BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Date of publication Date in BindingDB Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence 1 PDB ID(s) of Target Chain 1 UniProt (SwissProt) Recommended Name of Target Chain 1 UniProt (SwissProt) Entry Name of Target Chain 1 UniProt (SwissProt) Primary ID of Target Chain 1 UniProt (SwissProt) Secondary ID(s) of Target Chain 1 UniProt (SwissProt) Alternative ID(s) of Target Chain 1 UniProt (TrEMBL) Submitted Name of Target Chain 1 UniProt (TrEMBL) Entry Name of Target Chain 1 UniProt (TrEMBL) Primary ID of Target Chain 1 UniProt (TrEMBL) Secondary ID(s) of Target Chain 1 UniProt (TrEMBL) Alternative ID(s) of Target Chain 1 BindingDB Target Chain Sequence 2 PDB ID(s) of Target Chain 2 UniProt (SwissProt) Recommended Name of Target Chain 2 UniProt (SwissProt) Entry Name of Target Chain 2 UniProt (SwissProt) Primary ID of Target Chain 2 UniProt (SwissProt) Secondary ID(s) of Target Chain 2 UniProt (SwissProt) Alternative ID(s) of Target Chain 2 UniProt (TrEMBL) Submitted Name of Target Chain 2 UniProt (TrEMBL) Entry Name of Target Chain 2 UniProt (TrEMBL) Primary ID of Target Chain 2 UniProt (TrEMBL) Secondary ID(s) of Target Chain 2 UniProt (TrEMBL) Alternative ID(s) of Target Chain 2 BindingDB Target Chain Sequence 3 PDB ID(s) of Target Chain 3 UniProt (SwissProt) Recommended Name of Target Chain 3 UniProt (SwissProt) Entry Name of Target Chain 3 UniProt (SwissProt) Primary ID of Target Chain 3 UniProt (SwissProt) Secondary ID(s) of Target Chain 3 UniProt (SwissProt) Alternative ID(s) of Target Chain 3 UniProt (TrEMBL) Submitted Name of Target Chain 3 UniProt (TrEMBL) Entry Name of Target Chain 3 UniProt (TrEMBL) Primary ID of Target Chain 3 UniProt (TrEMBL) Secondary ID(s) of Target Chain 3 UniProt (TrEMBL) Alternative ID(s) of Target Chain 3 BindingDB Target Chain Sequence 4 PDB ID(s) of Target Chain 4 UniProt (SwissProt) Recommended Name of Target Chain 4 UniProt (SwissProt) Entry Name of Target Chain 4 UniProt (SwissProt) Primary ID of Target Chain 4 UniProt (SwissProt) Secondary ID(s) of Target Chain 4 UniProt (SwissProt) Alternative ID(s) of Target Chain 4 UniProt (TrEMBL) Submitted Name of Target Chain 4 UniProt (TrEMBL) Entry Name of Target Chain 4 UniProt (TrEMBL) Primary ID of Target Chain 4 UniProt (TrEMBL) Secondary ID(s) of Target Chain 4 UniProt (TrEMBL) Alternative ID(s) of Target Chain 4 BindingDB Target Chain Sequence 5 PDB ID(s) of Target Chain 5 UniProt (SwissProt) Recommended Name of Target Chain 5 UniProt (SwissProt) Entry Name of Target Chain 5 UniProt (SwissProt) Primary ID of Target Chain 5 UniProt (SwissProt) Secondary ID(s) of Target Chain 5 UniProt (SwissProt) Alternative ID(s) of Target Chain 5 UniProt (TrEMBL) Submitted Name of Target Chain 5 UniProt (TrEMBL) Entry Name of Target Chain 5 UniProt (TrEMBL) Primary ID of Target Chain 5 UniProt (TrEMBL) Secondary ID(s) of Target Chain 5 UniProt (TrEMBL) Alternative ID(s) of Target Chain 5 BindingDB Target Chain Sequence 6 PDB ID(s) of Target Chain 6 UniProt (SwissProt) Recommended Name of Target Chain 6 UniProt (SwissProt) Entry Name of Target Chain 6 UniProt (SwissProt) Primary ID of Target Chain 6 UniProt (SwissProt) Secondary ID(s) of Target Chain 6 UniProt (SwissProt) Alternative ID(s) of Target Chain 6 UniProt (TrEMBL) Submitted Name of Target Chain 6 UniProt (TrEMBL) Entry Name of Target Chain 6 UniProt (TrEMBL) Primary ID of Target Chain 6 UniProt (TrEMBL) Secondary ID(s) of Target Chain 6 UniProt (TrEMBL) Alternative ID(s) of Target Chain 6 BindingDB Target Chain Sequence 7 PDB ID(s) of Target Chain 7 UniProt (SwissProt) Recommended Name of Target Chain 7 UniProt (SwissProt) Entry Name of Target Chain 7 UniProt (SwissProt) Primary ID of Target Chain 7 UniProt (SwissProt) Secondary ID(s) of Target Chain 7 UniProt (SwissProt) Alternative ID(s) of Target Chain 7 UniProt (TrEMBL) Submitted Name of Target Chain 7 UniProt (TrEMBL) Entry Name of Target Chain 7 UniProt (TrEMBL) Primary ID of Target Chain 7 UniProt (TrEMBL) Secondary ID(s) of Target Chain 7 UniProt (TrEMBL) Alternative ID(s) of Target Chain 7 BindingDB Target Chain Sequence 8 PDB ID(s) of Target Chain 8 UniProt (SwissProt) Recommended Name of Target Chain 8 UniProt (SwissProt) Entry Name of Target Chain 8 UniProt (SwissProt) Primary ID of Target Chain 8 UniProt (SwissProt) Secondary ID(s) of Target Chain 8 UniProt (SwissProt) Alternative ID(s) of Target Chain 8 UniProt (TrEMBL) Submitted Name of Target Chain 8 UniProt (TrEMBL) Entry Name of Target Chain 8 UniProt (TrEMBL) Primary ID of Target Chain 8 UniProt (TrEMBL) Secondary ID(s) of Target Chain 8 UniProt (TrEMBL) Alternative ID(s) of Target Chain 8 BindingDB Target Chain Sequence 9 PDB ID(s) of Target Chain 9 UniProt (SwissProt) Recommended Name of Target Chain 9 UniProt (SwissProt) Entry Name of Target Chain 9 UniProt (SwissProt) Primary ID of Target Chain 9 UniProt (SwissProt) Secondary ID(s) of Target Chain 9 UniProt (SwissProt) Alternative ID(s) of Target Chain 9 UniProt (TrEMBL) Submitted Name of Target Chain 9 UniProt (TrEMBL) Entry Name of Target Chain 9 UniProt (TrEMBL) Primary ID of Target Chain 9 UniProt (TrEMBL) Secondary ID(s) of Target Chain 9 UniProt (TrEMBL) Alternative ID(s) of Target Chain 9 BindingDB Target Chain Sequence 10 PDB ID(s) of Target Chain 10 UniProt (SwissProt) Recommended Name of Target Chain 10 UniProt (SwissProt) Entry Name of Target Chain 10 UniProt (SwissProt) Primary ID of Target Chain 10 UniProt (SwissProt) Secondary ID(s) of Target Chain 10 UniProt (SwissProt) Alternative ID(s) of Target Chain 10 UniProt (TrEMBL) Submitted Name of Target Chain 10 UniProt (TrEMBL) Entry Name of Target Chain 10 UniProt (TrEMBL) Primary ID of Target Chain 10 UniProt (TrEMBL) Secondary ID(s) of Target Chain 10 UniProt (TrEMBL) Alternative ID(s) of Target Chain 10 BindingDB Target Chain Sequence 11 PDB ID(s) of Target Chain 11 UniProt (SwissProt) Recommended Name of Target Chain 11 UniProt (SwissProt) Entry Name of Target Chain 11 UniProt (SwissProt) Primary ID of Target Chain 11 UniProt (SwissProt) Secondary ID(s) of Target Chain 11 UniProt (SwissProt) Alternative ID(s) of Target Chain 11 UniProt (TrEMBL) Submitted Name of Target Chain 11 UniProt (TrEMBL) Entry Name of Target Chain 11 UniProt (TrEMBL) Primary ID of Target Chain 11 UniProt (TrEMBL) Secondary ID(s) of Target Chain 11 UniProt (TrEMBL) Alternative ID(s) of Target Chain 11 BindingDB Target Chain Sequence 12 PDB ID(s) of Target Chain 12 UniProt (SwissProt) Recommended Name of Target Chain 12 UniProt (SwissProt) Entry Name of Target Chain 12 UniProt (SwissProt) Primary ID of Target Chain 12 UniProt (SwissProt) Secondary ID(s) of Target Chain 12 UniProt (SwissProt) Alternative ID(s) of Target Chain 12 UniProt (TrEMBL) Submitted Name of Target Chain 12 UniProt (TrEMBL) Entry Name of Target Chain 12 UniProt (TrEMBL) Primary ID of Target Chain 12 UniProt (TrEMBL) Secondary ID(s) of Target Chain 12 UniProt (TrEMBL) Alternative ID(s) of Target Chain 12 BindingDB Target Chain Sequence 13 PDB ID(s) of Target Chain 13 UniProt (SwissProt) Recommended Name of Target Chain 13 UniProt (SwissProt) Entry Name of Target Chain 13 UniProt (SwissProt) Primary ID of Target Chain 13 UniProt (SwissProt) Secondary ID(s) of Target Chain 13 UniProt (SwissProt) Alternative ID(s) of Target Chain 13 UniProt (TrEMBL) Submitted Name of Target Chain 13 UniProt (TrEMBL) Entry Name of Target Chain 13 UniProt (TrEMBL) Primary ID of Target Chain 13 UniProt (TrEMBL) Secondary ID(s) of Target Chain 13 UniProt (TrEMBL) Alternative ID(s) of Target Chain 13 BindingDB Target Chain Sequence 14 PDB ID(s) of Target Chain 14 UniProt (SwissProt) Recommended Name of Target Chain 14 UniProt (SwissProt) Entry Name of Target Chain 14 UniProt (SwissProt) Primary ID of Target Chain 14 UniProt (SwissProt) Secondary ID(s) of Target Chain 14 UniProt (SwissProt) Alternative ID(s) of Target Chain 14 UniProt (TrEMBL) Submitted Name of Target Chain 14 UniProt (TrEMBL) Entry Name of Target Chain 14 UniProt (TrEMBL) Primary ID of Target Chain 14 UniProt (TrEMBL) Secondary ID(s) of Target Chain 14 UniProt (TrEMBL) Alternative ID(s) of Target Chain 14 BindingDB Target Chain Sequence 15 PDB ID(s) of Target Chain 15 UniProt (SwissProt) Recommended Name of Target Chain 15 UniProt (SwissProt) Entry Name of Target Chain 15 UniProt (SwissProt) Primary ID of Target Chain 15 UniProt (SwissProt) Secondary ID(s) of Target Chain 15 UniProt (SwissProt) Alternative ID(s) of Target Chain 15 UniProt (TrEMBL) Submitted Name of Target Chain 15 UniProt (TrEMBL) Entry Name of Target Chain 15 UniProt (TrEMBL) Primary ID of Target Chain 15 UniProt (TrEMBL) Secondary ID(s) of Target Chain 15 UniProt (TrEMBL) Alternative ID(s) of Target Chain 15 BindingDB Target Chain Sequence 16 PDB ID(s) of Target Chain 16 UniProt (SwissProt) Recommended Name of Target Chain 16 UniProt (SwissProt) Entry Name of Target Chain 16 UniProt (SwissProt) Primary ID of Target Chain 16 UniProt (SwissProt) Secondary ID(s) of Target Chain 16 UniProt (SwissProt) Alternative ID(s) of Target Chain 16 UniProt (TrEMBL) Submitted Name of Target Chain 16 UniProt (TrEMBL) Entry Name of Target Chain 16 UniProt (TrEMBL) Primary ID of Target Chain 16 UniProt (TrEMBL) Secondary ID(s) of Target Chain 16 UniProt (TrEMBL) Alternative ID(s) of Target Chain 16 BindingDB Target Chain Sequence 17 PDB ID(s) of Target Chain 17 UniProt (SwissProt) Recommended Name of Target Chain 17 UniProt (SwissProt) Entry Name of Target Chain 17 UniProt (SwissProt) Primary ID of Target Chain 17 UniProt (SwissProt) Secondary ID(s) of Target Chain 17 UniProt (SwissProt) Alternative ID(s) of Target Chain 17 UniProt (TrEMBL) Submitted Name of Target Chain 17 UniProt (TrEMBL) Entry Name of Target Chain 17 UniProt (TrEMBL) Primary ID of Target Chain 17 UniProt (TrEMBL) Secondary ID(s) of Target Chain 17 UniProt (TrEMBL) Alternative ID(s) of Target Chain 17 BindingDB Target Chain Sequence 18 PDB ID(s) of Target Chain 18 UniProt (SwissProt) Recommended Name of Target Chain 18 UniProt (SwissProt) Entry Name