BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50060441 CCCCc1nn(CC(C)(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H31N7O/c1-5-6-11-22-28-32(17-25(2,3)4)24(33)31(22)16-18-12-14-19(15-13-18)20-9-7-8-10-21(20)23-26-29-30-27-23/h7-10,12-15H,5-6,11,16-17H2,1-4H3,(H,26,27,29,30) XWUOBJXGWLLBPU-UHFFFAOYSA-N 50044503 5-Butyl-2-(2,2-dimethyl-propyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL19202 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.1 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044503 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044503&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956779 103975741 CHEMBL19202 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060442 CCCCc1nn(-c2ccccc2[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24N8O3/c1-2-3-12-24-29-33(22-10-6-7-11-23(22)34(36)37)26(35)32(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-27-30-31-28-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,27,28,30,31) DEYPAOCOYLNSFR-UHFFFAOYSA-N 50044518 5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-(2-nitro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87074 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.850000 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044518 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044518&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956739 103975756 CHEMBL87074 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060443 CCCCc1nn(Cc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O/c1-2-3-13-25-30-34(19-20-9-5-4-6-10-20)27(35)33(25)18-21-14-16-22(17-15-21)23-11-7-8-12-24(23)26-28-31-32-29-26/h4-12,14-17H,2-3,13,18-19H2,1H3,(H,28,29,31,32) CLIGTAMVAYBTCT-UHFFFAOYSA-N 50044344 2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::2-Benzyl-5-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL422593 Type-1 angiotensin II receptor Oryctolagus cuniculus 4.6 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044344 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044344&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10183373 103975599 CHEMBL422593 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060444 CCCCc1nn(-c2ccccc2C(O)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H25N7O3/c1-2-3-12-24-30-34(23-11-7-6-10-22(23)26(35)36)27(37)33(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-28-31-32-29-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,35,36)(H,28,29,31,32) MFYOOXJZGZRPSX-UHFFFAOYSA-N 50044492 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-benzoic acid::CHEMBL85704 Type-1 angiotensin II receptor Oryctolagus cuniculus 50 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044492&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956759 103975730 CHEMBL85704 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060445 CCCCc1nn(C(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C23H27N7O/c1-4-5-10-21-26-30(16(2)3)23(31)29(21)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14,16H,4-5,10,15H2,1-3H3,(H,24,25,27,28) HUUJBXWDCSBHBP-UHFFFAOYSA-N 50044351 5-Butyl-2-isopropyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-isopropyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87985 Type-1 angiotensin II receptor Oryctolagus cuniculus 7.7 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044351 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044351&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10202093 103975606 CHEMBL87985 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060446 CCCCc1nn(C(C(C)C)C(O)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H29N7O3/c1-4-5-10-21-28-32(22(16(2)3)24(33)34)25(35)31(21)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-26-29-30-27-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,33,34)(H,26,27,29,30) XSILPQTUKBRCSE-UHFFFAOYSA-N 50044513 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-3-methyl-butyric acid::CHEMBL446152 Type-1 angiotensin II receptor Oryctolagus cuniculus 70 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044513 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044513&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956790 103975751 CHEMBL446152 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060447 CCCCc1nn(CCCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H29N7O/c1-3-5-11-22-27-31(16-6-4-2)24(32)30(22)17-18-12-14-19(15-13-18)20-9-7-8-10-21(20)23-25-28-29-26-23/h7-10,12-15H,3-6,11,16-17H2,1-2H3,(H,25,26,28,29) STODEQQYGGTXOS-UHFFFAOYSA-N 50044355 2,5-Dibutyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one(SC-15316)::2,5-Dibutyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-[1,2,4]triazolidin-3-one::2,5-Dibutyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87778 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.9 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044355&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 131654 103975610 CHEMBL87778 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060448 CCCCc1nn(-c2ccc(cc2)C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O3/c1-3-4-9-25-31-35(22-16-14-21(15-17-22)27(36)38-2)28(37)34(25)18-19-10-12-20(13-11-19)23-7-5-6-8-24(23)26-29-32-33-30-26/h5-8,10-17H,3-4,9,18H2,1-2H3,(H,29,30,32,33) KCMDGVOHTNAUCZ-UHFFFAOYSA-N 50044524 4-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-benzoic acid methyl ester::CHEMBL87073 Type-1 angiotensin II receptor Oryctolagus cuniculus 33 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044524 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044524&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956751 103975762 CHEMBL87073 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060449 CCCCc1nn(-c2cccc(OC)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O2/c1-3-4-12-25-30-34(21-8-7-9-22(17-21)36-2)27(35)33(25)18-19-13-15-20(16-14-19)23-10-5-6-11-24(23)26-28-31-32-29-26/h5-11,13-17H,3-4,12,18H2,1-2H3,(H,28,29,31,32) DPFCLXCSWUMENA-UHFFFAOYSA-N 50044511 5-Butyl-2-(3-methoxy-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86255 Type-1 angiotensin II receptor Oryctolagus cuniculus 15 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044511 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044511&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956744 103975749 CHEMBL86255 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060450 CCCc1nn(-c2ccccc2[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H22N8O3/c1-2-7-23-28-32(21-10-5-6-11-22(21)33(35)36)25(34)31(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24-26-29-30-27-24/h3-6,8-15H,2,7,16H2,1H3,(H,26,27,29,30) VGNQJXPQAWIFKN-UHFFFAOYSA-N 50044478 2-(2-Nitro-phenyl)-5-propyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87392 Type-1 angiotensin II receptor Oryctolagus cuniculus 9.5 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044478 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044478&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956771 103975716 CHEMBL87392 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060451 Clc1ccccc1-n1nc(C2CC2)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=O InChI=1S/C25H20ClN7O/c26-21-7-3-4-8-22(21)33-25(34)32(24(29-33)18-13-14-18)15-16-9-11-17(12-10-16)19-5-1-2-6-20(19)23-27-30-31-28-23/h1-12,18H,13-15H2,(H,27,28,30,31) FGBWSBBWLBJRQT-UHFFFAOYSA-N 50044528 2-(2-Chloro-phenyl)-5-cyclopropyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87890 Type-1 angiotensin II receptor Oryctolagus cuniculus 250 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044528 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044528&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956765 103975766 CHEMBL87890 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060452 CCCCc1nn(-c2ccc(CC)cc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H29N7O/c1-3-5-10-26-31-35(23-17-13-20(4-2)14-18-23)28(36)34(26)19-21-11-15-22(16-12-21)24-8-6-7-9-25(24)27-29-32-33-30-27/h6-9,11-18H,3-5,10,19H2,1-2H3,(H,29,30,32,33) RXKWCSFAWJEECE-UHFFFAOYSA-N 50044535 5-Butyl-2-(4-ethyl-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86613 Type-1 angiotensin II receptor Oryctolagus cuniculus 27 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044535 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044535&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956749 103975773 CHEMBL86613 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060453 CCCCc1nn(-c2ccccc2Cc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C33H31N7O/c1-2-3-17-31-36-40(30-16-10-7-13-27(30)22-24-11-5-4-6-12-24)33(41)39(31)23-25-18-20-26(21-19-25)28-14-8-9-15-29(28)32-34-37-38-35-32/h4-16,18-21H,2-3,17,22-23H2,1H3,(H,34,35,37,38) FCLZPSNCFZACFI-UHFFFAOYSA-N 50044482 2-(2-Benzyl-phenyl)-5-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL407827 Type-1 angiotensin II receptor Oryctolagus cuniculus 11 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044482 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044482&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956754 103975720 CHEMBL407827 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060454 