BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50060401 CCCn1c2nc(nc2c2N[C@@H](CC)Cn2c1=O)C12CC3CC1CC(C2)C3 |THB:23:22:19:25.24.26,23:24:19:22.21| 50003022 CHEMBL120350::7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one Adenosine receptor A1 Cavia porcellus 120 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003022 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003022&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 18334308 103917053 CHEMBL120350 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060402 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CC2CCCC2C1 InChI=1S/C19H28N4O2/c1-3-8-22-17-15(18(24)23(9-4-2)19(22)25)20-16(21-17)14-10-12-6-5-7-13(12)11-14/h12-14H,3-11H2,1-2H3,(H,20,21) ZRCSOMMFTYAFJA-UHFFFAOYSA-N 50004583 CHEMBL84144::8-(Octahydro-pentalen-2-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Cavia porcellus 3.5 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004583 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004583&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 44318321 103918172 CHEMBL84144 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060403 COc1cc(\C=C\c2nc3n(C)c(=O)n(C)c(=O)c3n2C)cc(OC)c1OC InChI=1S/C19H22N4O5/c1-21-14(20-17-15(21)18(24)23(3)19(25)22(17)2)8-7-11-9-12(26-4)16(28-6)13(10-11)27-5/h7-10H,1-6H3 KIAYWZXEAJWSGJ-UHFFFAOYSA-N 50006705 CHEMBL27203::1,3,7-Trimethyl-8-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Cavia porcellus >100000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006705 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006705&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 6445882 103920028 CHEMBL27203 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060404 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C12CC3CC1CC(C2)C3 |TLB:20:19:24:21.22,THB:20:21:24:18.19.25| 50044431 8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one::CHEMBL82589 Adenosine receptor A1 Cavia porcellus 1.3 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044431&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 22402388 103975683 CHEMBL82589 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060405 Cn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9) ZFXYFBGIUFBOJW-UHFFFAOYSA-N 10847 Theophylline (1,3-dimethylxanthine)::1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dimethyl-7H-purine-2,6-dione::CHEMBL190::Aminophylline::Euphylline::Theophylline::Aminophyllin::Afonilum::Cardophyllin::Theophy-lline Adenosine receptor A1 Cavia porcellus 23000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10847 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10847&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 2153 46511424 CHEMBL190 DB00277 C07130 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060406 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18) FFBDFADSZUINTG-UHFFFAOYSA-N 21173 DPCPX::CHEMBL183::8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dipropyl-8-cyclopentylxanthine::PD116948::[3H]DPCPX Adenosine receptor A1 Cavia porcellus 6.4 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21173&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 1329 49689246 CHEMBL183 C13709 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060407 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C1CCC(=O)C1 InChI=1S/C21H25N5O3/c1-2-10-26-20(28)17-19(24-18(23-17)14-5-8-16(27)12-14)25(21(26)29)11-9-13-3-6-15(22)7-4-13/h3-4,6-7,14H,2,5,8-12,22H2,1H3,(H,23,24) SYUQQQFRDCSCCA-UHFFFAOYSA-N 50044435 3-[2-(4-Amino-phenyl)-ethyl]-8-(3-oxo-cyclopentyl)-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL83822 Adenosine receptor A1 Cavia porcellus 23 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044435 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044435&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 44318196 103975687 CHEMBL83822 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060408 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C1CC1)C1CC1 InChI=1S/C18H26N4O2/c1-3-9-21-16-14(17(23)22(10-4-2)18(21)24)19-15(20-16)13(11-5-6-11)12-7-8-12/h11-13H,3-10H2,1-2H3,(H,19,20) OEPXIQLEKWHAGE-UHFFFAOYSA-N 50003024 CHEMBL84363::8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::(8-(dicyclopropylmethyl)-1,3-dipropylxanthine)8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 430 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003024 