of Target Chain 18 UniProt (SwissProt) Primary ID of Target Chain 18 UniProt (SwissProt) Secondary ID(s) of Target Chain 18 UniProt (SwissProt) Alternative ID(s) of Target Chain 18 UniProt (TrEMBL) Submitted Name of Target Chain 18 UniProt (TrEMBL) Entry Name of Target Chain 18 UniProt (TrEMBL) Primary ID of Target Chain 18 UniProt (TrEMBL) Secondary ID(s) of Target Chain 18 UniProt (TrEMBL) Alternative ID(s) of Target Chain 18 BindingDB Target Chain Sequence 19 PDB ID(s) of Target Chain 19 UniProt (SwissProt) Recommended Name of Target Chain 19 UniProt (SwissProt) Entry Name of Target Chain 19 UniProt (SwissProt) Primary ID of Target Chain 19 UniProt (SwissProt) Secondary ID(s) of Target Chain 19 UniProt (SwissProt) Alternative ID(s) of Target Chain 19 UniProt (TrEMBL) Submitted Name of Target Chain 19 UniProt (TrEMBL) Entry Name of Target Chain 19 UniProt (TrEMBL) Primary ID of Target Chain 19 UniProt (TrEMBL) Secondary ID(s) of Target Chain 19 UniProt (TrEMBL) Alternative ID(s) of Target Chain 19 BindingDB Target Chain Sequence 20 PDB ID(s) of Target Chain 20 UniProt (SwissProt) Recommended Name of Target Chain 20 UniProt (SwissProt) Entry Name of Target Chain 20 UniProt (SwissProt) Primary ID of Target Chain 20 UniProt (SwissProt) Secondary ID(s) of Target Chain 20 UniProt (SwissProt) Alternative ID(s) of Target Chain 20 UniProt (TrEMBL) Submitted Name of Target Chain 20 UniProt (TrEMBL) Entry Name of Target Chain 20 UniProt (TrEMBL) Primary ID of Target Chain 20 UniProt (TrEMBL) Secondary ID(s) of Target Chain 20 UniProt (TrEMBL) Alternative ID(s) of Target Chain 20 BindingDB Target Chain Sequence 21 PDB ID(s) of Target Chain 21 UniProt (SwissProt) Recommended Name of Target Chain 21 UniProt (SwissProt) Entry Name of Target Chain 21 UniProt (SwissProt) Primary ID of Target Chain 21 UniProt (SwissProt) Secondary ID(s) of Target Chain 21 UniProt (SwissProt) Alternative ID(s) of Target Chain 21 UniProt (TrEMBL) Submitted Name of Target Chain 21 UniProt (TrEMBL) Entry Name of Target Chain 21 UniProt (TrEMBL) Primary ID of Target Chain 21 UniProt (TrEMBL) Secondary ID(s) of Target Chain 21 UniProt (TrEMBL) Alternative ID(s) of Target Chain 21 BindingDB Target Chain Sequence 22 PDB ID(s) of Target Chain 22 UniProt (SwissProt) Recommended Name of Target Chain 22 UniProt (SwissProt) Entry Name of Target Chain 22 UniProt (SwissProt) Primary ID of Target Chain 22 UniProt (SwissProt) Secondary ID(s) of Target Chain 22 UniProt (SwissProt) Alternative ID(s) of Target Chain 22 UniProt (TrEMBL) Submitted Name of Target Chain 22 UniProt (TrEMBL) Entry Name of Target Chain 22 UniProt (TrEMBL) Primary ID of Target Chain 22 UniProt (TrEMBL) Secondary ID(s) of Target Chain 22 UniProt (TrEMBL) Alternative ID(s) of Target Chain 22 BindingDB Target Chain Sequence 23 PDB ID(s) of Target Chain 23 UniProt (SwissProt) Recommended Name of Target Chain 23 UniProt (SwissProt) Entry Name of Target Chain 23 UniProt (SwissProt) Primary ID of Target Chain 23 UniProt (SwissProt) Secondary ID(s) of Target Chain 23 UniProt (SwissProt) Alternative ID(s) of Target Chain 23 UniProt (TrEMBL) Submitted Name of Target Chain 23 UniProt (TrEMBL) Entry Name of Target Chain 23 UniProt (TrEMBL) Primary ID of Target Chain 23 UniProt (TrEMBL) Secondary ID(s) of Target Chain 23 UniProt (TrEMBL) Alternative ID(s) of Target Chain 23 BindingDB Target Chain Sequence 24 PDB ID(s) of Target Chain 24 UniProt (SwissProt) Recommended Name of Target Chain 24 UniProt (SwissProt) Entry Name of Target Chain 24 UniProt (SwissProt) Primary ID of Target Chain 24 UniProt (SwissProt) Secondary ID(s) of Target Chain 24 UniProt (SwissProt) Alternative ID(s) of Target Chain 24 UniProt (TrEMBL) Submitted Name of Target Chain 24 UniProt (TrEMBL) Entry Name of Target Chain 24 UniProt (TrEMBL) Primary ID of Target Chain 24 UniProt (TrEMBL) Secondary ID(s) of Target Chain 24 UniProt (TrEMBL) Alternative ID(s) of Target Chain 24 BindingDB Target Chain Sequence 25 PDB ID(s) of Target Chain 25 UniProt (SwissProt) Recommended Name of Target Chain 25 UniProt (SwissProt) Entry Name of Target Chain 25 UniProt (SwissProt) Primary ID of Target Chain 25 UniProt (SwissProt) Secondary ID(s) of Target Chain 25 UniProt (SwissProt) Alternative ID(s) of Target Chain 25 UniProt (TrEMBL) Submitted Name of Target Chain 25 UniProt (TrEMBL) Entry Name of Target Chain 25 UniProt (TrEMBL) Primary ID of Target Chain 25 UniProt (TrEMBL) Secondary ID(s) of Target Chain 25 UniProt (TrEMBL) Alternative ID(s) of Target Chain 25 BindingDB Target Chain Sequence 26 PDB ID(s) of Target Chain 26 UniProt (SwissProt) Recommended Name of Target Chain 26 UniProt (SwissProt) Entry Name of Target Chain 26 UniProt (SwissProt) Primary ID of Target Chain 26 UniProt (SwissProt) Secondary ID(s) of Target Chain 26 UniProt (SwissProt) Alternative ID(s) of Target Chain 26 UniProt (TrEMBL) Submitted Name of Target Chain 26 UniProt (TrEMBL) Entry Name of Target Chain 26 UniProt (TrEMBL) Primary ID of Target Chain 26 UniProt (TrEMBL) Secondary ID(s) of Target Chain 26 UniProt (TrEMBL) Alternative ID(s) of Target Chain 26 BindingDB Target Chain Sequence 27 PDB ID(s) of Target Chain 27 UniProt (SwissProt) Recommended Name of Target Chain 27 UniProt (SwissProt) Entry Name of Target Chain 27 UniProt (SwissProt) Primary ID of Target Chain 27 UniProt (SwissProt) Secondary ID(s) of Target Chain 27 UniProt (SwissProt) Alternative ID(s) of Target Chain 27 UniProt (TrEMBL) Submitted Name of Target Chain 27 UniProt (TrEMBL) Entry Name of Target Chain 27 UniProt (TrEMBL) Primary ID of Target Chain 27 UniProt (TrEMBL) Secondary ID(s) of Target Chain 27 UniProt (TrEMBL) Alternative ID(s) of Target Chain 27 BindingDB Target Chain Sequence 28 PDB ID(s) of Target Chain 28 UniProt (SwissProt) Recommended Name of Target Chain 28 UniProt (SwissProt) Entry Name of Target Chain 28 UniProt (SwissProt) Primary ID of Target Chain 28 UniProt (SwissProt) Secondary ID(s) of Target Chain 28 UniProt (SwissProt) Alternative ID(s) of Target Chain 28 UniProt (TrEMBL) Submitted Name of Target Chain 28 UniProt (TrEMBL) Entry Name of Target Chain 28 UniProt (TrEMBL) Primary ID of Target Chain 28 UniProt (TrEMBL) Secondary ID(s) of Target Chain 28 UniProt (TrEMBL) Alternative ID(s) of Target Chain 28 BindingDB Target Chain Sequence 29 PDB ID(s) of Target Chain 29 UniProt (SwissProt) Recommended Name of Target Chain 29 UniProt (SwissProt) Entry Name of Target Chain 29 UniProt (SwissProt) Primary ID of Target Chain 29 UniProt (SwissProt) Secondary ID(s) of Target Chain 29 UniProt (SwissProt) Alternative ID(s) of Target Chain 29 UniProt (TrEMBL) Submitted Name of Target Chain 29 UniProt (TrEMBL) Entry Name of Target Chain 29 UniProt (TrEMBL) Primary ID of Target Chain 29 UniProt (TrEMBL) Secondary ID(s) of Target Chain 29 UniProt (TrEMBL) Alternative ID(s) of Target Chain 29 BindingDB Target Chain Sequence 30 PDB ID(s) of Target Chain 30 UniProt (SwissProt) Recommended Name of Target Chain 30 UniProt (SwissProt) Entry Name of Target Chain 30 UniProt (SwissProt) Primary ID of Target Chain 30 UniProt (SwissProt) Secondary ID(s) of Target Chain 30 UniProt (SwissProt) Alternative ID(s) of Target Chain 30 UniProt (TrEMBL) Submitted Name of Target Chain 30 UniProt (TrEMBL) Entry Name of Target Chain 30 UniProt (TrEMBL) Primary ID of Target Chain 30 UniProt (TrEMBL) Secondary ID(s) of Target Chain 30 UniProt (TrEMBL) Alternative ID(s) of Target Chain 30 BindingDB Target Chain Sequence 31 PDB ID(s) of Target Chain 31 UniProt (SwissProt) Recommended Name of Target Chain 31 UniProt (SwissProt) Entry Name of Target Chain 31 UniProt (SwissProt) Primary ID of Target Chain 31 UniProt (SwissProt) Secondary ID(s) of Target Chain 31 UniProt (SwissProt) Alternative ID(s) of Target Chain 31 UniProt (TrEMBL) Submitted Name of Target Chain 31 UniProt (TrEMBL) Entry Name of Target Chain 31 UniProt (TrEMBL) Primary ID of Target Chain 31 UniProt (TrEMBL) Secondary ID(s) of Target Chain 31 UniProt (TrEMBL) Alternative ID(s) of Target Chain 31 BindingDB Target Chain Sequence 32 PDB ID(s) of Target Chain 32 UniProt (SwissProt) Recommended Name of Target Chain 32 UniProt (SwissProt) Entry Name of Target Chain 32 UniProt (SwissProt) Primary ID of Target Chain 32 UniProt (SwissProt) Secondary ID(s) of Target Chain 32 UniProt (SwissProt) Alternative ID(s) of Target Chain 32 UniProt (TrEMBL) Submitted Name of Target Chain 32 UniProt (TrEMBL) Entry Name of Target Chain 32 UniProt (TrEMBL) Primary ID of Target Chain 32 UniProt (TrEMBL) Secondary ID(s) of Target Chain 32 UniProt (TrEMBL) Alternative ID(s) of Target Chain 32 BindingDB Target Chain Sequence 33 PDB ID(s) of Target Chain 33 UniProt (SwissProt) Recommended Name of Target Chain 33 UniProt (SwissProt) Entry Name of Target Chain 33 UniProt (SwissProt) Primary ID of Target Chain 33 UniProt (SwissProt) Secondary ID(s) of Target Chain 33 UniProt (SwissProt) Alternative ID(s) of Target Chain 33 UniProt (TrEMBL) Submitted Name of Target Chain 33 UniProt (TrEMBL) Entry Name of Target Chain 33 UniProt (TrEMBL) Primary ID of Target Chain 33 UniProt (TrEMBL) Secondary ID(s) of Target Chain 33 UniProt (TrEMBL) Alternative ID(s) of Target Chain 33 BindingDB Target Chain Sequence 34 PDB ID(s) of Target Chain 34 UniProt (SwissProt) Recommended Name of Target Chain 34 UniProt (SwissProt) Entry Name of Target Chain 34 UniProt (SwissProt) Primary ID of Target Chain 34 UniProt (SwissProt) Secondary ID(s) of Target Chain 34 UniProt (SwissProt) Alternative ID(s) of Target Chain 34 UniProt (TrEMBL) Submitted Name of Target Chain 34 UniProt (TrEMBL) Entry Name of Target Chain 34 UniProt (TrEMBL) Primary ID of Target Chain 34 UniProt (TrEMBL) Secondary ID(s) of Target Chain 34 UniProt (TrEMBL) Alternative ID(s) of Target Chain 34 BindingDB Target Chain Sequence 35 PDB ID(s) of Target Chain 35 UniProt (SwissProt) Recommended Name of Target Chain 35 UniProt (SwissProt) Entry Name of Target Chain 35 UniProt (SwissProt) Primary ID of Target Chain 35 UniProt (SwissProt) Secondary ID(s) of Target Chain 35 UniProt (SwissProt) Alternative