CCCCc1nn(-c2cccc(Cl)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24ClN7O/c1-2-3-11-24-30-34(21-8-6-7-20(27)16-21)26(35)33(24)17-18-12-14-19(15-13-18)22-9-4-5-10-23(22)25-28-31-32-29-25/h4-10,12-16H,2-3,11,17H2,1H3,(H,28,29,31,32) UVRVYMFBLYRJGL-UHFFFAOYSA-N 50044481 5-Butyl-2-(3-chloro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87275 Type-1 angiotensin II receptor Oryctolagus cuniculus 120 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044481 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044481&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956742 103975719 CHEMBL87275 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060455 CCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H22ClN7O/c1-2-7-23-29-33(22-11-6-5-10-21(22)26)25(34)32(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24-27-30-31-28-24/h3-6,8-15H,2,7,16H2,1H3,(H,27,28,30,31) ZOWDYQLVMFRFBS-UHFFFAOYSA-N 50044483 2-(2-Chloro-phenyl)-5-propyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL315128 Type-1 angiotensin II receptor Oryctolagus cuniculus 14 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044483&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956766 103975721 CHEMBL315128 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060456 CCCCc1nn(-c2c(F)c(F)c(F)c(F)c2F)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |(-4.99,-15.76,;-3.49,-16.05,;-2.47,-14.9,;-.96,-15.21,;.04,-14.05,;-.29,-12.54,;1.04,-11.75,;1.17,-10.21,;2.58,-9.57,;3.83,-10.47,;2.71,-8.05,;4.11,-7.39,;1.45,-7.17,;1.58,-5.63,;.04,-7.81,;-1.22,-6.94,;-.09,-9.35,;-1.48,-9.99,;2.19,-12.77,;3.7,-12.43,;1.58,-14.19,;2.38,-15.51,;3.92,-15.5,;4.66,-14.15,;6.22,-14.13,;7,-15.44,;6.27,-16.79,;4.72,-16.81,;8.54,-15.41,;9.34,-16.73,;10.88,-16.69,;11.62,-15.35,;10.82,-14.03,;9.28,-14.06,;8.48,-12.75,;9.06,-11.34,;7.9,-10.33,;6.59,-11.13,;6.94,-12.62,)| InChI=1S/C26H20F5N7O/c1-2-3-8-18-34-38(24-22(30)20(28)19(27)21(29)23(24)31)26(39)37(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)25-32-35-36-33-25/h4-7,9-12H,2-3,8,13H2,1H3,(H,32,33,35,36) KKHIROLUJYOXNY-UHFFFAOYSA-N 50044485 5-Butyl-2-pentafluorophenyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL85541 Type-1 angiotensin II receptor Oryctolagus cuniculus 17 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044485 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044485&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956764 103975723 CHEMBL85541 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060457 CCCCc1nn(-c2ccccc2N(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H30N8O/c1-4-5-14-26-31-36(25-13-9-8-12-24(25)34(2)3)28(37)35(26)19-20-15-17-21(18-16-20)22-10-6-7-11-23(22)27-29-32-33-30-27/h6-13,15-18H,4-5,14,19H2,1-3H3,(H,29,30,32,33) DNYAPNXIBFDABQ-UHFFFAOYSA-N 50044493 5-Butyl-2-(2-dimethylamino-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL313025 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.2 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044493 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044493&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956761 103975731 CHEMBL313025 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060458 CCCCc1nn(-c2ccc(OC)cc2[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H26N8O4/c1-3-4-9-25-30-34(23-15-14-20(39-2)16-24(23)35(37)38)27(36)33(25)17-18-10-12-19(13-11-18)21-7-5-6-8-22(21)26-28-31-32-29-26/h5-8,10-16H,3-4,9,17H2,1-2H3,(H,28,29,31,32) QKRCKYPLONEPDX-UHFFFAOYSA-N 50044529 5-Butyl-2-(4-methoxy-2-nitro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL419483 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.740000 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044529 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044529&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956763 103975767 CHEMBL419483 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060459 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(NC(=O)c2ccccc2C(O)=O)cc1 InChI=1S/C27H25ClN4O4/c1-2-3-12-24-30-32(23-11-7-6-10-22(23)28)27(36)31(24)17-18-13-15-19(16-14-18)29-25(33)20-8-4-5-9-21(20)26(34)35/h4-11,13-16H,2-3,12,17H2,1H3,(H,29,33)(H,34,35) YDZQIBDFRLGABK-UHFFFAOYSA-N 50044536 N-{4-[3-Butyl-1-(2-chloro-phenyl)-5-oxo-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-phenyl}-phthalamic acid::CHEMBL85659 Type-1 angiotensin II receptor Oryctolagus cuniculus 570 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044536 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044536&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956773 103975774 CHEMBL85659 C06374 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060460 CCCCc1nn(-c2ccc(cc2)[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24N8O3/c1-2-3-8-24-29-33(20-13-15-21(16-14-20)34(36)37)26(35)32(24)17-18-9-11-19(12-10-18)22-6-4-5-7-23(22)25-27-30-31-28-25/h4-7,9-16H,2-3,8,17H2,1H3,(H,27,28,30,31) RXYHGDMFKBIBOR-UHFFFAOYSA-N 50044506 5-Butyl-2-(4-nitro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL84630 Type-1 angiotensin II receptor Oryctolagus cuniculus 80 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044506 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044506&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956747 103975744 CHEMBL84630 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060461 CCCCc1nn(-c2ccc(OC)cc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O2/c1-3-4-9-25-30-34(21-14-16-22(36-2)17-15-21)27(35)33(25)18-19-10-12-20(13-11-19)23-7-5-6-8-24(23)26-28-31-32-29-26/h5-8,10-17H,3-4,9,18H2,1-2H3,(H,28,29,31,32) VYPSRXIGJWWYNU-UHFFFAOYSA-N 50044501 5-Butyl-2-(4-methoxy-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL84627 Type-1 angiotensin II receptor Oryctolagus cuniculus 5 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044501 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044501&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956748 103975739 CHEMBL84627 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060462 CCCCc1nn(CC(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C22H22F3N7O/c1-2-3-8-19-28-32(14-22(23,24)25)21(33)31(19)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)20-26-29-30-27-20/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,26,27,29,30) JISRJBOVRKWXKT-UHFFFAOYSA-N 50044508 5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2,2,2-trifluoro-ethyl)-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87780 Type-1 angiotensin II receptor Oryctolagus cuniculus 76 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044508 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044508&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956782 103975746 CHEMBL87780 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060463 CCCCc1nn(C2CC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C23H25N7O/c1-2-3-8-21-26-30(18-13-14-18)23(31)29(21)15-16-9-11-17(12-10-16)19-6-4-5-7-20(19)22-24-27-28-25-22/h4-7,9-12,18H,2-3,8,13-15H2,1H3,(H,24,25,27,28) QOHPRLONBGDDDC-UHFFFAOYSA-N 50044484 5-Butyl-2-cyclopropyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87276 Type-1 angiotensin II receptor Oryctolagus cuniculus 100 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044484 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044484&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956777 103975722 CHEMBL87276 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060464 CCCCc1nn(-c2ccccc2C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O/c1-3-4-13-25-30-34(24-12-8-5-9-19(24)2)27(35)33(25)18-20-14-16-21(17-15-20)22-10-6-7-11-23(22)26-28-31-32-29-26/h5-12,14-17H,3-4,13,18H2,1-2H3,(H,28,29,31,32) NQNQDDDEXLGJHA-UHFFFAOYSA-N 50044533 5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-o-tolyl-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL83180 Type-1 angiotensin II receptor Oryctolagus cuniculus 4.1 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044533 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044533&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956738 103975771 CHEMBL83180 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060465 CCCCc1nn(-c2ccccc2C(O)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H25N7O3/c1-2-3-12-24-30-34(23-11-7-6-10-22(23)26(35)36)27(37)33(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-28-31-32-29-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,35,36)(H,28,29,31,32) MFYOOXJZGZRPSX-UHFFFAOYSA-N 50044492 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-benzoic acid::CHEMBL85704 Type-1 angiotensin II receptor Oryctolagus cuniculus 115 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044492 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044492&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956759 103975730 CHEMBL85704 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060466 CCCCc1nn(CC#N)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C22H22N8O/c1-2-3-8-20-26-30(14-13-23)22(31)29(20)15-16-9-11-17(12-10-16)18-6-4-5-7-19(18)21-24-27-28-25-21/h4-7,9-12H,2-3,8,14-15H2,1H3,(H,24,25,27,28) NBRAGACAUUXAOS-UHFFFAOYSA-N 50044495 {3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-acetonitrile::CHEMBL82920 