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003024&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 131337 103917055 CHEMBL84363 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50060409 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C12CC3CC1CC(C2)C3 |THB:28:27:24:30.29.31,28:29:24:27.26| 50044432 3-[2-(4-Amino-phenyl)-ethyl]-8-(hexahydro-2,5-methano-pentalen-3a-yl)-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL312857 Adenosine receptor A1 Cavia porcellus 2.4 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044432 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044432&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 3073500 103975684 CHEMBL312857 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060410 CCCn1c2nc(nc2c2NC(CC)Cn2c1=O)C12CC3CC1CC(C2)C3 |THB:23:22:19:25.24.26,23:24:19:22.21| 50003023 CHEMBL312352::7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one Adenosine receptor A1 Cavia porcellus 5.7 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003023 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003023&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 5464024 103917054 CHEMBL312352 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060411 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C1CCCC1 InChI=1S/C16H24N4OS/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18) ZRVSACYKNPKHRS-UHFFFAOYSA-N 50018420 CHEMBL292904::8-Cyclopentyl-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one Adenosine receptor A1 Cavia porcellus 6.6 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018420 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018420&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 10471265 103929576 CHEMBL292904 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060412 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C1CC1)C1CC1 InChI=1S/C18H26N4O2/c1-3-9-21-16-14(17(23)22(10-4-2)18(21)24)19-15(20-16)13(11-5-6-11)12-7-8-12/h11-13H,3-10H2,1-2H3,(H,19,20) OEPXIQLEKWHAGE-UHFFFAOYSA-N 50003024 CHEMBL84363::8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::(8-(dicyclopropylmethyl)-1,3-dipropylxanthine)8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Cavia porcellus 3 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003024 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003024&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 131337 103917055 CHEMBL84363 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060413 CC(C)Cn1c2nc([nH]c2c(=O)n(C)c1=O)C(C1CC1)C1CC1 InChI=1S/C17H24N4O2/c1-9(2)8-21-15-13(16(22)20(3)17(21)23)18-14(19-15)12(10-4-5-10)11-6-7-11/h9-12H,4-8H2,1-3H3,(H,18,19) GKLKHJBKPRFKON-UHFFFAOYSA-N 50004586 CHEMBL313780::8-Dicyclopropylmethyl-3-isobutyl-1-methyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Cavia porcellus 12 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004586 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004586&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15667112 103918175 CHEMBL313780 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060414 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C21H27N5O2/c1-2-12-26-20(27)17-19(24-18(23-17)15-5-3-4-6-15)25(21(26)28)13-11-14-7-9-16(22)10-8-14/h7-10,15H,2-6,11-13,22H2,1H3,(H,23,24) HIGUCTFSOVUIFC-UHFFFAOYSA-N 50044429 3-[2-(4-Amino-phenyl)-ethyl]-8-cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL310557 Adenosine receptor A1 Cavia porcellus 5.6 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044429&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15235760 103975681 CHEMBL310557 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060415 CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3 UQGGPCQNHJCOPS-UHFFFAOYSA-N 50006710 8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL27508::8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione; compound with 8-[2-(3,4-dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL1795043::KF-17837 Adenosine receptor A1 Cavia porcellus 1500 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006710 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006710&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 6448585 103920033 CHEMBL1795043CHEMBL27508 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060416 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C(C1CC1)C1CC1 InChI=1S/C18H26N4OS/c1-3-9-21-16-14(17(23)22(10-4-2)18(21)24)19-15(20-16)13(11-5-6-11)12-7-8-12/h11-13H,3-10H2,1-2H3,(H,19,20) PHSVHWIHVRHART-UHFFFAOYSA-N 