ID(s) of Target Chain 35 UniProt (TrEMBL) Submitted Name of Target Chain 35 UniProt (TrEMBL) Entry Name of Target Chain 35 UniProt (TrEMBL) Primary ID of Target Chain 35 UniProt (TrEMBL) Secondary ID(s) of Target Chain 35 UniProt (TrEMBL) Alternative ID(s) of Target Chain 35 BindingDB Target Chain Sequence 36 PDB ID(s) of Target Chain 36 UniProt (SwissProt) Recommended Name of Target Chain 36 UniProt (SwissProt) Entry Name of Target Chain 36 UniProt (SwissProt) Primary ID of Target Chain 36 UniProt (SwissProt) Secondary ID(s) of Target Chain 36 UniProt (SwissProt) Alternative ID(s) of Target Chain 36 UniProt (TrEMBL) Submitted Name of Target Chain 36 UniProt (TrEMBL) Entry Name of Target Chain 36 UniProt (TrEMBL) Primary ID of Target Chain 36 UniProt (TrEMBL) Secondary ID(s) of Target Chain 36 UniProt (TrEMBL) Alternative ID(s) of Target Chain 36 BindingDB Target Chain Sequence 37 PDB ID(s) of Target Chain 37 UniProt (SwissProt) Recommended Name of Target Chain 37 UniProt (SwissProt) Entry Name of Target Chain 37 UniProt (SwissProt) Primary ID of Target Chain 37 UniProt (SwissProt) Secondary ID(s) of Target Chain 37 UniProt (SwissProt) Alternative ID(s) of Target Chain 37 UniProt (TrEMBL) Submitted Name of Target Chain 37 UniProt (TrEMBL) Entry Name of Target Chain 37 UniProt (TrEMBL) Primary ID of Target Chain 37 UniProt (TrEMBL) Secondary ID(s) of Target Chain 37 UniProt (TrEMBL) Alternative ID(s) of Target Chain 37 BindingDB Target Chain Sequence 38 PDB ID(s) of Target Chain 38 UniProt (SwissProt) Recommended Name of Target Chain 38 UniProt (SwissProt) Entry Name of Target Chain 38 UniProt (SwissProt) Primary ID of Target Chain 38 UniProt (SwissProt) Secondary ID(s) of Target Chain 38 UniProt (SwissProt) Alternative ID(s) of Target Chain 38 UniProt (TrEMBL) Submitted Name of Target Chain 38 UniProt (TrEMBL) Entry Name of Target Chain 38 UniProt (TrEMBL) Primary ID of Target Chain 38 UniProt (TrEMBL) Secondary ID(s) of Target Chain 38 UniProt (TrEMBL) Alternative ID(s) of Target Chain 38 BindingDB Target Chain Sequence 39 PDB ID(s) of Target Chain 39 UniProt (SwissProt) Recommended Name of Target Chain 39 UniProt (SwissProt) Entry Name of Target Chain 39 UniProt (SwissProt) Primary ID of Target Chain 39 UniProt (SwissProt) Secondary ID(s) of Target Chain 39 UniProt (SwissProt) Alternative ID(s) of Target Chain 39 UniProt (TrEMBL) Submitted Name of Target Chain 39 UniProt (TrEMBL) Entry Name of Target Chain 39 UniProt (TrEMBL) Primary ID of Target Chain 39 UniProt (TrEMBL) Secondary ID(s) of Target Chain 39 UniProt (TrEMBL) Alternative ID(s) of Target Chain 39 BindingDB Target Chain Sequence 40 PDB ID(s) of Target Chain 40 UniProt (SwissProt) Recommended Name of Target Chain 40 UniProt (SwissProt) Entry Name of Target Chain 40 UniProt (SwissProt) Primary ID of Target Chain 40 UniProt (SwissProt) Secondary ID(s) of Target Chain 40 UniProt (SwissProt) Alternative ID(s) of Target Chain 40 UniProt (TrEMBL) Submitted Name of Target Chain 40 UniProt (TrEMBL) Entry Name of Target Chain 40 UniProt (TrEMBL) Primary ID of Target Chain 40 UniProt (TrEMBL) Secondary ID(s) of Target Chain 40 UniProt (TrEMBL) Alternative ID(s) of Target Chain 40 BindingDB Target Chain Sequence 41 PDB ID(s) of Target Chain 41 UniProt (SwissProt) Recommended Name of Target Chain 41 UniProt (SwissProt) Entry Name of Target Chain 41 UniProt (SwissProt) Primary ID of Target Chain 41 UniProt (SwissProt) Secondary ID(s) of Target Chain 41 UniProt (SwissProt) Alternative ID(s) of Target Chain 41 UniProt (TrEMBL) Submitted Name of Target Chain 41 UniProt (TrEMBL) Entry Name of Target Chain 41 UniProt (TrEMBL) Primary ID of Target Chain 41 UniProt (TrEMBL) Secondary ID(s) of Target Chain 41 UniProt (TrEMBL) Alternative ID(s) of Target Chain 41 BindingDB Target Chain Sequence 42 PDB ID(s) of Target Chain 42 UniProt (SwissProt) Recommended Name of Target Chain 42 UniProt (SwissProt) Entry Name of Target Chain 42 UniProt (SwissProt) Primary ID of Target Chain 42 UniProt (SwissProt) Secondary ID(s) of Target Chain 42 UniProt (SwissProt) Alternative ID(s) of Target Chain 42 UniProt (TrEMBL) Submitted Name of Target Chain 42 UniProt (TrEMBL) Entry Name of Target Chain 42 UniProt (TrEMBL) Primary ID of Target Chain 42 UniProt (TrEMBL) Secondary ID(s) of Target Chain 42 UniProt (TrEMBL) Alternative ID(s) of Target Chain 42 BindingDB Target Chain Sequence 43 PDB ID(s) of Target Chain 43 UniProt (SwissProt) Recommended Name of Target Chain 43 UniProt (SwissProt) Entry Name of Target Chain 43 UniProt (SwissProt) Primary ID of Target Chain 43 UniProt (SwissProt) Secondary ID(s) of Target Chain 43 UniProt (SwissProt) Alternative ID(s) of Target Chain 43 UniProt (TrEMBL) Submitted Name of Target Chain 43 UniProt (TrEMBL) Entry Name of Target Chain 43 UniProt (TrEMBL) Primary ID of Target Chain 43 UniProt (TrEMBL) Secondary ID(s) of Target Chain 43 UniProt (TrEMBL) Alternative ID(s) of Target Chain 43 BindingDB Target Chain Sequence 44 PDB ID(s) of Target Chain 44 UniProt (SwissProt) Recommended Name of Target Chain 44 UniProt (SwissProt) Entry Name of Target Chain 44 UniProt (SwissProt) Primary ID of Target Chain 44 UniProt (SwissProt) Secondary ID(s) of Target Chain 44 UniProt (SwissProt) Alternative ID(s) of Target Chain 44 UniProt (TrEMBL) Submitted Name of Target Chain 44 UniProt (TrEMBL) Entry Name of Target Chain 44 UniProt (TrEMBL) Primary ID of Target Chain 44 UniProt (TrEMBL) Secondary ID(s) of Target Chain 44 UniProt (TrEMBL) Alternative ID(s) of Target Chain 44 BindingDB Target Chain Sequence 45 PDB ID(s) of Target Chain 45 UniProt (SwissProt) Recommended Name of Target Chain 45 UniProt (SwissProt) Entry Name of Target Chain 45 UniProt (SwissProt) Primary ID of Target Chain 45 UniProt (SwissProt) Secondary ID(s) of Target Chain 45 UniProt (SwissProt) Alternative ID(s) of Target Chain 45 UniProt (TrEMBL) Submitted Name of Target Chain 45 UniProt (TrEMBL) Entry Name of Target Chain 45 UniProt (TrEMBL) Primary ID of Target Chain 45 UniProt (TrEMBL) Secondary ID(s) of Target Chain 45 UniProt (TrEMBL) Alternative ID(s) of Target Chain 45 BindingDB Target Chain Sequence 46 PDB ID(s) of Target Chain 46 UniProt (SwissProt) Recommended Name of Target Chain 46 UniProt (SwissProt) Entry Name of Target Chain 46 UniProt (SwissProt) Primary ID of Target Chain 46 UniProt (SwissProt) Secondary ID(s) of Target Chain 46 UniProt (SwissProt) Alternative ID(s) of Target Chain 46 UniProt (TrEMBL) Submitted Name of Target Chain 46 UniProt (TrEMBL) Entry Name of Target Chain 46 UniProt (TrEMBL) Primary ID of Target Chain 46 UniProt (TrEMBL) Secondary ID(s) of Target Chain 46 UniProt (TrEMBL) Alternative ID(s) of Target Chain 46 BindingDB Target Chain Sequence 47 PDB ID(s) of Target Chain 47 UniProt (SwissProt) Recommended Name of Target Chain 47 UniProt (SwissProt) Entry Name of Target Chain 47 UniProt (SwissProt) Primary ID of Target Chain 47 UniProt (SwissProt) Secondary ID(s) of Target Chain 47 UniProt (SwissProt) Alternative ID(s) of Target Chain 47 UniProt (TrEMBL) Submitted Name of Target Chain 47 UniProt (TrEMBL) Entry Name of Target Chain 47 UniProt (TrEMBL) Primary ID of Target Chain 47 UniProt (TrEMBL) Secondary ID(s) of Target Chain 47 UniProt (TrEMBL) Alternative ID(s) of Target Chain 47 BindingDB Target Chain Sequence 48 PDB ID(s) of Target Chain 48 UniProt (SwissProt) Recommended Name of Target Chain 48 UniProt (SwissProt) Entry Name of Target Chain 48 UniProt (SwissProt) Primary ID of Target Chain 48 UniProt (SwissProt) Secondary ID(s) of Target Chain 48 UniProt (SwissProt) Alternative ID(s) of Target Chain 48 UniProt (TrEMBL) Submitted Name of Target Chain 48 UniProt (TrEMBL) Entry Name of Target Chain 48 UniProt (TrEMBL) Primary ID of Target Chain 48 UniProt (TrEMBL) Secondary ID(s) of Target Chain 48 UniProt (TrEMBL) Alternative ID(s) of Target Chain 48 BindingDB Target Chain Sequence 49 PDB ID(s) of Target Chain 49 UniProt (SwissProt) Recommended Name of Target Chain 49 UniProt (SwissProt) Entry Name of Target Chain 49 UniProt (SwissProt) Primary ID of Target Chain 49 UniProt (SwissProt) Secondary ID(s) of Target Chain 49 UniProt (SwissProt) Alternative ID(s) of Target Chain 49 UniProt (TrEMBL) Submitted Name of Target Chain 49 UniProt (TrEMBL) Entry Name of Target Chain 49 UniProt (TrEMBL) Primary ID of Target Chain 49 UniProt (TrEMBL) Secondary ID(s) of Target Chain 49 UniProt (TrEMBL) Alternative ID(s) of Target Chain 49 BindingDB Target Chain Sequence 50 PDB ID(s) of Target Chain 50 UniProt (SwissProt) Recommended Name of Target Chain 50 UniProt (SwissProt) Entry Name of Target Chain 50 UniProt (SwissProt) Primary ID of Target Chain 50 UniProt (SwissProt) Secondary ID(s) of Target Chain 50 UniProt (SwissProt) Alternative ID(s) of Target Chain 50 UniProt (TrEMBL) Submitted Name of Target Chain 50 UniProt (TrEMBL) Entry Name of Target Chain 50 UniProt (TrEMBL) Primary ID of Target Chain 50 UniProt (TrEMBL) Secondary ID(s) of Target Chain 50 UniProt (TrEMBL) Alternative ID(s) of Target Chain 50 50059730 CCCCCNC(=O)Nc1cccc(OCCCn2cnc(c2C)-c2ccccc2)c1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-23-15-11-16-24(26(23)31(3)4)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) LRVUGZAEMOZNTD-UHFFFAOYSA-N 50047514 1-{2-Dimethylamino-3-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL297206 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 5800 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047514 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047514&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10050060 103978107 CHEMBL297206 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059731 CCCCCNC(=O)Nc1c(OCCCNCCc2ccccc2)cccc1N(C)C InChI=1S/C25H38N4O2/c1-4-5-9-18-27-25(30)28-24-22(29(2)3)14-10-15-23(24)31-20-11-17-26-19-16-21-12-7-6-8-13-21/h6-8,10,12-15,26H,4-5,9,11,16-20H2,1-3H3,(H2,27,28,30) OCJBFQGTZBBHON-UHFFFAOYSA-N 50047524 1-[2-Dimethylamino-6-(3-phenethylamino-propoxy)-phenyl]-3-pentyl-urea::CHEMBL288771 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 960 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047524 