8CC7,8CC6,6Y1Z 5-hydroxytryptamine receptor 3A 5HT3A_RAT P35563 163338 CC(C)n1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:13:14:21:17.18| InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24) AFOFVIBWSLOHFR-UHFFFAOYSA-N 50056404 BIMU 8::CHEMBL59834::3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 5-hydroxytryptamine receptor 3A Cavia porcellus 20 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056404&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 131725 103952676 CHEMBL59834 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163339 CC(C)n1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:13:14:21:17.18| InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24) AFOFVIBWSLOHFR-UHFFFAOYSA-N 50056404 BIMU 8::CHEMBL59834::3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 5-hydroxytryptamine receptor 3A Cavia porcellus 20 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056404&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 131725 103952676 CHEMBL59834 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163340 CC(C)n1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:13:14:21:17.18| InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24) AFOFVIBWSLOHFR-UHFFFAOYSA-N 50056404 BIMU 8::CHEMBL59834::3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 5-hydroxytryptamine receptor 3A Cavia porcellus 0.78 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056404&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 131725 103952676 CHEMBL59834 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163341 CC(C)n1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:13:14:21:17.18| InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24) AFOFVIBWSLOHFR-UHFFFAOYSA-N 50056404 BIMU 8::CHEMBL59834::3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 5-hydroxytryptamine receptor 3A Cavia porcellus 1259 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056404&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 131725 103952676 CHEMBL59834 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163342 CC(C)n1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O |TLB:13:14:21:17.18| InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24) AFOFVIBWSLOHFR-UHFFFAOYSA-N 50056404 BIMU 8::CHEMBL59834::3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 5-hydroxytryptamine receptor 3A Cavia porcellus 6918 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056404 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056404&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 131725 103952676 CHEMBL59834 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163343 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3 ZZJYIKPMDIWRSN-UHFFFAOYSA-N 50008735 CHEMBL8514::BUTACLAMOL,d-::(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::d-Butaclamol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL,(+)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::BUTACLAMOL::BUTACLAMOL, (-)::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol) 5-hydroxytryptamine receptor 3A Cavia porcellus 3464 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163344 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3 ZZJYIKPMDIWRSN-UHFFFAOYSA-N 50008735 CHEMBL8514::BUTACLAMOL,d-::(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::d-Butaclamol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL,(+)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::BUTACLAMOL::BUTACLAMOL, (-)::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol) 5-hydroxytryptamine receptor 3A Cavia porcellus 944.1 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163345 CCN(CC)CCOC(=O)C1(CCCC1)c1ccccc1 InChI=1S/C18H27NO2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3 OFAIGZWCDGNZGT-UHFFFAOYSA-N 73402 1-phenyl-1-cyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride::CHEMBL61946::2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate;hydrochloride::1-Phenyl-cyclopentanecarboxylic acid 2-diethylamino-ethyl ester::cid_67173::2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate hydrochloride::CARAMIPHEN::SMR000140237::MLS000532799::1-phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73402 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73402&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 6472 252650644 CHEMBL61946 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163346 CCN(CC)CCOCCOC(=O)C1(CCCC1)c1ccccc1 InChI=1S/C20H31NO3/c1-3-21(4-2)14-15-23-16-17-24-19(22)20(12-8-9-13-20)18-10-6-5-7-11-18/h5-7,10-11H,3-4,8-9,12-17H2,1-2H3 CFJMRBQWBDQYMK-UHFFFAOYSA-N 94507 SMR000326757::Carbetapentane citrate::CHEMBL73234::MLS002222257::2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate;2-oxidanylpropane-1,2,3-tricarboxylic acid::2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid::2-hydroxypropane-1,2,3-tricarboxylic acid;1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester::cid_90010::CARBETAPENTANE::citric acid;1-phenylcyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester 5-hydroxytryptamine receptor 3A Cavia porcellus 165 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=94507 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=94507&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 2562 164035751 CHEMBL73234 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163347 CCN(CC)CCOCCOC(=O)C1(CCCC1)c1ccccc1 InChI=1S/C20H31NO3/c1-3-21(4-2)14-15-23-16-17-24-19(22)20(12-8-9-13-20)18-10-6-5-7-11-18/h5-7,10-11H,3-4,8-9,12-17H2,1-2H3 CFJMRBQWBDQYMK-UHFFFAOYSA-N 94507 SMR000326757::Carbetapentane