Type-1 angiotensin II receptor Oryctolagus cuniculus 37 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044495 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044495&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956783 103975733 CHEMBL82920 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060467 CCCCc1nn(CC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C22H25N7O/c1-3-5-10-20-25-29(4-2)22(30)28(20)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)21-23-26-27-24-21/h6-9,11-14H,3-5,10,15H2,1-2H3,(H,23,24,26,27) KMYAXZQKKMWCBH-UHFFFAOYSA-N 50044343 5-Butyl-2-ethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86084 Type-1 angiotensin II receptor Oryctolagus cuniculus 10 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044343 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044343&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10222835 103975598 CHEMBL86084 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060468 CCCCc1nn(-c2cccc(c2)[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24N8O3/c1-2-3-11-24-29-33(20-7-6-8-21(16-20)34(36)37)26(35)32(24)17-18-12-14-19(15-13-18)22-9-4-5-10-23(22)25-27-30-31-28-25/h4-10,12-16H,2-3,11,17H2,1H3,(H,27,28,30,31) CXQZPZXQSZNCKT-UHFFFAOYSA-N 50044477 5-Butyl-2-(3-nitro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL420970 Type-1 angiotensin II receptor Oryctolagus cuniculus 43 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044477 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044477&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956743 103975715 CHEMBL420970 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060469 CCCCc1nn(CSc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7OS/c1-2-3-13-25-30-34(19-36-22-9-5-4-6-10-22)27(35)33(25)18-20-14-16-21(17-15-20)23-11-7-8-12-24(23)26-28-31-32-29-26/h4-12,14-17H,2-3,13,18-19H2,1H3,(H,28,29,31,32) HWOQZBXANOJRIA-UHFFFAOYSA-N 50044531 5-Butyl-2-phenylsulfanylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL314810 Type-1 angiotensin II receptor Oryctolagus cuniculus 16 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044531 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044531&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956806 103975769 CHEMBL314810 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060470 CCCCc1n[nH]c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C20H21N7O/c1-2-3-8-18-21-24-20(28)27(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)19-22-25-26-23-19/h4-7,9-12H,2-3,8,13H2,1H3,(H,24,28)(H,22,23,25,26) ZPPLJKNHXCIPHL-UHFFFAOYSA-N 50044350 5-Butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL69508 Type-1 angiotensin II receptor Oryctolagus cuniculus 60 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044350 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044350&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956775 103975605 CHEMBL69508 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060471 CCCCc1nn(-c2cccc(C)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O/c1-3-4-12-25-30-34(22-9-7-8-19(2)17-22)27(35)33(25)18-20-13-15-21(16-14-20)23-10-5-6-11-24(23)26-28-31-32-29-26/h5-11,13-17H,3-4,12,18H2,1-2H3,(H,28,29,31,32) GPZUZXGXTKUFKN-UHFFFAOYSA-N 50044487 5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-m-tolyl-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL315615 Type-1 angiotensin II receptor Oryctolagus cuniculus 18 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044487 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044487&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956741 103975725 CHEMBL315615 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060472 CCCCc1nn(-c2ccccc2OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O2/c1-3-4-13-25-30-34(23-11-7-8-12-24(23)36-2)27(35)33(25)18-19-14-16-20(17-15-19)21-9-5-6-10-22(21)26-28-31-32-29-26/h5-12,14-17H,3-4,13,18H2,1-2H3,(H,28,29,31,32) JJJKSURHGDYLPI-UHFFFAOYSA-N 50044498 5-Butyl-2-(2-methoxy-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL83248 Type-1 angiotensin II receptor Oryctolagus cuniculus 6.6 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044498&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956740 103975736 CHEMBL83248 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060473 CCCCc1nn(CC2CCCCC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H33N7O/c1-2-3-13-25-30-34(19-20-9-5-4-6-10-20)27(35)33(25)18-21-14-16-22(17-15-21)23-11-7-8-12-24(23)26-28-31-32-29-26/h7-8,11-12,14-17,20H,2-6,9-10,13,18-19H2,1H3,(H,28,29,31,32) BNJBKSRGCZLHDZ-UHFFFAOYSA-N 50044523 5-Butyl-2-cyclohexylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87239 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.9 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044523 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044523&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10298977 103975761 CHEMBL87239 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060474 CCCCc1nc(c(n1Cc2ccc(cc2)c3ccccc3c4[nH]nnn4)C(=O)O)Cl InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28) ZEUXAIYYDDCIRX-UHFFFAOYSA-N 50006909 2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::E 3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::EXP3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL907::Carboxylic Acid Metabolite (E-3174) Type-1 angiotensin II receptor Oryctolagus cuniculus 37 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006909&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search A1ATL 9BR7 108185 103920212 CHEMBL907 C15554 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060475 CCCCc1nn(-c2ccccc2N)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H26N8O/c1-2-3-12-24-30-34(23-11-7-6-10-22(23)27)26(35)33(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-28-31-32-29-25/h4-11,13-16H,2-3,12,17,27H2,1H3,(H,28,29,31,32) KRMMBTBPMGPMDD-UHFFFAOYSA-N 50044530 2-(2-Amino-phenyl)-5-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL424053 Type-1 angiotensin II receptor Oryctolagus cuniculus 100 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044530 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044530&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956760 103975768 CHEMBL424053 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060477 CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H29N7O/c1-3-4-12-26-31-35(19-22-9-7-8-20(2)17-22)28(36)34(26)18-21-13-15-23(16-14-21)24-10-5-6-11-25(24)27-29-32-33-30-27/h5-11,13-17H,3-4,12,18-19H2,1-2H3,(H,29,30,32,33) AJQSTGRQYVWHEA-UHFFFAOYSA-N 50044499 5-Butyl-2-(3-methyl-benzyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87129 Type-1 angiotensin II receptor Oryctolagus cuniculus 12 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044499&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956793 103975737 CHEMBL87129 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060478 CCCCc1nn(-c2ccc(Cl)cc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24ClN7O/c1-2-3-8-24-30-34(21-15-13-20(27)14-16-21)26(35)33(24)17-18-9-11-19(12-10-18)22-6-4-5-7-23(22)25-28-31-32-29-25/h4-7,9-16H,2-3,8,17H2,1H3,(H,28,29,31,32) CGTCYPGDABZOCB-UHFFFAOYSA-N 50044515 5-Butyl-2-(4-chloro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86440 Type-1 angiotensin II receptor Oryctolagus cuniculus 69 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044515 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044515&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956746 103975753 CHEMBL86440 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060482 CCCCc1nn(C(C)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H29N7O/c1-3-4-14-26-31-35(20(2)22-10-6-5-7-11-22)28(36)34(26)19-21-15-17-23(18-16-21)24-12-8-9-13-25(24)27-29-32-33-30-27/h5-13,15-18,20H,3-4,14,19H2,1-2H3,(H,29,30,32,33) VDBADUIMECELIQ-UHFFFAOYSA-N 50044514 5-Butyl-2-(1-phenyl-ethyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL85545 Type-1 angiotensin II receptor Oryctolagus cuniculus 4.9 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044514 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044514&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956794 103975752 CHEMBL85545 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060483 CCCCc1nn(C2CCCC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H29N7O/c1-2-3-12-23-28-32(20-8-4-5-9-20)25(33)31(23)17-18-13-15-19(16-14-18)21-10-6-7-11-22(21)24-26-29-30-27-24/h6-7,10-11,13-16,20H,2-5,8-9,12,17H2,1H3,(H,26,27,29,30) QIXCWNRRLORUTR-UHFFFAOYSA-N 50044491 5-Butyl-2-cyclopentyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86314 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.8 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044491 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044491&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956781 103975729 CHEMBL86314 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060484 CCCCc1nn(-c2ccc(C)cc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O/c1-3-4-9-25-30-34(22-16-10-19(2)11-17-22)27(35)33(25)18-20-12-14-21(15-13-20)23-7-5-6-8-24(23)26-28-31-32-29-26/h5-8,10-17H,3-4,9,18H2,1-2H3,(H,28,29,31,32) CNWVGLWMJZIYMP-UHFFFAOYSA-N 