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047524&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10477575 103978117 CHEMBL288771 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059732 CCCCCNC(=O)Nc1c(OCCCn2nnc(n2)-c2ccccc2)cccc1N(C)C InChI=1S/C24H33N7O2/c1-4-5-9-16-25-24(32)26-22-20(30(2)3)14-10-15-21(22)33-18-11-17-31-28-23(27-29-31)19-12-7-6-8-13-19/h6-8,10,12-15H,4-5,9,11,16-18H2,1-3H3,(H2,25,26,32) KURZETMTYGSFCT-UHFFFAOYSA-N 50047509 1-{2-Dimethylamino-6-[3-(5-phenyl-tetrazol-2-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL47071 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 230 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047509 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047509&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10095350 103978102 CHEMBL47071 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059733 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C26H35N5O2/c1-4-5-9-16-27-26(32)29-25-23(30(2)3)14-10-15-24(25)33-18-11-17-31-19-22(28-20-31)21-12-7-6-8-13-21/h6-8,10,12-15,19-20H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,32) CZOTZWJSMLDBSH-UHFFFAOYSA-N 50047495 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL440475 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 31 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047495 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047495&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 9824974 103978088 CHEMBL440475 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059736 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)ncnc1N(C)C InChI=1S/C25H35N7O2/c1-5-6-10-14-26-25(33)30-22-23(31(3)4)27-17-28-24(22)34-16-11-15-32-18-29-21(19(32)2)20-12-8-7-9-13-20/h7-9,12-13,17-18H,5-6,10-11,14-16H2,1-4H3,(H2,26,30,33) GJZBXZYBMAYHRE-UHFFFAOYSA-N 50047522 1-{4-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-pyrimidin-5-yl}-3-pentyl-urea::CHEMBL42111 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 5500 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047522 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047522&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10389772 103978115 CHEMBL42111 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059739 CCCCCNC(=O)Nc1c(OCCCNCCc2ccccc2)cccc1N(C)C InChI=1S/C25H38N4O2/c1-4-5-9-18-27-25(30)28-24-22(29(2)3)14-10-15-23(24)31-20-11-17-26-19-16-21-12-7-6-8-13-21/h6-8,10,12-15,26H,4-5,9,11,16-20H2,1-3H3,(H2,27,28,30) OCJBFQGTZBBHON-UHFFFAOYSA-N 50047524 1-[2-Dimethylamino-6-(3-phenethylamino-propoxy)-phenyl]-3-pentyl-urea::CHEMBL288771 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 3440 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047524 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047524&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10477575 103978117 CHEMBL288771 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059742 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(OC)cc2)c(Br)cc(Br)c1N(C)C InChI=1S/C27H35Br2N5O3/c1-5-6-7-13-30-27(35)32-24-25(33(2)3)21(28)16-22(29)26(24)37-15-8-14-34-17-23(31-18-34)19-9-11-20(36-4)12-10-19/h9-12,16-18H,5-8,13-15H2,1-4H3,(H2,30,32,35) NDHLGVPBOLIMQN-UHFFFAOYSA-N 50047519 1-(3,5-Dibromo-2-dimethylamino-6-{3-[4-(4-methoxy-phenyl)-imidazol-1-yl]-propoxy}-phenyl)-3-pentyl-urea::CHEMBL295979 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 2400 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047519 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047519&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10394335 103978112 CHEMBL295979 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059745 CN(C)c1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NC1CCCCC1 InChI=1S/C27H35N5O2/c1-31(2)24-15-9-16-25(26(24)30-27(33)29-22-13-7-4-8-14-22)34-18-10-17-32-19-23(28-20-32)21-11-5-3-6-12-21/h3,5-6,9,11-12,15-16,19-20,22H,4,7-8,10,13-14,17-18H2,1-2H3,(H2,29,30,33) QOWNCIVDLGZPNQ-UHFFFAOYSA-N 50047520 1-Cyclohexyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL290627 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 73 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047520 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047520&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10027328 103978113 CHEMBL290627 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059755 CCCCCC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C26H34N4O2/c1-4-5-7-16-25(31)28-26-23(29(2)3)14-10-15-24(26)32-18-11-17-30-19-22(27-20-30)21-12-8-6-9-13-21/h6,8-10,12-15,19-20H,4-5,7,11,16-18H2,1-3H3,(H,28,31) JJZDMZHYPPAQNX-UHFFFAOYSA-N 50047515 Hexanoic acid {2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-amide::CHEMBL46738 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 200 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047515 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047515&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 11743656 103978108 CHEMBL46738 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059758 CN(C)c1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NC(C)(C)C InChI=1S/C25H33N5O2/c1-25(2,3)28-24(31)27-23-21(29(4)5)13-9-14-22(23)32-16-10-15-30-17-20(26-18-30)19-11-7-6-8-12-19/h6-9,11-14,17-18H,10,15-16H2,1-5H3,(H2,27,28,31) PIZKWMLQOPEHGM-UHFFFAOYSA-N 50047500 1-tert-Butyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL298486 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 130 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047500 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047500&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10003115 103978093 CHEMBL298486 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059760 CCCCCNC(=O)Nc1c(NCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C27H38N6O/c1-5-6-10-17-29-27(34)31-26-23(15-11-16-24(26)32(3)4)28-18-12-19-33-20-30-25(21(33)2)22-13-8-7-9-14-22/h7-9,11,13-16,20,28H,5-6,10,12,17-19H2,1-4H3,(H2,29,31,34) NMLREFBZXBPANR-UHFFFAOYSA-N 50047518 1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propylamino]-phenyl}-3-pentyl-urea::CHEMBL41127 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 470 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047518 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047518&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10367104 103978111 CHEMBL41127 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059761 CCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C24H31N5O2/c1-4-14-25-24(30)27-23-21(28(2)3)12-8-13-22(23)31-16-9-15-29-17-20(26-18-29)19-10-6-5-7-11-19/h5-8,10-13,17-18H,4,9,14-16H2,1-3H3,(H2,25,27,30) VYWKZXUTPFZFLB-UHFFFAOYSA-N 50047507 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-propyl-urea::CHEMBL41960 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 660 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047507 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047507&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10025201 103978100 CHEMBL41960 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059762 CCCCCNC(=O)Nc1c(OCCCn2nc3ccccc3n2)cccc1N(C)C InChI=1S/C23H32N6O2/c1-4-5-8-15-24-23(30)25-22-20(28(2)3)13-9-14-21(22)31-17-10-16-29-26-18-11-6-7-12-19(18)27-29/h6-7,9,11-14H,4-5,8,10,15-17H2,1-3H3,(H2,24,25,30) VLKPZPIMEYVDQR-UHFFFAOYSA-N 50047513 1-[2-(3-Benzotriazol-2-yl-propoxy)-6-dimethylamino-phenyl]-3-pentyl-urea::CHEMBL44471 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 290 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047513 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047513&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10093846 103978106 CHEMBL44471 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059763 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2cccc3ccccc23)cccc1N(C)C InChI=1S/C30H37N5O2/c1-4-5-8-18-31-30(36)33-29-27(34(2)3)16-10-17-28(29)37-20-11-19-35-21-26(32-22-35)25-15-9-13-23-12-6-7-14-24(23)25/h6-7,9-10,12-17,21-22H,4-5,8,11,18-20H2,1-3H3,(H2,31,33,36) KCNZHXUNAXRGCI-UHFFFAOYSA-N 50047502 1-{2-Dimethylamino-6-[3-(4-naphthalen-1-yl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42082 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 1550 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047502 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047502&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 44288850 103978095 CHEMBL42082 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059764 CCCCCNC(=O)Nc1c(OCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C25H33N5O2/c1-4-5-9-15-26-25(31)28-24-22(29(2)3)13-10-14-23(24)32-17-16-30-18-21(27-19-30)20-11-7-6-8-12-20/h6-8,10-14,18-19H,4-5,9,15-17H2,1-3H3,(H2,26,28,31) WEPJCYOFKWLPHG-UHFFFAOYSA-N 50047510 1-{2-Dimethylamino-6-[2-(4-phenyl-imidazol-1-yl)-ethoxy]-phenyl}-3-pentyl-urea::CHEMBL42813 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 1400 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047510 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047510&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 9980424 103978103 CHEMBL42813 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059765 CCCCCNC(=O)Nc1c(OCCCn2ncc(n2)-c2ccccc2)cccc1N(C)C InChI=1S/C25H34N6O2/c1-4-5-9-16-26-25(32)28-24-22(30(2)3)14-10-15-23(24)33-18-11-17-31-27-19-21(29-31)20-12-7-6-8-13-20/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,26,28,32) IJCSMICAOAEMOB-UHFFFAOYSA-N 50047511 1-{2-Dimethylamino-6-[3-(4-phenyl-[1,2,3]triazol-2-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL44071 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 180 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047511 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047511&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10253246 103978104 CHEMBL44071 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059766 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(OC)cc2)cccc1N(C)C InChI=1S/C27H37N5O3/c1-5-6-7-16-28-27(33)30-26-24(31(2)3)10-8-11-25(26)35-18-9-17-32-19-23(29-20-32)21-12-14-22(34-4)15-13-21/h8,10-15,19-20H,5-7,9,16-18H2,1-4H3,(H2,28,30,33) FETJCLFYGUTKOI-UHFFFAOYSA-N 