50044430 8-Dicyclopropylmethyl-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one::CHEMBL82417 Adenosine receptor A1 Cavia porcellus 6.1 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044430 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044430&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15010014 103975682 CHEMBL82417 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060417 CCCn1c2nc(nc2c2N[C@H](CC)Cn2c1=O)C12CC3CC1CC(C2)C3 |THB:23:22:19:25.24.26,23:24:19:22.21| 50003021 CHEMBL116486::7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one Adenosine receptor A1 Cavia porcellus 2.7 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003021 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003021&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 18334304 103917052 CHEMBL116486 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060418 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C12CC3CC(CC(C3)C1)C2 |TLB:24:19:26:25.23.22,24:23:26:18.19.20,20:21:25:18.19.24,THB:20:19:25:26.21.22| 50004587 CHEMBL418101::8-Adamantan-1-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Cavia porcellus 13 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004587 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004587&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14788226 103918176 CHEMBL418101 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50060419 Cn1cnc2c1C(=O)N(C(=O)N2C)C InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3 RYYVLZVUVIJVGH-UHFFFAOYSA-N 10849 CHEMBL113::1,3,7-trimethyl-3,7-dihydropurine-2,6-dione::1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::Caffeine (1,3,7-trimethylxanthine)::caffeine Adenosine receptor A1 Cavia porcellus 100000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10849 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10849&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search CFF 1C8L,1GFZ,1L5Q,1L7X,2A3B,3DD1,3DDS,3DDW,3G6M,3RFM,4Y4D,5MZP,5T9V,5TA3,5TAL,5TAM,5TAN,5TAP,5TAQ,5TAS,5TAT,5TAU,5TAV,6ICN,6ICP,6JHN,6JI0,6JII,6JIU,6JIY,6JRR,6JRS,6M2W,6QTL,6SF9,6TV4,6UG4,7D7K,7D7L,7H8S,7M6A,7M6L,7PBB,7TZC,8DRP,8DTB,8DUJ,8DVE,8FTG,8OPW,8R4J,8R6V,8RRS,8RRT,8RRU,8RRW,8RRX,8RS0,8SJK,8SO1,8SO2,8UZD,8VJK,8VK4,8XJI,8XKH,8XLF,8XLH,8Y40,9C1F,9E17,9GNY,9HEO,9HEQ,9NMN,9NMO,9NMP,9NMQ,9O2B,9OL4,9PWO,9R8O,9RCW,9XUA 2519 46511425 CHEMBL113 DB00201 C07481 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50670969 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C21H27N5O2/c1-2-12-26-20(27)17-19(24-18(23-17)15-5-3-4-6-15)25(21(26)28)13-11-14-7-9-16(22)10-8-14/h7-10,15H,2-6,11-13,22H2,1H3,(H,23,24) HIGUCTFSOVUIFC-UHFFFAOYSA-N 50044429 3-[2-(4-Amino-phenyl)-ethyl]-8-cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL310557 Adenosine receptor A2a/A2b Rattus norvegicus 430 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044429&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15235760 103975681 CHEMBL310557 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50670991 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C(C1CC1)C1CC1 InChI=1S/C18H26N4OS/c1-3-9-21-16-14(17(23)22(10-4-2)18(21)24)19-15(20-16)13(11-5-6-11)12-7-8-12/h11-13H,3-10H2,1-2H3,(H,19,20) PHSVHWIHVRHART-UHFFFAOYSA-N 50044430 8-Dicyclopropylmethyl-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one::CHEMBL82417 Adenosine receptor A2a/A2b Rattus norvegicus 2000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044430 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044430&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15010014 103975682 CHEMBL82417 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50670995 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CC2CCCC2C1 InChI=1S/C19H28N4O2/c1-3-8-22-17-15(18(24)23(9-4-2)19(22)25)20-16(21-17)14-10-12-6-5-7-13(12)11-14/h12-14H,3-11H2,1-2H3,(H,20,21) ZRCSOMMFTYAFJA-UHFFFAOYSA-N 50004583 CHEMBL84144::8-(Octahydro-pentalen-2-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 330 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004583 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004583&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 44318321 103918172 CHEMBL84144 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671000 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C12CC3CC1CC(C2)C3 |TLB:20:19:24:21.22,THB:20:21:24:18.19.25| 