50044476 5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-p-tolyl-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86906 Type-1 angiotensin II receptor Oryctolagus cuniculus 16 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044476 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044476&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956745 103975714 CHEMBL86906 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060491 CCCCc1nn(CCCN(Cc2ccccc2)C(=O)OCc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C38H40N8O3/c1-2-3-19-35-41-46(25-12-24-44(26-29-13-6-4-7-14-29)38(48)49-28-31-15-8-5-9-16-31)37(47)45(35)27-30-20-22-32(23-21-30)33-17-10-11-18-34(33)36-39-42-43-40-36/h4-11,13-18,20-23H,2-3,12,19,24-28H2,1H3,(H,39,40,42,43) PULBYLRLAZMIDJ-UHFFFAOYSA-N 50044504 Benzyl-(3-{3-butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-propyl)-carbamic acid benzyl ester::CHEMBL313837 Type-1 angiotensin II receptor Oryctolagus cuniculus 30 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044504 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044504&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956809 103975742 CHEMBL313837 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060492 O=c1n(CCc2ccccc2)nc(C2CC2)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H25N7O/c35-27-33(26(22-14-15-22)30-34(27)17-16-19-6-2-1-3-7-19)18-20-10-12-21(13-11-20)23-8-4-5-9-24(23)25-28-31-32-29-25/h1-13,22H,14-18H2,(H,28,29,31,32) FJQWCQIXMQXZEC-UHFFFAOYSA-N 50044521 5-Cyclopropyl-2-phenethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL314333 Type-1 angiotensin II receptor Oryctolagus cuniculus 130 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044521 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044521&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956812 103975759 CHEMBL314333 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060495 CC(C)CCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H26ClN7O/c1-18(2)11-16-25-31-35(24-10-6-5-9-23(24)28)27(36)34(25)17-19-12-14-20(15-13-19)21-7-3-4-8-22(21)26-29-32-33-30-26/h3-10,12-15,18H,11,16-17H2,1-2H3,(H,29,30,32,33) HURXIVMCDOVSPL-UHFFFAOYSA-N 50044541 2-(2-Chloro-phenyl)-5-(3-methyl-butyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL315077 Type-1 angiotensin II receptor Oryctolagus cuniculus 16 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044541 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044541&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956768 103975779 CHEMBL315077 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060497 CCCCc1nn(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C21H23N7O/c1-3-4-9-19-24-27(2)21(29)28(19)14-15-10-12-16(13-11-15)17-7-5-6-8-18(17)20-22-25-26-23-20/h5-8,10-13H,3-4,9,14H2,1-2H3,(H,22,23,25,26) PZARVXWVGIUWJQ-UHFFFAOYSA-N 50044526 5-Butyl-2-methyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL313017 Type-1 angiotensin II receptor Oryctolagus cuniculus 70 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044526 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044526&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956776 103975764 CHEMBL313017 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060498 CCCCc1nn(C(C(C)C)C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H31N7O3/c1-5-6-11-22-29-33(23(17(2)3)25(34)36-4)26(35)32(22)16-18-12-14-19(15-13-18)20-9-7-8-10-21(20)24-27-30-31-28-24/h7-10,12-15,17,23H,5-6,11,16H2,1-4H3,(H,27,28,30,31) IXFBVYXKLIHYTD-UHFFFAOYSA-N 50044519 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-3-methyl-butyric acid methyl ester::CHEMBL88002 Type-1 angiotensin II receptor Oryctolagus cuniculus 52 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044519 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044519&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956789 103975757 CHEMBL88002 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060499 CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24ClN7O/c1-2-3-12-24-30-34(23-11-7-6-10-22(23)27)26(35)33(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-28-31-32-29-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,28,29,31,32) SKDWAGZYKUIFNE-UHFFFAOYSA-N 50044505 5-Butyl-2-(2-chloro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL18287 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.4 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044505 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044505&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9935106 103975743 CHEMBL18287 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060501 CCCCc1nn(Cc2cccc(c2)C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C29H29N7O3/c1-3-4-12-26-32-36(19-21-8-7-9-23(17-21)28(37)39-2)29(38)35(26)18-20-13-15-22(16-14-20)24-10-5-6-11-25(24)27-30-33-34-31-27/h5-11,13-17H,3-4,12,18-19H2,1-2H3,(H,30,31,33,34) APGBIAWZEONLFL-UHFFFAOYSA-N 50044542 3-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-ylmethyl}-benzoic acid methyl ester::CHEMBL83182 Type-1 angiotensin II receptor Oryctolagus cuniculus 110 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044542 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044542&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956796 103975780 CHEMBL83182 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060502 CCCCc1nn(Cc2ccc(cc2)C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C29H29N7O3/c1-3-4-9-26-32-36(19-21-12-16-23(17-13-21)28(37)39-2)29(38)35(26)18-20-10-14-22(15-11-20)24-7-5-6-8-25(24)27-30-33-34-31-27/h5-8,10-17H,3-4,9,18-19H2,1-2H3,(H,30,31,33,34) CTCYKZLAPSMDCH-UHFFFAOYSA-N 50044546 4-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-ylmethyl}-benzoic acid methyl ester::CHEMBL87885 Type-1 angiotensin II receptor Oryctolagus cuniculus 23 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044546 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044546&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956797 103975784 CHEMBL87885 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060506 CCCCc1nn(-c2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O3/c1-3-4-13-25-31-35(24-12-8-7-11-23(24)27(36)38-2)28(37)34(25)18-19-14-16-20(17-15-19)21-9-5-6-10-22(21)26-29-32-33-30-26/h5-12,14-17H,3-4,13,18H2,1-2H3,(H,29,30,32,33) WRSDIEZAVLTZHY-UHFFFAOYSA-N 50044507 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-benzoic acid methyl ester::CHEMBL314042 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.6 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044507 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044507&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956758 103975745 CHEMBL314042 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060507 CCCCc1nn(CC2CC2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H27N7O/c1-2-3-8-22-27-31(16-18-9-10-18)24(32)30(22)15-17-11-13-19(14-12-17)20-6-4-5-7-21(20)23-25-28-29-26-23/h4-7,11-14,18H,2-3,8-10,15-16H2,1H3,(H,25,26,28,29) ZPQUNKVDDNKQMS-UHFFFAOYSA-N 50044335 5-Butyl-2-cyclopropylmethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-cyclopropylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87669 Type-1 angiotensin II receptor Oryctolagus cuniculus 16 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044335 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044335&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14951062 103975590 CHEMBL87669 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060508 CCCCc1nn(c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)C InChI=1S/C24H29N7O/c1-5-6-11-21-27-31(24(2,3)4)23(32)30(21)16-17-12-14-18(15-13-17)19-9-7-8-10-20(19)22-25-28-29-26-22/h7-10,12-15H,5-6,11,16H2,1-4H3,(H,25,26,28,29) OAQWPJALNVUNJJ-UHFFFAOYSA-N 50044512 5-Butyl-2-tert-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL314436 Type-1 angiotensin II receptor Oryctolagus cuniculus 23 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044512 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044512&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10113613 103975750 CHEMBL314436 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060509 CCCCc1nn(-c2ccccc2F)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24FN7O/c1-2-3-12-24-30-34(23-11-7-6-10-22(23)27)26(35)33(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-28-31-32-29-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,28,29,31,32) UNZOQQZSMJFXOL-UHFFFAOYSA-N 50044490 5-Butyl-2-(2-fluoro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL313579 Type-1 angiotensin II receptor Oryctolagus cuniculus 7.7 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044490 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044490&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956755 103975728 CHEMBL313579 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060510 CCCCc1nn(CC(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H29N7O/c1-4-5-10-22-27-31(15-17(2)3)24(32)30(22)16-18-11-13-19(14-12-18)20-8-6-7-9-21(20)23-25-28-29-26-23/h6-9,11-14,17H,4-5,10,15-16H2,1-3H3,(H,25,26,28,29) JNZPWRFNTXNWAX-UHFFFAOYSA-N 