50047526 1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-imidazol-1-yl]-propoxy}-phenyl)-3-pentyl-urea::CHEMBL42942 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 1330 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047526 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047526&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10412851 103978119 CHEMBL42942 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059767 CCCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-4-5-6-10-17-28-27(33)30-26-24(31(2)3)15-11-16-25(26)34-19-12-18-32-20-23(29-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,33) CSTKENWENAOKCJ-UHFFFAOYSA-N 50047493 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-hexyl-urea::CHEMBL42765 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 50 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047493 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047493&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10389684 103978086 CHEMBL42765 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059768 CCCCCNC(=O)Nc1cc(OCCCn2cnc(c2C)-c2ccccc2)ccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-16-28-27(33)30-24-19-23(14-15-25(24)31(3)4)34-18-11-17-32-20-29-26(21(32)2)22-12-8-7-9-13-22/h7-9,12-15,19-20H,5-6,10-11,16-18H2,1-4H3,(H2,28,30,33) CXZWCIQHJJIWSH-UHFFFAOYSA-N 50047498 1-{2-Dimethylamino-5-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL41992 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 410 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047498&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10367148 103978091 CHEMBL41992 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059771 CN(C)c1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NC1CCCC1 InChI=1S/C26H33N5O2/c1-30(2)23-14-8-15-24(25(23)29-26(32)28-21-12-6-7-13-21)33-17-9-16-31-18-22(27-19-31)20-10-4-3-5-11-20/h3-5,8,10-11,14-15,18-19,21H,6-7,9,12-13,16-17H2,1-2H3,(H2,28,29,32) MSLBOGVJFFFZOS-UHFFFAOYSA-N 50047506 1-Cyclopentyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL287842 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 3530 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047506 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047506&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10456284 103978099 CHEMBL287842 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059772 CCCCCNC(=O)Nc1c(SCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5OS/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) QNPISZGNCXWJBI-UHFFFAOYSA-N 50047529 1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propylsulfanyl]-phenyl}-3-pentyl-urea::CHEMBL42045 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 58 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047529 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047529&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10254549 103978122 CHEMBL42045 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059773 CCCCCCNc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C26H36N4O/c1-4-5-6-10-17-27-26-24(29(2)3)15-11-16-25(26)31-19-12-18-30-20-23(28-21-30)22-13-8-7-9-14-22/h7-9,11,13-16,20-21,27H,4-6,10,12,17-19H2,1-3H3 GWNGILGEXQCQQI-UHFFFAOYSA-N 50047496 N*2*-Hexyl-N*1*,N*1*-dimethyl-3-[3-(4-phenyl-imidazol-1-yl)-propoxy]-benzene-1,2-diamine::CHEMBL44495 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 3300 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047496 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047496&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10364847 103978089 CHEMBL44495 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059774 CCCCCCNc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C26H36N4O/c1-4-5-6-10-17-27-26-24(29(2)3)15-11-16-25(26)31-19-12-18-30-20-23(28-21-30)22-13-8-7-9-14-22/h7-9,11,13-16,20-21,27H,4-6,10,12,17-19H2,1-3H3 GWNGILGEXQCQQI-UHFFFAOYSA-N 50047496 N*2*-Hexyl-N*1*,N*1*-dimethyl-3-[3-(4-phenyl-imidazol-1-yl)-propoxy]-benzene-1,2-diamine::CHEMBL44495 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 11000 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047496 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047496&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10364847 103978089 CHEMBL44495 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059776 CCCCCNC(=O)N(C)c1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)31(4)26-24(30(2)3)15-11-16-25(26)34-19-12-18-32-20-23(29-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H,28,33) QGDAAIPGJQYTCF-UHFFFAOYSA-N 50047516 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-1-methyl-3-pentyl-urea::CHEMBL42395 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 930 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047516 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047516&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 11754155 103978109 CHEMBL42395 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059777 CCCCCNC(=O)Nc1c(OCCCN2CCN(CC2)c2ccccc2)cccc1N(C)C InChI=1S/C27H41N5O2/c1-4-5-9-16-28-27(33)29-26-24(30(2)3)14-10-15-25(26)34-22-11-17-31-18-20-32(21-19-31)23-12-7-6-8-13-23/h6-8,10,12-15H,4-5,9,11,16-22H2,1-3H3,(H2,28,29,33) WCEUIQJKUJZNNO-UHFFFAOYSA-N 50047525 1-{2-Dimethylamino-6-[3-(4-phenyl-piperazin-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42166 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 180 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047525 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047525&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 11754350 103978118 CHEMBL42166 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059778 CCCCCNC(=O)Nc1c(OCCCn2nnc(n2)-c2ccccc2)cccc1N(C)C InChI=1S/C24H33N7O2/c1-4-5-9-16-25-24(32)26-22-20(30(2)3)14-10-15-21(22)33-18-11-17-31-28-23(27-29-31)19-12-7-6-8-13-19/h6-8,10,12-15H,4-5,9,11,16-18H2,1-3H3,(H2,25,26,32) KURZETMTYGSFCT-UHFFFAOYSA-N 50047509 1-{2-Dimethylamino-6-[3-(5-phenyl-tetrazol-2-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL47071 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 23 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047509 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047509&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10095350 103978102 CHEMBL47071 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059780 CCCCCNC(=O)Nc1c(OCCCn2ncc(n2)-c2ccccc2)cccc1N(C)C InChI=1S/C25H34N6O2/c1-4-5-9-16-26-25(32)28-24-22(30(2)3)14-10-15-23(24)33-18-11-17-31-27-19-21(29-31)20-12-7-6-8-13-20/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,26,28,32) IJCSMICAOAEMOB-UHFFFAOYSA-N 50047511 1-{2-Dimethylamino-6-[3-(4-phenyl-[1,2,3]triazol-2-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL44071 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 32 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047511 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047511&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10253246 103978104 CHEMBL44071 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059781 CCCCCNC(=O)Nc1c(OCCCn2ccnc2-c2ccccc2)cccc1N(C)C InChI=1S/C26H35N5O2/c1-4-5-9-16-28-26(32)29-24-22(30(2)3)14-10-15-23(24)33-20-11-18-31-19-17-27-25(31)21-12-7-6-8-13-21/h6-8,10,12-15,17,19H,4-5,9,11,16,18,20H2,1-3H3,(H2,28,29,32) DMCPUDAATOTVFE-UHFFFAOYSA-N 50047512 1-{2-Dimethylamino-6-[3-(2-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL296421 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 480 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047512 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047512&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10095254 103978105 CHEMBL296421 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059782 CCCCCNC(=O)Nc1c(OCCCN2CCC(CC2)c2ccccc2)cccc1N(C)C InChI=1S/C28H42N4O2/c1-4-5-9-18-29-28(33)30-27-25(31(2)3)14-10-15-26(27)34-22-11-19-32-20-16-24(17-21-32)23-12-7-6-8-13-23/h6-8,10,12-15,24H,4-5,9,11,16-22H2,1-3H3,(H2,29,30,33) NDOWHJVXVUAWQD-UHFFFAOYSA-N 50047494 1-{2-Dimethylamino-6-[3-(4-phenyl-piperidin-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42668 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 470 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047494 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047494&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 9982006 103978087 CHEMBL42668 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059783 CCCCCN(C)C(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-31(4)27(33)29-26-24(30(2)3)15-11-16-25(26)34-19-12-18-32-20-23(28-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H,29,33) BQUFBLKXHOGXFE-UHFFFAOYSA-N 50047503 3-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-1-methyl-1-pentyl-urea::CHEMBL43036 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 280 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047503 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047503&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10095943 103978096 CHEMBL43036 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059784 CCCCCNC(=O)Nc1c(OCCCn2nc3ccccc3n2)cccc1N(C)C InChI=1S/C23H32N6O2/c1-4-5-8-15-24-23(30)25-22-20(28(2)3)13-9-14-21(22)31-17-10-16-29-26-18-11-6-7-12-19(18)27-29/h6-7,9,11-14H,4-5,8,10,15-17H2,1-3H3,(H2,24,25,30) VLKPZPIMEYVDQR-UHFFFAOYSA-N 50047513 1-[2-(3-Benzotriazol-2-yl-propoxy)-6-dimethylamino-phenyl]-3-pentyl-urea::CHEMBL44471 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 770 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047513 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047513&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10093846 103978106 CHEMBL44471 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059786 CCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C25H33N5O2/c1-4-5-15-26-25(31)28-24-22(29(2)3)13-9-14-23(24)32-17-10-16-30-18-21(27-19-30)20-11-7-6-8-12-20/h6-9,11-14,18-19H,4-5,10,15-17H2,1-3H3,(H2,26,28,31) PPXVURQJPIDTTG-UHFFFAOYSA-N 50047527 1-Butyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL43109 