50044431 8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one::CHEMBL82589 Adenosine receptor A2a/A2b Rattus norvegicus 380 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044431&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 22402388 103975683 CHEMBL82589 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671005 CC(C)Cn1c2nc([nH]c2c(=O)n(C)c1=O)C(C1CC1)C1CC1 InChI=1S/C17H24N4O2/c1-9(2)8-21-15-13(16(22)20(3)17(21)23)18-14(19-15)12(10-4-5-10)11-6-7-11/h9-12H,4-8H2,1-3H3,(H,18,19) GKLKHJBKPRFKON-UHFFFAOYSA-N 50004586 CHEMBL313780::8-Dicyclopropylmethyl-3-isobutyl-1-methyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 410 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004586 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004586&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15667112 103918175 CHEMBL313780 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671038 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C12CC3CC1CC(C2)C3 |THB:28:27:24:30.29.31,28:29:24:27.26| 50044432 3-[2-(4-Amino-phenyl)-ethyl]-8-(hexahydro-2,5-methano-pentalen-3a-yl)-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL312857 Adenosine receptor A2a/A2b Rattus norvegicus >100000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044432 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044432&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 3073500 103975684 CHEMBL312857 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671049 CCCn1c(=O)n(CCc2ccc(NC(C)=O)cc2)c2[nH]c(nc2c1=O)C1CCCC1 InChI=1S/C23H29N5O3/c1-3-13-28-22(30)19-21(26-20(25-19)17-6-4-5-7-17)27(23(28)31)14-12-16-8-10-18(11-9-16)24-15(2)29/h8-11,17H,3-7,12-14H2,1-2H3,(H,24,29)(H,25,26) XOFKHHZMYBONCM-UHFFFAOYSA-N 50231015 CHEMBL421526 Adenosine receptor A2a/A2b Homo sapiens >100000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231015 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000781&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231015&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 3073504 381616771 CHEMBL421526 2 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS 9EEA,9EE9,9EE8,5UIG,8JWZ,8JWY,3QAK,3EML,5WF6,5WF5,7T32,5OM4,5OM1,5OLZ,5OLV,5OLO,5OLH,5OLG,5MZJ,9H37,9H2X,8PWN,7ARO,6ZDV,6ZDR,6S0Q,6S0L,6GT3,5NM4,5NM2,5NLX,5N2R,5MZP,5IUB,5IUA,5IU8,5IU7,5IU4 Adenosine receptor A2a AA2AR_HUMAN P29274 B2R7E0 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL 7XY7,7XY6,8HDP,8HDO Adenosine receptor A2b AA2BR_HUMAN P29275 50671081 COc1cc(\C=C\c2nc3n(C)c(=O)n(C)c(=O)c3n2C)cc(OC)c1OC InChI=1S/C19H22N4O5/c1-21-14(20-17-15(21)18(24)23(3)19(25)22(17)2)8-7-11-9-12(26-4)16(28-6)13(10-11)27-5/h7-10H,1-6H3 KIAYWZXEAJWSGJ-UHFFFAOYSA-N 50006705 CHEMBL27203::1,3,7-Trimethyl-8-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 18 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006705 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006705&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 6445882 103920028 CHEMBL27203 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671095 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C12CC3CC(CC(C3)C1)C2 |TLB:24:19:26:25.23.22,24:23:26:18.19.20,20:21:25:18.19.24,THB:20:19:25:26.21.22| 50004587 CHEMBL418101::8-Adamantan-1-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 5100 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004587 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004587&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 14788226 103918176 CHEMBL418101 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671096 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C1CCC(=O)C1 InChI=1S/C21H25N5O3/c1-2-10-26-20(28)17-19(24-18(23-17)14-5-8-16(27)12-14)25(21(26)29)11-9-13-3-6-15(22)7-4-13/h3-4,6-7,14H,2,5,8-12,22H2,1H3,(H,23,24) SYUQQQFRDCSCCA-UHFFFAOYSA-N 50044435 3-[2-(4-Amino-phenyl)-ethyl]-8-(3-oxo-cyclopentyl)-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL83822 Adenosine receptor A2a/A2b Rattus norvegicus >100000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044435 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044435&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 44318196 103975687 CHEMBL83822 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671097 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCC(=O)C1 InChI=1S/C16H22N4O3/c1-3-7-19-14-12(15(22)20(8-4-2)16(19)23)17-13(18-14)10-5-6-11(21)9-10/h10H,3-9H2,1-2H3,(H,17,18) RUHGOZFOVBMWOO-UHFFFAOYSA-N 