50044540 5-Butyl-2-isobutyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87057 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.2 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044540 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044540&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956778 103975778 CHEMBL87057 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060511 CCCCc1nn(CCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C23H27N7O/c1-3-5-10-21-26-30(15-4-2)23(31)29(21)16-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-24-27-28-25-22/h6-9,11-14H,3-5,10,15-16H2,1-2H3,(H,24,25,27,28) RVAXYBUSVWMATJ-UHFFFAOYSA-N 50044346 5-Butyl-2-propyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-propyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL82797 Type-1 angiotensin II receptor Oryctolagus cuniculus 8.2 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044346 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044346&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10223724 103975601 CHEMBL82797 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060512 CCCCc1nn(C(C)CC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H29N7O/c1-4-6-11-22-27-31(17(3)5-2)24(32)30(22)16-18-12-14-19(15-13-18)20-9-7-8-10-21(20)23-25-28-29-26-23/h7-10,12-15,17H,4-6,11,16H2,1-3H3,(H,25,26,28,29) HZRZZXFVGPKWLK-UHFFFAOYSA-N 50044366 5-Butyl-2-sec-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-sec-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87964 Type-1 angiotensin II receptor Oryctolagus cuniculus 2.1 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044366 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044366&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9845644 103975621 CHEMBL87964 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060513 CCCCc1nn(Cc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H27N7O/c1-2-3-13-25-30-34(19-20-9-5-4-6-10-20)27(35)33(25)18-21-14-16-22(17-15-21)23-11-7-8-12-24(23)26-28-31-32-29-26/h4-12,14-17H,2-3,13,18-19H2,1H3,(H,28,29,31,32) CLIGTAMVAYBTCT-UHFFFAOYSA-N 50044344 2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::2-Benzyl-5-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL422593 Type-1 angiotensin II receptor Oryctolagus cuniculus 4.6 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044344 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044344&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10183373 103975599 CHEMBL422593 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060514 CCCCc1nn(C(C(O)=O)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O3/c1-2-3-13-24-31-35(25(27(36)37)21-9-5-4-6-10-21)28(38)34(24)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)26-29-32-33-30-26/h4-12,14-17,25H,2-3,13,18H2,1H3,(H,36,37)(H,29,30,32,33) HECADOVVTBUIIE-UHFFFAOYSA-N 50044520 {3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-phenyl-acetic acid::CHEMBL86143 Type-1 angiotensin II receptor Oryctolagus cuniculus 50 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044520 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044520&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956800 103975758 CHEMBL86143 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060515 CCCCc1nn(COc2ccc(Cl)cc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H26ClN7O2/c1-2-3-8-25-31-35(18-37-22-15-13-21(28)14-16-22)27(36)34(25)17-19-9-11-20(12-10-19)23-6-4-5-7-24(23)26-29-32-33-30-26/h4-7,9-16H,2-3,8,17-18H2,1H3,(H,29,30,32,33) XRNKTEGCXWMSBS-UHFFFAOYSA-N 50044517 5-Butyl-2-(4-chloro-phenoxymethyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87354 Type-1 angiotensin II receptor Oryctolagus cuniculus 50 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044517 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044517&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956805 103975755 CHEMBL87354 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060516 CCCCc1nc(c(n1Cc2ccc(cc2)c3ccccc3c4[nH]nnn4)C(=O)O)Cl InChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28) ZEUXAIYYDDCIRX-UHFFFAOYSA-N 50006909 2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::E 3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid (EXP3174)::EXP3174::2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL907::Carboxylic Acid Metabolite (E-3174) Type-1 angiotensin II receptor Oryctolagus cuniculus 6 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006909 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006909&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search A1ATL 9BR7 108185 103920212 CHEMBL907 C15554 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060517 CCCCc1nn(Cc2ccccc2C(O)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O3/c1-2-3-12-25-31-35(18-21-8-4-5-10-23(21)27(36)37)28(38)34(25)17-19-13-15-20(16-14-19)22-9-6-7-11-24(22)26-29-32-33-30-26/h4-11,13-16H,2-3,12,17-18H2,1H3,(H,36,37)(H,29,30,32,33) DCKMEXKESDPYIN-UHFFFAOYSA-N 50044497 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-ylmethyl}-benzoic acid::CHEMBL314590 Type-1 angiotensin II receptor Oryctolagus cuniculus 14 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044497 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044497&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956799 103975735 CHEMBL314590 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060518 CCCCc1nn(C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C21H23N7O/c1-3-4-9-19-24-27(2)21(29)28(19)14-15-10-12-16(13-11-15)17-7-5-6-8-18(17)20-22-25-26-23-20/h5-8,10-13H,3-4,9,14H2,1-2H3,(H,22,23,25,26) PZARVXWVGIUWJQ-UHFFFAOYSA-N 50044526 5-Butyl-2-methyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL313017 Type-1 angiotensin II receptor Oryctolagus cuniculus 90 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044526 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044526&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956776 103975764 CHEMBL313017 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060519 CCCCc1nn(Cc2ccccc2C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H29N7O/c1-3-4-13-26-31-35(19-23-10-6-5-9-20(23)2)28(36)34(26)18-21-14-16-22(17-15-21)24-11-7-8-12-25(24)27-29-32-33-30-27/h5-12,14-17H,3-4,13,18-19H2,1-2H3,(H,29,30,32,33) XUKGEBBKQLLORM-UHFFFAOYSA-N 50044522 5-Butyl-2-(2-methyl-benzyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL314447 Type-1 angiotensin II receptor Oryctolagus cuniculus 11 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044522 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044522&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956792 103975760 CHEMBL314447 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060520 CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) JGABCUJSSAEYFF-UHFFFAOYSA-N 50009714 CHEMBL191::{2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-3H-imidazol-4-yl}-methanol(DuP 753) Type-1 angiotensin II receptor Oryctolagus cuniculus 19 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009714 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009714&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 44330456 103922696 CHEMBL191 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060521 CCCCc1nn(-c2c(Cl)cccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |(2.26,-2.77,;3.37,-3.86,;4.83,-3.44,;5.95,-4.52,;7.42,-4.11,;7.96,-2.67,;9.5,-2.74,;10.45,-1.52,;9.89,-.1,;8.36,.12,;10.83,1.11,;12.36,.89,;12.93,-.54,;11.97,-1.76,;12.53,-3.19,;9.92,-4.22,;11.36,-4.76,;8.64,-5.07,;8.57,-6.61,;9.86,-7.42,;9.78,-8.96,;11.08,-9.79,;12.45,-9.08,;12.51,-7.54,;11.22,-6.72,;13.74,-9.9,;13.67,-11.45,;14.97,-12.27,;16.33,-11.55,;16.4,-10.01,;15.09,-9.2,;15.16,-7.66,;16.44,-6.79,;16.02,-5.32,;14.48,-5.25,;13.95,-6.7,)| InChI=1S/C26H23Cl2N7O/c1-2-3-11-23-31-35(24-21(27)9-6-10-22(24)28)26(36)34(23)16-17-12-14-18(15-13-17)19-7-4-5-8-20(19)25-29-32-33-30-25/h4-10,12-15H,2-3,11,16H2,1H3,(H,29,30,32,33) UUYKNTFLYAPMIE-UHFFFAOYSA-N 50044479 5-Butyl-2-(2,6-dichloro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL278741 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.8 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044479 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044479&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956762 103975717 CHEMBL278741 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060522 CCCCCc1nn(-c2ccccc2[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H26N8O3/c1-2-3-4-13-25-30-34(23-11-7-8-12-24(23)35(37)38)27(36)33(25)18-19-14-16-20(17-15-19)21-9-5-6-10-22(21)26-28-31-32-29-26/h5-12,14-17H,2-4,13,18H2,1H3,(H,28,29,31,32) QGMXISZCSJUNBU-UHFFFAOYSA-N 50044502 2-(2-Nitro-phenyl)-5-pentyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL312913 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.930000 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044502 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044502&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956772 103975740 CHEMBL312913 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060523 CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H24F3N7O/c1-2-3-12-24-33-37(23-11-7-6-10-22(23)27(28,29)30)26(38)36(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-31-34-35-32-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,31,32,34,35) DWXCNNUZEBMCMR-UHFFFAOYSA-N 50035431 5-Butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2-trifluoromethyl-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-(2-trifluoromethyl-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL19018 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.2 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035431 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035431&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956757 103943450 CHEMBL19018 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060524 CC(C)CCc1nn(CCc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C29H31N7O/c1-21(2)12-17-27-32-36(19-18-22-8-4-3-5-9-22)29(37)35(27)20-23-13-15-24(16-14-23)25-10-6-7-11-26(25)28-30-33-34-31-28/h3-11,13-16,21H,12,17-20H2,1-2H3,(H,30,31,33,34) DVCBBLFOWZAOLW-UHFFFAOYSA-N 50044537 5-(3-Methyl-butyl)-2-phenethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL83194 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.1 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044537 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044537&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956814 103975775 CHEMBL83194 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060525 CCCCc1nn(-c2ccc(F)cc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24FN7O/c1-2-3-8-24-30-34(21-15-13-20(27)14-16-21)26(35)33(24)17-18-9-11-19(12-10-18)22-6-4-5-7-23(22)25-28-31-32-29-25/h4-7,9-16H,2-3,8,17H2,1H3,(H,28,29,31,32) ZYRLMVWVLHAJAN-UHFFFAOYSA-N 50044475 5-Butyl-2-(4-fluoro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL85596 Type-1 angiotensin II receptor Oryctolagus cuniculus 21 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044475 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044475&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956750 103975713 CHEMBL85596 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060526 CCCCc1nn(CC(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C23H25N7O3/c1-3-4-9-20-26-30(15-21(31)33-2)23(32)29(20)14-16-10-12-17(13-11-16)18-7-5-6-8-19(18)22-24-27-28-25-22/h5-8,10-13H,3-4,9,14-15H2,1-2H3,(H,24,25,27,28) UIRFKGCJWQLGDF-UHFFFAOYSA-N 50044525 {3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-acetic acid methyl ester::CHEMBL314179 Type-1 angiotensin II receptor Oryctolagus cuniculus 17 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044525 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044525&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956784 103975763 CHEMBL314179 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060527 CCCCc1nn(C(C(=O)OC)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C29H29N7O3/c1-3-4-14-25-32-36(26(28(37)39-2)22-10-6-5-7-11-22)29(38)35(25)19-20-15-17-21(18-16-20)23-12-8-9-13-24(23)27-30-33-34-31-27/h5-13,15-18,26H,3-4,14,19H2,1-2H3,(H,30,31,33,34) WPQQQVTXYDQTAE-UHFFFAOYSA-N 50044539 {3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-phenyl-acetic acid methyl ester::CHEMBL87798 Type-1 angiotensin II receptor Oryctolagus cuniculus 12 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044539 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044539&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956798 103975777 CHEMBL87798 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060528 CCCCc1nn(C(C(O)=O)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O3/c1-2-3-13-24-31-35(25(27(36)37)21-9-5-4-6-10-21)28(38)34(24)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)26-29-32-33-30-26/h4-12,14-17,25H,2-3,13,18H2,1H3,(H,36,37)(H,29,30,32,33) HECADOVVTBUIIE-UHFFFAOYSA-N 50044520 {3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-phenyl-acetic acid::CHEMBL86143 Type-1 angiotensin II receptor Oryctolagus cuniculus 68 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044520 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044520&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956800 103975758 CHEMBL86143 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060529 CCCCc1nn(-c2ccccn2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H24N8O/c1-2-3-10-23-29-33(22-11-6-7-16-26-22)25(34)32(23)17-18-12-14-19(15-13-18)20-8-4-5-9-21(20)24-27-30-31-28-24/h4-9,11-16H,2-3,10,17H2,1H3,(H,27,28,30,31) ANFUBGXTPBQOPP-UHFFFAOYSA-N 50044532 5-Butyl-2-pyridin-2-yl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86741 Type-1 angiotensin II receptor Oryctolagus cuniculus 79 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044532 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044532&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956774 103975770 CHEMBL86741 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060530 CCCCc1nn(Cc2ccccc2C(O)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O3/c1-2-3-12-25-31-35(18-21-8-4-5-10-23(21)27(36)37)28(38)34(25)17-19-13-15-20(16-14-19)22-9-6-7-11-24(22)26-29-32-33-30-26/h4-11,13-16H,2-3,12,17-18H2,1H3,(H,36,37)(H,29,30,32,33) DCKMEXKESDPYIN-UHFFFAOYSA-N 50044497 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-ylmethyl}-benzoic acid::CHEMBL314590 Type-1 angiotensin II receptor Oryctolagus cuniculus 490 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044497 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044497&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956799 103975735 CHEMBL314590 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060531 CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28) JGABCUJSSAEYFF-UHFFFAOYSA-N 50009714 CHEMBL191::{2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-3H-imidazol-4-yl}-methanol(DuP 753) Type-1 angiotensin II receptor Oryctolagus cuniculus 50 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009714 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009714&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 44330456 103922696 CHEMBL191 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060532 CCCCc1nn(C(C)C(=O)NC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H28N8O2/c1-4-5-10-21-28-32(16(2)23(33)25-3)24(34)31(21)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-26-29-30-27-22/h6-9,11-14,16H,4-5,10,15H2,1-3H3,(H,25,33)(H,26,27,29,30) LWSXBIHXAZTDKP-UHFFFAOYSA-N 50044473 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-N-methyl-propionamide::CHEMBL87682 Type-1 angiotensin II receptor Oryctolagus cuniculus 95 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044473 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044473&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956785 103975711 CHEMBL87682 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060533 CCCCc1nn(C(C)CO)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C23H27N7O2/c1-3-4-9-21-26-30(16(2)15-31)23(32)29(21)14-17-10-12-18(13-11-17)19-7-5-6-8-20(19)22-24-27-28-25-22/h5-8,10-13,16,31H,3-4,9,14-15H2,1-2H3,(H,24,25,27,28) ODIKHAXFUUMWOA-UHFFFAOYSA-N 50044509 5-Butyl-2-(2-hydroxy-1-methyl-ethyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL315012 Type-1 angiotensin II receptor Oryctolagus cuniculus 24 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044509 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044509&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956786 103975747 CHEMBL315012 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060534 CCCCc1nn(C(C)C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H27N7O3/c1-4-5-10-21-27-31(16(2)23(32)34-3)24(33)30(21)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)22-25-28-29-26-22/h6-9,11-14,16H,4-5,10,15H2,1-3H3,(H,25,26,28,29) MHHPOVHKEOVCLM-UHFFFAOYSA-N 50044516 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-propionic acid methyl ester::CHEMBL87363 Type-1 angiotensin II receptor Oryctolagus cuniculus 11 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044516 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044516&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956787 103975754 CHEMBL87363 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060535 CCCCc1nn(CC(=O)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O2/c1-2-3-13-26-31-35(19-25(36)22-9-5-4-6-10-22)28(37)34(26)18-20-14-16-21(17-15-20)23-11-7-8-12-24(23)27-29-32-33-30-27/h4-12,14-17H,2-3,13,18-19H2,1H3,(H,29,30,32,33) SLLKEOIZGYGZBQ-UHFFFAOYSA-N 50044348 5-Butyl-2-(2-oxo-2-phenyl-ethyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-(2-oxo-2-phenyl-ethyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87942 Type-1 angiotensin II receptor Oryctolagus cuniculus 12 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044348 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044348&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14951059 103975603 CHEMBL87942 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060536 CCCCc1nn(C(C)C(O)=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C23H25N7O3/c1-3-4-9-20-26-30(15(2)22(31)32)23(33)29(20)14-16-10-12-17(13-11-16)18-7-5-6-8-19(18)21-24-27-28-25-21/h5-8,10-13,15H,3-4,9,14H2,1-2H3,(H,31,32)(H,24,25,27,28) AXEIUUWKJNJHAE-UHFFFAOYSA-N 