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 140 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047527 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047527&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10388270 103978120 CHEMBL43109 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059787 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(CCCC)cc2)cccc1N(C)C InChI=1S/C30H43N5O2/c1-5-7-9-19-31-30(36)33-29-27(34(3)4)13-10-14-28(29)37-21-11-20-35-22-26(32-23-35)25-17-15-24(16-18-25)12-8-6-2/h10,13-18,22-23H,5-9,11-12,19-21H2,1-4H3,(H2,31,33,36) KGLIRNVBEZUXJQ-UHFFFAOYSA-N 50047517 1-(2-{3-[4-(4-Butyl-phenyl)-imidazol-1-yl]-propoxy}-6-dimethylamino-phenyl)-3-pentyl-urea::CHEMBL43505 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 430 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047517 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047517&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10346068 103978110 CHEMBL43505 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059788 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(OC)cc2)c(Br)cc(Br)c1N(C)C InChI=1S/C27H35Br2N5O3/c1-5-6-7-13-30-27(35)32-24-25(33(2)3)21(28)16-22(29)26(24)37-15-8-14-34-17-23(31-18-34)19-9-11-20(36-4)12-10-19/h9-12,16-18H,5-8,13-15H2,1-4H3,(H2,30,32,35) NDHLGVPBOLIMQN-UHFFFAOYSA-N 50047519 1-(3,5-Dibromo-2-dimethylamino-6-{3-[4-(4-methoxy-phenyl)-imidazol-1-yl]-propoxy}-phenyl)-3-pentyl-urea::CHEMBL295979 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 1300 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047519 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047519&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10394335 103978112 CHEMBL295979 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059789 CCCCCNC(=O)Nc1c(SCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5OS/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) QNPISZGNCXWJBI-UHFFFAOYSA-N 50047529 1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propylsulfanyl]-phenyl}-3-pentyl-urea::CHEMBL42045 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 56 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047529 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047529&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10254549 103978122 CHEMBL42045 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059791 CCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C25H33N5O2/c1-4-5-15-26-25(31)28-24-22(29(2)3)13-9-14-23(24)32-17-10-16-30-18-21(27-19-30)20-11-7-6-8-12-20/h6-9,11-14,18-19H,4-5,10,15-17H2,1-3H3,(H2,26,28,31) PPXVURQJPIDTTG-UHFFFAOYSA-N 50047527 1-Butyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL43109 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 810 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047527 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047527&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10388270 103978120 CHEMBL43109 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059794 CCCCCNC(=O)Nc1c(OCCCn2cnc3ccccc23)cccc1N(C)C InChI=1S/C24H33N5O2/c1-4-5-8-15-25-24(30)27-23-21(28(2)3)13-9-14-22(23)31-17-10-16-29-18-26-19-11-6-7-12-20(19)29/h6-7,9,11-14,18H,4-5,8,10,15-17H2,1-3H3,(H2,25,27,30) AFXKWXLBLYFGRF-UHFFFAOYSA-N 50047528 1-[2-(3-Benzoimidazol-1-yl-propoxy)-6-dimethylamino-phenyl]-3-pentyl-urea::CHEMBL40516 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 620 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047528 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047528&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10251723 103978121 CHEMBL40516 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059795 CCCCCNC(=O)Nc1c(ccc(C)c1OCCCn1cnc(c1)-c1ccccc1)N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-16-28-27(33)30-25-24(31(3)4)15-14-21(2)26(25)34-18-11-17-32-19-23(29-20-32)22-12-8-7-9-13-22/h7-9,12-15,19-20H,5-6,10-11,16-18H2,1-4H3,(H2,28,30,33) FEPXBGTVAGOACR-UHFFFAOYSA-N 50047521 1-{6-Dimethylamino-3-methyl-2-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL291173 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 410 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047521 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047521&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10367147 103978114 CHEMBL291173 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059796 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)ncnc1N(C)C InChI=1S/C25H35N7O2/c1-5-6-10-14-26-25(33)30-22-23(31(3)4)27-17-28-24(22)34-16-11-15-32-18-29-21(19(32)2)20-12-8-7-9-13-20/h7-9,12-13,17-18H,5-6,10-11,14-16H2,1-4H3,(H2,26,30,33) GJZBXZYBMAYHRE-UHFFFAOYSA-N 50047522 1-{4-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-pyrimidin-5-yl}-3-pentyl-urea::CHEMBL42111 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 11000 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047522 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047522&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10389772 103978115 CHEMBL42111 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059797 CCCCCNC(=O)Nc1cccc(OCCCn2cnc(c2C)-c2ccccc2)c1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-23-15-11-16-24(26(23)31(3)4)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) LRVUGZAEMOZNTD-UHFFFAOYSA-N 50047514 1-{2-Dimethylamino-3-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL297206 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 3200 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047514 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047514&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10050060 103978107 CHEMBL297206 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059799 CCCCCNC(=O)Nc1c(OCCCn2cnc(C)c2-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-25-23(31(3)4)15-11-16-24(25)34-19-12-18-32-20-29-21(2)26(32)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) CVMNIXDUMPWJQL-UHFFFAOYSA-N 50047501 1-{2-Dimethylamino-6-[3-(4-methyl-5-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL43362 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 210 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047501 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047501&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10412078 103978094 CHEMBL43362 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059800 CCCCCN(C)C(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-31(4)27(33)29-26-24(30(2)3)15-11-16-25(26)34-19-12-18-32-20-23(28-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H,29,33) BQUFBLKXHOGXFE-UHFFFAOYSA-N 50047503 3-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-1-methyl-1-pentyl-urea::CHEMBL43036 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 550 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047503 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047503&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10095943 103978096 CHEMBL43036 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059801 CCCCCCCN(Cc1ccc(CC(C)(C)C)cc1)C(=O)Nc1ccc(F)cc1F InChI=1S/C26H36F2N2O/c1-5-6-7-8-9-16-30(25(31)29-24-15-14-22(27)17-23(24)28)19-21-12-10-20(11-13-21)18-26(2,3)4/h10-15,17H,5-9,16,18-19H2,1-4H3,(H,29,31) QKJLDOBXDUVGEE-UHFFFAOYSA-N 50022279 CL-277082::3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)-benzyl]-1-heptyl-urea::CHEMBL277986 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 180 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022279 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022279&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 125893 103932899 CHEMBL277986 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059802 CCCCCNC(=O)Nc1c(OCCCN2CCN(CC2)c2ccccc2)cccc1N(C)C InChI=1S/C27H41N5O2/c1-4-5-9-16-28-27(33)29-26-24(30(2)3)14-10-15-25(26)34-22-11-17-31-18-20-32(21-19-31)23-12-7-6-8-13-23/h6-8,10,12-15H,4-5,9,11,16-22H2,1-3H3,(H2,28,29,33) WCEUIQJKUJZNNO-UHFFFAOYSA-N 50047525 1-{2-Dimethylamino-6-[3-(4-phenyl-piperazin-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42166 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 17 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047525 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047525&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 11754350 103978118 CHEMBL42166 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059803 CCCCCNC(=O)Nc1c(OCCCN2CCC(CC2)c2ccccc2)cccc1N(C)C InChI=1S/C28H42N4O2/c1-4-5-9-18-29-28(33)30-27-25(31(2)3)14-10-15-26(27)34-22-11-19-32-20-16-24(17-21-32)23-12-7-6-8-13-23/h6-8,10,12-15,24H,4-5,9,11,16-22H2,1-3H3,(H2,29,30,33) NDOWHJVXVUAWQD-UHFFFAOYSA-N 50047494 1-{2-Dimethylamino-6-[3-(4-phenyl-piperidin-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42668 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 340 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047494 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047494&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 9982006 103978087 CHEMBL42668 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059804 CCCCCNC(=O)Nc1ccc(OCCCn2cnc(c2C)-c2ccccc2)cc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-16-28-27(33)30-24-15-14-23(19-25(24)31(3)4)34-18-11-17-32-20-29-26(21(32)2)22-12-8-7-9-13-22/h7-9,12-15,19-20H,5-6,10-11,16-18H2,1-4H3,(H2,28,30,33) YHSPVQDSCXFQQU-UHFFFAOYSA-N 50047497 1-{2-Dimethylamino-4-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42488 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 2400 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047497 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047497&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10412079 103978090 CHEMBL42488 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059805 CCCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-4-5-6-10-17-28-27(33)30-26-24(31(2)3)15-11-16-25(26)34-19-12-18-32-20-23(29-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,33) CSTKENWENAOKCJ-UHFFFAOYSA-N 50047493 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-hexyl-urea::CHEMBL42765 