50003018 CHEMBL84545::8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Homo sapiens 1512 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003018 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000781&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003018&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 131584 103917050 CHEMBL84545 2 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS 9EEA,9EE9,9EE8,5UIG,8JWZ,8JWY,3QAK,3EML,5WF6,5WF5,7T32,5OM4,5OM1,5OLZ,5OLV,5OLO,5OLH,5OLG,5MZJ,9H37,9H2X,8PWN,7ARO,6ZDV,6ZDR,6S0Q,6S0L,6GT3,5NM4,5NM2,5NLX,5N2R,5MZP,5IUB,5IUA,5IU8,5IU7,5IU4 Adenosine receptor A2a AA2AR_HUMAN P29274 B2R7E0 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL 7XY7,7XY6,8HDP,8HDO Adenosine receptor A2b AA2BR_HUMAN P29275 50671101 CCCn1c(=O)n(CCc2ccc(NC(=O)C(C)C)cc2)c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C25H33N5O3/c1-4-14-30-24(32)20-22(28-21(27-20)18-7-5-6-8-18)29(25(30)33)15-13-17-9-11-19(12-10-17)26-23(31)16(2)3/h9-12,16,18H,4-8,13-15H2,1-3H3,(H,26,31)(H,27,28) KBTUYCVPQYWRQO-UHFFFAOYSA-N 50044433 N-{4-[2-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-purin-3-yl)-ethyl]-phenyl}-isobutyramide::CHEMBL82222 Adenosine receptor A2a/A2b Homo sapiens >100000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044433 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000781&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044433&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15235763 103975685 CHEMBL82222 2 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS 9EEA,9EE9,9EE8,5UIG,8JWZ,8JWY,3QAK,3EML,5WF6,5WF5,7T32,5OM4,5OM1,5OLZ,5OLV,5OLO,5OLH,5OLG,5MZJ,9H37,9H2X,8PWN,7ARO,6ZDV,6ZDR,6S0Q,6S0L,6GT3,5NM4,5NM2,5NLX,5N2R,5MZP,5IUB,5IUA,5IU8,5IU7,5IU4 Adenosine receptor A2a AA2AR_HUMAN P29274 B2R7E0 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL 7XY7,7XY6,8HDP,8HDO Adenosine receptor A2b AA2BR_HUMAN P29275 50671102 CCCn1c2nc(nc2c2N[C@@H](CC)Cn2c1=O)C12CC3CC1CC(C2)C3 |THB:23:22:19:25.24.26,23:24:19:22.21| 50003022 CHEMBL120350::7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one Adenosine receptor A2a/A2b Rattus norvegicus 250 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003022 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003022&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 18334308 103917053 CHEMBL120350 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671108 Cn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9) ZFXYFBGIUFBOJW-UHFFFAOYSA-N 10847 Theophylline (1,3-dimethylxanthine)::1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dimethyl-7H-purine-2,6-dione::CHEMBL190::Aminophylline::Euphylline::Theophylline::Aminophyllin::Afonilum::Cardophyllin::Theophy-lline Adenosine receptor A2a/A2b Rattus norvegicus 16000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10847 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10847&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 2153 46511424 CHEMBL190 DB00277 C07130 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671109 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18) FFBDFADSZUINTG-UHFFFAOYSA-N 21173 DPCPX::CHEMBL183::8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dipropyl-8-cyclopentylxanthine::PD116948::[3H]DPCPX Adenosine receptor A2a/A2b Rattus norvegicus 590 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21173&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 1329 49689246 CHEMBL183 C13709 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671111 CCCn1c2nc(nc2c2N[C@H](CC)Cn2c1=O)C12CC3CC1CC(C2)C3 |THB:23:22:19:25.24.26,23:24:19:22.21| 50003021 CHEMBL116486::7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one Adenosine receptor A2a/A2b Rattus norvegicus 290 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003021 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003021&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 18334304 103917052 CHEMBL116486 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671130 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCC(=O)C1 InChI=1S/C16H22N4O3/c1-3-7-19-14-12(15(22)20(8-4-2)16(19)23)17-13(18-14)10-5-6-11(21)9-10/h10H,3-9H2,1-2H3,(H,17,18) RUHGOZFOVBMWOO-UHFFFAOYSA-N 50003018 CHEMBL84545::8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A2a/A2b Rattus norvegicus 2700 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003018 