citrate::CHEMBL73234::MLS002222257::2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate;2-oxidanylpropane-1,2,3-tricarboxylic acid::2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid::2-hydroxypropane-1,2,3-tricarboxylic acid;1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester::cid_90010::CARBETAPENTANE::citric acid;1-phenylcyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester 5-hydroxytryptamine receptor 3A Cavia porcellus 7.9 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=94507 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=94507&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 2562 164035751 CHEMBL73234 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163348 CN1C2CCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O |TLB:9:7:1:3.4| InChI=1S/C16H20N4O2/c1-19-11-6-7-12(19)9-10(8-11)17-15(21)20-14-5-3-2-4-13(14)18-16(20)22/h2-5,10-12H,6-9H2,1H3,(H,17,21)(H,18,22) RWXRJSRJIITQAK-UHFFFAOYSA-N 50007892 DAU 6215::CHEMBL539261::2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 6310 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007892 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007892&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 60761 103921160 CHEMBL539261 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163349 CN1C2CCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O |TLB:9:7:1:3.4| InChI=1S/C16H20N4O2/c1-19-11-6-7-12(19)9-10(8-11)17-15(21)20-14-5-3-2-4-13(14)18-16(20)22/h2-5,10-12H,6-9H2,1H3,(H,17,21)(H,18,22) RWXRJSRJIITQAK-UHFFFAOYSA-N 50007892 DAU 6215::CHEMBL539261::2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 2818 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007892 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007892&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 60761 103921160 CHEMBL539261 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163350 Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11| InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18) OPNUROKCUBTKLF-UHFFFAOYSA-N 81982 CAS_97-39-2::cid_7333::Di-o-tolylguanidine::DITOLYLGUANIDINE::DTG::Tol2Gdn 5-hydroxytryptamine receptor 3A Cavia porcellus 57.8 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81982 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81982&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 7333 131342556 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163351 Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11| InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18) OPNUROKCUBTKLF-UHFFFAOYSA-N 81982 CAS_97-39-2::cid_7333::Di-o-tolylguanidine::DITOLYLGUANIDINE::DTG::Tol2Gdn 5-hydroxytryptamine receptor 3A Cavia porcellus 28.8 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81982 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81982&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 7333 131342556 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163352 c1cc(ccc1C(=O)CCCN2CCC(CC2)(c3ccc(cc3)Cl)O)F InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::Haloperidol, 1::CHEMBL545608::CHEMBL54::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::Haloperidol::US20240317745, Compound haloperidol 5-hydroxytryptamine receptor 3A Cavia porcellus 15.4 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 CHEMBL54CHEMBL545608 DB00502 C01814 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163353 c1cc(ccc1C(=O)CCCN2CCC(CC2)(c3ccc(cc3)Cl)O)F InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::Haloperidol, 1::CHEMBL545608::CHEMBL54::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::Haloperidol::US20240317745, Compound haloperidol 5-hydroxytryptamine receptor 3A Cavia porcellus 0.56 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 CHEMBL54CHEMBL545608 DB00502 C01814 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163354 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 |THB:9:7:1:3.4| 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 3A Rattus norvegicus 1.6 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000077&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 5595 103921139 CHEMBL8197 C02089 1 MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLLCLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAVRGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 8CC7,8CC6,6Y1Z 5-hydroxytryptamine receptor 3A 5HT3A_RAT P35563 163355 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 |THB:9:7:1:3.4| 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 3A Cavia porcellus 4332 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 5595 103921139 CHEMBL8197 C02089 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163356 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 |THB:9:7:1:3.4| 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 3A Cavia porcellus 8.41 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 5595 103921139 CHEMBL8197 C02089 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163357 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 |THB:9:7:1:3.4| 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 5595 103921139 CHEMBL8197 C02089 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163358 Cc1nccn1CC2CCc3c(c4ccccc4n3C)C2=O InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 NSC_68647::CAS_68647::ONDANSETRON::Ondansetron hydrochloride 5-hydroxytryptamine receptor 3A Rattus norvegicus 4 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000077&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 4595 136351430 DB00904 C07325 1 MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLLCLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAVRGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 8CC7,8CC6,6Y1Z 5-hydroxytryptamine receptor 3A 5HT3A_RAT P35563 163359 Cc1nccn1CC2CCc3c(c4ccccc4n3C)C2=O InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 NSC_68647::CAS_68647::ONDANSETRON::Ondansetron hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 6383 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 4595 136351430 DB00904 C07325 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163360 Cc1nccn1CC2CCc3c(c4ccccc4n3C)C2=O InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 NSC_68647::CAS_68647::ONDANSETRON::Ondansetron hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 9.62 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 4595 136351430 DB00904 C07325 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163361 Cc1nccn1CC2CCc3c(c4ccccc4n3C)C2=O InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 NSC_68647::CAS_68647::ONDANSETRON::Ondansetron hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 4595 136351430 DB00904 C07325 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163362 [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10| InChI=1S/C19H5NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-6,12,14,18H NTESFUMRHWXLJE-UHFFFAOYSA-N 50001028 Talwin::PENTAZOCINE (+)::Pentazocine,(+/-)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::PENTAZOCINE (-)::(-)-pentazocine::Pentazocine::Talacen::rel-(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL560::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Pentazocine)::(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(+)-PENTAZOCINE::US9656961, Example 00125::US10231963, Table B.8::US10736890, Compound TABLE B.8::US11534436, Compound Table B.8 5-hydroxytryptamine receptor 3A Cavia porcellus 857.7 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001028 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001028&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 441278 103915561 CHEMBL560 DB00652 C07421 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163363 [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10| InChI=1S/C19H5NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-6,12,14,18H NTESFUMRHWXLJE-UHFFFAOYSA-N 50001028 Talwin::PENTAZOCINE (+)::Pentazocine,(+/-)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::PENTAZOCINE (-)::(-)-pentazocine::Pentazocine::Talacen::rel-(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL560::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Pentazocine)::(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(+)-PENTAZOCINE::US9656961, Example 00125::US10231963, Table B.8::US10736890, Compound TABLE B.8::US11534436, Compound Table B.8 5-hydroxytryptamine receptor 3A Cavia porcellus 15.5 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001028 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001028&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 441278 103915561 CHEMBL560 DB00652 C07421 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163364 [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10| InChI=1S/C19H5NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-6,12,14,18H NTESFUMRHWXLJE-UHFFFAOYSA-N 50001028 Talwin::PENTAZOCINE (+)::Pentazocine,(+/-)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::PENTAZOCINE (-)::(-)-pentazocine::Pentazocine::Talacen::rel-(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL560::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Pentazocine)::(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(+)-PENTAZOCINE::US9656961, Example 00125::US10231963, Table B.8::US10736890, Compound TABLE B.8::US11534436, Compound Table B.8 5-hydroxytryptamine receptor 3A Cavia porcellus 195 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001028 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001028&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 441278 103915561 CHEMBL560 DB00652 C07421 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163365 [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10| InChI=1S/C19H5NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-6,12,14,18H NTESFUMRHWXLJE-UHFFFAOYSA-N 50001028 Talwin::PENTAZOCINE (+)::Pentazocine,(+/-)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::PENTAZOCINE (-)::(-)-pentazocine::Pentazocine::Talacen::rel-(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL560::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Pentazocine)::(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(+)-PENTAZOCINE::US9656961, Example 00125::US10231963, Table B.8::US10736890, Compound TABLE B.8::US11534436, Compound Table B.8 5-hydroxytryptamine receptor 3A Cavia porcellus 195 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001028 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001028&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 441278 103915561 CHEMBL560 DB00652 C07421 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163366 c1ccc(cc1)C2(CCCCC2)N3CCCCC3 InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 83449 cid_9795678::PHENCYCLIDINE::SMR001338811::Phencyclidine hydrochloride::PCP hydrochloride::PCP::MLS002320664::1-(1-phenylcyclohexyl)piperidine;hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 2671 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83449 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83449&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 1PC 2PCP,7SAB 6468 252658643 DB03575 C07575 