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 60 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047493 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047493&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10389684 103978086 CHEMBL42765 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059807 CCCCCNC(=O)Nc1c(OCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C25H33N5O2/c1-4-5-9-15-26-25(31)28-24-22(29(2)3)13-10-14-23(24)32-17-16-30-18-21(27-19-30)20-11-7-6-8-12-20/h6-8,10-14,18-19H,4-5,9,15-17H2,1-3H3,(H2,26,28,31) WEPJCYOFKWLPHG-UHFFFAOYSA-N 50047510 1-{2-Dimethylamino-6-[2-(4-phenyl-imidazol-1-yl)-ethoxy]-phenyl}-3-pentyl-urea::CHEMBL42813 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 170 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047510 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047510&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 9980424 103978103 CHEMBL42813 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059808 CCCCCNC(=O)Nc1cc(OCCCn2cnc(c2C)-c2ccccc2)ccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-16-28-27(33)30-24-19-23(14-15-25(24)31(3)4)34-18-11-17-32-20-29-26(21(32)2)22-12-8-7-9-13-22/h7-9,12-15,19-20H,5-6,10-11,16-18H2,1-4H3,(H2,28,30,33) CXZWCIQHJJIWSH-UHFFFAOYSA-N 50047498 1-{2-Dimethylamino-5-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL41992 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 410 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047498 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047498&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10367148 103978091 CHEMBL41992 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059809 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(CCCC)cc2)cccc1N(C)C InChI=1S/C30H43N5O2/c1-5-7-9-19-31-30(36)33-29-27(34(3)4)13-10-14-28(29)37-21-11-20-35-22-26(32-23-35)25-17-15-24(16-18-25)12-8-6-2/h10,13-18,22-23H,5-9,11-12,19-21H2,1-4H3,(H2,31,33,36) KGLIRNVBEZUXJQ-UHFFFAOYSA-N 50047517 1-(2-{3-[4-(4-Butyl-phenyl)-imidazol-1-yl]-propoxy}-6-dimethylamino-phenyl)-3-pentyl-urea::CHEMBL43505 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 54 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047517 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047517&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10346068 103978110 CHEMBL43505 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059810 CCCCCNC(=O)Nc1c(OCCCn2ccnc2-c2ccccc2)cccc1N(C)C InChI=1S/C26H35N5O2/c1-4-5-9-16-28-26(32)29-24-22(30(2)3)14-10-15-23(24)33-20-11-18-31-19-17-27-25(31)21-12-7-6-8-13-21/h6-8,10,12-15,17,19H,4-5,9,11,16,18,20H2,1-3H3,(H2,28,29,32) DMCPUDAATOTVFE-UHFFFAOYSA-N 50047512 1-{2-Dimethylamino-6-[3-(2-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL296421 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 380 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047512 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047512&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10095254 103978105 CHEMBL296421 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059811 CCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C23H29N5O2/c1-4-24-23(29)26-22-20(27(2)3)12-8-13-21(22)30-15-9-14-28-16-19(25-17-28)18-10-6-5-7-11-18/h5-8,10-13,16-17H,4,9,14-15H2,1-3H3,(H2,24,26,29) MEWZJCJSOWUGOM-UHFFFAOYSA-N 50047523 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-ethyl-urea::CHEMBL42807 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 870 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047523 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047523&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10069976 103978116 CHEMBL42807 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059813 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2cccc3ccccc23)cccc1N(C)C InChI=1S/C30H37N5O2/c1-4-5-8-18-31-30(36)33-29-27(34(2)3)16-10-17-28(29)37-20-11-19-35-21-26(32-22-35)25-15-9-13-23-12-6-7-14-24(23)25/h6-7,9-10,12-17,21-22H,4-5,8,11,18-20H2,1-3H3,(H2,31,33,36) KCNZHXUNAXRGCI-UHFFFAOYSA-N 50047502 1-{2-Dimethylamino-6-[3-(4-naphthalen-1-yl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42082 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 65 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047502 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047502&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 44288850 103978095 CHEMBL42082 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059814 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C26H35N5O2/c1-4-5-9-16-27-26(32)29-25-23(30(2)3)14-10-15-24(25)33-18-11-17-31-19-22(28-20-31)21-12-7-6-8-13-21/h6-8,10,12-15,19-20H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,32) CZOTZWJSMLDBSH-UHFFFAOYSA-N 50047495 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL440475 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 160 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047495 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047495&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 9824974 103978088 CHEMBL440475 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059815 CN(C)c1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NC1CCCC1 InChI=1S/C26H33N5O2/c1-30(2)23-14-8-15-24(25(23)29-26(32)28-21-12-6-7-13-21)33-17-9-16-31-18-22(27-19-31)20-10-4-3-5-11-20/h3-5,8,10-11,14-15,18-19,21H,6-7,9,12-13,16-17H2,1-2H3,(H2,28,29,32) MSLBOGVJFFFZOS-UHFFFAOYSA-N 50047506 1-Cyclopentyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL287842 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 240 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047506 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047506&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10456284 103978099 CHEMBL287842 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059817 CCCCCNC(=O)Nc1c(OCCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-4-5-9-17-28-27(33)30-26-24(31(2)3)15-12-16-25(26)34-19-11-10-18-32-20-23(29-21-32)22-13-7-6-8-14-22/h6-8,12-16,20-21H,4-5,9-11,17-19H2,1-3H3,(H2,28,30,33) BEZRXKMOKQLKQE-UHFFFAOYSA-N 50047504 1-{2-Dimethylamino-6-[4-(4-phenyl-imidazol-1-yl)-butoxy]-phenyl}-3-pentyl-urea::CHEMBL44358 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 160 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047504 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047504&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10073104 103978097 CHEMBL44358 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059818 CCCCCNC(=O)Nc1c(OCCCn2cnc(C)c2-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-25-23(31(3)4)15-11-16-24(25)34-19-12-18-32-20-29-21(2)26(32)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) CVMNIXDUMPWJQL-UHFFFAOYSA-N 50047501 1-{2-Dimethylamino-6-[3-(4-methyl-5-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL43362 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 85 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047501 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047501&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10412078 103978094 CHEMBL43362 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059820 CCCCCCCN(Cc1ccc(CC(C)(C)C)cc1)C(=O)Nc1ccc(F)cc1F InChI=1S/C26H36F2N2O/c1-5-6-7-8-9-16-30(25(31)29-24-15-14-22(27)17-23(24)28)19-21-12-10-20(11-13-21)18-26(2,3)4/h10-15,17H,5-9,16,18-19H2,1-4H3,(H,29,31) QKJLDOBXDUVGEE-UHFFFAOYSA-N 50022279 CL-277082::3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)-benzyl]-1-heptyl-urea::CHEMBL277986 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 900 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022279 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022279&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 125893 103932899 CHEMBL277986 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059821 CCCCCNC(=O)Nc1c(ccc(C)c1OCCCn1cnc(c1)-c1ccccc1)N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-16-28-27(33)30-25-24(31(3)4)15-14-21(2)26(25)34-18-11-17-32-19-23(29-20-32)22-12-8-7-9-13-22/h7-9,12-15,19-20H,5-6,10-11,16-18H2,1-4H3,(H2,28,30,33) FEPXBGTVAGOACR-UHFFFAOYSA-N 50047521 1-{6-Dimethylamino-3-methyl-2-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL291173 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 250 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047521 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047521&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10367147 103978114 CHEMBL291173 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059822 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) MRSWFEPPCGEHKT-UHFFFAOYSA-N 50047499 1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL296094 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 110 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047499&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10027414 103978092 CHEMBL296094 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059824 CCCCCNC(=O)Nc1c(CCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C28H39N5O/c1-5-6-11-19-29-28(34)31-27-24(17-13-18-25(27)32(3)4)16-10-12-20-33-21-30-26(22(33)2)23-14-8-7-9-15-23/h7-9,13-15,17-18,21H,5-6,10-12,16,19-20H2,1-4H3,(H2,29,31,34) FLASAYJQWIWHOK-UHFFFAOYSA-N 50047505 1-{2-Dimethylamino-6-[4-(5-methyl-4-phenyl-imidazol-1-yl)-butyl]-phenyl}-3-pentyl-urea::CHEMBL43095 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 140 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047505 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047505&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10457030 103978098 CHEMBL43095 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059828 CN(C)c1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NC(C)(C)C InChI=1S/C25H33N5O2/c1-25(2,3)28-24(31)27-23-21(29(4)5)13-9-14-22(23)32-16-10-15-30-17-20(26-18-30)19-11-7-6-8-12-19/h6-9,11-14,17-18H,10,15-16H2,1-5H3,(H2,27,28,31) PIZKWMLQOPEHGM-UHFFFAOYSA-N 50047500 1-tert-Butyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL298486 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 990 