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003018&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 131584 103917050 CHEMBL84545 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671133 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C21H27N5O2/c1-2-12-26-20(27)17-19(24-18(23-17)15-5-3-4-6-15)25(21(26)28)13-11-14-7-9-16(22)10-8-14/h7-10,15H,2-6,11-13,22H2,1H3,(H,23,24) HIGUCTFSOVUIFC-UHFFFAOYSA-N 50044429 3-[2-(4-Amino-phenyl)-ethyl]-8-cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL310557 Adenosine receptor A2a/A2b Homo sapiens 2000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50000781&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044429&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 15235760 103975681 CHEMBL310557 2 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS 9EEA,9EE9,9EE8,5UIG,8JWZ,8JWY,3QAK,3EML,5WF6,5WF5,7T32,5OM4,5OM1,5OLZ,5OLV,5OLO,5OLH,5OLG,5MZJ,9H37,9H2X,8PWN,7ARO,6ZDV,6ZDR,6S0Q,6S0L,6GT3,5NM4,5NM2,5NLX,5N2R,5MZP,5IUB,5IUA,5IU8,5IU7,5IU4 Adenosine receptor A2a AA2AR_HUMAN P29274 B2R7E0 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL 7XY7,7XY6,8HDP,8HDO Adenosine receptor A2b AA2BR_HUMAN P29275 50671151 CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3 UQGGPCQNHJCOPS-UHFFFAOYSA-N 50006710 8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL27508::8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione; compound with 8-[2-(3,4-dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL1795043::KF-17837 Adenosine receptor A2a/A2b Rattus norvegicus 7.8 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006710 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006710&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 6448585 103920033 CHEMBL1795043CHEMBL27508 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671152 CCCn1c2nc(nc2c2NC(CC)Cn2c1=O)C12CC3CC1CC(C2)C3 |THB:23:22:19:25.24.26,23:24:19:22.21| 50003023 CHEMBL312352::7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one Adenosine receptor A2a/A2b Rattus norvegicus 330 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003023 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003023&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 5464024 103917054 CHEMBL312352 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671154 Cn1cnc2c1C(=O)N(C(=O)N2C)C InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3 RYYVLZVUVIJVGH-UHFFFAOYSA-N 10849 CHEMBL113::1,3,7-trimethyl-3,7-dihydropurine-2,6-dione::1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::Caffeine (1,3,7-trimethylxanthine)::caffeine Adenosine receptor A2a/A2b Rattus norvegicus 27000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10849 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10849&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search CFF 1C8L,1GFZ,1L5Q,1L7X,2A3B,3DD1,3DDS,3DDW,3G6M,3RFM,4Y4D,5MZP,5T9V,5TA3,5TAL,5TAM,5TAN,5TAP,5TAQ,5TAS,5TAT,5TAU,5TAV,6ICN,6ICP,6JHN,6JI0,6JII,6JIU,6JIY,6JRR,6JRS,6M2W,6QTL,6SF9,6TV4,6UG4,7D7K,7D7L,7H8S,7M6A,7M6L,7PBB,7TZC,8DRP,8DTB,8DUJ,8DVE,8FTG,8OPW,8R4J,8R6V,8RRS,8RRT,8RRU,8RRW,8RRX,8RS0,8SJK,8SO1,8SO2,8UZD,8VJK,8VK4,8XJI,8XKH,8XLF,8XLH,8Y40,9C1F,9E17,9GNY,9HEO,9HEQ,9NMN,9NMO,9NMP,9NMQ,9O2B,9OL4,9PWO,9R8O,9RCW,9XUA 2519 46511425 CHEMBL113 DB00201 C07481 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671161 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C1CCCC1 InChI=1S/C16H24N4OS/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18) ZRVSACYKNPKHRS-UHFFFAOYSA-N 50018420 CHEMBL292904::8-Cyclopentyl-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one Adenosine receptor A2a/A2b Rattus norvegicus >10000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018420 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50005864&target=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018420&enzyme=Adenosine+receptor+A2a%2FA2b&column=ki&startPg=0&Increment=50&submit=Search 10471265 103929576 CHEMBL292904 2 MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS Adenosine receptor A2a AA2AR_RAT P30543 MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL Adenosine receptor A2b AA2BR_RAT P29276 50671162 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCC(=O)C1 InChI=1S/C16H22N4O3/c1-3-7-19-14-12(15(22)20(8-4-2)16(19)23)17-13(18-14)10-5-6-11(21)9-10/h10H,3-9H2,1-2H3,(H,17,18) RUHGOZFOVBMWOO-UHFFFAOYSA-N 50003018 