50044494 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-propionic acid::CHEMBL315469 Type-1 angiotensin II receptor Oryctolagus cuniculus 26 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044494 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044494&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956788 103975732 CHEMBL315469 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060537 CCCCc1nn(Cc2ccc3ccccc3c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C31H29N7O/c1-2-3-12-29-34-38(21-23-15-16-24-8-4-5-9-26(24)19-23)31(39)37(29)20-22-13-17-25(18-14-22)27-10-6-7-11-28(27)30-32-35-36-33-30/h4-11,13-19H,2-3,12,20-21H2,1H3,(H,32,33,35,36) ASSQJXCGYVVNGG-UHFFFAOYSA-N 50044362 5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-naphthalen-2-ylmethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86986 Type-1 angiotensin II receptor Oryctolagus cuniculus 27 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044362 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044362&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956803 103975617 CHEMBL86986 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060538 CCCCc1nn(-c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H25N7O/c1-2-3-13-24-29-33(21-9-5-4-6-10-21)26(34)32(24)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)25-27-30-31-28-25/h4-12,14-17H,2-3,13,18H2,1H3,(H,27,28,30,31) KYTVRGJDSRRIEG-UHFFFAOYSA-N 50044354 5-Butyl-2-phenyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL85876 Type-1 angiotensin II receptor Oryctolagus cuniculus 22 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044354 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044354&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10275744 103975609 CHEMBL85876 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060539 [O-][N+](=O)c1ccccc1-n1nc(C2CC2)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=O InChI=1S/C25H20N8O3/c34-25-31(24(18-13-14-18)28-32(25)21-7-3-4-8-22(21)33(35)36)15-16-9-11-17(12-10-16)19-5-1-2-6-20(19)23-26-29-30-27-23/h1-12,18H,13-15H2,(H,26,27,29,30) BPWHGUFERPAUEX-UHFFFAOYSA-N 50044527 5-Cyclopropyl-2-(2-nitro-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL86853 Type-1 angiotensin II receptor Oryctolagus cuniculus 95 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044527 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044527&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956770 103975765 CHEMBL86853 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060540 CCCCc1nn(-c2ccccc2-c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C32H29N7O/c1-2-3-17-30-35-39(29-16-10-9-14-27(29)24-11-5-4-6-12-24)32(40)38(30)22-23-18-20-25(21-19-23)26-13-7-8-15-28(26)31-33-36-37-34-31/h4-16,18-21H,2-3,17,22H2,1H3,(H,33,34,36,37) HAIVKSHDQLOZEG-UHFFFAOYSA-N 50044534 2-Biphenyl-2-yl-5-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL315776 Type-1 angiotensin II receptor Oryctolagus cuniculus 3.6 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044534 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044534&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956753 103975772 CHEMBL315776 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060541 CCCCc1nn(C(C)CC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H29N7O/c1-4-6-11-22-27-31(17(3)5-2)24(32)30(22)16-18-12-14-19(15-13-18)20-9-7-8-10-21(20)23-25-28-29-26-23/h7-10,12-15,17H,4-6,11,16H2,1-3H3,(H,25,26,28,29) HZRZZXFVGPKWLK-UHFFFAOYSA-N 50044366 5-Butyl-2-sec-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-sec-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87964 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.8 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044366 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044366&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 9845644 103975621 CHEMBL87964 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060542 CCCCc1nn(-c2ccccc2C(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C29H31N7O/c1-4-5-14-27-32-36(26-13-9-8-10-23(26)20(2)3)29(37)35(27)19-21-15-17-22(18-16-21)24-11-6-7-12-25(24)28-30-33-34-31-28/h6-13,15-18,20H,4-5,14,19H2,1-3H3,(H,30,31,33,34) GBHDXMPLOOJUQY-UHFFFAOYSA-N 50044543 5-Butyl-2-(2-isopropyl-phenyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-(2-isopropyl-phenyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL431411 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.4 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044543 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044543&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320012 103975781 CHEMBL431411 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060543 CCCCc1nn(Cc2c(F)c(F)c(F)c(F)c2F)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H22F5N7O/c1-2-3-8-20-35-39(14-19-21(28)23(30)25(32)24(31)22(19)29)27(40)38(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)26-33-36-37-34-26/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,33,34,36,37) MYHNQMLUZIOCBC-UHFFFAOYSA-N 50044544 5-Butyl-2-pentafluorophenylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL85765 Type-1 angiotensin II receptor Oryctolagus cuniculus 32 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044544 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044544&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956801 103975782 CHEMBL85765 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060544 CCCc1nn(-c2ccccc2[N+]([O-])=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H22N8O3/c1-2-7-23-28-32(21-10-5-6-11-22(21)33(35)36)25(34)31(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24-26-29-30-27-24/h3-6,8-15H,2,7,16H2,1H3,(H,26,27,29,30) VGNQJXPQAWIFKN-UHFFFAOYSA-N 50044478 2-(2-Nitro-phenyl)-5-propyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87392 Type-1 angiotensin II receptor Oryctolagus cuniculus 21 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044478 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044478&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956771 103975716 CHEMBL87392 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060545 CCCCc1nn(Cc2ccccc2C(=O)OC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C29H29N7O3/c1-3-4-13-26-32-36(19-22-9-5-6-11-24(22)28(37)39-2)29(38)35(26)18-20-14-16-21(17-15-20)23-10-7-8-12-25(23)27-30-33-34-31-27/h5-12,14-17H,3-4,13,18-19H2,1-2H3,(H,30,31,33,34) NVLJXTCTDPLEBQ-UHFFFAOYSA-N 50044474 2-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-ylmethyl}-benzoic acid methyl ester::CHEMBL312921 Type-1 angiotensin II receptor Oryctolagus cuniculus 11 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044474 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044474&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 19939367 103975712 CHEMBL312921 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060546 CCCCc1nn(C2CCCC2O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H29N7O2/c1-2-3-11-23-28-32(21-9-6-10-22(21)33)25(34)31(23)16-17-12-14-18(15-13-17)19-7-4-5-8-20(19)24-26-29-30-27-24/h4-5,7-8,12-15,21-22,33H,2-3,6,9-11,16H2,1H3,(H,26,27,29,30) IGJPOVOJDKIXNG-UHFFFAOYSA-N 50044489 5-Butyl-2-(2-hydroxy-cyclopentyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87341 Type-1 angiotensin II receptor Oryctolagus cuniculus 12 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044489 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044489&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956791 103975727 CHEMBL87341 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060547 CCCCc1nn(-c2ccccc2Br)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C26H24BrN7O/c1-2-3-12-24-30-34(23-11-7-6-10-22(23)27)26(35)33(24)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)25-28-31-32-29-25/h4-11,13-16H,2-3,12,17H2,1H3,(H,28,29,31,32) PSIGSVWJZPKUKH-UHFFFAOYSA-N 50044488 2-(2-Bromo-phenyl)-5-butyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87513 Type-1 angiotensin II receptor Oryctolagus cuniculus 2 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044488 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044488&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956756 103975726 CHEMBL87513 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060548 CCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C25H22ClN7O/c1-2-7-23-29-33(22-11-6-5-10-21(22)26)25(34)32(23)16-17-12-14-18(15-13-17)19-8-3-4-9-20(19)24-27-30-31-28-24/h3-6,8-15H,2,7,16H2,1H3,(H,27,28,30,31) ZOWDYQLVMFRFBS-UHFFFAOYSA-N 50044483 2-(2-Chloro-phenyl)-5-propyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL315128 Type-1 angiotensin II receptor Oryctolagus cuniculus 20 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044483 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044483&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956766 103975721 CHEMBL315128 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060549 CCCCc1nn(CCCN(C)C(=O)OCc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C32H36N8O3/c1-3-4-15-29-35-40(21-10-20-38(2)32(42)43-23-25-11-6-5-7-12-25)31(41)39(29)22-24-16-18-26(19-17-24)27-13-8-9-14-28(27)30-33-36-37-34-30/h5-9,11-14,16-19H,3-4,10,15,20-23H2,1-2H3,(H,33,34,36,37) WDGGVTPCTUENAR-UHFFFAOYSA-N 