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047500 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047500&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10003115 103978093 CHEMBL298486 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059829 CCCCCNC(=O)N(C)c1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)31(4)26-24(30(2)3)15-11-16-25(26)34-19-12-18-32-20-23(29-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H,28,33) QGDAAIPGJQYTCF-UHFFFAOYSA-N 50047516 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-1-methyl-3-pentyl-urea::CHEMBL42395 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 400 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047516 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047516&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 11754155 103978109 CHEMBL42395 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059830 CCCCCNC(=O)Nc1c(OCCCn2cc(nc2C)-c2ccc(OC)cc2)cccc1N(C)C InChI=1S/C28H39N5O3/c1-6-7-8-17-29-28(34)31-27-25(32(3)4)11-9-12-26(27)36-19-10-18-33-20-24(30-21(33)2)22-13-15-23(35-5)16-14-22/h9,11-16,20H,6-8,10,17-19H2,1-5H3,(H2,29,31,34) WKPWXRIKPSERBM-UHFFFAOYSA-N 50047508 1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-2-methyl-imidazol-1-yl]-propoxy}-phenyl)-3-pentyl-urea::CHEMBL298440 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 160 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047508 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047508&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10323444 103978101 CHEMBL298440 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059831 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33) MRSWFEPPCGEHKT-UHFFFAOYSA-N 50047499 1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL296094 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 43 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047499 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047499&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10027414 103978092 CHEMBL296094 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059833 CCCCCNC(=O)Nc1c(OCCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C27H37N5O2/c1-4-5-9-17-28-27(33)30-26-24(31(2)3)15-12-16-25(26)34-19-11-10-18-32-20-23(29-21-32)22-13-7-6-8-14-22/h6-8,12-16,20-21H,4-5,9-11,17-19H2,1-3H3,(H2,28,30,33) BEZRXKMOKQLKQE-UHFFFAOYSA-N 50047504 1-{2-Dimethylamino-6-[4-(4-phenyl-imidazol-1-yl)-butoxy]-phenyl}-3-pentyl-urea::CHEMBL44358 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 780 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047504 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047504&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10073104 103978097 CHEMBL44358 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059834 CN(C)c1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NC1CCCCC1 InChI=1S/C27H35N5O2/c1-31(2)24-15-9-16-25(26(24)30-27(33)29-22-13-7-4-8-14-22)34-18-10-17-32-19-23(28-20-32)21-11-5-3-6-12-21/h3,5-6,9,11-12,15-16,19-20,22H,4,7-8,10,13-14,17-18H2,1-2H3,(H2,29,30,33) QOWNCIVDLGZPNQ-UHFFFAOYSA-N 50047520 1-Cyclohexyl-3-{2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-urea::CHEMBL290627 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 1070 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047520 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047520&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10027328 103978113 CHEMBL290627 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059835 CCCCCC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C26H34N4O2/c1-4-5-7-16-25(31)28-26-23(29(2)3)14-10-15-24(26)32-18-11-17-30-19-22(27-20-30)21-12-8-6-9-13-21/h6,8-10,12-15,19-20H,4-5,7,11,16-18H2,1-3H3,(H,28,31) JJZDMZHYPPAQNX-UHFFFAOYSA-N 50047515 Hexanoic acid {2-dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-amide::CHEMBL46738 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 100 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047515 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047515&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 11743656 103978108 CHEMBL46738 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059838 CCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C23H29N5O2/c1-4-24-23(29)26-22-20(27(2)3)12-8-13-21(22)30-15-9-14-28-16-19(25-17-28)18-10-6-5-7-11-18/h5-8,10-13,16-17H,4,9,14-15H2,1-3H3,(H2,24,26,29) MEWZJCJSOWUGOM-UHFFFAOYSA-N 50047523 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-ethyl-urea::CHEMBL42807 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus >10000 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047523 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047523&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10069976 103978116 CHEMBL42807 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059840 CCCCCNC(=O)Nc1c(CCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C28H39N5O/c1-5-6-11-19-29-28(34)31-27-24(17-13-18-25(27)32(3)4)16-10-12-20-33-21-30-26(22(33)2)23-14-8-7-9-15-23/h7-9,13-15,17-18,21H,5-6,10-12,16,19-20H2,1-4H3,(H2,29,31,34) FLASAYJQWIWHOK-UHFFFAOYSA-N 50047505 1-{2-Dimethylamino-6-[4-(5-methyl-4-phenyl-imidazol-1-yl)-butyl]-phenyl}-3-pentyl-urea::CHEMBL43095 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 170 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047505 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047505&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10457030 103978098 CHEMBL43095 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059841 CCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C InChI=1S/C24H31N5O2/c1-4-14-25-24(30)27-23-21(28(2)3)12-8-13-22(23)31-16-9-15-29-17-20(26-18-29)19-10-6-5-7-11-19/h5-8,10-13,17-18H,4,9,14-16H2,1-3H3,(H2,25,27,30) VYWKZXUTPFZFLB-UHFFFAOYSA-N 50047507 1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-propyl-urea::CHEMBL41960 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 7230 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047507 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047507&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10025201 103978100 CHEMBL41960 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059842 CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(OC)cc2)cccc1N(C)C InChI=1S/C27H37N5O3/c1-5-6-7-16-28-27(33)30-26-24(31(2)3)10-8-11-25(26)35-18-9-17-32-19-23(29-20-32)21-12-14-22(34-4)15-13-21/h8,10-15,19-20H,5-7,9,16-18H2,1-4H3,(H2,28,30,33) FETJCLFYGUTKOI-UHFFFAOYSA-N 50047526 1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-imidazol-1-yl]-propoxy}-phenyl)-3-pentyl-urea::CHEMBL42942 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 59 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047526 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047526&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10412851 103978119 CHEMBL42942 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059843 CCCCCNC(=O)Nc1c(NCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C InChI=1S/C27H38N6O/c1-5-6-10-17-29-27(34)31-26-23(15-11-16-24(26)32(3)4)28-18-12-19-33-20-30-25(21(33)2)22-13-8-7-9-14-22/h7-9,11,13-16,20,28H,5-6,10,12,17-19H2,1-4H3,(H2,29,31,34) NMLREFBZXBPANR-UHFFFAOYSA-N 50047518 1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propylamino]-phenyl}-3-pentyl-urea::CHEMBL41127 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 2200 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047518 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047518&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10367104 103978111 CHEMBL41127 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059844 CCCCCNC(=O)Nc1c(OCCCn2cnc3ccccc23)cccc1N(C)C InChI=1S/C24H33N5O2/c1-4-5-8-15-25-24(30)27-23-21(28(2)3)13-9-14-22(23)31-17-10-16-29-18-26-19-11-6-7-12-20(19)29/h6-7,9,11-14,18H,4-5,8,10,15-17H2,1-3H3,(H2,25,27,30) AFXKWXLBLYFGRF-UHFFFAOYSA-N 50047528 1-[2-(3-Benzoimidazol-1-yl-propoxy)-6-dimethylamino-phenyl]-3-pentyl-urea::CHEMBL40516 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 180 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047528 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047528&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10251723 103978121 CHEMBL40516 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059845 CCCCCNC(=O)Nc1ccc(OCCCn2cnc(c2C)-c2ccccc2)cc1N(C)C InChI=1S/C27H37N5O2/c1-5-6-10-16-28-27(33)30-24-15-14-23(19-25(24)31(3)4)34-18-11-17-32-20-29-26(21(32)2)22-12-8-7-9-13-22/h7-9,12-15,19-20H,5-6,10-11,16-18H2,1-4H3,(H2,28,30,33) YHSPVQDSCXFQQU-UHFFFAOYSA-N 50047497 1-{2-Dimethylamino-4-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL42488 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 1500 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047497 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047497&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10412079 103978090 CHEMBL42488 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214 50059846 CCCCCNC(=O)Nc1c(OCCCn2cc(nc2C)-c2ccc(OC)cc2)cccc1N(C)C InChI=1S/C28H39N5O3/c1-6-7-8-17-29-28(34)31-27-25(32(3)4)11-9-12-26(27)36-19-10-18-33-20-24(30-21(33)2)22-13-15-23(35-5)16-14-22/h9,11-16,20H,6-8,10,17-19H2,1-5H3,(H2,29,31,34) WKPWXRIKPSERBM-UHFFFAOYSA-N 50047508 1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-2-methyl-imidazol-1-yl]-propoxy}-phenyl)-3-pentyl-urea::CHEMBL298440 Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus 730 ChEMBL 10.1021/jm00063a013 10.7270/Q22B8X4P 8496930 Kimura, T; Takase, Y; Hayashi, K; Tanaka, H; Ohtsuka, I; Saeki, T; Kogushi, M; Yamada, T; Fujimori, T; Saitou, I 6/21/1993 11/10/2009 Eisai http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047508 http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000059&target=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/rwd/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047508&enzyme=Acyl-CoA%3Acholesterol+acyltransferase&column=ki&startPg=0&Increment=50&submit=Search 10323444 103978101 CHEMBL298440 1 PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF Sterol O-acyltransferase 1 Q95214_RABIT Q95214