CHEMBL84545::8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Homo sapiens 11 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003018 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2129&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003018&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 131584 103917050 CHEMBL84545 1 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD 7LD4,7LD3,6D9H,5UEN Adenosine receptor A1 AA1R_HUMAN P30542 A6NFY5 A6NGP4 A8K1L3 B3KXQ4 D2CGD0 Q6FHK3 Q8TAM8 50764878 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CC2CCCC2C1 InChI=1S/C19H28N4O2/c1-3-8-22-17-15(18(24)23(9-4-2)19(22)25)20-16(21-17)14-10-12-6-5-7-13(12)11-14/h12-14H,3-11H2,1-2H3,(H,20,21) ZRCSOMMFTYAFJA-UHFFFAOYSA-N 50004583 CHEMBL84144::8-(Octahydro-pentalen-2-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 0.750000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004583 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004583&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 44318321 103918172 CHEMBL84144 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764882 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C12CC3CC(CC(C3)C1)C2 |TLB:24:19:26:25.23.22,24:23:26:18.19.20,20:21:25:18.19.24,THB:20:19:25:26.21.22| 50004587 CHEMBL418101::8-Adamantan-1-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 1.5 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004587 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004587&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 14788226 103918176 CHEMBL418101 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764892 CCCn1c(=O)n(CCc2ccc(NC(=O)C(C)C)cc2)c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C25H33N5O3/c1-4-14-30-24(32)20-22(28-21(27-20)18-7-5-6-8-18)29(25(30)33)15-13-17-9-11-19(12-10-17)26-23(31)16(2)3/h9-12,16,18H,4-8,13-15H2,1-3H3,(H,26,31)(H,27,28) KBTUYCVPQYWRQO-UHFFFAOYSA-N 50044433 N-{4-[2-(8-Cyclopentyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-purin-3-yl)-ethyl]-phenyl}-isobutyramide::CHEMBL82222 Adenosine receptor A1 Bos taurus 16 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044433 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000132&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044433&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15235763 103975685 CHEMBL82222 1 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD Adenosine receptor A1 AA1R_BOVIN P28190 A5PJR1 Q58D38 50764893 CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3 UQGGPCQNHJCOPS-UHFFFAOYSA-N 50006710 8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL27508::8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione; compound with 8-[2-(3,4-dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL1795043::KF-17837 Adenosine receptor A1 Rattus norvegicus 430 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006710 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006710&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 6448585 103920033 CHEMBL1795043CHEMBL27508 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764896 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 InChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18) FFBDFADSZUINTG-UHFFFAOYSA-N 21173 DPCPX::CHEMBL183::8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dipropyl-8-cyclopentylxanthine::PD116948::[3H]DPCPX Adenosine receptor A1 Rattus norvegicus 0.460000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21173 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21173&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 1329 49689246 CHEMBL183 C13709 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764897 CCCn1c2nc(nc2c2N[C@H](CC)Cn2c1=O)C12CC3CC1CC(C2)C3 |THB:23:22:19:25.24.26,23:24:19:22.21| 50003021 CHEMBL116486::7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one Adenosine receptor A1 Rattus norvegicus 0.560000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003021 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003021&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 18334304 103917052 CHEMBL116486 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764899 Cn1c2nc[nH]c2c(=O)n(C)c1=O InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9) ZFXYFBGIUFBOJW-UHFFFAOYSA-N 10847 Theophylline (1,3-dimethylxanthine)::1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::1,3-dimethyl-7H-purine-2,6-dione::CHEMBL190::Aminophylline::Euphylline::Theophylline::Aminophyllin::Afonilum::Cardophyllin::Theophy-lline