50044510 (3-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-propyl)-methyl-carbamic acid benzyl ester::CHEMBL87957 Type-1 angiotensin II receptor Oryctolagus cuniculus 60 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044510 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044510&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956808 103975748 CHEMBL87957 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060550 CCCCc1nn(CCCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H29N7O/c1-3-5-11-22-27-31(16-6-4-2)24(32)30(22)17-18-12-14-19(15-13-18)20-9-7-8-10-21(20)23-25-28-29-26-23/h7-10,12-15H,3-6,11,16-17H2,1-2H3,(H,25,26,28,29) STODEQQYGGTXOS-UHFFFAOYSA-N 50044355 2,5-Dibutyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one(SC-15316)::2,5-Dibutyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-[1,2,4]triazolidin-3-one::2,5-Dibutyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87778 Type-1 angiotensin II receptor Oryctolagus cuniculus 1.8 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044355&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 131654 103975610 CHEMBL87778 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060551 CCCCc1nn(CCCC)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C24H29N7O/c1-3-5-11-22-27-31(16-6-4-2)24(32)30(22)17-18-12-14-19(15-13-18)20-9-7-8-10-21(20)23-25-28-29-26-23/h7-10,12-15H,3-6,11,16-17H2,1-2H3,(H,25,26,28,29) STODEQQYGGTXOS-UHFFFAOYSA-N 50044355 2,5-Dibutyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one(SC-15316)::2,5-Dibutyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-[1,2,4]triazolidin-3-one::2,5-Dibutyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87778 Type-1 angiotensin II receptor Oryctolagus cuniculus 5 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044355 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044355&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 131654 103975610 CHEMBL87778 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060552 CCCCc1nn(CCCOC(=O)N(C)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C31H34N8O3/c1-3-4-15-28-34-39(20-10-21-42-31(41)37(2)25-11-6-5-7-12-25)30(40)38(28)22-23-16-18-24(19-17-23)26-13-8-9-14-27(26)29-32-35-36-33-29/h5-9,11-14,16-19H,3-4,10,15,20-22H2,1-2H3,(H,32,33,35,36) ZWAXWUPHYATLOF-UHFFFAOYSA-N 50044480 Methyl-phenyl-carbamic acid 3-{3-butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-yl}-propyl ester::CHEMBL313435 Type-1 angiotensin II receptor Oryctolagus cuniculus 7.4 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044480 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044480&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956807 103975718 CHEMBL313435 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060553 CCCCc1nn(CCCc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C29H31N7O/c1-2-3-15-27-32-36(20-9-12-22-10-5-4-6-11-22)29(37)35(27)21-23-16-18-24(19-17-23)25-13-7-8-14-26(25)28-30-33-34-31-28/h4-8,10-11,13-14,16-19H,2-3,9,12,15,20-21H2,1H3,(H,30,31,33,34) CSQXFYGNSGJKRX-UHFFFAOYSA-N 50044364 5-Butyl-2-(3-phenyl-propyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-(3-phenyl-propyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL313222 Type-1 angiotensin II receptor Oryctolagus cuniculus 11 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044364 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044364&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956804 103975619 CHEMBL313222 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060554 CCCCc1nn(CCc2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H29N7O/c1-2-3-13-26-31-35(19-18-21-9-5-4-6-10-21)28(36)34(26)20-22-14-16-23(17-15-22)24-11-7-8-12-25(24)27-29-32-33-30-27/h4-12,14-17H,2-3,13,18-20H2,1H3,(H,29,30,32,33) KOGDEEKMGBZZPT-UHFFFAOYSA-N 50044356 5-Butyl-2-phenethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-phenethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL313371 Type-1 angiotensin II receptor Oryctolagus cuniculus 0.900000 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044356 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044356&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 10140613 103975611 CHEMBL313371 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060555 CCCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C27H26ClN7O/c1-2-3-4-13-25-31-35(24-12-8-7-11-23(24)28)27(36)34(25)18-19-14-16-20(17-15-19)21-9-5-6-10-22(21)26-29-32-33-30-26/h5-12,14-17H,2-4,13,18H2,1H3,(H,29,30,32,33) KZTAUKJEFUHABC-UHFFFAOYSA-N 50044486 2-(2-Chloro-phenyl)-5-pentyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL316052 Type-1 angiotensin II receptor Oryctolagus cuniculus 5.7 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044486 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044486&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956769 103975724 CHEMBL316052 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060556 O=c1n(CCc2ccccc2)nc(CC2CC2)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C28H27N7O/c36-28-34(26(18-21-10-11-21)31-35(28)17-16-20-6-2-1-3-7-20)19-22-12-14-23(15-13-22)24-8-4-5-9-25(24)27-29-32-33-30-27/h1-9,12-15,21H,10-11,16-19H2,(H,29,30,32,33) CDKBFMTUCHYJMM-UHFFFAOYSA-N 50044545 5-Cyclopropylmethyl-2-phenethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87330 Type-1 angiotensin II receptor Oryctolagus cuniculus 14 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044545 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044545&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956813 103975783 CHEMBL87330 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060557 Clc1ccccc1-n1nc(CC2CC2)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=O InChI=1S/C26H22ClN7O/c27-22-7-3-4-8-23(22)34-26(35)33(24(30-34)15-17-9-10-17)16-18-11-13-19(14-12-18)20-5-1-2-6-21(20)25-28-31-32-29-25/h1-8,11-14,17H,9-10,15-16H2,(H,28,29,31,32) GJFAQCNDSQVRNY-UHFFFAOYSA-N 50044538 2-(2-Chloro-phenyl)-5-cyclopropylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87650 Type-1 angiotensin II receptor Oryctolagus cuniculus 27 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044538 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044538&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956767 103975776 CHEMBL87650 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060558 CCCCc1nn(Cc2ccc(cc2)-c2ccccc2C#N)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C34H30N8O/c1-2-3-12-32-38-42(23-25-15-17-26(18-16-25)29-9-5-4-8-28(29)21-35)34(43)41(32)22-24-13-19-27(20-14-24)30-10-6-7-11-31(30)33-36-39-40-37-33/h4-11,13-20H,2-3,12,22-23H2,1H3,(H,36,37,39,40) VHCWVAJMOZPCBD-UHFFFAOYSA-N 50044500 4'-{3-Butyl-5-oxo-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4,5-dihydro-[1,2,4]triazol-1-ylmethyl}-biphenyl-2-carbonitrile::CHEMBL86232 Type-1 angiotensin II receptor Oryctolagus cuniculus 680 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044500 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044500&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956810 103975738 CHEMBL86232 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060559 CCCCc1nn(Cc2cccc3ccccc23)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C31H29N7O/c1-2-3-15-29-34-38(21-25-11-8-10-23-9-4-5-12-26(23)25)31(39)37(29)20-22-16-18-24(19-17-22)27-13-6-7-14-28(27)30-32-35-36-33-30/h4-14,16-19H,2-3,15,20-21H2,1H3,(H,32,33,35,36) FLXRPKSXQBOIGE-UHFFFAOYSA-N 50044337 5-Butyl-2-naphthalen-1-ylmethyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::5-Butyl-2-naphthalen-1-ylmethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87184 Type-1 angiotensin II receptor Oryctolagus cuniculus 33 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044337 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044337&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 14956802 103975592 CHEMBL87184 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976 50060560 CCCCc1nn(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 InChI=1S/C34H31N11O/c1-2-3-12-31-39-45(22-24-15-19-26(20-16-24)28-9-5-7-11-30(28)33-37-42-43-38-33)34(46)44(31)21-23-13-17-25(18-14-23)27-8-4-6-10-29(27)32-35-40-41-36-32/h4-11,13-20H,2-3,12,21-22H2,1H3,(H,35,36,40,41)(H,37,38,42,43) QHLIHOMQXOVLRD-UHFFFAOYSA-N 50044496 5-Butyl-2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL313696 Type-1 angiotensin II receptor Oryctolagus cuniculus 10 ChEMBL 10.1021/jm00069a015 10.7270/Q2KP817C 8355255 Chang, LL; Ashton, WT; Flanagan, KL; Strelitz, RA; MacCoss, M; Greenlee, WJ; Chang, RS; Lotti, VJ; Faust, KA; Chen, TB 9/23/1993 11/10/2009 Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044496 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000266&target=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044496&enzyme=Type-1+angiotensin+II+receptor&column=ki&startPg=0&Increment=50&submit=Search 19939399 103975734 CHEMBL313696 1 MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE 6OS2,6OS1,6OS0,6DO1 Type-1 angiotensin II receptor AGTR1_RABIT P34976