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163367 c1ccc(cc1)C2(CCCCC2)N3CCCCC3 InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 83449 cid_9795678::PHENCYCLIDINE::SMR001338811::Phencyclidine hydrochloride::PCP hydrochloride::PCP::MLS002320664::1-(1-phenylcyclohexyl)piperidine;hydrochloride 5-hydroxytryptamine receptor 3A Cavia porcellus 273 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83449 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83449&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 1PC 2PCP,7SAB 6468 252658643 DB03575 C07575 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163368 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 CAS_85976-54-1::(R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CHEMBL276500::PPP, S(-)-3::NSC_202477::PPP, R(+)-3 5-hydroxytryptamine receptor 3A Cavia porcellus 398.1 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163369 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 CAS_85976-54-1::(R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CHEMBL276500::PPP, S(-)-3::NSC_202477::PPP, R(+)-3 5-hydroxytryptamine receptor 3A Cavia porcellus 2.5 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163370 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C |TLB:16:15:1:10.4.3| InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3 LGQCVMYAEFTEFN-UHFFFAOYSA-N 50001031 SKF 10,047 (-)::CHEMBL330376::SKF 10,047 (+)::SKF 10047::3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001031 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001031&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 44330991 103915564 CHEMBL330376 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163371 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C |TLB:16:15:1:10.4.3| InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3 LGQCVMYAEFTEFN-UHFFFAOYSA-N 50001031 SKF 10,047 (-)::CHEMBL330376::SKF 10,047 (+)::SKF 10047::3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol 5-hydroxytryptamine receptor 3A Cavia porcellus 50.1 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001031 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001031&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 44330991 103915564 CHEMBL330376 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163372 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C |TLB:16:15:1:10.4.3| InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3 LGQCVMYAEFTEFN-UHFFFAOYSA-N 50001031 SKF 10,047 (-)::CHEMBL330376::SKF 10,047 (+)::SKF 10047::3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001031 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001031&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 44330991 103915564 CHEMBL330376 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163373 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C |TLB:16:15:1:10.4.3| InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3 LGQCVMYAEFTEFN-UHFFFAOYSA-N 50001031 SKF 10,047 (-)::CHEMBL330376::SKF 10,047 (+)::SKF 10047::3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol 5-hydroxytryptamine receptor 3A Cavia porcellus 1906 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001031 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001031&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 44330991 103915564 CHEMBL330376 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163374 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Rattus norvegicus 3.2 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000077&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLLCLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAVRGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 8CC7,8CC6,6Y1Z 5-hydroxytryptamine receptor 3A 5HT3A_RAT P35563 163375 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163376 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Cavia porcellus 5.1 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163377 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163378 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Rattus norvegicus 0.32 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000077&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLLCLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAVRGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS 8CC7,8CC6,6Y1Z 5-hydroxytryptamine receptor 3A 5HT3A_RAT P35563 163379 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163380 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Cavia porcellus 0.95 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213 163381 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 ZACOPRIDE,R::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::ZACOPRIDE,S::CHEMBL18041::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::(zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE,RS::ZACOPRIDE 5-hydroxytryptamine receptor 3A Cavia porcellus >10000 PDSP Ki 10.7270/Q2125R5V 8246171 Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH 12/28/1993 1/2/2012 Syntex Discovery Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000072&target=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+3A&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 1 MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDWRKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKFYVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGLLCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPPREASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITLVTLWSVWHYA 5-hydroxytryptamine receptor 3A 5HT3A_CAVPO O70212 O70213