Adenosine receptor A1 Rattus norvegicus 8470 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10847 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10847&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 2153 46511424 CHEMBL190 DB00277 C07130 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764909 CCCn1c(=O)n(CCc2ccc(N)cc2)c2nc([nH]c2c1=O)C1CCCC1 InChI=1S/C21H27N5O2/c1-2-12-26-20(27)17-19(24-18(23-17)15-5-3-4-6-15)25(21(26)28)13-11-14-7-9-16(22)10-8-14/h7-10,15H,2-6,11-13,22H2,1H3,(H,23,24) HIGUCTFSOVUIFC-UHFFFAOYSA-N 50044429 3-[2-(4-Amino-phenyl)-ethyl]-8-cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione::CHEMBL310557 Adenosine receptor A1 Bos taurus 0.230000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044429 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000132&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044429&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 15235760 103975681 CHEMBL310557 1 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD Adenosine receptor A1 AA1R_BOVIN P28190 A5PJR1 Q58D38 50764910 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=S)C12CC3CC1CC(C2)C3 |TLB:20:19:24:21.22,THB:20:21:24:18.19.25| 50044431 8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipropyl-2-thioxo-1,2,3,7-tetrahydro-purin-6-one::CHEMBL82589 Adenosine receptor A1 Rattus norvegicus 0.190000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044431&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 22402388 103975683 CHEMBL82589 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764912 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCC(=O)C1 InChI=1S/C16H22N4O3/c1-3-7-19-14-12(15(22)20(8-4-2)16(19)23)17-13(18-14)10-5-6-11(21)9-10/h10H,3-9H2,1-2H3,(H,17,18) RUHGOZFOVBMWOO-UHFFFAOYSA-N 50003018 CHEMBL84545::8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Cavia porcellus 15 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003018 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000138&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003018&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 131584 103917050 CHEMBL84545 1 MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD 5N2S Adenosine receptor A1 AA1R_CAVPO P47745 50764917 Cn1cnc2c1C(=O)N(C(=O)N2C)C InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3 RYYVLZVUVIJVGH-UHFFFAOYSA-N 10849 CHEMBL113::1,3,7-trimethyl-3,7-dihydropurine-2,6-dione::1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::Caffeine (1,3,7-trimethylxanthine)::caffeine Adenosine receptor A1 Rattus norvegicus 29100 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10849 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10849&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search CFF 1C8L,1GFZ,1L5Q,1L7X,2A3B,3DD1,3DDS,3DDW,3G6M,3RFM,4Y4D,5MZP,5T9V,5TA3,5TAL,5TAM,5TAN,5TAP,5TAQ,5TAS,5TAT,5TAU,5TAV,6ICN,6ICP,6JHN,6JI0,6JII,6JIU,6JIY,6JRR,6JRS,6M2W,6QTL,6SF9,6TV4,6UG4,7D7K,7D7L,7H8S,7M6A,7M6L,7PBB,7TZC,8DRP,8DTB,8DUJ,8DVE,8FTG,8OPW,8R4J,8R6V,8RRS,8RRT,8RRU,8RRW,8RRX,8RS0,8SJK,8SO1,8SO2,8UZD,8VJK,8VK4,8XJI,8XKH,8XLF,8XLH,8Y40,9C1F,9E17,9GNY,9HEO,9HEQ,9NMN,9NMO,9NMP,9NMQ,9O2B,9OL4,9PWO,9R8O,9RCW,9XUA 2519 46511425 CHEMBL113 DB00201 C07481 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099 50764921 CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C1CC1)C1CC1 InChI=1S/C18H26N4O2/c1-3-9-21-16-14(17(23)22(10-4-2)18(21)24)19-15(20-16)13(11-5-6-11)12-7-8-12/h11-13H,3-10H2,1-2H3,(H,19,20) OEPXIQLEKWHAGE-UHFFFAOYSA-N 50003024 CHEMBL84363::8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::(8-(dicyclopropylmethyl)-1,3-dipropylxanthine)8-Dicyclopropylmethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione Adenosine receptor A1 Rattus norvegicus 0.990000 ChEMBL 10.1021/jm00069a009 10.7270/Q2GX4C5K 8355252 Suzuki, F; Shimada, J; Shiozaki, S; Ichikawa, S; Ishii, A; Nakamura, J; Nonaka, H; Kobayashi, H; Fuse, E 9/23/1993 10/25/2012 Kyowa Hakko Kogyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003024 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=5768&target=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003024&enzyme=Adenosine+receptor+A1&column=ki&startPg=0&Increment=50&submit=Search 131337 103917055 CHEMBL84363 1 MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED Adenosine receptor A1 AA1R_RAT P25099